Fred Liers PhD juice cleanse kidneys Irena OssolaBack in July, HPDI’s sponsored athlete Irena Ossola was up in Canada training for and winning bike races. After months on the road of training, racing, and travel—and toward the end of the season—she experienced an episode of cramping. Blood tests showed a condition of rhabdomyolysis.

In rhabdomyolosis, damaged skeletal striated muscle rapidly breaks down. Consequently, the breakdown products of the damaged muscle cells are released into the bloodstream. Some of the products, including the protein myoglobin, can harm the kidneys.

Irena Ossola and Fred Liers juice cleanse

Cyclist Irena Ossola and Fred Liers discuss HPDI supplements as part of peak-performance health.

Extreme or strenuous physical exercise is among the known risk factors for rhabdomyolosis. This is particularly the case when a person is dehydrated. Being an elite athlete who endures training, racing, and traveling for months, it is no surprise that Irena could experience this condition.

Fortunately, Irena’s cramping ended after a few days of rest, hydration, and electrolyte intake as directed by her doctor.

Having time available after her recovery, Irena decided to embark upon a juice cleanse.

She would start with a kidney flush. That made sense to her not only because she had the time available, but also because while she had resumed normal activities, she hoped to cleanse her system so she could return to training in an optimal condition of readiness.

After careful consideration, Irena plans and prepares for a five-day juice cleanse. She obtains a high-quality Breville juicer, kidney-specific herbal teas and tinctures, Rejuvenate! superfoods, and lots of fresh organic produce.

Her plan includes consuming raw foods on the first and last days, and just freshly made vegetable and fruit juices (along with teas, tinctures, and Rejuvenate! superfoods) on the middle days. She will consume up to one gallon of fresh juice daily.

She will not stop her training altogether, but not having to travel or train intensely for races means she can match her training level to her physical capacity during the cleanse.

Irena documents her daily progress in her blog. She ends up completing a full week (seven days) on her juice cleanse. At the end of her journey, she writes: “My body feels so good I am happy to have completed this journey.”

Below we include Irena’s full article complete with all entries and some of her photos. ~~~


by Irena Ossola
(originally published July 2015)


I have researched, discussed, and read so much about juice cleanses and think I am to tackle it for five days of rebooting my system.

After months of training, racing, travel, and other life stresses I decided I need to cleanse my body of all the toxins and get a fresh start for my kidneys. I returned from a long few months on the road and am just getting over an episode of cramping where blood tests showed rhabdomyolysis in my kidneys.

The doctor had me get an IV of 2L of fluid to help hydrate and flush my kidneys. After a couple more days of rest and looooots of pedialite and hydration the cramping stopped and I felt back to normal, at least with walking and everyday activity.

Training will take a little longer to rebuild however, so it is the perfect time for a juice cleanse. Without the big intensity workouts that require a lot of energy, and good recovery, I am able to stick with just juice and let my body recover.

Discussing a plan and information with Fred Liers, and Dr. Hank Liers of Health Products Distributors, Inc., we have put together the best program and technique for me as a professional cyclist to tackle this cleanse.

Over the next few days I will be posting daily updates about my journey. I will also include advice, recipes, pictures, and discussion of how I feel while still training and going through this cleanse/diet.


Irena Ossola Kidney Cleanse Juice

Rejuvenate! Plus superfood, detox tea, and other supplies.


Day 1 and 5: Raw Foods – Eating just fruits and vegetables to ease my body into the more restricted and intense cleanse of just juice

Day 2, 3, 4: Just Juice – Drinking as much and as often as I feel. But only juices with a combo of fruits and vegetables to give me enough vitamins, minerals, and energy to keep my day going and keep training (even with no solid food).

Mornings: Start out with a Lemonade drink first off to get my system going. Then 15–30 min later I drink 8–16 oz of Detox Tea. Then about 1 hr later I’m getting hungry and it’s juice time.

Lemonade Recipe: 8 oz purified water, 4 oz lemon/lime juice (about 3 lemons and 1 lime), cayenne pepper (to taste as things get spicy), small amount of maple syrup or stevia to sweeten ( I have also just been toughing it out and doing without).

Irena Ossola juice cleanse lemonade

Making lemonade in the kitchen.

Detox Tea: I’m in a crunch for time and money so I just bought the Yogi Brand Peach Detox tea and put 2 bags into 3 quarts of water. 1 quart I drink for my morning tea routine, and the rest I drink throughout the day. The kidney cleanse also calls for taking tictures with the tea. These are reduced down herbal liquids that you can find at whole foods or ordered online.

Fred Liers of Health Products Distributors, Inc., recommended getting a couple different ones since I was in a crunch on time and not able to order the correct ones. I found the Uva Ursi at Whole Foods, but they didn’t have the Parsley or Juniper Berry. I took 2 shot glasses almost full of tea and put in a dropper of the tincture, then took them like a shot before drinking my 8–16 oz of tea.

Irena Ossola urva ursi kidney cleanse

Uva Ursi tincture.


Today I started the cleanse with the Lemonade and Detox Tea but was happy to not jump in head first to the strictly juice just yet.

I ate an apple, banana, baby carrots, and a salad for lunch and dinner which included an avocado to get some protein and fats (you can also include nuts since that is considered raw food). I also threw in some watermelon and strawberries into the salad which made it extra good.

Since I got my juicer and wanted to get it for a spin and have some fun experimenting I did make some juices and drank those during the day also.

This first day wasn’t too hard since I am already used to eating a lot of salad and fruits. Just not having any meat or protein was tougher and felt a bit hungrier and meals didn’t hold over as long

I also noticed I was peeing A LOT more just from the tea and juices. This will probably be an indication of the bathroom usage to come in the upcoming days, haha.

Training: 1’20″ ride easy just to feel out legs and get some exercise on the bike. Swam about 30″ total, going back and forth between hot tub and pool to get contrast and circulation in muscles.

Irena Ossola salad raw food cleanse

I consumed raw foods the day before my cleanse.


Started off with my Lemonade, the sourness is already a tough chug but beware of that cayenne. Added too much this morning and it definitely woke me up.

After drinking the tea (20 min after the lemonade) I was surprisingly not very hungry during the morning. I had my first juice at 9:30ish and usually if I don’t eat soon after waking up I’m starving. This was a surprisingly common feeling all day. I kept drinking throughout the day but even when I was riding or swimming I didn’t feel weak or tired at all. Throughout the day I’ve felt pretty good overall.

I am enjoying the lack of thinking in this. I don’t have to think about what I’ll have post ride, or for lunch, or for dinner, because it’s already decided for me…JUICE! No dealing with cravings or suppressing hunger or getting snacks to hold off till meals. I like just being able to drink whenever and as much juice as I want. I feel lighter and no stomach issues.

Irena Ossola Breville Juicer

I use a Breville juicer.

cleanse juice bottles

Yummy juice!

Today’s Flavors:

1 –    Kale, chard, cucumber, celery, beets, carrots, few strawberries, lime rind, about 1/2 scoop Rejuvenate!

2 –    More Fruit (base from #1) – + Apple, orange, banana, more strawberries, watermelon, lemon/lime rind, ginger

3 –    Garlic (base from #1) – + Garlic clove, parsley, ginger

Review of Juices:

#2 – Definitely sweeter and lighter on flavor

#3 – The garlic juice had a funky aftertaste from the garlic and needed the parsley to cut the strong flavor, but probably put too much because the juice came out a bit spicy. Added more Rejuvenate to this one and helped bring down the intensity from the garlic.

Training: 2’ 10″ ride relaxed and feeling good. Not feeling hungry in the ride, but had to stop for a pee break (that seems to be a common theme today). Hungry at end of the ride and juice was great for recovery. Swam 40″ total, with some back and forth to the hot tub for more circulation.

Felt good and never got hungry since I had juice before and after exercise. That is one thing that was important today with exercising, is to keep juice and hydration available at all times. Pre and post is so important for training and on a cleanse you can’t neglect your body’s needed nutrients.

irena ossola breville juicer

irena ossola juicer bowl


I didn’t even wake up very hungry, and once I had my Lemonade and Tea I felt full already before even having any juice. My routine has gotten pretty on point also; I get up and right away put on water for tea, then I start squeezing the lemons/lime for lemonade.

Once I’m done making the lemonade I sip on it while the tea steeps and I prep for juice. Washing all the produce and getting bottles ready. As I drink down the tea it’s juicing time. Lay out the spread and juice out 3 or 4 quarts. I am having a lot of fun with different recipes and playing with the flavors where each bottle is different.

Today’s Flavors:

1 –    The BASE – Kale, chard, cucumber, celery, beets, carrots, few strawberries, lime rind, about 1/2 scoop Rejuvenate!

2 –    More Fruit (base from #1) – + Apple, orange, banana, more strawberries, watermelon, lemon/lime rind, ginger but no carrots

3 –    Garlic (base from #1) – + Garlic clove, parsley, ginger

4 –    Base but added ginger and parsley

Review of Juices:

#2 –    Is probably my favorite, sweeter and lighter without any harder flavors like with the garlic

#3 –    This one makes me feel like I’m being healthy, cause it doesn’t taste so great, haha.

#4 –    This one had a little kick with the parsley and ginger, definitely tasty!

Juicing Tips: As you can see from the pictures juicing can get messy. I recommend getting all the ingredients and bottles ready and layed out so you can juice out more smoothly. Lay out newspaper under the juicer so and splattering or spilling is a lot easier to clean up. Beware of beets!! They stain and any platters in the way or cabinets needs to be wiped immediately, or it’ll leave a mark. The juicer is easy to wash, without oils it makes a simple rinse quick and simple.

Overall today was a little tougher, and I’m only 3 days in!! How the heck do people do this for months?! The morning and all day was pretty good in not feeling very hungry, but my energy level was definitely lower.

I got about halfway through my ride and started feeling my muscles getting tired even though I wasn’t even going very hard. My mind wasn’t focusing as well (bonktown USA) and wanted to finish the ride, but I stuck it out and finished the training.

Same thing when I went swimming, just feeling like a nap and not high on energy at all. My body is feeling great, clean and light. It’s just that since I am so used to having constant protein and other nutrition inputs this change has come with a little getting used to.


One thing I noticed today is that waking up and getting out of bed was easier and I was ready to get the day going. I don’t feel hungry or sluggish in the morning but found my juicing routine has been pretty nice in the morning. What did hit hard to day was feeling tired in training and then in the evening before bed.

This cleanse is definitely not for the high volume athlete or intense training season. I am glad to be doing light riding and swimming, but I still feel my body tired about 1 hr into a ride and just want to pull over for a nap. I make sure to drink plenty of juice before and after my training for energy, and lots of water during for hydration.

Tip: Make sure you do the cleanse when you can exercise but don’t have intense, high volume, or super focused training. This will drain some of your energy, but you will feel so much better through and after the process is complete.

Today’s Flavors:

1 –    The Base – But no red beets, plus squash, no watermelon + Rejuvenate! mix

2 –    Fruit – + Raspberries and watermelon + Rejuvenate! mix

3 –    Garlic, parsley, squash, no strawberries + Rejuvenate! mix

4 –    Mix assorted + Rejuvenate! mix

Rejuvenate! Mix – 1/2 scoop of Rejuvenate! Plus, 1/3 scoop of Rejuvenate! Berries and Herbs, 1/4 scoop of Rejuvenate! Original (Greens).

By adding this Rejuvenate! superfood mix to my juices it has given me more energy and adds more vitamins and minerals so I am not just drinking the juice alone but also getting other benefits and nutrients that my body needs. There is also extra protein that adds some more substance to the juice to hold my appetite over.

Irena Ossola bicycle training

Training in New Mexico.


Today should be the last day and the raw food day, but I’ve decided to go for a whole week of cleansing. So I will make it five days of just juice and two days of raw food on either end. I am feeling good with the juice and something in me doesn’t want to stop before complete a full week.

My biggest tip for today when doing the cleanse is to not hold back on the amount of juice you make or drink. It doesn’t matter how much you drank the first day because as the days go on your body will need more nutrients as it burns through stores.

I found that I am losing a lot of weight, not intentionally, but just because of the cleanse and exercise. So if that is your goal then don’t think you have to stick to just a certain volume everyday. Each day I have increased my juice intake by at least two cups. Today I am at four 32 oz bottles (not completely full), and the first day I only had three. Listen to your body and give it what it needs.

Today’s Flavors:

1 –    The Base – + Garlic, parsley, banana, squash, no red beets

2 –    Fruit – The Base – +  Watermelon, strawberries, raspberries, ginger, apple, banana

3 –    Garlic – Garlic, parsley, ginger, red beets, watermelon, no apple

4 –    What was left –  Ginger, apples, kale, beets

I’ve upped the garlic and banana; since garlic is so good for vitamin C and cleansing and banana has some extra calories and energy to run on.


So everyone has said “Wow, only juice, you must be so hungry.” But I’m really not, and I haven’t really had big cravings for anything either. Getting my body into the routine, it has settled and is happy with the nutrients of the juice.

I am happy to start eating real food again tomorrow, but definitely very happy I did this and went through the experience of cleansing. Not just for my physical health but also mental. It was great to refocus on what is important for my training and life beyond just meals and satiating hunger through the day. This helped me rebalance and feel my body in a state of renewal.

One concern for most people when doing something like this is time and money. For time, if you think about the time you take to either make and eat meals or get food at a store or restaurant it takes up about 2–3 hours per day, give or take. I have been getting up each morning and it takes me about 1.5 hrs for prep, juicing, and cleanup. And I drink throughout the day so I am not having to sit down with a plate or meal. It really is a great on-the-go kind of plan.

For money, I have saved all my receipts from the grocery store, so after tomorrow is over I will calculate all of my expenses for this experience. But it has cost me roughly $15 – $20 per day. And that is completely organic produce. I have gotten a couple things from my dad’s garden (which is obviously ideal), but most was store bought.

Thinking about what people spend on meals and eating out, that can get well over $20 per day. And getting juice at a shop or store, can run $5 just for a quart, and I am drinking well over four quarts per day. This is definitely an economical diet if done correctly.

Today’s Flavors:

Basically the same, but today I threw in peaches and more berries…I also strategically put in a banana into my first and second juices, so that before my ride and after I would have the extra sugar and potassium.

Irena Ossola Rejuvenate superfood mix

My superfood mix uses all three Rejuvenate! superfoods.


Today was the final day of official cleansing and a day of raw food. I think my body knew it was the day because I woke up hungry for the first time all week. I still did my lemonade/tea and juicing for the day as I wanted to keep my hydration up and keep the routine.

It was nice to think about what I would eat for my first food back, and I went for a banana this morning. Seemed appropriate since bananas are the common cure for cramps, and that’s why I did the cleanse. It was so great tasting and funny thing is, the chewing sensation was weird to get used to again.

The rest of the day was pretty normal and not any huge cravings, but I had half an avocado before my workout and the other half after.

I was surprised to not eat more but just didn’t feel like it, my appetite was pretty slim. But I was definitely satisfied and could say full after just eating a little bit.

In the evening for dinner I went out and had an amazing salad. My body feels so good, I am happy to have completed this journey.

Irena Ossola juice cleanse

My first solid food in a week!

I did not do this cleanse for weight loss, but to clean out my body and help my kidneys and system recover after the fatigue of cramping. But considering I was in a down time with training it was the perfect time to do it and also shed a couple pounds before harder training again.

So I will say it was incredible to see my weight change as each day passed. I started out at 148 pounds which is pretty normal for me and what I have been racing at this season, today I weighed myself in the morning and was 143.

I am pretty shocked by how much I lost in this short time. And I wasn’t even holding back or feeling the pains someone usually feels in dieting or losing weight, I drank as much as I wanted and never felt hungry or strong urges to eat.

I would really recommend this cleanse to anyone looking to clean up their system and/or to shed some unwanted weight.

It is so important to take on things like this with a smart and prepared approach with the intent of health and well being, not just to get skinny or for looks. If that is the drive then it’s more likely the weight will be put right back on, because it’s about a lifestyle and making good choices for the benefit of your body.

To eat well and be happy with your body is the most important thing.

So I hope this blog post has helped anyone looking to start or research doing a kidney cleanse. Or even just reading along as I go though along my road as a professional cyclist.

It has been an amazing experience and I plan to do it again before my season of hard training starts in the fall/winter.


irena ossola stationary bicycle training


Read Irena’s juice cleanse article on her blog (OssolaSport.com):



Contact Us:

You can reach HPDI by calling 1-800-228-4265, email support(at)IntegratedHealth.com, or visit the retail website: www.IntegratedHealth.com

Health care professionals and retailers can apply for wholesale account, which includes access to the HPDI reseller website: www.HealthProductsDistributors.com



Fred Liers PhD shingles herpes chickenpoxIf you’ve ever experienced shingles, or witnessed someone close to you experience it, then you probably know it’s a condition to avoid if at all possible. I experienced it, as have several persons I know.

Essentially, shingles is a commonly occurring viral condition caused by a reactivation of varicella zoster virus (Chickenpox). It is characterized by the development of a rash usually either on the right or left side of the body, and sometimes the face. In severe cases, vision loss may occur. One person I know lost hearing in one ear.

The rash is typically accompanied by varying levels of nerve pain and tingling sensations. The rash may disappear within one month. Yet, in some cases there may be ongoing nerve pain that can last for months or years. Shingles may reoccur. I know of several persons who have had it more than once. Others say they can feel it ‘coming on’ and take immediate steps to stop a recurrence.

I experienced what might be considered a ‘mild’ case of shingles. Still, it was probably three weeks before my symptoms mostly abated, and four or five weeks before I was felt completely normal.

First, there was a week of increased sensitivity of my skin to touch in around the affected areas, as well as tingling sensations, and pain radiating from my lower back down the back and inside of my left leg. I also experienced mild fever, malaise, and low energy. All this before any rash appeared and prior to my awareness that my symptoms were caused by shingles.

Acupuncture can be helpful for shingles pain.

Acupuncture can be helpful for shingles pain.

Then the rash started at my sacrum and ran in patches down the inside of my left leg to my ankle. The nerve pain made it increasingly difficult to walk comfortably, and I experienced major fatigue. I continued to feel intense tingling, shooting nerve pain, and sensitive skin for several weeks.

When I say I had a relatively mild case of shingles, I don’t mean to diminish my experience of pain or fatigue. But I know other people whose pain definitively was greater than mine, and whose symptoms lasted longer. In some cases, they didn’t know what condition they were dealing with for days or weeks.

Fortunately, I acted immediately after I knew I had shingles. In dealing with shingles it is important that the individual rest and take measures to strengthen and support the immune system.

I would say that the most important actions I took were to boost nutrient intake (including higher intake of vitamin C), and take the amino acid l-lysine, olive leaf extract, Immune-Assist™ mushroom extract, and Prescript-Assist probiotic & prebiotic formula (soil-based organisms).

Please refer to the recommendations in the table (below), which was developed by my father, Hank Liers, PhD, several years ago. He refines the recommedations on an ongoing basis. Indeed, he was instrumental in supporting my recovery during the time I had shingles.

Also helpful were essential oils (lavender, lemon balm, helichrysum) rubbed directly onto the rash 2–3 times daily, as well as baths using magnesium chloride (oil or flakes). I also sprayed Polyvalent Silver, Warrior Mist, and Warrior Sleep on the rash.

Warrior Mist is formulated to stop pain. Warrior Sleep contains lavender. I often applied the Warrior Sleep at night. When I applied it during the day it did not overly relax me probably because I only applied small amounts to my leg. When seeking to induce sleep or relaxation, I usually apply larger amounts of it to my neck and face.

Regarding essential oils, be sure to follow the recommendations on the bottle. If necessary, you can dilute oils using a carrier oil (like almond or coconut oil) if your skin is particularly sensitive.

essential oils lavender shingles

Essentials oils such as lavender can be helpful for shingles.

I rested a few more hours daily for a couple weeks, and longer during peak periods of fatigue. However, I took short walks or engaged in gentle exercise whenever possible. I exposed the rash to sunshine for 10–15 minutes every day.

I had two acupuncture treatments, which significantly reduced pain. After each treatment, I noticed it was easier to walk normally. During the first treatment I felt shooting, needle-like sensations run the length of my left leg. These sensations were more intense in the areas most greatly affected. Thereafter pain and tingling was less noticeable. This reduction hastened my return to normal activity.

Several weeks after onset of the rash, I performed a juice cleanse (liver flush), which lasted nine days. I felt noticeably greater energy during and after the cleanse. I believe it powerfully supported my body’s healing process.

During the time on my juice flush, I consumed only fresh vegetable juices, and herbal teas and tinctures. The fresh, organic juice rejuvenated me, and it gave my body a break from having to digest solid food. Thus, I gained significant nutritional benefits while simultaneously cleansing and conserving energy normally required for digestion and related metabolic processes.


It probably helped I was already eating a healthy diet and that I routinely take all the foundational supplements (multivitamins, essential fats, vitamin C, Rejuvenate! superfoods) listed in the table below.

I feel that Rejuvenate! superfoods were particularly instrumental in my recovery. Whereas I regularly take 1–4 scoops of Rejuvenate! superfoods daily, I increased my dose closer to 5–8 scoops daily. I emphasized Rejuvenate! Original, yet also took higher amounts of Rejuvenate! PLUS and Rejuvenate! Berries & Herbs.

I consume a healthy diet that is mostly organic, relatively high in greens and vegetables, and low in simple carbohydrates. I eat lean proteins (fish like wild-caught salmon), complex carbohydrates (like broccoli), and a few whole grains (organic brown rice).

Notably during my time with shingles, I reduced my intake of foods high in arginine. I also increased my intake of foods high in lysine. A balance of  these two amino acids in favor of lysine is known to lessen the activity of the virus.

It may be that my case of shingles was relatively less severe due to the fact that my nutrition is fairly solid. For had my nutritional status and/or my immune system been compromised, I believe my ability to fight the virus would have been correspondingly lessened.

What follows below is the Table (1.0) and additional information comprising the shingles recommendations, as developed by Hank Liers, PhD.


Description Morning Noon Evening Night Comments
Pro C (180 caps) ™ 2 caps
1 cap
2 caps
1 cap
2 caps
1 cap
Take with meals. Start with 2 caps per meal for the first 6 days, then reduce to 1 cap per meal.
Prescript-Assist®  (90 caps) 1 cap 1 cap Take 10–20 minutes before meals. Go to 1 cap daily after 30 days.
Multi Two Tabs (180 tabs) – Multivitamin or
Mighty Multi-Vite!
1 tab
2 caps
1 tab
2 caps
Take with meals.
L-Lysine — 500 mg 1-2 caps 1-2 caps Take 30 minutes before or 2 hours after meals.
Double Zinc Plus (100 vcaps) 1 cap Take with meals.
Bone Guardian Tabs or
Bone Jour™
2 tabs
3 caps
2 tabs
3 caps
Take with meals.
Buffered Vitamin C,
Buffered C-1,000 (250 tabs) — 1,000 mg (1 gm)
or Buffered C Powder (1/2 lb) (1/4 tsp = 1 gm)
1 tab
1/4 tsp
1 tab
1/4 tsp
1 tab
1/4 tsp
1 tab
1/4 tsp
Best with meals, but other times are okay.  Start with 1 tab or 1/4 rounded tsp twice a day and add another 1 tablet or 1/4 tsp every few days until you are taking 4 tablets or 1 rounded tsp per day.
Essential Fats plus E (90 softgels) 1 cap 1 cap 1 cap 1 cap Take with meals/snacks.
Complete E (60 softgels) 1 cap 1 cap Take with meals.  In addition, rub the contents of a capsule on affected area twice per day.
Olive Leaf Extract 500 mg 2 caps 2 caps 2 caps 2 caps Take between meals with 1 1/2 –2 glasses of water.
Rejuvenate! Plus or
Rejuvenate Berries & Herbs
1 scoop
1 scoop
1 scoop
1 scoop
Take as snack or in fruit smoothie.


Additional nutrients that may be helpful include Echinacea (as drops or capsules), N-Acetyl-L-Cysteine (NAC) 500 mg (100 caps) NAC (2 gms per day), and Immune-Assist™ (2 capsules 3 times per day).

Rub essential oils such as helichrysum, lemon balm, frankincense, and lavender and/or spray Silver Biotics Polyvalent Silver (16 oz) solution several times daily on the affected areas.


Consume a diet relativley high in lysine and relatively low in arginine.

Consume high fiber foods such as organic vegetables (including 16 oz per day of fresh juices from carrot, celery, beets, cabbage, etc.), organic fruits, whole grains (e.g., brown rice, millet, and quinoa), beans, nuts and seeds (sunflower, chia, flax, pumpkin, almond, walnut and sesame in small amounts are good).

If you consume animal products, eat only organic lean meats, organic poultry and fish, including salmon, sardines, mackerel, trout, and bluefish (all of which are high in omega-3s).

Try eating Hank’s Vegetable Soup several times a week. Avoid sweets (sugar), processed/refined food (white bread and pasta), preservatives, and artificial flavors and colors.

If you have a Rife machine available, then use the shingles and antiviral codes on a daily basis.

Take baths with Ancient Minerals Magnesium Oil/Flakes/Gel (1 cup) and baking soda (1 cup).


Contact Us:

You can reach HPDI by calling 1-800-228-4265, email support(at)IntegratedHealth.com, or visit the retail website: www.IntegratedHealth.com

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Fred Liers PhD chlorellaRejuvenate!™ superfoods are the world’s first superfoods formulated specifically to provide therapeutic levels of dietary nucleic acids (RNA, DNA, nucleosides, and nucleotides). HPDI currently offers three versions: Rejuvenate! Original, Rejuvenate! PLUS, and Rejuvenate! Berries & Herbs.

All three Rejuvenate! formulas provide at least 340 mg of dietary nucleic acids per serving. The pioneer nucleic acid researcher, Dr. Benjamin S. Frank studied the beneficial effects of nucleic acids on humans and animals during the 1960s and 70s.

Dr. Frank concluded that dietary nucleic acids are essential nutrients for health. He advised consuming a range of 300–1,500 mg daily. However, he noted that healthy benefits are apparent at levels as low as 75 mg.

Hank Liers, PhD formulated the Rejuvenate! line of superfoods to leverage the powers of dietary nucleic acids for health. These superfood powders are nutrient dense, tasty, easy to consume, portable, and powerfully healthful.

While all Rejuvenate formulas contain dietary nucleic acids from a variety of sources, Rejuvenate! Original and Rejuvenate! PLUS contain chlorella, known to contain the highest levels of nucleic acids among all foods.

Chlorella also provides many benefits beyond nucleic acids. In this article, I will explore chlorella as an important ingredient in Rejuvenate! superfoods, as well as a superfood in its own right.


Chlorella provides more dietary nucleic acids than any other green superfood ingredient.


Chlorella is a single-celled, fresh-water aquatic plant, named so after the Greek word chloros meaning “green”— because it contains large amounts of the green phytonutrient chlorophyll. Millions of people take chlorella every day (many in East Asia) because it is a highly nutritious superfood.

Researchers who’ve studied chlorella extensively say it’s nature’s “perfect food.” In fact, NASA studied it as a food for astronauts. Chlorella provides a broad spectrum of nutrients, including protein, essential fats, fiber, chlorphyll, vitamins, and minerals, including trace minerals.

Chlorella also provides the highest levels of dietary nucleic acids among all foods. Dietary nucleic acids (e.g., RNA) are now recognized as powerful, natural substances that provide supernutrition, rejuvenate, heal, and help create optimal health.


Chlorella can help you look and feel younger. Studies confirm what people taking chlorella have long experienced—the anti-aging effects of dietary nucleic acids on skin, eyes, hair, hands, and other visible parts of the body. Skin typically becomes smoother, tighter, and clearer. Deep lines, wrinkles, and “crow’s feet” are often reduced.

Even acne and foot calluses can clear up as skin becomes softer and healthier. Hair color may return and its texture may become richer and thicker. These changes are more than skin deep. They reflect inner changes created by the nutritional powers of dietary nucleic acids for optimal health.

According to pioneer nucleic-acid researcher Dr. Benjamin S. Frank in Dr. Frank’s No-Aging Diet: Eat and Grow Younger (34), individuals can look and feel five, ten, or even fifteen years younger. That is the little-known power of dietary nucleic acids for health.

Dr. Frank saw those results with his patients consuming dietary nucleic acids (from fish and yeast sources). The anti-aging effects were so evident, he wrote: “It shows on your face.” He saw it happen with nearly all his patients. Dr. Frank emphasizes that such changes in appearance aren’t just “skin-deep” and in fact aren’t even “cosmetic” at all (from a medical standpoint), but stem from deep-down improvements in health (6).

After years of experience with thousands of patients, Dr. Frank concluded that dietary nucleic acids could “revolutionize the appearance of most Americans, because most…are in poor health…aging faster than necessary” (Dr. Frank’s No-Aging Diet, 34). Dr. Frank cared about his patients and knew dietary nucleic acids could help them be healthier.

What Dr. Frank did not know about was chlorella, which is at least 10 times higher in dietary nucleic acids than nutritional yeast or seafoods. If he had known about chlorella, he would have advocated for its consumption to realize the benefits of its dietary nucleic acid content.

Because chlorella is a rich source of nucleic acids, you can expect the type of results reported by Dr. Frank regarding his patients. The benefits of chlorella add up over time—helping people looking and feeling younger—far longer than experienced by those consuming typical (SAD) diets.

In my own experience, I saw myself “growing younger” after consuming chlorella for about three weeks. My rejuvenation hasn’t stopped—I look and feel youthful for my age, and it’s nice having plenty of energy. I’m compelled to share my knowledge about chlorella so other people can benefit from its dietary nucleic acids and other healthy nutrients.

There is a powerful connection between our inner health and outer appearance. When we meet our body’s needs for nutrition and for the energy to carry out its tasks, we can experience glowing health. The dietary nucleic acids in chlorella can help everyone look and feel their very best.


• Heart Health. Chlorella’s nucleic acids help rejuvenate your entire body, including your heart. Chlorella also contains essential fatty acids (i.e., “good” fats), including omega-3 (alpha-linolenic acid). These fatty acids combine with chlorella’s proven ability to lower cholesterol, as well as the rejuvenating and energizing effects of nucleic acids to support excellent cardiovascular health.

In addition, the strengthening and anti-inflammatory actions of polysaccharides, and chlorella’s ability to remove toxic heavy metals play significant roles in reducing the stiffness ness of vessel walls, thereby improving their resiliency and elasticity.

• Breathe Easier. Nucleic acids vastly improve cellular oxygenation and oxygen utilization in the body—enabling far more efficient use of oxygen, including the ability to function better with less. This is a truly remarkable benefit to anyone who wants improved breathing capacity, living in polluted environments or at high altitudes, and for aerobic exercise of any kind.

Studies show nucleic acids dramatically boost exercise performance via increased breathing capacity, greater stamina, and ability to perform physical tasks faster and longer.

Individuals with sufficient dietary nucleic acid intake are less “winded” while walking, running, hiking, swimming, climbing, kayaking, playing tennis, yoga, etc. Even people already in great shape will usually see noticeable differences. For example, gaining greater endurance and reserve capacity. The ability to go farther with less “huffing” or “puffing.”

• Mental Sharpness. The nucleic acids in chlorella greatly improve oxygen utilization, which can greatly improves your mental performance. The capacity of chlorella’s cell wall to help the body eliminate toxic metals (lead, mercury, arsenic, cadmium) also plays a role in increasing mental acuity.

• Blood Sugar Stabilization. Chlorella helps stabilize blood sugar levels by supporting and balancing the liver and pancreas. When these organs do their jobs effectively, blood sugar levels naturally become better balanced. In addition, chlorella can reduce cravings for carbohydrates and sweets.

• Liver Support. Chlorella rejuvenates and cleanses the liver (and other detoxification organs). Nucleic acids directly stimulate cellular repair in liver tissue while improved elimination functions reduce cholesterol and fats in the bloodstream. This helps the liver be more efficient and keep the body healthier.

• Intestinal Health. Supports growth of healthy intestinal flora (“friendly” bacteria) in the digestive tract, aids bowel elimination, and deodorizes.

•Alkalinizing Effects. Chlorella brings balance to body pH by creating alkaline conditions — counteracting the effects of acid-forming foods and substances. This helps create greater health.

• Feel Great. Chlorella’s benefits act synergistically. When all body systems repair and heal, they work better together. Health is more than the absence of disease. When all parts function optimally — in a natural, healthy way — the result is often feeling great due to good health.

Nature has blessed us with chlorella, a superfood with countless health benefits. That is why we include chlorella in Rejuvenate!™ superfoods.

chlorella drink

Consuming a daily green superfood drink with chlorella is a healthy habit.


The ancient Greek philosopher Hippocrates famously exhorted, “Let food be your medicine.” Yet individuals and society don’t always embrace this truth.

Low levels of nutrition offered by the so-called “Standard American Diet” (SAD) are implicated in the rise of degenerative diseases and other conditions of poor health. Ironically, our age is a time of great food abundance and great malnutrition. A time when food quantity often exceeds food quality.

Facing significant declines of nutritional values in modern foods (due to processing, refining, toxic additives, soil degradation, agricultural chemicals, etc.), as well as the nutrient-depletion in our bodies related to factors like high-speed/high stress lifestyles, poor food choices, and lack of education about nutrition, why should a nutritious superfood like chlorella go overlooked?

Times are changing. People increasingly want nutrition facts about healing foods and super nutrition offered by whole foods like chlorella.


Chlorella is often considered “nature’s perfect food” because there’s no single food like it. It offers a unique profile of beneficial nutrients, including:

  • Nucleic Acids, including RNA, DNA, and nucleic acid derivatives — a sort of “fountain of youth” providing energy for your cells.
  • Chlorella Growth Factor (GGF) — health-building nucleotide-peptide complex that boosts immunity and speeds healing.
  • Essential Fatty Acids (omega-3 and omega-6 EFAs) — an excellent source of heart-healthy omega-3 alpha-linolenic acid.
  • Richest Source of Chlorophyll of any plant, 4%–7% or greater. 10 times more chlorophyll than alfalfa. Chlorophyll is an amazing healing phytonutrient that powerfully heals, purifies, cleanses, and detoxifies.
  • High-Quality Plant Protein (62% or more) — vegetable protein that’s easy to digest and assimilate.
  • Antioxidants, Enzymes, and Phytonutrients, including naturally occurring beta-carotene and lutein.
  • Vitamins, including vitamins A, C, D, E, and K1; all major B vitamins, and vitamin B12.
  • Minerals and Trace Elements, including iron, calcium, potassium, phosphorus, magnesium, iodine, zinc, manganese, and others.
  • Polysaccharides — protecting your vascular system, strengthening connective tissues, and building immunity (by stimulating interferon production).
  • Fiber (11% insoluble) — promoting heart health, detoxification, easier elimination, and appetite control.

These are some of the nutrients chlorella provides. Let me tell you a little more about chlorella’s dietary nucleic acids because they are responsible for many of the benefits of chlorella.


While chlorella contains many valuable nutrients, one group of nutrients stands out as exceptional: its high content of nucleic acids. In particular, RNA (ribonucleic acid) and DNA (deoxyribonucleic acid).

Nucleic acids are involved in many bodily processes, especially energy production and communication within cells (i.e., they enable cells to use energy effectively for greater health). In the cell nucleus, RNA carries out instructions coded in DNA—instructions containing information critical for cell structure and function—which are essential for the lives of our cells.

When our cells receive proper directions and energy to carry them out, they have the resources to help keep us youthful, or at least not age prematurely. Chlorella’s nucleic acids provide us basic materials for repairing and replacing our RNA and DNA, thereby giving us potentially greater energy, vitality, and longevity.

Our bodies naturally make nucleic acids. However, with increasing age we gradually lose our capacity for synthesizing them. This is where nucleic acids from foods can make a difference for health. As noted, pioneer RNA researcher Dr. Benjamin S. Frank discovered that dietary nucleic acids not only improve health, but also slow down and even reverse the aging process.

Many decades of research led Dr. Frank to conclude that nucleic acids are not only improve health, but they’re actually “essential nutrients.” In particular, he describes RNA as “the anti-aging factor.” His research laid the foundation for understanding the effects of all high-nucleic acid foods, including chlorella.

In his books, Dr. Frank predicts nucleic acids will be the “medicine” of the future, but says that everyone can benefit right now — by eating high-nucleic acid foods. In fact, his best-seller Dr. Frank’s No-Aging Diet is a guide for helping people learn about consuming foods high in nucleic acids for optimal health. Yet, he’s hardly alone in his enthusiasm for nucleic acids from foods.

Dr. Frank has plenty of company in his praise for dietary nucleic acids. In a classic, groundbreaking book titled Chlorella, Jewel of the Far East, natural healer Dr. Bernard Jensen focuses on the health benefits of chlorella and its nucleic acids.

Dr. Jensen states, “Eating foods high in nucleic acids provide the material for the repair and production of human nucleic acids…the breakdown of DNA and RNA in the cells [is]…one of the main factors in aging and in degenerative diseases” (83).

He spent his life traveling the world searching for secrets of health and longevity. He was impressed by the “mind blowing” effects of dietary nucleic acids on human health, especially the effects of chlorella.

Dr. Jensen marveled at chlorella’s nutritional characteristics. He understood then that it would take time to study and understand the mechanisms behind chlorella’s evident benefits. However, he was clear in stating that while science takes time unraveling chlorella’s mysteries, anyone can benefit from consuming it right now—without waiting for the day when modern science fully reveals how it makes us healthier.

He also states, “We know from studies, from experiments and the experiences of many people that chlorella protects the body and restores health, without undesirable side effects” (85).

Nutrition science already reveals the foods highest in nucleic acids. These foods include fish, organ meats, beans, brewer’s yeast, and most of all chlorella. Yet, foods and superfoods aren’t typically promoted for their high nucleic acid levels. Most doctors and nutritionists know little about the importance of dietary nucleic acids.

Yet, nothing prevents individuals from consuming high-nucleic acid foods right now, as Dr. Frank and Dr. Jensen advise.


Chlorella’s nucleic acids help you become healthier. Studies prove the remarkable powers of nucleic acids to heal, rejuvenate, rebuild, restore, improve quality of life, and even prolong life.

Nucleic acids are known to increase energy levels and cellular oxygenation, boost physical stamina and lung power, and augment overall health and well being. They also smooth skin, reduce wrinkles, increase lean muscle mass, lower cholesterol, support cardiovascular health, aid metabolism, stabilize blood sugar, and even help regulate body temperature (for example, they can increase body warmth for greater comfort in cold climates).


One essential fact you need to know about chlorella’s nucleic acids is that they dramatically increase energy. Nucleic acids boost energy levels in the body by significantly increasing production of the “high-energy” molecule ATP (adenosine triphosphate), and thereby retard the aging process.

Our bodies use ATP in many ways. For example, cell repair, healing, metabolism, digestion, supporting the immune system, and other processes. This means chlorella is a total body healing food and a systemic healer that rejuvenates deeply from the cellular level on up, and from the inside out.

Our bodies know exactly how to use dietary nucleic acids to make energy to satisfy our needs. In this sense, RNA acts as a “smart” nutrient providing energy wherever we need it most, and thereby functions as an “adaptogen.” Precisely because dietary nucleic acids support metabolism and slow aging, many nutrition scientists consider chlorella among the top superfoods in the world.


Chlorella offers more than an incredibly high nucleic acid content. The 5% nucleic-acid rich fraction of chlorella contains a substance known as “Chlorella Growth Factor” or CGF.

First isolated by Japanese scientists in the mid-1950s, Chlorella Growth Factor is a nucleotide-peptide complex containing nucleic acids and nucleic-acid derivatives, like amino acids, peptides, nucleotides, nucleosides, polysaccharides, beta-glucans, and other beneficial substances. Most importantly, it’s natural, safe, and demonstrates potent healing powers.

CGF is best known for having powerful growth stimulating properties. In fact, in Japan it’s used to boost growth in children with growth disorders.

CGF doesn’t boost growth in adults, but instead enhances immune system response, repairs nerve tissues (e.g., especially helpful for brain and nerve disorders), and works powerfully to speed healing. Also, the body uses this growth factor to produce energy in support of metabolic processes and to revitalize cellular functioning.

Because CGF is a concentrated source of nucleic acids (RNA and DNA), its constituents act synergistically to provide you with superb nutrition for optimal health.

CGF offers potent health benefits like immune support, rapid healing, regeneration, and rejuvenation. Thus, Chlorella Growth Factor is another reason why chlorella is one of most complete superfoods on the planet.


Chlorella’s energizing and healing powers are remarkable. Its nucleic acids and Chlorella Growth Factor support optimal health. Yet, chlorella also contains vast quantities of chlorophyll, the green phytonutrient found in all plants. As a superfood that gets its name from chlorophyll, chlorella’s chlorophyll content is extremely high—4% to 7%, or greater. That’s the highest chlorophyll content of any plant. Chlorophyll itself is a significant healing substance.


Chlorophyll has many proven benefits: it cleanses, deodorizes, disinfects, detoxifies, alkalinizes your body, and speeds healing (internally and externally). It has been said, “If you’re green inside, you’re clean inside.” And due to chlorophyll’s structural similarity to human blood cells, consuming it builds a high blood count.

Here’s a partial list of chlorophyll’s benefits:

• Detoxifies, deodorizes, cleanses, and purifies. Chlorophyll is nature’s greatest purifier.

• Removes heavy metals from the body, including mercury, lead, arsenic, cadmium, aluminum, and other toxic metals (see Mike Adams’s Superfoods for Optimum Health, www.chlorellafactor.com 10)

Due to industrialization, polluted water, dental amalgams, and consumption of predatory fish (high in mercury), it is estimated that most Americans have relatively high levels of toxic metals in their bodies. Chlorophyll helps reduce the burden of metals on the body.

• Removes pesticides, polychlorinated biphenyls (PCBs), dioxins, and industrial chemicals.

• Aids liver function—via purification and detoxification, and supports other elimination functions in the body! (see Mike Adam’s Superfoods for Optimum Health, www.chlorellafactor.com 10)

• Can reduce pain in certain instances (see Dr. Bernard Jensen’s The Healing Power of Chlorophyll, 105.)

• Builds a high blood count and  thereby can improve anemia due to chlorophyll’s structural similarity to human blood cells. (See Dr. Bernard Jensen’s The Healing Power of Chlorophyll, 105).

Chlorophyll is a powerful healer. People take everything from parsley extracts to wheatgrass juice to obtain its benefits. But chlorella contains far more chlorophyll than these sources and provides many other health-building elements–as discussed above—a winning combination for good health.


Few foods offer as many benefits for health as chlorella. Providing dietary nucleic acids, Chlorella Growth Factor (CGF), chlorophyll, protein, vitamins, minerals, essential fats (omega-3 and omega-6), antioxidants, polysaccharides, phytonutrients, and fiber, chlorella is an ideal ingredient to include in superfood formulas. Thus, chlorella provides users with high levels dietary nucleic acids and many other healthful nutrients that work synergistically to support optimal health.


Hank Liers, PhD formulated Rejuvenate! superfoods specifically to provide high levels of dietary nucleic acids. Chlorella is one of several significant sources of the dietary nucleic acids in HPDI’s Rejuvenate! Original and Rejuvenate PLUS. Note: Rejuvenate! Berries & Herbs contains no chlorella (or any greens), but still provides therapeutic levels of nucleic acids.

Chlorella is a champion ingredient among high-RNA ingredients. Individuals interested in optimal health should consider chlorella and superfoods high in chlorella as allies providing the highest levels of dietary nucleic acids and nutrients supporting their use in the body.



Fred Liers PhD riboseAvoiding excess dietary sugars is one of the healthiest things. But there is one sugar that really is good for you. That sugar is D-ribose.

In fact, D-ribose is so healthy for you, it may be the one sugar you won’t want to live without. A little background to this amazing sugar.

D-ribose is a 5-carbon monosaccharide occurring naturally in living cells. D-ribose importantly forms the carbohydrate parts of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). That means d-ribose is the sugar essential for the biological function of all living creatures, including humans.

Supplemental D-ribose is associated with many benefits. These benefits include greater energy, less fatigue, and faster muscle recovery. These benefits relate to the capacities of D-ribose as a total body energizer because it boosts energy production (as ATP) in the body.

For individuals suffering low energy levels associated with chronic fatigue syndrome (CFS), low energy levels, and other problems related to low energy (ATP) production, D-ribose can mean a significantly higher level of energy. In cases of extremely low energy, it can mean the capacity to function more normally.

ribose energy woman power health

D-ribose energizes every cell in our bodies.

Athletes and bodybuilders were among the earliest to recognize D-ribose for purposes of improving performance and recovery times. D-Ribose also exerts anti-anxiety, stress reduction, and potential anti-depressant properties. There is additional evidence suggesting that supraphysiological amounts of ribose may have cardioprotective effects, especially for the ischemic heart.

Supplemental D-ribose usually comes in the form of a sweet, crystalline, water-soluble powder. It is also available in capsules or tablets, including chewable tablets.

Humans synthesize d-ribose from foods, including glucose and various dietary sugars. But there are benefits to supplemental D-ribose. One of the major reasons is the important role of D-ribose in the production of energy (ATP) in human cells.













ribose sugar natural heart energy ATP RNA

D-ribose is heart healthy unlike most dietary sugars (e.g., sucrose).


The body uses D-ribose to generate adenosine triphosphate (ATP).  ATP provides energy for all bodily movements and every chemical reaction in cells. ATP is the source of all energy in the body and it’s constantly broken down and recreated due to the processes of life.

The adenine portion of ATP consists of one molecule of adenine and ribose (i.e., five-carbon sugar). The triphosphate portion of ATP consists of three phosphate molecules. When a phosphate breaks off from ATP, then energy is released. The compound then becomes adenosine diphosphate (ADP), which consists of adenosine and two phosphate molecules. When another phosphate molecule breaks off, it becomes adenosine monophosphate (AMP).

It is well established that ratios of ATP, ADP, and AMP are essential for regulating energy in cells. Under extreme physiological stress (e.g., high-intensity exercise), our cells cannot recreate ATP rapidly enough to supply cells with required energy. Concentrations of ADP and AMP rise causing a reduction in cellular energy. When the body’s rate of ATP use continues exceeding the rate at which it can be generated, cells “lose” nucleotides in order to restore the ratio between ATP, ADP, and AMP.

During anaerobic metabolism, AMP levels can rise within cells, thereby disturbing the ratios of ATP to ADP and AMP. The body can reduce AMP concentrations by degrading AMP to simpler end products resulting in a significant decrease in the adenine nucleotide pool. Under extreme conditions (e.g., prolonged high-intensity exercise or the diminished blood flow to tissues witnessed in ischemia), the adenine nucleotide pool may decrease by 30–50%. These effects can significantly compromise physical performance.

Here is where D-ribose supplementation works to support energy production. Supplemental D-ribose allows the body to bypass relatively slow conversion steps required for recreating the adenosine nucleotide providing critical material for ATP production. That is, D-ribose can increase the speed of nucleotide replacement. This has implications not only for sports performance, but also for general health. D-ribose is especially useful in situations where greater energy may be required, as in low energy, chronic fatigue, fibromyalgia, or combating the effects of aging.


One of the most important aspects of D-ribose for health relates to the fact that it is the rate-limiting compound that regulates the activity of the purine nucleotide pathway of adenine nucleotide metabolism. As such, ribose plays a central role not only in the synthesis of ATP, but also of coenzyme-A, flavin adenine dinucleotide (FAD), nicotinamide adenine dinucleotide (NAD), DNA, RNA, and other important cellular constituents.

In fact, D-ribose is the only known compound the body can use for performing this critical metabolic function. Specifically, ribose administration bypasses the slow and rate-limited pentose phosphate pathway to stimulate adenine nucleotide synthesis and salvage in vivo. In addition, it has been shown that de novo adenine nucleotide synthesis in skeletal muscle is rate limited by the availability of ribose.

Specifically, human muscle cells (e.g., heart and skeletal muscle cells) do not rapidly replace lost nucleotides because of the lack of two rate-limiting enzymes in the pentose phosphate pathway metabolizing glucose to ribose-5-phosphate. Ribose itself forms 5-phosphoribosyl-1-pyrophosphate, a rate-limiting compound in nucleotide synthesis. As noted, supplemental D-ribose allow the body to bypass the rate-limited steps of the pentose phosphate pathway, thereby accelerating nucleotide synthesis (and salvage).


It should not take a genius to figure out that when energy production is optimized, overall health will improve. Yet, the same principle also applies in reverse. That is, there are many instances in which low energy levels can fuel lower energy levels. For example, when illness, stressors, or other factors deplete large amounts of the body’s supply of energy, they can gradually (or not so gradually) lessen the body’s capacity to produce more by overtaxing the energy production system.

This cascade of reduced energy production can become a vicious cycle in which there are few reserves left to support the body’s need for greater energy. D-Ribose is one of the only nutrients that can reverse the downward spiral in ATP production when demands exceed supply. By feeding the body’s own system for producing energy, and thereby supplying the raw material required to produce it, supplemental D-ribose can helps break the cycle of low energy levels.

fatigue ribose natural sugar energy atp cells

Chronic low energy? D-ribose is required for creating energy for all biological functions.


To recap the importance of supplemental D-ribose: D-ribose increases the rate at which ATP is generated. This improves exercise performance and allows for faster muscle growth. All this is possible because supplemental ribose helps the body bypass the conversion steps needed to create or re-create adenosine nucleotides.

Because replacing adenine nucleotides normally requires a certain amount of time, providing the body with D-ribose supplementally via diet can reduce rates of healing and repair in muscle cells. That is, supplemental D-ribose can increase the speed at which adenosine nucleotides are replaced by providing raw material for the creation of more ATP. That is how D-ribose improves athletic performance and supports optimal energy production, as well as optimal muscle health.

The significance of the science behind ATP production is that almost everyone can benefit from supplemental D-ribose. Whether you are an athlete requiring rapid repletion of energy, a person suffering from low energy levels or chronic fatigue, or anyone who wishes to improve energy production supporting optimal health.

ribose energizes beautiful athletic girl with colorful balloons jumping on the beach

Fatigued to fantastic: a plentiful supply of D-ribose helps ensure an abundance of energy.


We at HPDI have focused our efforts on formulating the most effective nutritional supplements and superfoods. When Dr. Hank Liers formulated our original high-RNA Rejuvenate! superfood, he put D-ribose into it. In fact, all of our Rejuvenate! superfoods provide significant amounts of D-ribose.

Rejuvenate! (original greens) provides 1,500 mg D-ribose per serving (one small scoop). Rejuvenate! PLUS provides 1,800 mg per serving (two scoops). Rejuvenate! Berries & Herbs provides 2,000 mg per serving (two scoops).

ribose energy dietary nucleic acids rejuvenate superfoods

All Rejuvenate! superfoods provide high levels of D-Ribose.

A major reason HPDI includes D-ribose in its superfoods–and perhaps the most obvious one–is simply that we formulate unique, high-RNA superfoods to support optimal energy production in the body. D-ribose supports that goal by various means.

D-ribose is the rate-limiting sugar for the uptake and assimilation of dietary nucleic acids (RNA, DNA, nucleotides, and nucleosides). This is because D-ribose is actually the sugar backbone of these nutrients. As such, the body requires D-ribose in order to utilize and create (or recreate) dietary nucleic acids.

For example, nucleotides are the molecular building blocks of DNA and RNA. They are chemical compounds consisting of a heterocyclic base, a 5-carbon sugar (ribose or deoxyribose) and at least one phosphate group. They are the monomers of nucleic acids, and 3 or more can bond together to form a nucleic acid.

Nucleosides are glycosylamines consisting of a base (or nucleobase) to a ribose (or deoxyribose) ring. Some nucleosides are cytidine, adenosine, guanosine, and inosine. When nucleosides are phosphorylated in cells, they produce nucleotides (see above).

Thus, D-ribose plays important roles as an essential part of nucleic acids, nucleotides, and nucleosides; in the production of energy (as ATP); and the synthesis and salvage of nucleotides in the body.

Rejuvenate! superfoods are formulated to provide high levels of nucleic acids. D-ribose helps the body optimize its use of nucleic acids and their constituent components. Having D-ribose in our superfoods not only supports energy production directly, but also allows maximum use of the dietary RNA they are formulated to provide.

Rejuvenate! superfoods provide nutrients that boost energy levels significantly and consistently for optimal health, healing, and wellness. The inclusion of D-ribose importantly supports the powerful nucleic acid nutrition these superfoods offer, as well as supplements the body’s intake and synthesis of D-ribose.

ribose energy rejuvenate plus (500g) RNA nucleic acids doctor hank liers original

REJUVENATE! PLUS provides 1,800 mg of D-ribose per serving.


D-Ribose of one of the most important natural sugars for life and health. It is one of the few nutrients that can boost energy levels naturally. When taken with other important biological nutrients, including dietary RNA, DNA, nucleotides, and nucleosides, D-ribose is truly a nutritional powerhouse that can support good health and the energy levels required to live life to its fullest. We believe the best way to obtain supplemental D-ribose is to consume Rejuvenate! superfoods.












Pentose-Phosphate Pathway: Elsevier’s Review of Biochemistry

From Fatigued to Fantastic (excerpt) by Jacob Teitelbaum, MD

D-Ribose technical information (Vista Chemicals)

Enhancing Cardiac Energy with Ribose (LEF)


The Use of D-Ribose in Chronic fatigue syndrome and fibromyalgia (J Altern Complement Med.)

D-Ribose Aids Advanced Ischemic Heart Failure Patients (Int J Cardiol.)

D-Ribose, a Metabolic Substrate for Congestive Heart Failure (Prog Cardiovasc Nurs.)

D-Ribose as a Supplement for Cardiac Energy Metabolism (J Cardiovasc Pharmacol Ther.)

Ribose Accelerates the Repletion of the ATP Pool During Recovery from Reversible Ischemia of the Rat Myocardium (J Mol Cell Cardiol.)

Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats (Cardiovasc Drugs Ther.)

Stimulation of Myocardial Adenine Nucleotide Biosynthesis by Pentoses and Pentitols (Pflugers Arch.)

The Role of Ribose on Oxidative Stress During Hypoxic Exercise (J. Med. Food)

D-Ribose Benefits Restless Legs Syndrome (J Altern Complement Med.)



Fred Liers PhD rejuvenate smoothie irena ossola

HPDI’s sponsored women’s pro elite cyclist Irena Ossola is busy all summer racing, including multiple top 10 finishes at the Prairie State Cycling Series this week in the Chicago region. Irena raced in June with Team Cloud in Minnesota and Wisconsin. In May, she competed in the US Elite Pro Nationals in Chattanooga, Tennessee.

Yet, Irena hasn’t been too busy to keep up her nutrition program, take HPDI foundational supplements, or make smoothies with Rejuvenate!™ superfoods. Just the opposite. Time spent competing in top-level races and traveling widely means keeping up intake of important nutrients for high performance.

This month Irena offers up a recipe for one of her favorite Rejuvenate! smoothies, and a few choice words about how she creates it.

As an elite athlete, Irena places great demands upon her body and mind that most people cannot too readily imagine. When HPDI began sponsoring her in March, it was because it was a good fit for her and us. Irena had already tried Rejuvenate! superfoods on her own finding they improved her recovery times. Rejuvenate! superfoods provide dietary nucleic acids (like RNA and DNA), which support optimal athletic performance, recovery, well-being, and health.

Irena Ossola rejuvenate smoothie

Irena’s busy race schedule means greater needs for superior nutrition.

Indeed, Irena requires superior products supporting her nutritional needs as she requires super-nutrition for training and racing. In return, we get to test our advanced formulas on a working pro athlete whose performance and progress give us ideas about making our products and rejuvenation program better. And how best to incorporate our products into complete programs for athletic performance and improved results for athletes in all sports.

HPDI nutritional supplements Irena uses include: Multi Two Tabs (multivitamin), Ultimate Protector (Nrf2 activator formula), Myo-Mag (magnesium formula), Omega Plus (essential fatty acids formula), Rejuvenate! Berries & Herbs, Rejuvenate Plus, and Rejuvenate! (original greens). That is, she incorporates both foundational supplements and other advanced HPDI formulas in a complete supplement program supporting her needs for optimal nutrition.

We at HPDI hope you enjoy Irena Ossola’s Rejuvenate! smoothie recipe. We encourage you to try it. Maybe you will improve your performance whether you cycle, run, swim, hike, walk, or just live life to its fullest!! Tell us how you like it!! ~



• FROZEN FRUIT: Strawberries, Pineapple, Blueberries, and Raspberries and/or Blackberries (As Desired)

• BANANA (One Or Part) (Optional)

• COCONUT FLAKES (Dried, Unsweetened) (To Taste)

• GREENS: SPINACH AND/OR KALE Leaves (1–2 Handfulls)

• FLAX SEEDS: 1–2 Teaspoons (or 1 Scoop)

• CHIA SEEDS: 1–2 Teaspoons (or 1 Scoop)

• REJUVENATE!™ SUPERFOODS (PLUS, BERRIES & HERBS and/or Original): 1–2 Scoops



• YOGURT (As Desired)

• ICE (As Desired)


Mix all ingredients in a blender. Then serve and enjoy!!


“As a full time athlete I train every day and sometimes multiple times a day. To keep in top form and fuel myself to sustain high energy and perform well, it is important that I maintain a healthy diet and provide my body with the proper recovery after every training session or race.

Whether or not you are an athlete in training, or using HPDI’s Rejuvenate! superfoods to feel better and fuel your body, my smoothie recipe combines the proper ingredients for your health and it tastes great!!

I mix in a combination of these ingredients (above) and adjust them to taste depending on availability of ingredients and desire for variety.

If the smoothie tastes too ‘green’ for you, then I suggest adding more banana as it will sweeten things.

If you like berries in your smoothies, yet also wish to reduce sugars, then try eliminating the banana.

I love adding protein powder to a smoothie. The protein adds a smoothness and lessens the icy texture from ice or frozen fruit. Chia seeds and flax seeds add a solid, filling consistency and they are really good for recovery.

I tend to use unsweetened almond milk (instead of milk or soy milk) because it usually has higher levels of protein and essential fats.”


rejuvenate smoothie

Rejuvenate! superfoods are foundational elements of my nutrition program & Rejuvenate smoothies.


rejuvenate smoothie superfoods

Be creative with ingredients when you make Rejuvenate smoothies.



Any blender will do. In seconds you’ll have my Rejuvenate! smoothie.


rejuvenate smoothie strawberry plus berries herbs drink

Rejuvenate smoothie ready to drink!!



Bearing down at Nationals Time Trial in Chattanooga, TN. I’m powered by Rejuvenate! superfoods.