0

EXCITING NEW TERRAFLORA SYNBIOTIC

Terraflora Synbiotic

Dr. Hank Liers, PhD Terraflora synbioticIt has finally arrived — the exciting new Terraflora™ synbiotic. A synbiotic is a combination of probiotics and supporting prebiotics. This advanced soil-based organisms formula fills the need for a superb probiotic/prebiotic in Health Products Distributors’ arsenal of highly effective formulas. Terraflora is extremely supportive of your entire microbiome and gut-based immune system.

 

ADVANCED GUT MICROBIOME SUPPORT

INTRODUCING THE MICROBIOME

For centuries, scientists have recognized a limited number of pathogenic bacteria for which antibiotic therapies have become the mainstream treatment. However, advanced DNA sequencing techniques coupled with data revealed from the Human Genome Project have made it possible to study a vast world of ‘germs’ – both pathogenic and beneficial – that dwarf our previous knowledge.

While we inherit more than 22,000 genes from our parents, the bacteria that exist in and on our bodies contain at least eight million bacterial genes which amounts to 360 times more bacterial genes than human genes! The genetic material from bacteria that populate the human body is known as the human microbiome.

Your microbiome is likely similar to that of your immediate family, as we naturally inherit our family’s microbiota. Through the course of our lives, we pick up other bacteria from food, water, and various components of our environment. Scientists estimate that we each carry 100 trillion bacteria in our intestinal tract alone!

In this teeming landscape of bacteria, both you and the bacterial communities derive benefit. Many researchers use the term “mutually beneficial” when describing the evolving bacterial communities in our gut.

THE BALANCE OF BACTERIA AND YOUR HEALTH

In 2010, the Human Microbiome Project published an analysis of 178 genomes from bacteria that live in or on the human body. 10,000 different types of bacteria in the human body have been identified, including novel genes and proteins that serve functions in human health and disease. The vast numbers of bacteria discovered appear to provide benefit to the human body, not harm.

Martin J. Blaser, chairman of the Department of Medicine and a professor of microbiology at the New York University School of Medicine states: Germs make us sick, but everyone focuses on the harm. It’s not that simple, because without most of these organisms we could never survive.

As scientists map the human microbiome, they are beginning to understand the difference between normal and abnormal. Proper bacterial balance is vital to healthy immune function, providing appropriate protection against potential infections, playing a critical role in the digestion and absorption of food and nutrients, and even regulating mood. The interaction of multiple strains of bacteria is an essential element in health and wellbeing.

The optimal balance of bacteria can be altered in many ways such as broad spectrum antibiotics that kill bacteria in the gut indiscriminately; prescription medications; disease-carrying bacteria, fungi, parasites, and yeasts; stress; lack of sleep; poor diet & lifestyle; geography and travel; and physical disconnection with nature.

Researchers have shown that changes in gut bacteria even affect the brain and personality. For example, germ-free mice have been shown to be dramatically more anxious and hyperactive than their counterparts with a normal microbiome. These changes have also been associated with neurochemical changes in the mouse brain.

Evidence supports the concept that microbiota balance can have a large impact on healthy metabolic processes. This delicate balance has a definite impact on nutrient acquisition and overall energy regulation.

The impact of the gut microbiota is far reaching in the body. Continued investigation into the microbiome will yield powerful data, enabling the development of novel options to support healthy mood, metabolism, signaling molecules and much more.

Terraflora

FEATURES OF TERRAFLORA

Terraflora is a novel broad spectrum synbiotic formulated with a combination of spore form probiotics, and advanced, food-based, ancient prebiotics designed for robust support of gastrointestinal health.

  • Innovative gut microbiome support
  • Multi-strain, soil-based, beneficial bacteria to support microbial diversity in the GI tract
  • Proprietary blend of ancient, wild-harvested, certified organic prebiotic support
  • Terraflora’s advanced formulation of beneficial strains and ancient prebiotics are designed to support the biodiversity reflected in ancestral diets
  • Shelf stable and requires no refrigeration
  • Highly bioavailable strains are protected by a natural seed-like structure, guarding against environmental factors and stomach acid
  • Strains effectively generate highly bioavailable riboflavin (vitamin B2) and antioxidant carotenoids, right at the sight of absorption
  • Induces anti-inflammatory effects to foster gut homeostasis
  • Supports immune health

TERRAFLORA KEY BENEFITS

VIABILITY – The natural seed-like structure encasing the probiotc bacteria in Terraflora protects them against degradation by stomach acid, so they reach their target destination — the lower GI tract — intact and alive.

ADVANCED PREBIOTIC SUPPORT – Uniquely formulated with organic seaweeds (see reference 2 below), mushroom extracts (see reference 1 below), and humic acid (see reference 3 below). Terraflora’s advanced prebiotic complex contains a diverse spectrum of naturally occurring food-based polyphenols and polysaccharides designed to support healthy intestinal flora

ANTIOXIDANT BENEFITS – Terraflora features Ribospore™ (Bacillus pumilus) and Bacillus megaterium EM144™, two novel probiotic strains shown in studies to produce highly bioavailable, gastric stable antioxidant carotenoids, right at the site of absorption.

CONVENIENT — NO REFRIGERATION REQUIRED! – To ensure potency and viability, most probiotics require refrigeration and have a short shelf life. The inherently resilient bacteria in Terraflora are heat-stable, and require no refrigeration, uniting convenience and efficacy.

WHY SOIL-BASED ORGANISMS?

Through diet and lifestyle, our earliest ancestors were routinely exposed to spore-based bacteria found in healthy soils and our natural environment. In our modern and hyper-sanitized world, this primitive yet vital connection to nature has been all but lost.

Soil-based organisms (SBOs) define a class of probiotic supplements based on a greater understanding of the incredible diversity of the human gut, coupled with a deeper appreciation for how humans and their commensal “helper” bacteria work together to produce a healthy system.

Soil-based bacteria have a three-stage life cycle, with each stage triggered by nutrient availability: vegetative growth, sporulation, and germination. The sporulation phase is particularly relevant to its potential as a probiotic. The spore structure preserves the bacteria in a dormant phase and against any harm whether in any terrestrial environment or in the acidic environments of the stomach and upper intestines. When these probiotic microbiota are ingested, they travel all the way to the lower intestine where they come alive. Like a seed, warm temperatures, moisture, and nutrients stimulate the germination stage where bacteria emerges from dormancy. Soil-based probiotics are well-adapted to the environment of the gut, and have been shown to remain in the digestive tract where they can provide long term benefit.

SBO probiotics are characterized by two traits that make them superior to other probiotics: 1) the spore phase enabling natural resistance to the harsh environment of the upper digestive tract and stomach, and 2) inherent environmental stability that does not require the addition of specialized coatings or preservatives to ensure a clinically relevant amount reaches the appropriate areas of the gut.

Though SBO probiotics are based directly on symbiotic communities of bacteria found in natural soil environments, these organisms are not harvested directly from the earth to be packaged as a supplement. They are instead produced in a safe, monitored environment to ensure specificity of the strains.

Why are soil-based probiotics so popular among clinicians, and what makes them so important?  The answer to this question lies in an understanding of the human gut microbiome.

MULTI-STRAIN BACILLUS COMPLEX

Bacteria are incredibly ubiquitous, highly adaptable ancient life forms that evolved relatively unchanged over nearly 4 billion years. Bacillus, in particular, is arguably Earth’s most resilient bacteria―the oldest of which having been cultured and identified from the abdominal contents of extinct bees preserved in amber for 25 to 40 million years.

Through diet and lifestyle, our earliest ancestors were routinely exposed to bacillus spores found in healthy soils and our natural environment. Yet we no longer have routine exposure to bacillus spores due to the hyper-sanitization of our post-industrial civilization. Terraflora’s unique probiotic + prebiotic bio-complex of commensal bacillus strains reconnect humans with their ancestral environment.

Terraflora bridges the lost connection to our natural environment, with a sophisticated probiotic bio-complex of specific, commensal Bacillus strains. Selected for their unique characteristics, Bacillus are gram-positive bacteria that can exist in two forms. Under favorable conditions the bacteria grow in a vegetative form, but when starved of nutrients they differentiate into a dormant life form known as an “endospore” or simply a “spore”. These spores come alive when introduced to an ideal environment, like the human gut.

Terraflora’s innovative DNA verified strain combination introduces Ribospore™ (Bacillus pumilus) and Bacillus megaterium EM144™, microorganisms scientifically proven to effectively produce highly bioavailable antioxidants and riboflavin, right at the site of absorption. Riboflavin is an essential nutrient for maintaining a healthy digestive tract.

In addition to our proprietary new RibosporeTM (Bacillus pumilus) and Bacillus Megaterium EM144TM—Bacillus subtilis, Bacillus clausii, and Bacillus coagulans complete Terraflora’s multi-strain probiotic bio-complex.

ADVANCED PREBIOTIC BIO-COMPLEX


Terraflora™ contains a prebiotic blend of certified organic, wild-harvested seaweeds, mushroom extracts, and humic acid. These ancient, food-based prebiotics support commensal microbiota with a diverse spectrum of naturally-occurring polyphenols and polysaccharides designed to strengthen healthy intestinal flora. This bio-complex includes:

LARCH ARABINOGALACTAN: A solvent-free water extract that retains all bioactive polyphenolic flavonoids present in Larch, including taxifolin and quercetin. Larch arabinogalactan is a densely branched, non-starch polysaccharide consisting of galactose and arabinose molecules. It has been shown to increase production of critical short-chain fatty acids (SCFAs) such as butyrate in the gut. Butyrate is the principle fuel for intestinal cells and supports healthy tight junctions in the gut lining. In addition, Larch arabinogalactan enhances beneficial gut flora and increases levels of beneficial intestinal anaerobes, particularly Bifidobacterium longum.

FUCUS VESICULOSUS (BLADDERWRACK) & UNDARIA PINNATIFIDA (WAKAME) EXTRACTS: These are certified organic solvent-free water extracts that are wild-harvested from clean ocean waters of Patagonia and Nova Scotia. They are rich in marine polyphenols and complex, sulfated, fucose-rich polysaccharides called fucoidans. Fucoidans are found in edible brown seaweeds and are shown to have multiple bioactivities including the support of healthy inflammation response in the GI tract. In vitro studies show that fucoidan effectively inhibits adhesion of pathogenic bacteria Helicobacter pylori and Escherichia coli to human cells. Furthermore, they increase the abundance of beneficial bacteria and significantly decrease inflammatory response and antigen load of the gut microbiota. In addition, they may also help maintain levels of beneficial bacteria in the gut during antibiotic use and are known to increases the integrity of tight junctions in the gut lining.

NORDIC CHAGA EXTRACT: This ingredient is a certified organic hot-water extract obtained exclusively from the mushroom fruiting body. It is sustainably wild-harvested in the Arctic (Finnish Lapland forest) and contains a diverse spectrum of polysaccharides and polyphenols. This extract has been shown to help protect against acute colonic inflammation and shown to decrease the Firmicutes-to-Bacteroidetes bacterial ratios. Decreased Firmicutes-to-Bacteroidetes ratios are significantly associated with lower body mass index (BMI).

RED REISHI EXTRACT: A certified organic extract obtained by traditional hot-water extraction methods exclusively from the mushroom fruiting body. It contains a diverse spectrum of polysaccharides and polyphenols that have been shown to increase microbiota richness and regulate intestinal barrier function. It is known to support the health of the gut lumen. Furthermore, is has been shown to decrease Firmicutes-to-Bacteroidetes ratios and endotoxin-bearing Proteobacteria levels.

HUMIC ACID: The humic acid in Terraflora is water extracted from ancient freshwater humate deposits. It has been shown to significantly increase the overall concentration of colonic microbiota.

TERRAFLORA INGREDIENTS

Probiotic Bio-Complex: 1 Billion Viable Cells per serving
Ribosporea  (Bacillus pumilus)
Bacillus megaterium EM144a
Bacillus subtilis
Bacillus clausii
Bacillus coagulans


Prebiotic Bio-Complex: 850 mg per serving
Larch Arabinogalactan (Larix spp.), Reishi (Ganoderma lucidum) Extract (fruiting body), Wild-Harvested Chaga (Inonotus obliquus) Extract (fruiting body), Wild-Harvested Nova Scotian Bladderwrack (Fucus vesiculosus) Extract (thallus), Wild-Harvested Patagonian Wakame (Undaria pinnatifida) Extract (sporophyll), and Humic Acids.

Other Ingredients: Plant cellulose (veggie capsule)

Contains No: dairy, wheat, yeast, gluten, corn, sugar, soy, shellfish, tree nuts, or GMOs. Made without stearates, fillers, binders, flow agents, or additives of any kind.

DIRECTIONS

Serving Size: Two Veggie Capsules            Servings Per Container: 30

Suggested Use: Take 1–2 capsules per day with or without food, or as recommended by your health care professional.

If you are pregnant, nursing, or have a medical condition, consult your healthcare practitioner before use.

REFERENCES

  1. Paper regarding the use of mushroom extracts as prebiotics:

    A Critical Review on Health Promoting Benefits of Edible Mushrooms through Gut Microbiota
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618583/

    Abstract
    Mushrooms have long been used for medicinal and food purposes for over a thousand years, but a complete elucidation of the health-promoting properties of mushrooms through regulating gut microbiota has not yet been fully exploited. Mushrooms comprise a vast, and yet largely untapped, source of powerful new pharmaceutical substances. Mushrooms have been used in health care for treating simple and common diseases, like skin diseases and pandemic diseases like AIDS. This review is aimed at accumulating the health-promoting benefits of edible mushrooms through gut microbiota. Mushrooms are proven to possess anti-allergic, anti-cholesterol, anti-tumor, and anti-cancer properties. Mushrooms are rich in carbohydrates, like chitin, hemicellulose, β and α-glucans, mannans, xylans, and galactans, which make them the right choice for prebiotics. Mushrooms act as a prebiotics to stimulate the growth of gut microbiota, conferring health benefits to the host. In the present review, we have summarized the beneficial activities of various mushrooms on gut microbiota via the inhibition of exogenous pathogens and, thus, improving the host health.

    2. Paper regarding the use of Seaweeds as prebiotics:
    Prebiotics from Marine Macroalgae [seaweeds] for Human and Animal Health Applications
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920542/

    Abstract
    The marine environment is an untapped source of bioactive compounds. Specifically, marine macroalgae (seaweeds) are rich in polysaccharides that could potentially be exploited as prebiotic functional ingredients for both human and animal health applications. Prebiotics are non-digestible, selectively fermented compounds that stimulate the growth and/or activity of beneficial gut microbiota which, in turn, confer health benefits on the host. This review will introduce the concept and potential applications of prebiotics, followed by an outline of the chemistry of seaweed polysaccharides. Their potential for use as prebiotics for both humans and animals will be highlighted by reviewing data from both in vitro and in vivo studies conducted to date.

    3. Paper regarding the use of Humic Acids as prebiotics:
    Impact of humic acids on the colonic microbiome in healthy volunteers
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920542/

    Abstract
    AIM: To test the effects of humic acids on innate microbial communities of the colon.
    METHODS: We followed the effects of oral supplementation with humic acids (Activomin®) on concentrations and composition of colonic microbiome in 14 healthy volunteers for 45 d. 3 × 800 mg Activomin® were taken orally for 10 d followed by 3 × 400 mg for 35 d. Colonic microbiota were investigated using multicolor fluorescence in situ hybridization (FISH) of Carnoy fixated and paraffin embedded stool cylinders. Two stool samples were collected a week prior to therapy and one stool sample on days 10, 31 and 45. Forty-one FISH probes representing different bacterial groups were used.
    RESULTS: The sum concentration of colonic microbiota increased from 20% at day 10 to 30% by day 31 and remained stable until day 45 (32%) of humic acid supplementation (P < 0.001). The increase in the concentrations in each person was due to growth of preexisting groups. The individual microbial profile of the patients remained unchanged. Similarly, the bacterial diversity remained stable. Concentrations of 24 of the 35 substantial groups increased from 20% to 96%. Two bacterial groups detected with Bac303 (Bacteroides) and Myc657 (mycolic acid-containing Actinomycetes) FISH probes decreased (P > 0.05). The others remained unaffected. Bacterial groups with initially marginal concentrations (< 0.1 × 109/mL) demonstrated no response to humic acids. The concentrations of pioneer groups of Bifidobacteriaceae, Enterobacteriaceae and Clostridium difficile increased but the observed differences were statistically not significant.
    CONCLUSION: Humic acids have a profound effect on healthy colonic microbiome and may be potentially interesting substances for the development of drugs that control the innate colonic microbiome.

2

THE NEED FOR IODINE SUPPLEMENTATION

Dr. Hank Liers PhD iodine supplementationFred Liers PhD iodine supplementationThe Orthomolecular Medicine News Service (OMNS) published on June 12 “The Need for Iodine Supplementation.” We believe strongly in the need for iodine supplementation, especially given the fact that more than 90% of the US population is iodine deficient. For this reason we make available both Nascent Iodine and Lugol’s Iodine Solution 2 to our customers.

We present the full OMNS article (below), as a source of valuable information to our resellers and Creating Health Naturally readers. The factors contributing to massive-scale iodine deficiency remain virtually unchanged over decades. This has led to a greater need for educating health professionals and individuals about the critical importance of iodine supplementation.

Another useful article discussing the benefits of iodine supplementation was published August 2 by Dr. Mark Sircus, OMD: “Iodine, Thyroid and Low Body Temperature.” ~

The Need for Iodine Supplementation

by Wojciech Rychlik, PhD

(OMNS, June 12, 2017) Feeling tired, having low energy or depression, gaining weight, memory problems, having dry skin, dry mouth, or immune system issues? There is good chance your body needs iodine supplementation. Why iodine? Because this essential to human health element has been singled out as dangerous, for several obscure reasons, and it has been gradually eliminated from our diet, and even worse, replaced by its antagonist, bromine. This trend has been termed, iodophobia (1). It is a cause of widely occurring hypothyroidism in many developed countries.

Iodine: How Much?

Iodine deficiency is associated with (2, 3, 4):

  • Fibrocystic breast disease leading to breast cancer and stomach cancer
  • Goiter (enlarged thyroid)
  • Mental issues from reduced alertness, lowered IQ, autism to cretinism, lack of iodine for the fetus leads to cretinism, and in milder cases to autism and ADHD
  • Slow metabolism, leading to tiredness, sluggishness, fatigue, apathy, depression, and insomnia
  • Inability to produce saliva, dry skin, and lack of sweating
  • Lack of optimal detoxification, especially of bromides, fluorides, and heavy metals
  • Sensitivity to temperature changes, and cold hands and feet
  • Muscle pain, fibrosis, and fibromyalgia
  • Erectile dysfunction, infertility and miscarriages, and low sex drive
  • Overweight
  • High blood pressure, and increased incidence of heart attacks and strokes

The Food and Agriculture Organization (FAO) of the United Nations has published probable safe upper limits for dietary intake of iodine (5). They range from 150 micrograms (mcg) per kilogram (kg) per day in newborn infants to 30mcg/kg/day in adults. That is 2 milligrams (2,000 micrograms) daily for a 146-pound adult. The safe upper limit is higher during pregnancy and lactation (40 mcg/kg/day).

Treatments for Hypothyroidism

The simplest method to deal with an underactive thyroid is proper supplementation with iodine, called orthoiodosupplementation. If the thyroid is damaged, then supplementation with thyroid hormones, thyroxine (T4) and triiodothyronine (T3, the main biologically active hormone) may be necessary. Supplementation (6). with these hormones should be done under close supervision of a medical professional. However, supplementation with inorganic iodine is generally much safer, as the body “knows” how much T4 and T3 need to make. There are also drugs that change physiology of iodine metabolism, but this subject is beyond the scope of this article. Pharmaceutical companies pressure doctors to avoid inexpensive orthoiodosupplementation, so you won’t likely get a prescription for inexpensive Lugol’s solution from a mainstream practitioner.

One caveat to supplementation with iodine is the autoimmune illness called Hashimoto’s disease, or chronic lymphocytic thyroiditis, which is one of the potential causes of hypothyroidism. Unfortunately, when hypothyroidism is diagnosed, the possibility that Hashimoto’s disease underlies this condition has not always been properly tested. Therefore, Hashimoto’s disease has often been misdiagnosed. Doctors usually treat this condition with hormone replacement therapy, and some believe that excessive iodine intake may trigger it in susceptible people (7). Always ask your doctor if iodine supplements are right for you.

History of Iodine Usage and “Iodophobia”

This subject has been covered in detail by Dr. Guy E. Abraham (8,9,10). The iodine element was discovered in 1811 by B. Courtois. In 1850–1853 A. Chatin noted that goiter and cretinism are rare in geological zones rich in iodine and frequent where iodine is in short supply, and that goiter can be prevented by iodine supplementation. In 1895 E. Baumann proposed that iodine is the active element in the thyroid gland.

By the time Bauman identified large concentrations of iodine in the thyroid gland in 1895, pharmaceutical and apothecary preparations containing iodine, excluding thyroid extracts, were widely used as a panacea.

To quote Kelley: (11) “The variety of diseases for which iodine was prescribed in the early years is astonishing – paralysis, chorea, scrofula, lacrimal fistula, deafness, distortions of the spine, hip-joint disease, syphilis, acute inflammation, gout, gangrene, dropsy, carbuncles, whitlow, chilblains, burns, scalds, lupus, croup, catarrh, asthma, ulcers, and bronchitis – to mention only a few. Indeed, tincture of iodine, iodoform, or one of the iodides, was applied to almost every case that resisted the ordinary routine of practice; and between 1820 and 1840 there appeared a remarkable series of essays and monographs testifying to the extraordinary benefits to be achieved by this new and potent remedy.”

Unfortunately, these monographs have virtually disappeared from US medical libraries. In the mid-1800s, iodine treatments of some diseases called for ingestion of gram (1,000 mg) amounts per day. However, most treatments were from 5 to 50 mg daily. The recommended daily amount of iodine by Dr. G. E. Abraham is 0.1-0.3 ml Lugol containing 12.5-37.5 mg elemental iodine. This is the amount of iodine needed for whole body sufficiency, based on a recently reported iodine/iodide-loading test (12). Thyroid gland sufficiency for iodide is achieved with a lower dose.

Lugol's iodine supplementation

The first iodophobic authority emerged in early 1900s. Prof. T. Kochler reported that he suffered from overactive thyroid following ingestion of iodide (just a single individual case, not a statistical research study!) Despite this, the number of applications grew. In an International Index published in 1956, and devoted exclusively to iodine pharmaceuticals, no less than 1,700 approved iodine-containing products were listed. In 1948 Wolff and Chaikoff published that a serum inorganic iodide level at a concentration of 1 µM blocks (one micromolar) the synthesis of thyroid hormones, resulting in hypothyroidism and goiter in rats. But this conclusion was erroneous as they even did not measure thyroid hormones in the rats studied, and of course, hypothyroidism and goiter were not observed in those rats. Many organic forms of iodinated drugs were quite poisonous. Unfortunately, medical establishment did not make a distinction between organic and inorganic forms of iodine, and iodophobia became more popular.

Decades ago, iodine was added to bread so that one slice contained 150 mcg of iodine (the current recommended daily allowance). In the 1980s, bromine replaced iodine in bread. Since bromide is an antagonist to iodine (it is goitrogenic), it worsened iodine deficiency in the US. Moreover, a big push to remove salt from our diet (the only grocery item still supplemented with iodine) exacerbated the problem. The only developed nation that resisted iodophobia is Japan, statistically the healthiest and longest living nation on the planet. Their average daily consumption of iodine is around 5 mg, with various reports ranging from 1 mg to 18 mg. In a study of reported daily iodine intake versus total number of clinical symptoms, an intake of approximately 1 mg per day correlated with the lowest number of reported symptoms, that is, the highest level of health (13). Recent popularization of bromides in our food supplies likely increased this amount.

According to Dr. Abraham, (14) “proper amounts of iodine in the food supply should be considered one of a nation’s greatest assets. Removing iodine from the food supply is a major mistake. Supplying a daily intake of iodine sufficient for the whole body (100-400 times the RDA) gives protection against goitrogens and radioactive iodine/iodide fallout; improves immune functions, resulting in an adequate defense system against infection; decreases singlet oxygen formation which is the major cause of oxidative damage to DNA and macromolecules, resulting in an anticarcinogenic effect in every organ; results in a detoxifying effect by increasing urinary excretion of the toxic metals lead, mercury, cadmium, and aluminum, as well as the goitrogens fluoride and bromide; normalizes hormone receptor functions resulting in improved response to thyroid hormones both endogenous and exogenous; and results in better control of blood sugar in diabetic patients; stabilizes cardiac rhythm, obviating the need for the toxic sustained release form of iodine, amiodarone; and normalizes blood pressure without medication in hypertensive patients. Iodine deficiency is the major cause of cognitive impairment, worldwide.”

The Iodine-Cancer Connection

The body requires iodine to metabolize both omega-3 and omega-6 fatty acids. A substance called delta-iodolactone, a derivative of arachidonic acid, which is produced in the thyroid gland and breast tissue, prostate, colon, and the nervous system, is a regulator of a process called cellular apoptosis (“cell death”). Ascorbic acid is required to stimulate intracellular hydrogen peroxide synthesis that, in turn, provides the energy to make iodine free radicals necessary for this reaction. When the level of delta-iodolactone is high enough, the process of apoptosis can then kill cancer cells. (15)

Unfortunately, the recommended daily allowance (RDA) for iodine — about 150 mcg per day — will not allow delta-iodolactone to be efficiently formed in the thyroid gland. The thyroid requires higher iodine concentrations to efficiently produce it. Researchers have found that 100 times the RDA amount of iodine is optimal to produce delta-iodolactone. That equates to taking about 15 mg of iodine per day (15,16). These findings are important because they imply that there are some biochemical reactions that require much larger amounts of iodine than the current RDA. The mechanism by which delta-iodolactone induces cell death may be an important pathway for curing some types of cancer.

Forms of Iodine

Inorganic iodine exists in 6 oxidative states, from -1 to +7. The most reduced form (with most electrons) is iodide (I); an example is potassium iodide. The diatomic form of elemental iodine I2, has no electrical charge. Monoatomic iodine also has no electrical charge, but is unstable and highly reactive (free radical, labeled as an I with a dot, I* ). It can be produced by exposing I2 to ultraviolet light. Electric and magnetic fields won’t do it, as is sometimes incorrectly suggested. More oxidized forms of iodine are: hypoiodite (I+1), iodite (I+3), iodate (I+5), and periodate (I+7). The body’s metabolism may convert (reduce) these forms to biochemically available iodide, but at the cost of depleting its antioxidants. All forms of positively charged iodine are relatively poisonous, with established lethal doses (LD50) in the range of 35 to 2100 mg/kg. Elemental iodine (I2) and iodides (I) are non-poisonous. However, a bad “antiseptic” non-culinary taste of iodine (I2) suggests to our senses that this is not so good choice for supplementation.Nascent iodine supplementation

Despite that adverse taste, almost all the research on iodine supplementation has been done using Lugol’s Solution (17). The original solution is called 5% Lugol’s Iodine, but in reality it consists of 12.5% iodide/iodine or (I/[I3]) ions. Two drops of Lugol’s Solution (0.1 ml) contain 12.5 mg iodine/iodide mix. Iodine tablets that are a solid form of Lugol’s solution, were created to mask the taste and make the doses more precise for dietary supplementation.

I should mention a few points about Edgar Cayce’s atomidine. This famous visionary wrote several articles about the best form of iodine supplement (18). Some claim that this was iodine trichloride, but that cannot be true as this compound is toxic by ingestion and damaging to mucous membranes. It decomposes to ICl and poisonous gas Cl2 at 77 degrees C and also in water at room temperature (19). Most likely Cayce’s atomidine was simply a 1% iodine solution (I2) in 95% ethanol. I am surprised that there are educated people, even medical doctors who claim that “elemental monoatomic iodine” preparations (Atomidine, Nascent Iodine etc.) are the best forms of iodine supplements. May be it has something to do with efficient marketing? Elemental Iodine (I2) is soluble in glycerin. Replacement of ethanol with glycerol indeed makes these supplements more consumption-friendly, so they are sold by some vendors as superior products to Cayce’s ethanol-formulated one. Personally, I think glycerol-based I2 supplements are inferior to iodides; however, they are excellent antiseptics.

To defend the validity of Cayce’s vision, in thyroid, I ion and amino acid tyrosine react through a short intermediate step by forming monoatomic I* free radical (selenium and hydrogen peroxide are involved) to make monoiodotyrosine. Diiodotyrosine is formed analogical way, and finally, two of these molecules combine to produce thyroxine. All those steps are carried by the enzyme thyroid peroxidase, which is normally attached to the protein thyroglobulin. So, yes, monoatomic iodine I* exists in human bodies, and it directly reacts with tyrosine, but no, it wouldn’t be healthy to consume iodine free radicals as their high reactivity would prevent safe transport throughout the body.

In the mid-1930s the thyroid hormone thyroxine became available on the market. This was a blessing for people who had damaged their thyroid. Unfortunately, doctors started to prescribe this hormone to just about anybody with hypothyroidism, thinking that they can control better thyroid hormone levels than our bodies can. And, the “iodine is iodine, no matter what form” mentality became a dangerous trend, because most medical professionals do not fully appreciate the difference between the raw nutrient (iodine) and its product (hormone).

The pharmaceutical industry came up with lots of organic forms of iodine (NB: organic, meaning that iodine is bound to a carbon-atom-containing molecule and NOT meaning it’s grown in a pesticide-free environment), all relatively toxic and certainly not to be used without strict medical supervision. Only inorganic forms of iodine, I and I2, are safe for supplementation (20,21). Further, high doses of these supplements should still be supervised by your doctor.

Iodine Uses

Iodine plays critical role in human metabolism. Many researchers believe the RDA value of 150 mcg for iodine is too low, especially when this element is commonly substituted with competing element bromine. Therefore, the main use of iodine in dietary supplementation is to enable optimal thyroid function. There are a number of medical conditions where iodine is either essential or helpful. For best results, iodine/iodide should be supplemented with selenium, magnesium, copper (there is usually enough of it in tap water as copper is widely used in plumbing), vitamin B2 (riboflavin) and B3 (niacin). Ask your doctor before taking any iodine supplements, especially if you are on medications.

Elemental iodine (I2) is antibacterial and antifungal, so iodine or iodine/iodide solutions are commonly used topically to sterilize wounds, or internally to fight infections, such as vaginitis and sore throat, and also to sanitize drinking water. Because iodine is antibacterial, drinking it may cause friendly bacterial flora to suffer and result in diarrhea and stomach cramps (the same applies to Lugol’s solution, but to a lesser extent as it contains iodides as well).

Ingestion of iodides prevents the incorporation of destructive radioactive iodine into the body (mainly by the thyroid) in case of nuclear accidents. It also may help flushing already incorporated radioactive iodine from the thyroid, although too much iodine inhibits secretion of T4/T3 from the gland.

Common-Sense Cautions

Overdosing any of the iodine supplements can lead to swollen salivary glands, metallic aftertaste and skin rash and itching (that are usually due to rapid process of detoxification from heavy metals fluorides and bromides), faster heartbeat or palpitations and diarrhea. When supplementation is stopped, these symptoms will usually disappear quickly, often within one day. Iodine stabilizes thyroid hormone production, so it is an adaptogen, but in rare cases, such as acquired allergy to iodine (Hashimoto’s disease), it may actually misbalance it. In some cases, iodine supplementation can cause hypothyroidism, so it’s important to get checked by your doctor to make sure that your thyroid function is not worsened by supplementation. Some authors advising caution are Alan Christianson (22), Jeffrey Dach, (23) and Alan Gaby (24). Testing of levels of thyroid hormones along with testing and supplementation of mineral nutrients such as selenium, zinc, copper, magnesium calcium, and other trace minerals may prevent problems in cases where high doses of iodine/iodide might tend to cause Hashimoto’s disease. (23)

Inorganic Iodine Availability

The most common form of iodine supplement is Lugol’s solution (17). The original solution contains 5% of iodine and 10% iodide. Solid pill forms of Lugol’s solution are sold under several brand names. Potassium iodide (KI), my favorite iodine supplement, is available as tablets as well. Various products with kelp or other seaweed extracts contain iodides as well. Check the label when you buy as some of them are very diluted.

It is difficult to find inexpensive elemental iodine (I2) solution in alcohol. You can buy iodine crystals online and make the proper solution by yourself very easily (using either alcohol or glycerol). The monoatomic iodine concept is simply a marketing gimmick that has been created to inflate the price several fold. Note that if the monoatomic claims were really true, few would really want to drink free radicals, the only monoatomic form that exists. Iodine free radicals are not transported freely in our bodies because they are too reactive. Elemental iodine preparations, including iodine dissolved in glycerol, may be helpful products for external antiseptic use rather than a supplement.

Another form of iodine supplement includes a mixture of algae and thyroid extract in glycerin, water and ethanol. This is likely not harmful because it contains T3 and T4 only in very small amounts, and the recommended serving size is also small. Other complex formulae that contain elemental iodine are a useful antiseptic, but not a good supplement. Iodine trichloride should be avoided as a supplement because it is too toxic.(19)

Summary

The established RDA allowance for iodine (150 mcg/day) is inadequate for many individuals. In order to maintain optimum health, adults need 2-5 mg of iodide daily. Actually, this is in line with the upper safe limit of dietary intake of iodine established by FAO (30 mcg/kg/day). In case of a dysfunctional thyroid or other illnesses, such as fibrocystic breast disease or cancer, 15-50 mg daily may be needed. Ask your doctor about the alternatives to hormone therapy or taking iodine-containing organic drugs, because inexpensive orthoiodosupplementation would usually not be his/her first choice.

The best and safest form of iodine supplementation for a healthy adult is iodide. Iodides are naturally produced in larger quantities by various seaweeds.

Please consult your doctor about iodine supplementation, as in your particular case it may be contraindicated.

References:

1. Abraham GE. The History of Iodine in Medicine Part III: Thyroid Fixation and Medical Iodophobia. http://optimox.com/pics/Iodine/IOD-16/PUB_16.htm

2. Dommisse J. MD Best Kept Secret (2009) http://www.westonaprice.org/modern-diseases/best-kept-secret/#sthash.vdrKPaJw.dpuf

3. http://theiodineproject.webs.com/addadhdautism.htm

4. Hamza RT1, Hewedi DH, Sallam MT. (2013) Iodine deficiency in Egyptian autistic children and their mothers: relation to disease severity. Arch Med Res. 44(7):555-61. http://www.ncbi.nlm.nih.gov/pubmed/24120386

5. http://www.fao.org/docrep/004/y2809e/y2809e0i.htm

6. Abraham GE. The Concept of Orthoiodosupplementation and Its Clinical Implications. https://www.optimox.com/pics/Iodine/IOD-06/IOD_06.htm

7. http://www.webmd.com/women/hashimotos-thyroiditis-symptoms-causes-treatments#1

8. Abraham GE. The History of Iodine in Medicine Part I: From Discovery to Essentiality. http://optimox.com/pics/Iodine/IOD-14/PUB_14.htm

9. Abraham GE. The historical background of the Iodine Project. http://www.optimox.com/pics/Iodine/IOD-08/IOD_08.htm

10. Abraham GE. The History of Iodine in Medicine Part II: The Search for and the Discovery of Thyroid Hormones. http://optimox.com/pics/Iodine/IOD-15/PUB_15.htm

11. Kelly FC. “Iodine in medicine and pharmacy since its discovery , 1811-1961.” Proc R Soc Med, 1961; 54:831-836. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1869599/

12. Abraham GE. “The safe and effective implementation of orthoiodosupplementation in medical practice.” The Original Internist, 2004; 11(1):17-36. http://www.hakalalabs.com/Research/Abraham_OI_Mar04.pdf

13. Fallon Morell S. The Great Iodine Debate (2009) The WestonA. Price Foundation, http://www.westonaprice.org/modern-diseases/the-great-iodine-debate/

14. Abraham GE. The Wolff-Chaikoff Effect: Crying Wolf? https://www.optimox.com/pics/Iodine/IOD-04/IOD_04.html

15. Brownstein D. The Cancer-Iodine Connection, (2015) http://www.newsmax.com/Health/Dr-Brownstein/iodine-cancer-cell-death-fish-oil/2015/06/10/id/649877/

16. 6-Iodolactone, key mediator of antitumoral properties of iodine, M. Nava-Villalba, C. Aceves, (2014) Prostaglandins & Other Lipid Mediators 112, 27-33. https://www.researchgate.net/publication/263856609_6-Iodolactone_key_mediator_of_antitumoral_properties_of_iodine

17. Bacteriological Analytical Manual, R40 Lugol’s Iodine Solution (2001), http://www.fda.gov/Food/FoodScienceResearch/LaboratoryMethods/ucm062245.htm

18. Review of Atomidine, International Wellness Directory, http://www.mnwelldir.org/docs/reviews/atomidine.htm

19. Material safety data sheet, http://www.mnwelldir.org/docs/history/Iodine_Trichloride.pdf

20. Abraham GE. The historical background of the Iodine Project http://www.optimox.com/pics/Iodine/IOD-08/IOD_08.htm

21. Abraham GE and Brownstein D. A Rebuttal of Dr. Gaby’s Editorial on Iodine. (2005) Townsend Letter, The Examiner of Alternative Medicine, http://www.townsendletter.com/Oct2005/gabyrebuttal1005.htm

22. Christianson A. http://www.integrativehealthcare.com/why-i-discourage-high-dose-iodine/

23. Dach J. http://jeffreydachmd.com/iodine_is_safe

24. Gaby A. http://www.townsendletter.com/AugSept2005/gabyiodine0805.htm

Nutritional Medicine is Orthomolecular Medicine

Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

Access the original OMNS article, “The Need for Iodine Supplementation”: http://www.orthomolecular.org/resources/omns/v13n14.shtml

OMNS free subscription: http://orthomolecular.org/subscribe.html

OMNS article archive: http://orthomolecular.org/resources/omns/index.shtml

0

RELIEF Rx™ REMEDY FOR MUSCLES, SKIN, AND JOINTS

Dr. Hank Liers, PhD Relief Rx™ pain sore musclesOne of our suppliers recently sent me a new product sample called Relief Rx™ to evaluate. The product is a topically-applied fast-acting “Aloe vera relief gel” for sore muscles, back, joints, and skin.

ReliefRx

After I applied the gel to painful or sore spots on my body, my pain and soreness was relieved in a short time — 15 minutes or less! I was quite impressed, needless to say. The gel has no odor and after it dries, it leaves no messy oils etc. on your skin—unlike many other topical skin formulas.

Because Relief Rx™ is a new product there are no prior sales data. However, our supplier also sent product samples to many other people who agreed to try it. The results experienced by the testers were nothing short of amazing — see some of their testimonials below.

 

 

RELIEF Rx™ INGREDIENTS

Aloe vera, a primary ingredient in Relief Rx™

Aloe vera is a primary ingredient in Relief Rx™

Aloe vera (organic)

The Egyptians called Aloe vera the “plant of immortality.” Aloe has been cultivated for centuries by indigenous people from Africa to Asia, and it is revered around the world by herbalists. As such, it may be the ultimate resource nature has provided for natural health.

The aloe extract in Relief Rx™ is carefully prepared with 100% organically grown plants, then compounded with a proprietary process to provide highly bioavailable constituents, such as acemannan and a full-spectrum of natural polysaccharides. Some of the known helpful effects of acemannan include:

  1. Helps cells to be more resistant to viruses and pathogenic bacteria.
  2. Improves overall cellular metabolism and functioning.
  3. Promotes healthy inflammation response.
  4. Provides critical lubrication of joints.
  5. Reduces pain.
  6. Improves vascular flow.
  7. Reduces scarring.
  8. Improves healthy macrophage activity.
  9. Increases the body’s own production of interferon, interleukins.
  10. Increases the number and activity of killer T-cell and increase monocyte activity.
  11. Fights fungal infections, such as: Athlete’s foot, Ringworm, Pruritus anivalvae, Balnea, Essential Pruritus, and Vaginal yeast infections/
  12. Helps athletic injuries such as: Muscle cramps, Sprains, Strains, Bruises, Swelling, Soreness, Tendonitis, and Bursitis.
  13. Helps with harmful organisms.
  14. Speeds wound healing..
  15. Anti-aging properties. Stimulate fibroblasts to release collagen and elastin to make new tissue.

You will feel the quality of the Aloe vera at work with every application.

Hemp

Hemp

Hemp Oil:
The hemp oil in Relief Rx™ is extracted from the flowers and leaves of the revered hemp plant. It is especially rich in bioactive molecules (without any psychotropic effects or side effects) and has gained worldwide recognition as a natural and potent therapeutic nutrient.

Select hemp oil molecules interact with our inherent endogenous cannabinoid (endocannabinoid) system to carry out beneficial and protective physiological reactions. First discovered in the late 1980s, the endocannabinoid system supports the body’s complex regulatory mechanisms including mood, sleep, appetite, hormones, pain, and immune response.

Relief Rx™ utilizes an advanced proprietary science that greatly enhances the efficacy of hemp oil to achieve results that are unequaled by conventional products.

White Willow Bark Extract (Salix alba)

White Willow Bark Extract (Salix alba)

White Willow Bark Extract (Salix alba):
A native of Europe and Asia, the name of this deciduous tree comes from the lightly colored undersides of its slender leaves. Willow may in fact be one of the oldest remedies, used in ancient Egypt and China as early as 500 BCE.

Healers applying skin and beauty treatments understood that willow bark was an important ingredient in the support of natural health. Careful processing ensures that the willow extract in Relief Rx™ contains the highest purity of ingredients. Benefits of using white willow bark extract include:

  • Anti-aging: A 2010 study reported that salicin can help reduce the appearance of skin aging. Researchers applied a serum product containing 0.5 percent salicin on the faces of women aged 35 to 70, every day for 12 weeks. Results showed improvements in the appearance of wrinkles, pore size, radiance, and overall appearance after only one week.

  • Helps cleanse oily skin: Willow bark extract naturally exfoliates skin and clears pores to give skin a clearer, healthier appearance.
  • Smooths the appearance of fine lines and wrinkles: The same exfoliating action that reduces clogged pores also helps smooth the look of fine line and wrinkles. Willow bark is a source of natural hydroxy acids that gently exfoliate. The result is smoother, softer skin.
  • Antioxidants: Like most plant extracts, willow bark contains flavonoids and tannins—powerful antioxidants that help protect skin from environmental stressors.
Relief Rx™ contains important trace minerals

Relief Rx™ contains important trace minerals

Ionic Trace Minerals Blend:
There is a great deal of evidence that the healthy function of the body is strongly influenced by electrical impulses. That is, our bodies use electrical impulse pathways, and electrolytes and ions are the conductors of these currents maintaining a smoothly running body. Ions provide the necessary charge of both positive and negative molecules that keep the electrical component of the human battery “charged” and working in top form.

The human skin is the largest organ of the body and is highly involved in the detoxification and maintenance processes of health. Skin not only excretes and eliminates toxins; it also has a tremendous capacity to absorb health supportive substances.

Clinical researchers have continued to document the clinical findings that have been observed for decades when it comes to the healing properties of topical minerals. Many of the studies on therapeutic baths have used minerals from the Dead Sea as well as the Great Salt Lake. Of particular interest are the powerful effects of these salts that exhibit favorable effects in inflammatory disease.

In one study, 103 arthritic patients received various bath treatments with ionic trace minerals. The study showed impressive results and those with the greatest physical limitation had the most pronounced improvement. A large percentage of the patients reported having less pain, improved mobility and were able to decrease analgesic use. In a different double-blind study, the use of warm mineral baths demonstrated a lasting effect for patients suffering from degenerative arthritis.

In a clinical trial conducted by a leading research university in Germany, patients with atopic (eczema) skin disorders immersed their arms in a mineral rich bath. The participants immersed one arm in tap water the other in the therapeutic mineral rich bath. The findings showed that skin hydration was improved and skin roughness and inflammation was reduced when immersed in the mineral rich water.

RELIEF Rx™ USAGE

Direction for use:
Apply a generous amount of gel to stressed muscles and joints as needed for soothing harmonious comfort, creating a moist surface. Allow the moisture to absorb naturally into the skin and air dry on its own. Keep tightly sealed and away from children. For external use only.

Ingredients:
Purified water, Glucomannan, Organic Aloe vera, Ionic Trace Elements Blend, Hemp Oil, White Willow Bark Extract, Citric Acid, Potassium Sorbate, Sodium Benzoate.

RELIEF Rx™ TESTIMONIALS

Relief Rx™ is a new product with no prior sales data. The product was sent out to a number of people who agreed to try it. The results obtained were amazing as shown in the testimonials given below. Personally, we can confirm that the product works extremely well for a variety of muscle and joint issues – usually providing sustained relief within a short time after applying the gel to the skin.

1. Ole G., Topanga, California: “I am an 88-year old retired mechanical engineer with multiple knee, hip and upper back chronic discomfort, that is UNTIL I FOUND Relief Rx. All of it was gone in a matter of minutes. I now use this gel only when I over exert myself during yard work and gardening. I love this product…!!”

2. Paul G.: “In all of my 35+ years in the fitness facility business I never saw a relief product that works as good as Relief Rx™. This stuff is on the verge of being miraculous……truly amazing”

3. Charlie L: “I had a slight tear in the meniscus of my left knee that bothered me if I stood or sat for long. I applied Relief Rx™, and was amazed. In less than 20 seconds – literally, my knee was back to normal. I wasn’t expecting it to work that well or that quickly.”

4. Katie L (49): “I have used the Relief Rx™ many times when my muscles have been sore or my joints achy and each time, within minutes, the pain has diminished if not gone away completely. I don’t really understand why this happens, I just know it does. I appreciate the simplicity of the liquid – it is not thick, or smelly or difficult to use. And it seems to absorb quickly. It does not leave behind residue, any fragrance or greasy feeling. So I’m not so sure what is in it. I just know that it works wonders. Thank you for bringing this product to market. I’ve thrown out all of my other products and just use this.”

5. J.G.: “I have had severe pain in my right hand for over two years from using the mouse, pain in my arm, and recently I had surgery and developed a very uncomfortable pain on my right side from lying in bed. Every time I use Relief Rx™ I am amazed at how quickly the pain subsides and disappears. Thank you for this wonderful product!”

6. Dr. Chuck A.: “I applied Relief Rx™ on a patient that had nagging back issues. She told me she had “immediate and significant relief”. When can I get more?”

7. Mike G.: “I have played handball for 50 years. Over that time I have suffered right shoulder problem from injury, strain from over use, and tension from rotator cuff surgery. Over the past 15 years I have had to change shots due to shoulder problems and limitations. I applied Relief Rx™ and within 30 minutes I was 100%! I can hit all of the shots on the handball court like I could 15 years ago.”

8. U.: “This is the most amazing relief product I have ever experienced. I have disturbing problem in my back and it prevents me from getting a full nights sleep. Last night is the first night of continuous sleep I’ve had in more than a year.”

0

Microbiome, Diet, and Prescript-Assist Probiotic & Prebiotic

Fred Liers PhD microbiome health probiotics prebioticsGut health is paramount to overall health. This was known in ancient times. According to the 4th-century (BCE) Greek physician Hippocrates, “All disease begins in the gut.” And since our founding in 1988, we at Health Products Distributors, Inc. (HPDI) have recognized the importance of supporting a healthy microbiome through diet, lifestyle, and the use of probiotic supplements.

We have written blog articles on developments regarding the microbiome, including “The Advantages of Soil Based Organisms for Health” (2014) and Dr. Hank’s short piece “A New View of the Role of Bacteria for Health” (2012).

However, the scientific understanding of the microbiome continues making quantum leaps. Every month it seems there is another groundbreaking study reported, or fresh information about the human microbiome highlighting specific aspects of its fundamental role in human health.

Gut health is paramount for good health.

Gut health is paramount for good health.

For example, studies showing the microbiome’s significance for brain function, digestive tract health, leaky gut, immune system function, and lifelong health. And even more, studies revealing potential connections between microbiome status and conditions involving the gut-brain axis, such as gluten sensitivity, celiac disease, ADHD, autism, depression, Parkinson’s disease, and Alzheimer’s disease.

As exciting as the studies are on a theoretical level, one of the main benefits is that many of them point to practical applications and suggestions that can be implemented on a daily basis by individuals wishing to improve microbiome health and vitality.

Information about means you can take to improve microbiome health is increasingly available not only in the scientific literature (which can be searched for in places like PubMed), but also in the popular media. For example, books like Dr. David Perlmutter’s Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life (2015) include dietary recommendations and recipes. In addition, there are numerous books and online resources for making your own cultured foods (everything from kombucha tea to fermented condiments), as I will talk about more below.

sauerkraut kimchi yogurt probiotic fermented food microbiome

Fermented foods like sauerkraut, kimchi and yogurt provide beneficial bacteria.

Increasingly, individuals are speaking with their nutritionist or doctor on this topic, as knowledge of the important role of foods and nutrition in supporting a healthy microbiome.

While at the ACAM (American College for Advancement in Medicine) annual meeting in Las Vegas in November, I attended a presentation by Raphael Kellman, MD. He discussed the importance of the microbiome for supporting health, and the positive effects related to maintaining populations of beneficial flora, including the fact that probiotics can support positive emotions.

I present a few recommendations for supporting and improving microbiome health through lifestyle, dietary choices, and the use of probiotic supplements.

DIETARY RECOMMENDATIONS FOR MICROBIOME HEALTH

Dietary choices are among the simplest, yet most effective means for effecting improvement  in the human microbiome. Here are some dietary recommendations that are known to work.

Consume Foods High in Probiotics, including Fermented Foods. Foods high in probiotics include yogurt, kefir, sauerkraut, kim chee, tempeh, pickles and other pickled vegetables, and kombucha tea.

Probiotic foods provide you directly with good-for-you bacteria that help keep your microbiome diverse and well balanced.

Historically, many of the most important bacteria for gut health are lactobacteria and bifidobacteria. Some of the most well-recognized strains of these types include L. acidophilus, B. longum, B. bifidum, L. fermentum, and L. rhamnosus.

Notably, studies indicate reduced levels of lactobacteria and bifidobacteria in depressed individuals. While these two types of bacteria are perhaps the most studied and well-known, there are hundreds or thousands of different types of beneficial bacteria in the human microbiome. I will talk more about some of them when I discuss soil-based organisms.

Source probiotic foods that are organic, biodynamic, garden grown, and free-range / pasture-raised (e.g., dairy products). For pickles and relishes should preferably be unpasteurized and fermented in brine.

Consume Prebiotic Foods. It is important to consume foods that provide non-digestible short-chain fatty acids (SCFA) that support a flourishing good-for-you microbial community. Prebiotic foods include onions, garlic, asparagus, radishes, beans, oats.

Many prebiotic foods contain relatively high amounts of inulin, which is a soluble dietary fiber and a naturally occurring oligosaccharide. Inulin belongs to a class of carbohydrates called fructans.

Inulin selectively feeds beneficial bacteria. Major inulin-containing foods include Jersusalem artichoke (sunchokes), bananas, leeks, beets, and certain herbs. Chicory root, elecampane root, and dandelion root are especially high in inulin.

The fermentation of indigestible complex carbohydrates like inulin (and other natural dietary fibers) in the digestive tract results in the production of short-chain fatty acids that feed beneficial microbiota.

asparagus prebiotic microbiome beneficial bacteria

Asparagus contains the prebiotic inulin.

The three primary short chain fatty acids created by gut bacteria are acetic, butryic, and propionic acids. These fatty acids are excreted or absorbed by the colon and used for energy by cells. For example, butyric acid provides fuel for cells lining the colon and is associated with positive benefits.

Because different bacterial species produce different fatty acids, the ratio of the different species is important for health. In particular, butyric acid is associated with positive health benefits.

In contrast, clostridial species produce proprionic acid (PPA), which is too high quantities is known to exert adverse effects in the body, including the brain. Interestingly, studies show that autistic individuals harbor more clostridial species some of which are remarkably absent in normal populations.

At least one comparative study showed the the microbiomes of urban, Western populations (consuming more refined foods) produce relatively high levels of proprionic acid whereas the microbiomes found in rural, non-western populations (consuming more dietary fiber) produce more butyric acid.

Other studies indicate that the microbiome of rural populations predominantly contains bacteroides type flora (associated with lean body mass) and urban populations contain primarily firmicutes (associated with obesity when predominant).

Consume vegetables, including leafy green vegetables: Diets that include relatively high amounts of greens are beneficial for feeding a diverse and healthy microbial community. This is not only because of high-nutrient density and dietary fiber, but also due to the beneficial bacteria naturally present in these foods.

Reduce intake of sugars, especially refined sugars and high-fructose corn syrup. Natural sugars in fruits and vegetables are generally better to consume because they are ingested along with dietary fiber as part of the whole food. Refined sugars and especially high-fructose corn syrup (HFCS) test the body’s capacity for dealing with sugar, stress the body, prematurely age cells (via glycation processes), and promote adverse changes that can ultimately lead to diabetes.

Avoid foods containing antibiotics. Antibiotics in foods damage the microbiome by killing bacteria (including beneficial bacteria), reducing microbial diversity, and leaving the microbiome vulnerable to hostile takeover. Thus, consume only free-range, antiobiotic-free meats, eggs, and poultry. Avoid factory farmed meats and farmed fish.

Avoid simple carbohydrates. Like refined sugars, refined carbohydrates and grain products are notorious culprits for producing an imbalanced microbiome. So, avoid overconsuming processed grains, especially those containing wheat.

Avoid gluten. Wheat and the gluten it contains has been implicated in adverse conditions for the microbiome. Yet, wheat isn’t the only food containing gluten. While this may sound like advice given only for celiacs or IBS patients, the picture emerging regarding gluten is that it is associated with adverse changes in the microbiome. Similarly, adverse changes in the microbiome are associated with the development of gluten sensitivity and celiac disease.

one hundred percent organic

Organic and biodynamic foods support a healthy microbiome.

Avoid genetically modified foods (GMOs). The consensus is emerging that genetically modified (or genetically engineered) foods contribute to problems in the microbiome. Herbicides used on GMO crops, such as glyphosate, harm the microbiome and contribute to states of depleted nutrition.

Avoid artificial sweeteners. As bad as refined sugars are for the microbiome, artificial sweeteners can be just as bad or worse. Beyond the fact that artificial sweeteners tend to be toxic, they are known to produce adverse changes in the microbiome.

Choose organic, biodynamic, pesticide-free, and garden-raised. Regarding food choices, do your best to obtain naturally grown foods and to avoid agricultural chemicals.

LIFESTYLE CHOICES SUPPORTING THE MICROBIOME

Avoid Antibiotics. Whenever possible, avoid taking antibiotics. These can destroy the balance in your microbiome.

Avoid antimicrobial products. These include soaps (containing triclosan and other chemicals), antimicrobial coatings (like Microban), and antibacterial substances.

Avoid chemicals that affect your microbiome. For example, avoid products and foods with synthetic, toxic preservatives. Drink filtered water (i.e., non-chlorinated water).

Get Dirty. Try gardening, spend time outdoors, or just be in nature more often. Unpolluted soils are an excellent source of natural microbes needed to keep you microbiome in balance.

PROBIOTIC & PREBIOTIC SUPPLEMENTATION

In addition to consuming probiotic and prebiotic foods, it can be helpful to take a probiotic supplement. Many of the probiotic supplements on the market provide a full complement of lactobacteria and/or bifidobacteria (often in the same formula).

It is especially useful to take probiotic supplements after exposure to antibiotics. However, probiotic supplements can offer be an effective adjunct to a probiotic (and prebiotic) friendly diet.

More recently, soil based organisms have garnered attention as important constituents of a healthy microbiome. These differ from lactobacteria, and in many ways are hardier and easier to get into the gut where they can thrive. It is also known that fulvic and humic acids act as prebiotics feeding microbes found in soils (soil based organisms) that support human health.

WHAT ARE SOIL BASED ORGANISMS (SBO)?

There are thousands of different types of bacteria found naturally in soils. These bacteria in soil and dirt historically performed many beneficial functions for us. It appears they help our bodies regulate immunity, and protect us from bacterial and fungal overgrowths in our intestinal tracts.

Up until 100 years ago (or less for some people), soil based organisms were an everyday part of the diet. Not that long ago, our country was comprised mostly of farmers. Agriculture was more about getting dirty than about efficient machinery and chemicals inputs (i.e., industrial agriculture). At that time, almost everyone would have consumed soil based organisms on vegetables and other foods from the fields, gardens, and orchards.

Today due to lack of exposure to soil based organisms resulting from modern food processing systems and the extensive use of pesticides that destroy the organisms, the average person has a very different composition of intestinal flora from their ancestors. There are far fewer soil based organisms, and more lactic acid bacteria. In addition, the use of antibiotics for young children has further swayed the balance away from these beneficial bacteria.

soil based organisms carrots

Healthy soils host soil based organisms. Foods grown traditionally without the use of synthetic herbicides and fertilizer provide high levels of SBOs naturally.

With a dramatic rise in research into the benefits of soil based organisms, new products have been developed that help us reintroduce them into our intestinal tracts. There they offer many benefits, including improving digestion, boosting immunity, and supporting overall good health in the intestines (with such benefits as reduced bloating, flatulence, and constipation).

And for example, certain soil based organisms are known to secrete proteins activating the immune system, as well as stimulating the production of white blood cells and antibodies.

BENEFITS OF SOIL BASED ORGANISMS

Increasing evidence supports the idea that soil based organisms are essential for human health. Here are a few of the reported benefits:

  • Improved Gastrointestinal Health
  • Prevention of Gut Colonization by Harmful Bacteria and Fungi
  • Support for Intestinal Regeneration
  • Support for Balancing Gut Microbiota
  • Help Balance Colon pH
  • Increase Resistance to Harmful Bacteria and Fungi
  • Increase Absorption of Nutrients in the Intestines
  • Help Replenish Friendly Microflora in the Colon
  • Support Overall Health and Well Being
  • Enhance Metabolism in the Gut
  • Promote and Normalize Bowel Function
  • Help Reduce Gas and Bloating
  • Improve Immune System Function
  • Improve GI Tract Barrier Function
  • Many Other Benefits

SOIL BASED ORGANISMS ARE DIFFERENT THAN LACTOBACTERIA

Most people today either take or are aware of the benefits of probiotics containing lactic acid-based bacteria. These include commonly known strains of lactobacilli and bifidobacteria. Lactic-acid bacteria certainly are beneficial. There is a large body of research showing their high value for supporting digestion, immunity, and many other benefits. But they do have certain limitations.

Many of the lactic acid bacteria in probiotic formulas have difficulty making it through the stomach’s acidic environment. Thus, the bacteria arrive in the small intestine in vastly reduced numbers compared to the amount that must be consumed. Nutritionists therefore usually recommend taking probiotics with a large number of “colony forming units” (CFU) in order to ensure viability of the bacteria.

In addition, the benefits conferred by taking lactic acid bacteria may depend upon continuing usage. That is, certain studies indicate the benefits of these bacteria are greatly reduced after usage ends.

Soil based organisms offer several advantages compared to lactic-acid bacteria. First, they are extremely hardy and better able to withstand the acidic environment in the stomach. They are in fact, “endospore-forming” bacteria that surround themselves in a hard exterior that travels more effectively through the intestinal tract.

This means soil based organisms are far more likely to arrive intact in the small intestines (where they need to be) than lactobacteria. It also means that products containing soil-based organisms can provide fewer colony forming units and still be effective. That is, probiotic supplements with soil based organisms are more efficient at getting CFUs into the small intestines. It also eliminates or reduces the need for special coatings,  manufacturing processes, or “delivery systems” that must be created as a means to improve delivery rates of lactic acid bacteria.

Soil based organisms have also been shown to colonize the gut more effectively than lactic-acid bacteria. This may partially relate to the fact that they are hardier and make it to the small intestines in greater numbers. A major benefit is that this characteristic of SBOs may allow a reduction is dosage onto a “maintenance” level sooner without concerns that benefits of probiotic supplementation will disappear.

PRESCRIPT-ASSIST™ BROAD-SPECTRUM PROBIOTIC & PREBIOTIC

We at Health Products Distributors, Inc. researched various products containing soil based organisms. We choose to carry Prescript-Assist™, which is an effective and well-regarded broad spectrum probiotic and prebiotic formula.

Prescript-Assist™ provides 29 naturally resilient strains that support your body’s natural intestinal balance. Having so many strains means that this formula better reflects the great microbial diversity of the intestines versus typical probiotic products. In fact, more than 1,000 different species of microbes inhabit the human gut. Prescript-Assist™ includes Bacillus subtilis, which is a well-proven probiotic species found in traditional foods.

Below is a complete list of the strains of soil based organisms provided by Prescript-Assist. One 600 mg capsule of Prescript-Assist includes the following microorganisms (as well as the prebiotic Leonardite):

Arthrobacter agilis, Arthrobacter citreus, Arthrobacter globiformis, Arthrobacter luteus, Arthrobacter simplex, Acinetobacter calcoaceticus, Azotobacter chroococcum, Azotobacter paspali, Azospirillum brasiliense, Azospirillum lipoferum, Bacillus brevis, Bacillus marcerans, Bacillus pumilus, Bacillus polymyxa, Bacillus subtilis, Bacteroides lipolyticum, Bacteriodes succinogenes, Brevibacterium lipolyticum, Brevibacterium stationis, Kurthia zopfii, Myrothecium verrucaria, Pseudomonas calcis, Pseudomonas dentrificans, Pseudomonas fluorescens, Pseudomonas glathei, Phanerochaete chrysosporium, Streptomyces fradiae, Streptomyces cellulosae, Streptomyces griseoflavus.

The number and types of species found in the gastrointestinal (GI) tract can be a major difference between a well functioning digestive system and immune system, and those less than optimally functional. In scientific studies, individuals exhibiting higher levels of gastrointestinal distress and gut irregularities have been found to have a correspondingly lower variety of beneficial bacteria in the intestines.

Benefits of Probiotics soil based organisms

Benefits of probiotics, including SBO formulas like Prescript-Assist

INHERENT VIABILITY

Prescript-Assist™ is a clinically proven probiotic supplement designed to ensure maximum viability of the many organisms it provides. The formula offers inherent viability because the species it provides are naturally adapted for survival in the human gastrointestinal tract. That is, these 29 species are environmentally based (SBO) species drawn from the terrestrial microbiome where they have prospered and adapted for millenia to beneficially coexist with humans.

Unlike conventional Lactobacillus and Bifidobacterium probiotics, the strains in Prescript-Assist are a balanced formulation of a new generation of probiotics, capable of forming a protective shield until reaching the probiotic-friendly environment of the intestines. These organisms are resistant to acid, bile, and heat. In fact, routine testing of Prescript-Assist confirms it has a 95% viability two years after date of manufacture.

The inherent viability of the soil based organisms in Prescript-Assist means there are no requirements for nano-encapsulation or hard-shelled enteric-coated capsules, which both are essentially attempts to force viability of probiotic species rather than utilizing hardy strains naturally preadapted to our bodies.

Typical probiotic formulas therefore contain the relatively low-viability lactic acid bacteria that must be protected by technologies (e.g., microencapsulation) due to their inherent fragility. These fragile bacteria have a difficult time surviving because they are readily destroyed within the acidic environment of the stomach. Although patented enteric coatings can help survival rates, the provision of high-viabiltiy organisms that reach the intestines intact due to the inherent strength of their natural spore structure makes more sense as a means to protect against degradation in the stomach and intestinal tract.

Prescript-Assist™ provides bacteria that reach the intestines intact due to the fact that the spore structure protects against degradation or destruction by stomach acids.

probiotics-pros-cons soil based organisms

Benefits of soil based organisms in Prescript-Assist versus lactic acid bacteria formulas

29 SYMBIOTIC SPECIES FOUND IN ORGANIC, FERTILE SOILS

Science has shown that a baby’s exposure to maternal bacterial cultures during natural birth help it to form a healthy, disease-resistant bacterial defense. Likewise, the environmental and soil-based bacteria commonly found in foods grown in fertile organic soils assist in growing and maintaining a healthy makeup of internal flora in humans.

This is the basis of SBO (soil based organism) probiotics like Prescript-Assist.™ SBO probiotics have risen in recognition recently as clinical evidence grows to support their effectiveness. Species from the Bacillus genus, a gut-adapted spore-forming bacteria found in Prescript-Assist, have been demonstrated safe and effective in in vitro and in vivo studies (see Resources section below).

Dr. Mehmet Oz of the Dr. Oz Show says, “Spore form probiotics are the Chuck Norris of probiotics: total tough guys. They have to be to survive splashing around in your stomach’s acid bath. Wimpier types—including live cultures in yogurt—often throw in the towel.”

Among brands of SBO probiotics, Prescript-Assist offers the greatest diversity of species. It is the diversity and the resilience of the Prescript-Assist formulation that accounts for its proven success in peer-reviewed, published clinical trials.

BROAD SPECTRUM DIVERSITY

The Human Microbiome Project (NIH-funded five-years research study by a consortium of nearly 80 universities and institutions) confirmed that the number of microbial species found in the human intestines numbers in the thousands rather than hundreds.

Just as importantly, the project results showed that the distribution of a variety of strains capable of performing similar tasks is more important than the individual species themselves. This information underscores the importance of broad spectrum diversity, and therefore the role that can be played by multi-strain probiotic complexes, such as Prescript-Assist.

microbes over time soil based organisms

Soil based organisms in the human microbiome change during the life cycle.

A review article in Cell refers to the gut as a “natural laboratory for studying the ‘microevolution’ of humans.” The authors write: “In this view, we are seen as superorganisms composed of an amalgam of both microbial and H. sapiens cells, where the survival of microbe and human is interdependent.”

With its balanced formulation of 29 beneficial strains selected to mimic the natural flora found in traditional and paleolithic diets, Prescript-Assist is the only professional-grade probiotic to contain 29 species, 12 different genera, and all four of the most common phyla found in the human digestive tract, including Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria.

soil based organisms human skin

Prevalence on skin sites of different types of bacteria, including soil based organisms.

ADDITIONAL ADVANTAGES OF PRESCRIPT-ASSIST™ PROBIOTIC FORMULA

SHELF STABILITY (NO REFRIGERATION NEEDED)

Prescript-Assist offers exceptional shelf stability. It is well known that conventional probiotics (i.e., lactic acid bacteria) are readily damaged, degraded, and destroyed by heat and pressure during the manufacturing process. They are also degraded by exposure to light and by temperature changes. Because they lack shelf stability, if they are not kept refrigerated, they often cannot provide a sufficient quantity of organisms by the time of ingestion.

In contrast, Prescript-Assist features probiotic bacteria protected by a durable seed-like structure, so that they are better safeguarded against environmental factors, including heat, pressure, light, or temperature variability. Indeed, testing confirms that the probiotic bacteria in Prescript-Assist remain 95% viable two years after their date of manufacture without any need for refrigeration.

PREBIOTIC SUPPORT – LEONARDITE (FULVIC & HUMIC ACIDS)

Most probiotic formulas do not contain any prebiotics, which are a food source for bacteria, and help accelerate their growth. Prescript-Assist uniquely contains Leonardite, which is a prebiotic mixture of humic and fulvic acids, which allows the beneficial bacteria to proliferate and thrive.

Fulvic and humic acids belong to a group of organic substances called humic substances. These are dark brown constituents of humus found in soil that contribute to the character of soil, and are precursors to fossil fuels. They are also found in peat, coal upland streams, dystrophic lakes, and ocean water. Both humic acid and fulvic acid are excellent chelators and powerful antioxidants.

Humic acid is normally found in the form of “humate” (the salt of humic acid), i.e., humic acid bound to a nutritional mineral element. Fulvic acid is normally found in the form of ‘fulvate’ (the salt of fulvic acid), i.e., fulvic acid bound to a nutritional mineral element.

A substantial fraction of the mass of the humic acids is in carboxylic acid functional groups, which endow these molecules with the ability to chelate (bind) positively charged multivalent ions (Mg2+, Ca2+, Fe2+, Fe3+, most other “trace elements” of value to plants, as well as other ions that have no positive biological role, such as Cd2+ and Pb2+).

This chelation of ions is probably the most important role of humic acids with respect to living systems. By chelating the ions, they facilitate the uptake of these ions by several mechanisms, one of which is preventing their precipitation, another appears to be a direct and positive influence on their bioavailability.

Humic acid and fulvic acid have been the subject of many years of scientific study not only because of their role in soil and plant biology, but also with respect to their chelation capabilities. That is, for their proven capacities in removing heavy metals from the human body.

Humic and fulvic acids bind only with double valency positive cations, i.e., nutritional elements and/or heavy metal ions. It is likely that a heavy metal ion will displace a lighter, nutritional metal ion and bind with the humate or fulvate.

Many health care practitioners recommend fulvic acid as an electrolyte (to increase cellular electrical efficiency) and supplement to take in combination with trace mineral supplements in order to assist in their uptake by the body. Fulvic acid bonds with these minerals. Because it is a small molecule and therefore easily able to pass through cell membranes, it allows delivery of the minerals efficiently into cells.

Most products are based on processed humate, taken from high quality soil sources, containing large amounts of nutritional cations already bound into the matrix. They are therefore not likely to deplete an individual’s mineral levels. As fulvic acid/fulvate is the smaller molecule, it is more easily absorbed into the cells. It is regarded as an excellent method of delivery for trace elements and nutrients into the body, as well as being an excellent chelator.

Observed Effects of Humic Acids on Animals

Our focus in this article is upon the effects of soil based organisms and prebiotics (e.g., humic and fulvic acids) in humans. However, it is worth noting that various animal studies show a large number of benefits. These studies show the following benefits:

Covering mucous membrane and adstringent effects

Humic acids can form a protective film on the mucuous epithelium of the gastrointestinal tract against infections and toxins. The macrocolloidal structure of humic acids ensures a good shielding on the mucous membrane of the stomach and gut, the peripheral capillaries, and damaged mucosal cells. As a result of this process, the resorption of toxic metabolites is reduced or fully prevented, especially after infections, in case of residues of harmful substances in foods. Furthermore, humic acids help to prevent excessive loss of water via the intestine.

Antibacterial and virucidal effects

Humic acids can influence the metabolism of proteins and carbonhydrates of microbes by catalytic means. This leads to a directly damaging effect against bacteria or viruses. A second mechanism is related to the interionic bonds of high-molecular protein fractions (toxins) of infectious microbes. Their toxic impact on physiological processes of mucous membrane cells can be weakened considerably or even completely blocked.

Antiphlogical effects

Dermal, oral, or subcutaneous application of humic acids leads to inhibitory effects on inflammation. The ability to inhibit inflammation is considered to be related with the flavonoid groups contained in humic acids.

Antiresorptive and adsorptive effects

As high-molecular humic acids remain in the gastrointestinal tract almost entirely following the enteral application (there is no self-resorption), antiresorptive and adsorptive effects take place where they are needed—in the digestive tract. Primarily cationoid noxes (protein toxins, toxic substances) are fixed, their resorption is reduced considerably or even prevented completely and their elimination through the bowel is promoted. As adsorption by humic acids includes not only physical and chemical reactions, but also complex-formation and ion-exchange, it is more intensive and dynamic compared to purely physical adsorbents.

Effects on the immune system

Humic acids stimulate the resistance forces of the body and lead to an increase in the phagocytosis activity. The inducer effect of phenolic components (groups) of humic acids is believed to be responsible for the immunological effects and is the basis for the success of the treatment of the so-called “factor” diseases in young animals.

Ergotropic effects

Humic acids stabilize the intestinal flora, thereby ensuring improved utilization of nutrients in foods. This leads to an increase in liveweight of the animal without increasing the amount of feed given to the animal.

 

prescript-assist-probiotic-fsmall soil based organisms

Prescript-Assist provides 29 strains of beneficial soil based organisms.

BACKED BY SCIENCE

Probiotic supplement formulas typically do not offer product-specific clinical studies validating their effectiveness. Prescript-Assist™ is different. It is supported by a peer-reviewed, placebo-controlled human clinical trial, and a one-year follow-up study that verifies its long-term efficacy.

Below is a summary of major features and benefits provided by Prescript-Assist™.

SUMMARY OF KEY BENEFITS

  • No Need for Refrigeration.
  • Backed by Sound Science: Supported by peer-reviewed, published clinical studies.
  • Inherent Organism Viability: A matrix of superior, highly resilient microflora whose organic, seed-like structures survive the early GI tract to thrive in the intestines.
  • Contains Bacillus subtilis:  A proven probiotic species found in traditional foods.
  • 29 Symbiotic Organisms: A balanced formulation specially selected to mimic the natural flora found in traditional and paleolithic diets.
  • Proven Shelf Stable:  With variations of less than 5% over two years from date of manufacture when stored at 98°F / 37°C
  • Supported By Prebiotics. Includes Leonardite, a prebiotic mixture of humic and fulvic acids, which allows beneficial bacteria to proliferate and thrive.
  • Gluten-Free, Dairy Free, and Vegan.

DIRECTIONS FOR USE

As a dietary supplement for adults, take 1–2 capsules per day, or as directed by your health care professional. May be taken with or without food.

Storage:

No refrigeration necessary. Store under normal conditions.

Shelf Life:

Routine viability testing confirms greater than 95% viability two years after date of manufacture — without refrigeration. See individual package for expiration dates.

A VIABLE PROBIOTIC FORMULA WITH SOIL BASED ORGANISMS

We at HPDI always strive to bring our customers the best products and formulas available whether or not we ourselves design and produce them.

When the opportunity to carry Prescript-Assist™ arose, we were quick to recognize its many benefits and advantages. We offer this unique formula knowing that it is safe, effective, and can help improve the health of our customers and their patients.

We also know that Prescript-Assist can be used effectively in combination with our other supplements (i.e., HPDI foundational supplements and superfoods), including formulas we design specifically for GI health like Intestinal Rejuvenation Formula.

We take Prescript-Assist™ and experience major health benefits. In addition, we personally witness and hear from many individuals (including health care professionals) who have experienced the benefits of the formula. The results reported are excellent.

It is more important than ever to utilize our current (and rapidly expanding) knowledge about the human microbiome and its constituents to support optimal health and wellness. Science tells us that the human microbiome historically has been populated by a broad range of soil based organisms.

Where we have moved away from nature and traditional agriculture, individuals’ microbiomes can become less vibrant, diverse, and robust. Supplements like Prescript-Assist providing soil based organisms can help bring us closer to having a microbiome more closely resembling our healthy ancestors.

SOURCES AND RESOURCES

BOOKS, ARTICLES & INFORMATION

The Advantages of Soil Based Organisms for Health (from the HPDI blog)

A New View of the Role of Bacteria in Health (from the HPDI blog)

Prescript-Assist™ Broad Spectrum Probiotic & Prebiotic (from the HPDI blog)

Spore Form Probiotics Keep Your Digestive Tract Happy

Body’s Hardworking Microbes Get Some Overdue Respect (Science)

NIH Human Microbiome Project Defines Normal Bacterial Makeup of the Body (NIH)

Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine (Cell)

Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain –for LifeDavid Perlmutter, MD.

SELECTED ABSTRACTS

The Safety of Bacillus subtilis and Bacillus indicus as Food Probiotics (J. Applied Microbiology)

The Safety of Two Bacillus Probiotic Strains for Human Use (Digestive Diseases and Sciences)

PRODUCT INFORMATION

Prescript-Assist™ Probiotic Formula (HPDI website)

Intestinal Rejuvenation Formula (HPDI website)

ADDITIONAL RESOURCES

HPDI BLOG ARTICLES

Contact Us:

You can reach HPDI by calling 1-800-228-4265, email support(at)IntegratedHealth.com, or visit the retail website: www.IntegratedHealth.com

Health care professionals and retailers can apply for wholesale account, which includes access to the HPDI reseller website: www.HealthProductsDistributors.com

2

Warrior Mist™: Creating an Amazing Pain Relief Formula

Dr. Hank Liers, PhD pain relief warrior mistFour years ago I attended a business meeting in which we were discussing the subject of topical pain relief and formulas that could be used for this purpose. We were considering the use of a formula that a local doctor had developed that contained the ingredients dimethylsulfoxide (DMSO), hydrogen peroxide (H2O2), peppermint oil, and dimethylsulfone (MSM). During our discussion when it became clear that the local doctor’s formula would not be made available to our group, I quickly volunteered to develop a topical pain relief formula.

DESIGN CONSIDERATIONS

Over the past twenty years I had formulated and refined several hundred nutritional products, but had not developed a topical pain relief formula. However, in my kitchen research laboratory I had concocted and refined a wide variety of formulas including those for pain relief.

Warrior Mist

Ingredients I had used in developing pain relief formulas include DMSO; chlorella and chlorella growth factor; herbs such as cayenne, aloe vera, arnica, and St. John’s Wort; essential oils such as peppermint (including menthol crystals), wintergreen, lavender, and lemon; the ingredients in Dr. Richard Schulze’s deep tissue massage oil (includes olive oil, wintergreen oil, peppermint oil, cayenne, ginger root, arnica flowers, St. John’s Wort flowers, marigold flowers, and comfrey); coconut oil; MSM; and magnesium chloride.

Before selecting ingredients for the pain relief formula, I established a list of goals for it. I felt the formula should meet these goals:

  • Provide effective temporary pain relief
  • Provide longer lasting pain relief (hours versus minutes)
  • Act fast (should give pain relief within minutes of application)
  • Use natural ingredients
  • Be completely safe (in contrast to many oral pain killers)
  • Smell good
  • Feel pleasant on the skin
  • Exhibit healing qualities regarding the causes of pain
  • Have inherent antimicrobial properties

In addition, I was seeking an ultra low-dose transdermal formula. Transdermal application means the ingredients go directly where they need to go to deal with localized pain. Unlike capsules or tablets, when using transdermal application the ingredients avoid dilution in the digestive tract and processing by the liver, and immediately go to work. Because of the effectiveness of the carrier ingredients and active ingredients, you would need just a few (2–4) drops per use. This means hundreds of applications per one ounce bottle. This means both effectiveness and cost effectiveness!

Ideally, the formula would use a base starting mix of ingredients that function as transdermal carriers and in addition possess a broad range of characteristics (pain killers, antioxidants, oxygen transporters, antiinflammtories, blood flow enhancers, etc.) These could include: 1) dimethylsulfoxide (DMSO), 2) Methylsulfonylmethane (MSM), 3) Ancient Minerals magnesium chloride (hexahydrate) including over 50 trace minerals (found in sea water), 4) Organic extra virgin olive oil (full of antioxidants), 5) Organic coconut oil (a powerful antimicrobial), 6) Aloe vera, and 6) Distilled water.

An interesting thing about this starting mix is that the combination of ingredients are totally compatible with each other which is not obvious initially. For example, DMSO (a liquid) and MSM (a powder) mix well together and have been called an oxygen transport system in the body. Water and DMSO are totally miscible and when mixed together form a eutectic mixture that can substantially lower the freezing point of the ingredients.

The oils in coconut oil also are partially miscible in DMSO and the combination also leads to the depression of the freezing point of the mixture. Oleic acid, the primary ingredient in olive oil is totally miscible in DMSO. Thus it appears that this combination of ingredients could act as an excellent carrier of the active pain killers deeply into the tissues in a local area.

The formula should have essential oils chosen primarily for their affect on pain. These are already considered to be ultra low-dose ingredients in the field of Aromatherapy. In addition, essential oils provide antimicrobial protection to the formula. For example, my initial choice for essential oils in Warrior Mist was peppermint oil (containing about 45% menthol) and lavender oil as pain killers, lemon oil as emulsifier, and all three both as good smelling ingredients and antimicrobials. Interestingly, subsequent microbiological testing has shown that there are absolutely no microbes of any kind in the product.

Initially, I selected chlorella growth factor (CGF) as an additional ingredient that can stimulate healing on a local level using very small amounts. However, due to availability issues with this ingredient, CGF has recently been eliminated from the formula. I chose Ancient Minerals Magnesium Oil as an active ingredient because it provides healing properties at the local level when used transdermally.

I chose not to add Aloe Vera to this formula as it added more volume than wanted and diluted some of the other ingredients. (I did use Aloe vera in my Warrior Energy product that I formulated later in order to reduce the sensation of burning).

THE FORMULA

All of the above ingredients are natural and extremely safe! Below I will discuss each of the included ingredients in some detail.

COMPOSITION / INGREDIENTS: DMSO (99.999% pure), peppermint oil (containing about 45% menthol), organic olive oil, distilled water, MSM, magnesium chloride (hexahydrate), lemon oil, lavender oil, and organic coconut oil.

DMSO Dimethyl sulfoxide (DMSO), a by-product of the wood industry, has been in use as a commercial solvent since 1953. DMSO is found as an ingredient in numerous foods including sauerkraut, tomato paste, milk, beer, coffee, tea and in forage crops such as alfalfa.

Furthermore, in 125 countries throughout the world doctors prescribe it for a variety of issues, including inflammation. DMSO has been used widely as a carrier in topical analgesic formulas. Laboratory studies have shown that DMSO is able to block peripheral nerve C fibers. Burns, cuts, and sprains have been treated with DMSO. Relief is reported to be almost immediate, lasting up to 6 hours. DMSO reduces inflammation by several mechanisms. It is an antioxidant, a scavenger of the free radicals that gather at the site of injury.

Studies have shown DMSO to be one of the safest ingredients known with a toxicity similar to that of water. DMSO has long been used to promote healing both in animals and humans. Those who have used it for minor cuts and burns report that recovery is speedy. Several studies have documented DMSO use with soft tissue damage, local tissue death, skin ulcers, and burns. Applied topically and repeatedly, DMSO flattens the raised, nodular, lobed liner mass of scar tissue in keloids and acne.

MSM MSM is a naturally occurring nutrient found in normal human diets. In the body DMSO and MSM, which form each other, are indistinguishable in their biochemical effects. They reach a equilibrium distribution between them that is dependent on the local body chemistry, and is independent of which one you start with.

The metabolic enhancement mechanism of MSM and DMSO is that of an exceptionally effective oxygen transport system. This system is made particularly effective by the feature that both DMSO and MSM are highly soluble in both oil and water. MSM makes cell walls permeable, allowing water and nutrients to freely flow into cells and allowing wastes and toxins to properly flow out. The body uses MSM along with Vitamin C to create new healthy cells, and MSM provides the flexible bond between the cells. Without proper levels of MSM, our bodies are unable to build healthy cells, and this leads to problems such as lost flexibility, scar tissue, wrinkles, varicose veins, hardened arteries, damaged lung tissues, dry cracking skin, digestive disorders, joint problems, and inability to defend against allergic reactions to food, animals and plants.

The applications of MSM include pain control (analgesic), inflammation control, dilation of blood vessels, increased blood flow, reduced muscle spasm, altering the crosslinking process in collagen (e.g., reducing scar tissue,) anti-parasitic effects (particularly against Giardia), and immune normalizing effects. MSM has a unique ability to pass through cellular membranes (including skin).

Peppermint Oil The primary constituent of peppermint oil is menthol (about 45%), which causes a physical reaction when inhaled or applied to the skin. Menthol produces an immediate and pronounced sensation of coolness that effects the body quite noticeably, and creates a “warming effect” as blood flows into the area of application. In this regard menthol is regarded as a counter-irritant and is an active ingredient approved by FDA in OTC topical analgesic products.

Peppermint oil can be used externally for providing relief from pain. Peppermint oil increases your immunity. It also improves blood circulation. Additional conditions for the use of peppermint oil include: acne, asthma, colds, cramps, dermatitis, exhaustion, influenza, headache, insect bites, mental fatigue, migraine, nausea, nerve pain, neuralgia, poor circulation, and respiratory disorders.

Lavender Oil Lavender oil helps in treating migraines, headaches, anxiety, depression, nervous tension and emotional stress. The refreshing aroma removes nervous exhaustion and restlessness and increases mental activity. Because it induces sleep, it is often recommended for insomnia.

Lavender oil is also an excellent remedy for various types of pains including those caused by sore muscles, tense muscles, muscular aches, rheumatism, sprains, backache, and lumbago. A regular massage with lavender oil provides relief from pain in the joints.

Lavender oil is also good for improving blood circulation in the body. The health benefits of lavender oil for the skin can be attributed to its antiseptic and antifungal properties. It is used to treat various skin conditions, including acne, wrinkles, psoriasis, and other inflammatory conditions. It heals wounds, cuts, burns, and sunburns rapidly because it aids in the formation of scar tissues. It is also effective against insect bites. The oil also repels mosquitoes and moths.

Lemon Oil Lemon oil is powerfully astringent and antiseptic. Lemon oil is detoxifying and is therefore good for blemishes associated with oily skin. Lemon oil is a powerful antioxidant and is a tonic for supporting the nervous and sympathetic nervous system.

It’s been long known that lemon oil is anti-infective, antibacterial (especially with spores), and antiviral. It can function as a disinfectant and exerts vitamin P-like action for improving microcirculation, promotes white blood cell formation, and improves immune function. It has also been widely used in skin care to cleanse skin and reduce wrinkles.

Magnesium Chloride Magnesium chloride (hexahydrate) applied to the skin is an effective means for increasing magnesium levels in the body, and is particularly useful for relieving sore muscles and joints, and reducing pain related to functional magnesium deficiency. It is also proven for use in helping to calm “nerves” and reduce systemic bodily stress.

Because the magnesium targets muscle tissues, it is thereby especially useful for replenishing depleted soft tissues and helping restore proper function. Magnesium is necessary for the production of energy in the body. When the body receives adequate amounts of magnesium, it can produce the levels of energy required to sustain the body and enable it to thrive. Magnesium chloride is proven for use in a variety of general applications, including bruises, cramps, muscle tension, and migraine headaches.

Olive Oil Used as a base and mixed with other essential oils, olive oil makes a wonderful oil for skin health. In fact, it has been touted as one of the oldest healing and beauty techniques. A biblical reference from about 493 BCE documents the daily massage with olive oil and other oils as a part of the beauty regimen.

Coconut Oil Coconut oil is a superb skin lotion because it both nourishes skin and is naturally anti-bacterial, antiviral, and antifungal due to its high content of medium chain triglycerides.

OUR EXPERIENCES

The first batch of Warrior Mist was made by me in my kitchen in May of 2011 using ingredients I had on hand, weighed out using a microbalance I owned, and combined in a small glass jar.

My partners and I tested the mixture and found that it worked well as a pain killer. I was able to source all of the ingredients rather quickly and soon found a company willing to produce and bottle the formula.

We produced our first batch in August 2011 and began selling the product in amber glass dropper bottles at Kiosks in shopping malls. We found that the results obtained for pain relief were exactly what we were hoping for – fast acting (usually within a few minutes), long lasting (up to 8 hours), and widely applicable to many different types of pain.

We also discovered that Warrior Mist had no side effects. None of the ingredients in Warrior Mist are known to have any side effects in regular use, especially at the lower dosages made possible through transdermal use.

Soon we were selling Warrior Mist at sporting events such as marathons and triathlons. Users were getting amazing results and testimonials were flooding in. We quickly realized that we had a very special product on our hands and moved quickly to make it broadly available through radio and TV ads.

Warrior Mist

TESTIMONIALS

One of our earliest and most amazing testimonials for Warrior Mist is given below:

1-WM.Test.Mercer

Another early testimonial that gave us a clue as to just how effective Warrior Mist is:

“I admit to being very skeptical, however, a few minutes after applying Warrior Mist to my hands and wrists, the pain was gone! Shocking! Nothing, and I seriously mean nothing, had ever worked before. Now I can drive without pain, type without pain, do housework without pain, garden without pain, and do household repairs without pain. I’ve suffered from devastating chronic pain for 35 years. My life had become so limited. Warrior Mist will not only help me, but my husband will also be unburdened from having to do everything for me!”
Laura C., PhD/PH

Here is a testimonial from a person who manufactures Warrior Mist for us:

I have been using Warrior Mist for over a year now and it has been truly a God send. I use the Mist for my migraines and my back. I have a slipped disk and when I do certain things to irritate it, it is like disturbing a bee’s nest. I have been in bed for two days now and the only thing that alleviates the pain enough for me to stay comfortable is the Warrior Mist. I just wanted to take the time to thank you for creating this wonderful product.
Kellie K.

Here’s a representative testimonial from an online buyer:

I recently purchased the Warrior Mist Pain Reliever and found that it works great. The nice thing about this product is that it has a very pleaseant smell and doesn’t leave you feeling like your wearing a pain relieving product. Putting this product on and then going to bed really helps with a good nights sleep as I used to wake up half way through the night in pain again.
Kimberly S.

Here’s another testimonial from an online buyer:

As a retired police detective with 32 years on the job I have a lot of aches and pains in every joint in my body. My wife and I have tried every external pain reliever on the market with little to no results. My order came yesterday so I tried it on my wife who has some nerve pain in her upper back. Within 15 minutes she told me her back actually felt better. I had her put it on my lower back – always hurts after a work out. Almost instantly my back did not hurt and during the night it felt like I had an ice pack on my back.
Alan K.

Here’s a testimonial from an athlete:

I was about to compete in a race and sprained my ankle two days before. I had a cortisone shot and it didn’t work at all. I tried Warrior Mist and got instant and total relief! I was able to run the race. Great stuff!”
Jill P.,

My partner, Herb, has applied Warrior Mist to thousands of people at Kiosks, Rock & Roll Marathons, TriAthlete Events, and State Fairs. He has told me that frequently (many hundreds of times!!!) when someone came to him in pain and he convinced them to try it out, the typical reaction within just a few minutes of applying it is “It can’t be! – my pain is gone! – I don’t believe this!”

HOW TO MAXIMIZE THE EFFECTIVENESS OF WARRIOR MIST

Warrior Mist LLC personnel have helped thousands of people in pain apply Warrior Mist on painful areas of their bodies. In about 99% of these cases people have experienced major pain relief within minutes. While doing this we have learned much about how to apply Warrior Mist in different pain situations in order to get the maximum benefit.

Our experience has shown us that surrounding the pain gives a superior results. By this we mean that whenever possible Warrior Mist should be applied above, below, to the sides, and behind the painful areas. The discussion below regarding a range of pain conditions gives further insight into what we mean by surrounding the pain.

Plantar FasciitisApply Warrior Mist to the area giving you pain, generally speaking where the heel meets the arch of your foot, but also surround the pain by applying it around the area and on top of the foot as well.

Knee PainMost of the time we find that sufferers feel the pain on the front of the knee or side (like a torn meniscus). Of course apply the Warrior Mist there, but we have found that surrounding the pain by applying on the back of the knee makes the pain simply disappear.

Lower Back PainSurround the pain. This means that most folks feel lower back pain in a specific spot, like the base of the spine in the lumbar. Apply Warrior Mist there of course, but also apply it across the width of the entire lower back to relieve the pain and reduce spasms that may be occurring.

SciaticaCharacterized by shooting pains down the leg, it is really important to use Warrior Mist at the root of the pain, the lower back. Apply on the lumbar, then to the side where the pain is shooting towards. It is usually unnecessary to apply Warrior Mist down the leg as this is referred pain from the lower back.

Headacheheadaches come in many forms and most folks mislabel them. Migraine is a common term but usually what we see when people come up to us at an event and complain of having a migraine it is either a tension related headache or one related to neck pain. True migraines are usually marked by seeing lines or squiggles and nausea including vomiting. If you suffer from true migraines, Warrior Mist can help if you get it on early enough, but in all honesty if you don’t the pain may be so intense that a prescription medication or injection might be in order. For the vast majority though, Warrior Mist will reduce or eliminate pain if used properly. As we always say, surround the pain. Apply to the back of the neck, behind the ears, and the temples. Relief should come on fast!

Shin SplintsSurround the pain by applying to the front of the leg, the shin itself, but also a bit behind the leg on the calf.

Restless Leg SyndromeWe have two suggestions to surround the pain and stop RLS from keeping you awake all night long. First, apply Warrior Mist directly to any pain or itching areas of your leg. Second, always apply it behind the knee as well. Customers tell us that this does the trick and they sleep all night long.

Neck PainThis one is easy; make sure you surround the pain by treating the entire back of your neck and not just one little area that hurts. Lots of neck pain is referred, meaning that you feel it in one place but it is coming from another. Also, always treat the neck when you are treating shoulder pain as well. Lots of that is referred as well.

Shoulder PainShoulder pain is hard to pinpoint because there are so many tendons, muscles, and ligaments in the shoulder. If you have a specific injury caused by, say throwing a baseball or lifting weights, then treat and surround the affected area. But, if you woke up one day and your shoulder started hurting for no apparent reason, treat the neck and then down the length of the shoulder including the rotator cuff.

Tennis/Golfers’ ElbowSurround the pain and apply Warrior Mist on the entire circumference of the elbow, inside and out to make sure to erase the pain!

Carpal Tunnel SyndromeSurround the pain by applying Warrior Mist to the carpal tunnel area itself and then around the circumference of the wrist front and back.

Hand Pain and Lack of MobilitySurround the pain by applying a few drops of Warrior Mist to the palm of your hand and the rubbing it all over both hands front and back much like old time movie and cartoon villains did. Think Snidely Whiplash in old Dudley Doright cartoon. Your hands are going to feel great in a minute and have greatly increased mobility!

Skin ConditionsThese are pretty easy to treat. Just apply Warrior Mist directly to the site of the irritation. Now, being realistic, look for immediate relief from the itching and pain, but the actual irritation make take some time and repeated applications to completely clear up. It varies from person to person.

ToothacheTip the bottle of Warrior Mist with your hand over the applicator and put one drop on the tip of your finger. Then, rub it around the base of the tooth and gum and feel the immediate relief. Oh, and it is going to taste very minty but not sweet. The taste will disappear in a minute or so but the relief will last for hours. Please remember, Warrior Mist does not cure dental disease. It is meant to relieve pain while you are waiting for an appointment with a dentist.

CONCLUSION

As can be seen from the testimonials and as we know from our firsthand experience, Warrior Mist is an amazingly effective topical pain relief formula. To me it is gratifying that I was able to meet all of my design goals for the product and that it has helped so many people deal with their pain.