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MYO-MAG MAGNESIUM & MALIC ACID – ENERGIZING FORMULA

Dr. Hank Liers, PhD myo-mag magnesium malic acid energizing formulaFred Liers PhD myo-mag magnesium malic acid energizing supplement

Got energy? That’s a big question. Many people are low on energy. A major cause of low energy is magnesium deficiency. In fact, studies show 50%–90% of people are deficient, often highly deficient. Magnesium boosts energy levels by feeding the body’s energy production system or Krebs cycle.

Myo-Mag— HPDI’s magnesium and malic acid formula — is designed to supercharge your energy production system to support a high energy lifestyle. Are you ready for what Myo-Mag can do for your energy? Well, it boosts energy, but does a lot more, too!

Getting enough magnesium is critical, of course. But it is equally important to get readily assimilable forms of magnesium and the synergistic nutrients required for its uptake and utilization. Myo-Mag provides optimal forms of magnesium and synergistic nutrients required to create energy (as ATP) for higher energy living. Myo-Mag feeds the body’s energy production system (Krebs cycle), which maximizes cellular energy. That is why users of Myo-Mag report far greater energy levels.

⚡ MYO-MAG FOR ENERGY – AND MUCH MORE ⚡

Myo-Mag supplies critical nutrients for energy production (as ATP) in the body. But it offers benefits far beyond boosting energy levels. Being a super magnesium formula, Myo-Mag optimizes all other beneficial effects of magnesium. In addition to energy production, magnesium is essential for muscle health, cardiovascular health, balancing calcium levels (and ensuring proper calcium uptake), as well as for proper function of more than 800 enzyme systems in the body.

⚡ MYO-MAG BENEFITS ⚡

ENERGYMyo-Mag supplies your cellular energy system with raw materials it can use immediately to produce energy for high vitality living. Myo-Mag can help you create energy fast—and naturally!

• MENTAL ENERGY – Just as Myo-Mag boosts physical energy, it can also boost mental energy. The energizing forms of magnesium and synergistic nutrients it provides create cellular energy the body can use for all purposes requiring energy.

MUSCLE RECOVERYMyo-Mag supports muscle health, muscle use, and muscle recovery. You might call Myo-Mag a muscle formula, and indeed “Myo” means “muscle” in Greek. Muscles that are properly nourished function well and are loose, not contracted, overly tight, or cramped. Muscles can benefit from Myo-Mag!

RELAXATION AND CALMING – In addition to being an “energy” production formula, Myo-Mag provides forms of magnesium and other nutrients that allow the body to relax. Muscle relaxation is a well known effect of magnesium. Also, the counterbalancing effect of magnesium on calcium in cells contributes to a relaxation effect. Too much calcium by itself (without being balanced) by magnesium can lead to muscle contraction and tension.

• GREATER SENSE OF WELL-BEINGMyo-Mag can provide an overall sense of well being. This is likely due both to the wide range of benefits and effects of magnesium (see list below) combined with the benefits of the synergistic nutrients it provides. For example, a combination of the known benefits of muscle relaxation, improved mood, and increased vitality can together contribute to an overall increased sense of well-being.

• CARDIOVASCULAR HEALTH – The heart is a muscle and gain major benefits from the right forms of magnesium, like other muscles

• HEADACHES – The ingredients in Myo-Mag are known to help headaches, including migraine headaches

• MANY OTHER BENEFITS – Due to its status as an exceptional magnesium & malic acid formula, Myo-Mag provides all benefits associated with magnesium (see list below), but also supercharges these benefits due to the malic acid (malate), B vitamins, and other synergistic nutrients.

myo-mag magnesium malic acid energizing formula

⚡ MYO-MAG OVERVIEW ⚡

Myo-Mag is an advanced magnesium formula that supports metabolism, energy production (ATP), and optimal cellular function. It allows for rapid uptake and absorption of easily assimilated forms of magnesium. It also provides critical nutrients supporting energy production in the body. Because Myo-Mag rapidly boosts magnesium levels, individuals usually notice greater physical and mental energy, reduced fatigue, and often a greater sense of overall well being.

⚡ MAGNESIUM, MALIC ACID (MALATE), B VITAMINS, AND MORE ⚡

Myo-Mag contains ingredients participating in the production of ATP. One vegetarian capsule contains 100 mg of magnesium and over 300 mg of malic acid. Vitamin B1 is included as Thiamin HCl and vitamin B2 is included as both Riboflavin and Riboflavin 5′-phosphate. Also included are vitamin B6 in its pyridoxal 5′-phosphated coenzyme form, manganese (because high levels of magnesium can deplete the body of it), magnesium carbonate (a malic acid buffer), and glycine as the carrier for a portion of the magnesium and for the manganese.

Supplementing the diet with magnesium and malic acid may reverse conditions of low energy. Suggested daily amounts include 300–600 mg of magnesium and 1200–2400 mg of malic acid.

⚡ MYO-MAG CONSIDERATIONS & APPLICATIONS ⚡

There are several key nutrients needed by mitochondria to manufacture ATP in the body. These include oxygen, magnesium, food substrate, ADP, and inorganic phosphate, as well as Vitamin B1, Vitamin B2, and Vitamin B6 in their phosphorylated (coenzyme) forms.

The body also requires malate (an important Krebs cycle intermediate) in order for most of these nutrients to function effectively in the process of ATP production. When adequate amounts of any of these nutrients are not present in the mitochondria, a vicious cycle can occur in which ATP is not created in amounts sufficient for proper cell function.

Insufficient amounts of ATP means that some B vitamins may not be adequately phosphorylated leading to improper metabolism and further reductions in ATP production. The much less efficient anaerobic production of ATP may be utilized to a greater extent. A balance point may be reached wherein the body produces only a fraction of the optimal amount of ATP. Under these conditions muscle weakness and fatigue may occur.

Vitamin B6 in its coenzyme form (pyridoxal-5’-phosphate) and magnesium are required for normal activity of malate dehydrogenase enzymes  involved in ATP production in the Krebs Cycle. In addition, the respiratory chain involved in ATP synthesis requires adequate amounts of the coenzyme  forms of B vitamins B1 and B2, which are the precursors of NAD and FAD. These two B vitamins, like B6, require a magnesium-dependent phosphate transfer reaction to become biologically active. Magnesium deficiency would therefore create a sluggish respiratory chain and a decreased efficiency in the transfer of reducing equivalents from the cytosol to the mitochondria. Supplementing the diet with magnesium and malic acid boosts energy production and thereby can reverse conditions of low energy.

In “Management of Fibromyalgia: Rationale for the Use of Magnesium and Malic Acid,” Abraham and Flechas reported that supplementing the diet with magnesium and malic acid may reverse such conditions of low energy (Jrnl of Nutritional Medicine 1992 3: 49–59). The recommended daily amounts include 300–600 mg of magnesium and 1200–2400 mg of malic acid.

⚡ MAGNESIUM ⚡

Magnesium is a key ingredient in Myo-Mag which provides 100 mg per capsule in the form of magnesium malate. Magnesium plays a major role in energy production in the body. In particular, magnesium plays a critical role in key enzymatic reactions  for both aerobic and anaerobic glycolysis, which is the oxygen-dependent metabolic pathway that coverts glucose in to energy at ATP and NADH.

In order to appreciate the many benefits Myo-Mag offers, it helps to understand the effects and benefits of magnesium. Magnesium levels influence many physiological processes and functions. These include:

• Increases energy by greater production of ATP (adenosine triphosphate) in cells
• Supports production and function of over 800 enzyme systems in the body
• Relaxes muscles / reduces muscle tension
• Boosts vitality, endurance, and strength
• Improves cardiovascular / heart health (relaxes cardiac muscle)
• Relieves pain, including chronic pain
• Ideal for arthritis / fibromyalgia / joint pain
• Improves health of skin and mucous membranes
• Eases headaches and migraine headaches
• In sports medicine — replenishes Mg levels for energy (combats fatigue, and
soothes pain and sore muscles)
• Improves mood and reduces stress
• Increases memory and cognitive functions
• Boosts immune system
• Improves assimilation of calcium / builds stronger bones
• Balances calcium and magnesium levels in cells
• Proven antimicrobial and antiseptic
• Raises DHEA (dehydroepiandrosterone) levels naturally
• Eases menopause and premenstrual syndrome (pms)
• Supports healthy libido (and endocrine system)
• Anti-aging, rejuvenating, revitalizing
• Keeps cell membranes flexible
• Controls cholesterol production in the body
• Regulates blood sugar levels / needed for insulin production, transport, and
function in cells
• Supports antioxidant systems
Given the wide range of benefits conferred by magnesium on the human body, it becomes apparent that no level of deficiency is acceptable. Magnesium is simply critical for life and for health. It is far better to have more magnesium than less.
MYO-MAG contains three types of magnesium: magnesium malate, magnesium carbonate, and magnesium diglycinate. As noted, the malate form of magnesium offers the unique benefit of feeding the energy production system in the body. The magnesium carbonate in the formula acts as a buffering agent while magnesium glycinate is absorbed into the bloodstream thereby increasing absorption beyond the gastrointestinal tract.

⚡ MALIC ACID / MALATE ⚡

Myo-Mag provides malic acid via magnesium malate, which breaks down in the body into about 80% malic acid and 15% magnesium. Malic acid is a compound (molecular formula C4H6O5made by all living organisms. Malic acid contributes to the sour taste of fruits, and its name derives from the Latin word for apple. Esters and salts of malic acid are known as malates. The malate anion is an intermediate in the citric acid cycle, or Krebs cycle, which produced energy (ATP) in the body.
According to Abraham and Flechas (1992): “Malate is the only metabolite of the citric acid cycle which correlates positively with physical activity.” They add: “Following endurance training of athletes, muscles were characterized by a 50% increase in the malate-aspartate redox shuttle enzymes, where malate plays a key role…When there is increased demand for ATP, there is also an increased demand and utilization of malate.”

⚡ MANGANESE ⚡

Myo-Mag includes manganese because high levels of magnesium can deplete manganese. The classes of enzymes that have manganese cofactors is large and includes oxidoreductases, transferases, hydrolases, lyases, isomerases, ligases, lectins, and integrins. The reverse transcriptases of many retroviruses (though not lentiviruses such as HIV) contain manganese. The best-known manganese-containing polypeptides may be arginase and Mn-containing superoxide dismutase (Mn-SOD)

Manganese is an essential human dietary element. It is present as a coenzyme in several biological processes, which include macronutrient metabolism, bone formation, and free radical defense systems. It is a critical component in dozens of proteins and enzymes. The human body contains about 12 mg of manganese, mostly in the bones. The soft tissue remainder is concentrated in the liver and kidneys. In the human brain, the manganese is bound to manganese metalloproteins, most notably glutamine synthetase in astrocytes.

⚡ MYO-MAG USAGE ⚡

Taking 1–3+ Myo-Mag provide nutrients that help the body create energy. However, taking 3–6 (or more) Myo-Mag daily would meet the need for supplementing with 300–600 mg of magnesium and 1200–2400 mg of malic acid that is known to reverse conditions of low energy. We recommend starting low (1-2 capsules) and then gradually increasing the dosage. Myo-Mag is contained in a vegetarian capsule to ensure rapid assimilation.

COMPOSITION: One (1) vegetarian capsule of Myo-Mag provides the following percentages of the Daily Value:

NUTRIENT AMOUNT % Daily Value
Magnesium (Mg malate, diglycinate, carbonate) 100 mg 24%
Malic Acid (Mg malate)
300 mg *
Manganese (Mn diglycinate) 5 mg 217%
Vitamin B1 (Thiamin HCl) 10 mg 633%
Vitamin B2 (Riboflavin) 8 mg 615%
Vitamin B2 (Riboflavin-5′-phosphate) 2 mg 154%
Vitamin B6 (Pyridoxal-5′-phosphate) 5 mg 294%
Glycine (Mg and Mn diglycinate) 160 mg *

* No established Daily Value

DIRECTIONS: As a dietary supplement take 1–3+ capsules daily, or as directed by a health care professional.

INGREDIENTS: MYO-MAG only contains the highest-quality USP grade magnesium malate, magnesium diglycinate, magnesium carbonate, manganese diglycinate, thiamin HCl, riboflavin, pyridoxal-5′-phosphate, riboflavin-5′-phosphate, vegetable cellulose (capsule), microcrystalline cellulose, and silica.

MYO-MAG does not contain wheat, rye, oats, corn, barley, gluten, soy, egg, dairy, yeast, sugar, GMOs, sulfates, chlorides, wax, preservatives, colorings, or artificial flavorings.

⚡ CONCLUSION ⚡

Energy is important for life and health. And whether you realize it or not, large numbers of factors—some of which are beyond your control—conspire daily to rob you of energy. These factors may include low magnesium levels, stress to EMF exposure (like Wi-Fi or cell phone radiation), adverse dietary influences (like glyphosate/RoundUp), other chemical and/or environmental exposures, and even just lack of exercise. One of the easiest things to do is to take Myo-Mag to get the magnesium, malic acid, and synergistic nutrients you need to build greater energy levels. Get ready to blast off! ⚡

 

⚡ MYO-MAG RESOURCES ⚡

Myo-Mag Magnesium & Malic Acid Formula

HPDI Mineral Formulas

Myo-Mag on Amazon

HPDI Blog Articles

The Health Benefits of Oral Magnesium Using Myo-Mag by Dr. Hank Liers

Articles

Uses and Benefits of Magnesium Glycinate

Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection
(J Parenter Enteral Nutr Sep-Oct 1994;18(5):430-5.)

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MIGHTY MULTI-VITE! MULTIVITAMIN – UPDATE

Dr. Hank Liers, PhD mighty multi vite multivitamin supplementFred Liers PhD Hank Brian mighty multi vite multivitamin

Think you take a complete multivitamin? Well, maybe not. Typical multivitamins simply do not provide enough nutrients for optimal health. Or for that matter, the proper forms and carriers of nutrients to do the job right—the all important task of providing you with essential nutrients for health. Not so easy these days? Well, Hank & Brian’s Mighty Multi-Vite! can help—a lot!

MIGHTY MULTI-VITE! DEFINES A COMPLETE MULTIVITAMIN

The task of providing you with a complete set of nutrients—as easily absorbed forms—is where Hank & Brian’s Mighty Multi-Vite! shines brightly in the world of #multivitamins. Quite simply, Dr. Hank Liers carefully formulated Mighty Multi-Vite! as the most advanced, complete multivitamin available. It uniquely includes a wide range of vitamins, minerals, cofactors, herbs, antioxidants, and Nrf2 activators (nutrients that allow your body to make its own antioxidants). This wide range of nutrients alone puts Mighty Multi-Vite! in a class by itself.

Calling HPDI’s Mighty Multi-Vite! “complete” is an understatement. While other multivitamins may contain more ingredients, Dr. Hank’s goal is not to “stuff” as many ingredients (or amounts) into Mighty Multi-Vite! as possible. That is a “shotgun” approach—Dr. Hank avoids it—that often results in too large capsules, huge tablets (“horse pills”), or eight-per-day dosages that are hard to consume—and even harder to stick with over time. You get the idea.

Instead, Dr. Hank carefully designed Mighty Multi-Vite! to include both a broad range of essential nutrients and abundant amounts of the most important nutrients for health in easily to assimilate forms using multiple carriers that give the body choices. For example, the body requires far smaller amounts of coenzyme B vitamins (which are the  natural forms best utilized by cells) than conventional forms of B vitamins. This allows for more efficient dosing and does not “waste” space in the capsule allowing more room for other nutrients, like antioxidants and Nrf2 activators. In a nutshell, few multivitamins are so well balanced and designed carefully to give the body what it needs for optimal health. You get it all in just four (4) regular size capsules, daily. How easy is that?

As I mentioned, Mighty Multi-Vite! includes highly absorbable forms of nutrients. These include mineral carriers like Krebs Cycle bionutrients—carriers that feed the energy producing system in the body—including malates, ascorbates, aspartates, sebacates, citrates, and glycinates. Thus, we use magnesium malate, and calcium ascorbate and citrate. The whole point is that the body immediately recognizes and utilizes these forms.

In practice, Dr. Hank’s inclusion of the most absorbable forms and carriers means you actually absorb and assimilate more of the ingredients—whether vitamins, minerals, cofactors, antioxidants, herbs, or Nrf2 activators—than you would from the same old conventional forms and carriers (oxides, for example) found in many multivitamins, especially “off-the-shelf” or “one-a-day” type formulas. Many so-called “boutique” formulas use conventional forms and carriers. Who knew!?

To top it off, many advanced ingredients in Mighty Multi-Vite! (like Nrf2 activators) are nowhere to be found in the vast majority of multivitamins. You might not even know to look for them!

However, the biggest benefit of the science behind Mighty Multi-Vite! is how you feel when taking it. I really feel the difference. Your multivitamin should work for you and support your best health. If your multivitamin is not giving you what you need—or you can’t feel the difference it makes in your life—then why take it? Maybe it is better than nothing, but why settle for less when better options are available?

The single biggest reason I am a huge fan of Mighty Multi-Vite! is because I have taken it for more than 20 years. I have gained all the benefits it offers—for thousands of days—year after year. I am more than confident in its superior benefits not just for me, but because I have seen many other people gain benefits, and heard countless positive testimonies from happy customers. I know you can gain major benefits from it, too.

But wait, there’s more! Read the overview (below) for some nitty, gritty details distinguishing Dr. Hank’s design of Mighty Multi-Vite!. These not-so-little details can make all the difference for your good health.Mighty Multi-Vite multivitamin supplement

MIGHTY MULTI-VITE! OVERVIEW

COMPLETE, BALANCED ESSENTIAL NUTRITION – Provides a full spectrum of nutrients exceptionally well balanced for creating and maintaining optimal heatlh. Mighty Multi-Vite! offers all of the most important vitamins along with minerals, cofactors, antioxidants, herbs, and Nrf2 activators.

RAPID, EASY ASSIMILATION – Incorporates the most bioavailable vitamin and mineral carriers most easily recognized and rapidly assimilated by your body. In addition, the formula uses multiple forms of mineral carriers to ensure assimilation. In addition, the capsule form (compared to tablets) speeds uptake because it does not require time for the body to break it down.

ENERGIZING – Includes coenzyme form vitamins and Krebs Cycle bionutrients that work with your body to create super high energy levels. Provides significantly higher levels of B vitamins than most multivitamins (especially coenzyme B vitamins). These vitamins are known for boosting energy, supporting the body during times of stress, and supporting nerve, heart, brain and immune system function.

FEATURES & BENEFITS OF MIGHTY MULTI-VITE! MULTIVITAMIN

• A full-spectrum of B-complex vitamins, most in coenzyme forms, as well as more conventional forms. Includes Vitamin B1 as thiamin HCl, Vitamin B2 as riboflavin and riboflavin-5’-phosphate, Vitamin B3 as niacinamide and niacin, Vitamin B5 as pantothenic acid, Vitamin B6 as pyridoxine HCl and pyridoxal-5’-phosphate, folate as L-5-methyltetrahydrofolate calcium (L-5-MTHF), Vitamin B12 as methylcobalamin, and biotin

• All of the most absorbable and usable forms of the fat-soluble vitamin group, including Vitamin A (as alpha & beta-carotene), Vitamin E (as d-alpha tocopherol succinate), Vitamin D3 (as cholecalciferol), and Vitamin K (as phytonadione (K1) and MK-7 (menaquinone-7) (K2))

• A complete and balanced supply of the most abundant carotenoids found in the body, including beta-carotene, alpha-carotene, lycopene and lutein

• A variety of the best-known herbal preparations, including whole grape extract (seeds, pulp, skin), turmeric (95% curcuminoids), broccoli sprouts powder, and octacosanol (from rice bran)

• All of the known essential minerals in forms readily absorbed and recognized by the body including calcium, magnesium, potassium, zinc, manganese, boron, copper, chromium, molybdenum, vanadium, and selenium

• Mineral carriers such as ascorbates, Krebs cycle bionutrients, and amino acids providing the body with important metabolic substrates and vitamins, including citrate, succinate, malate, glycinate, aspartate, sebacate, and Vitamin C

• Contains a wide range of antioxidants and Nrf2 activators including Buffered Vitamin C, Vitamin A, Vitamin E, Carotenoids, NAC, whole grape extract, curcuminoids, and broccoli sprouts

• Includes N-Acetyl-L-Cysteine (NAC), an important sulfur-containing amino acid supporting the body’s antioxidant and detoxification systems, and betaine HCl to support digestive processes

• Includes Choline and inositol which play a crucial role in all the cell membranes of the body, in brain function, and in liver function

• Includes Nrf2 transcription factor activators (i.e., Nrf2 activators), which are nutrients that direct cells to produce their own antioxidants, making your body an antioxidant production machine. Most multivitamins contain few, if any Nrf2 activators. Mighty Multi-Vite! is one of the few multivitamins whose design intentionally provides Nrf2 activators.

• Exclusion of the prooxidant minerals of iron and iodine which can lead to excessive free-radical production and PABA that sometimes adversely affects brain function in some individuals. (Note: we sell iodine formulas separately.)

• Capsule form ensures maximum absorption of ingredients

• Four-per-day full dosage allows for partial dosing for children, seniors, and pets

• Vegetarian formula (including capsule) suitable for vegetarians and vegans

• Exclusion of ingredients such as wheat, dairy, corn, soy, gluten, and egg having well-known antigenic properties and that may be associated with allergy or delayed hypersensitivity reactions

• A minimum of excipients, fillers, lubricants, etc. having deleterious effects in some individuals

• NON-GMO (no genetically modified organisms)

CONSIDER MIGHTY MULTI-VITE!

Most people don’t think too hard about their multivitamins. They focus on taking the supplement de jour (whatever supplements make headlines) or continue taking the same one-a-day multivitamin.

That is too bad because a multivitamin truly is the single most important nutritional supplement. We at HPDI place the multivitamin first—above all other supplements—in importance. Our Foundational Supplements system starts with a multivitamin because it is the only formula designed to provide the basic nutrients essential for health. That is, you can add other essential nutrients (like vitamin C or essential fats) to complete your regimen. But the multivitamin remains king (or queen) because it establishes your baseline nutrient intake. That is something is to consider when selecting the multivitamin you will take daily for the rest of your life.

Ask yourself: Is my multivitamin complete, providing all the most important nutrients I need for health? Is it easily absorbed using multiple, readily assimilated forms and usable carriers of those nutrients? Is it proven to work? Is it easy to take? Do I notice the effects?

If you answer “no” to any of these questions, or if you simply never think about it, then consider Hank & Brian’s Mighty Multi-Vite!. You should love your multivitamin because of how it supports your health. We think you will love Mighty Multi-Vite!.

MIGHTY MULTI-VITE! RESOURCES

Hank & Brian’s Mighty Multi-Vite!

HPDI Multivitamins

Foundational Supplements

VIDEOS

HPDI YouTube Channel

Foundational Supplements video

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ULTIMATE PROTECTOR+ BRUNSWICK LABS ORAC6.0 TEST REPORT

Dr. Hank Liers, PhDHPDI’s new product ULTIMATE PROTECTOR+ is a next generation cell protection formula that simultaneously meets the needs for high levels of Vitamin C, full spectrum antioxidants* (high ORAC values), and protective enzyme activators (Nrf2 activators from plant-based polyphenols) in a single product. This potent combination of characteristics distinguishes the formula because no other single product available today offers such complete protection.

All three of ULTIMATE PROTECTOR+‘s components provide significant protection against the various types of free radicals that cause cellular damage in the body. In particular, the full spectrum of antioxidants derived from high ORAC fruits, vegetables, and herbs (as well as Vitamin C) provide extremely powerful exogenous sources of protection against oxidative stress. To obtain a quantitative measure of just how powerful these external sources are we have elected to conduct ORAC testing.

ORAC TESTS

ORAC (standing for “Oxygen Radical Absorption Capacity”) was developed by Brunswick Labs as an analytical tool for estimating the antioxidant capacity of substances. It is an in vitro test that was an important advancement in commercially available analysis of the peroxyl free-radical’s trapping ability of foods and ingredients. It has become a de facto standard in the natural products industry. However, the original ORAC method was considered to be just a starting point for comprehensive antioxidant analysis.

The fact is that there are a variety of “free radicals” that operate in humans — the most important of which are the primary radicals hydroxyl, peroxyl, peroxynitrite, singlet oxygen, and superoxide anion. Brunswick Labs has reported that even though the peroxyl is the major free radical in the body, it represents no more than 27% of the total antioxidant potential of selected fruits and vegetables. In addition, the original ORAC method favors certain antioxidant substances over others (e.g., anthocyanins over carotenoids) due to the use of a single free radical source (peroxyl radical).

These radicals are formed, behave, and are defended against differently. They all contribute to: 1) a general condition called “oxidative stress,” or cellular damage, and 2) broad human health concerns caused, for example, by inflammation, and DNA and protein damage. They are each implicated in different health problems – from cardiovascular disease to macular degeneration and Alzheimer’s disease and to skin damage and aging. Below we provide a brief summary of these free radicals.

The Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification. Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes (such as SOD and glutathione). It can damage virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure. Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.

Singlet Oxygen is generated in the skin by by UV. In vivo, it is linked to the oxidation of LDL cholesterol and cardiovascular disease. Singlet oxygen is highly unstable and durable. Carotenoids are very effective at scavenging singlet oxygen. Superoxide Anion is a precursor of all other reactive oxygen species and sometimes is referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage. Antioxidants that scavenge superoxide anion also help prevent the formation of radicals such as hydrogen peroxide and hydroxyl. Superoxide anion has been linked to hypertension and cardiovascular damage.

Recently, Brunswick Labs has introduced a new test called ORAC6.0. This test expands the ORAC platform to measure the antioxidant capacity against each of the five primary reactive oxygen species mentioned above as well as Hypochlorite (HOCl) which is another important free radical that is commonly found in the body as a by-product of the metabolism of other free radicals. Direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions. ORAC6.0 substantially improves broad-spectrum antioxidant analysis and gives evidence of the diverse antioxidant potential of natural products against radicals other than just peroxyl.  Brunswick Labs’ research shows that the antioxidants found in a wide range of natural products are effective against these primary radicals, and that in many cases a preponderance of a product’s antioxidant capacity is described by performance against the six free radicals included to the ORAC6.0 panel.

RESULTS OF ULTIMATE PROTECTOR+ ORAC6.0 TEST

Recently [August/2019] Brunswick Labs has tested ULTIMATE PROTECTOR+™ using the new ORAC6.0 tests. The results reveal an incredible overall ORAC6.0 value of 272,743 µmole TE/gram (i.e., 272,743 per gram!). In addition, the results show that the formula offers excellent protection against all of the six types of free radicals. Specifically, the results show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of ULTIMATE PROTECTOR+™ containing 3.55 grams of the formula.

The overall daily ORAC6.0™ value for six capsules  obtained by adding the values for each free radical type is 968,237 units (272,743 units x 3.55 g)! To the best of our knowledge there is no other product that even comes close to providing such complete protection both in terms of breadth of coverage and overall strength. The Brunswick Labs ORAC6.0™ test results for ULTIMATE PROTECTOR+™ are posted on our blog.


Ultimate Protector+ nrf2 activator formula

 

The bottom line is that you (or anyone) can stand to benefit dramatically from an advanced antioxidant formula that provides exceedingly high ORAC6.0 values and hence amazingly high cell protection…with just a modest daily dose of six small capsules. If you are at all interested to see how well this formula can protect your heath, then we suggest you try a bottle. See for yourself how ULTIMATE PROTECTOR+™ acts to provide you with the ultimate level of protection against free radicals. It’s 100% guaranteed.

ULTIMATE PROTECTOR+™ ORAC6.0 Units Per Serving (six capsules)

ORAC6.0 Units
Per Serving*

Free Radical Type
11,985 Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification.
19,770 Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes. It damages virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure.
9,791 Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.
121,300 Singlet Oxygen is generated in the skin by UV exposure. It is linked to the oxidation of LDL cholesterol and cardiovascular disease.
787,624 Superoxide Anion is a precursor of all other reactive oxygen species – sometimes referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage.

17,768

Hypochlorite HOCl – direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions.

968,237

Total ORAC6.0 Per Daily Serving of Six Capsules (3.55 g)

View the Brunswick Labs Ultimate Protector™ ORAC6.0 Test Report Here

 

ULTIMATE PROTECTOR+™ contains USP-grade non-GMO Vitamin C, SFB® standardized fruit blend (~50% polyphenols, high-ORAC powder: 9,000 µmole TE/g) from Grape, Cranberry, Pomegranate, Blueberry, Apple, Mangosteen, Bilberry, Chokeberry, and Goji Berry), Curcumin (standardized extract with 95% curcuminoids), Trans-Resveratrol (98% from Giant Knotweed), Green Tea Extract (93% polyphenols, 50% EGCG), VinCare® Whole Grape Extract (>80% polyphenols, ORAC>19,000 µmole TE/g), Calcium Malate, Magnesium Malate, and Bioperine® (a patented black pepper extract that enhances absorption of all ingredients and is a known Nrf2 activator).

* Full-spectrum antioxidants in Ultimate Protector+ include polyphenols, flavonoids, anthocyanidins, oligomeric proanthocyanidins, catechins, curcuminoids, ellagic acid, pterostilbene, resveratrol, chlorogenic acid, xanthines, punicalagins, quercetin, zeaxanthin, carotenoids, polysaccharides, quinic acid, and others.

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What I’d Really Love to Tell You About the Methylation Cycle

Dr. Hank Liers, PhD geneticsI previously published “Homocysteine Genetics – Coenzyme B Vitamins” in which I considered in-depth how homocysteine (an intermediate chemical in the Methylation Cycle) is formed from methionine, how genetics affects the metabolic pathways, and how B vitamins are used in metabolic pathways. I also wrote “Folate Ingredients – Folinic Acid & 5-MTHF” which discussed how coenzyme folate vitamins are far superior to the synthetic folic acid form. In today’s article, I take a broader view of the topic that encompasses the Methylation Cycle, genetics, and B vitamins.

THE METHYLATION CYCLE

The Methylation Cycle is considered to be one of the most important metabolic pathways in the human body. Its most important function is to provide methyl groups via SAM (S-adenosyl methionine) to hundreds of different body substrates. Methylation is continually occurring in the body, transforming many millions of molecules throughout the body every second. Molecules receive methyl groups, then separate and recombine continuously, transforming and reforming constantly in the ongoing process of life!

As a reminder of the pathways involved in the Methylation Cycle, the following figure provides a flow chart showing the details.

 

Methylation Cycle

Figure 1. Metabolic Pathways in Methylation Cycle

A key purpose of this cycle is to provide methyl groups (CH3) needed by a broad range of of body functions (over 200 different functions). Examples include:

  1. Influences the genetic expression that parents give their children and helps guide the development of the embryo.
  2. Is needed by the nervous system to produce neurotransmitters and maintain the nerves.
  3. Mobilizes fats and cholesterol so they do not accumulate where they are harmful, such as the arteries and liver.
  4. Regulates hormones, including, estrogen, adrenaline, and melatonin.
  5. Detoxifies harmful chemicals and histamine a prime substance involved in inflammation.
  6. Helps repair damaged proteins in the cells so they can function properly.
  7. Protects the DNA in the genome (genetic code) to reduce the chances of mutation.
  8. Creates antioxidants used in the antioxidant defense system.

DESCRIPTION OF PATHWAYS WITHIN THE METHYLATION CYCLE

The overall flow of the Methylation Cycle begins with dietary methionine (an essential amino acid) which combines with ATP (adenosine triphosphate – body energy) to form SAM (S-adenosyl methionine) – the common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. When SAM transfers a methyl group to a body chemical the residue from this reaction leads to the production of homocysteine.

Homocysteine can be converted in the transsulfuration pathway that requires coenzyme vitamin B6 to produce cysteine, glutathione, taurine, and sulfates. These sulfur containing substances provide important antioxidant protection and detoxification functions in the body.

Homocysteine can be converted back to methionine through the betaine (trimethyl glycine) pathway which requires zinc and magnesium. This pathway also requires dietary betaine or choline which the body can convert into betaine.

Also, homocysteine can be converted back to methionine via the remethylation pathway which requires 5-MTHF, coenzyme vitamin B2 and methylcobalamin (B12).

GENETICS

It is important to understand that each of the pathways described above are able to be executed only in the presence of enzymes (shown in blue boxes in the diagram) created by specific genes in your genetic code. For example, Betaine-Homocysteine S-Methyltransferase (BHMT) is the enzyme required in the betaine pathway, Cystathione Beta Synthase (CBS) is the enzyme required in the transsulfuration pathway, and Methylenetetrahydrofolate Reductase (MTHFR) and Methionine Synthase (MS) are enzymes required in the remethylation pathway.

Assuming that you have perfect genetics (no mutations, SNPs, free radical damage, insertions/deletions, etc.), the proper functioning of these pathways are still subjected to the fact that the required vitamins and minerals (vitamin B6, vitamin B2, Folate, vitamin B12, zinc, magnesium, and betaine) need to be provided by your diet or from supplements for the body to function correctly.

In addition, exposure to high levels of toxins from your environment and high levels of stress require that the nutritional needs will be even higher for the pathways to work properly. For example, exposure to high levels of toxins requires that the transsulfuration pathway be more active possibly reducing the amount of available methionine to support necessary methyl transfer reactions.

For these reasons alone the consensus of knowledgeable practitioners is that you should be eating an organic whole foods diet, taking appropriate nutritional supplements, avoiding and eliminating toxins from food, water, and air (living in a clean environment), and avoiding an unduly stressful life. All of these actions fall into the category of Epigenetics which you generally have control over!! Doing these things alone could significantly balance the functioning of your Methylation Cycle and improve your health.

Unfortunately, few people have perfect genetics which often causes the various pathways in the Methylation Cycle to become imbalanced and unable to correct the dysregulation imposed upon the body. For example, the enzyme MTHFR can have heterozygous (single chromosome) genetic variations in up to 50% of certain populations and homozygous genetic variations (both chromosomes) in 10% or more of certain populations.

Some disorders that researchers have associated with MTHFR genetic variations include:

  • Alzheimer’s disease
  • Asthma
  • Atherosclerosis
  • Autism
  • Bipolar disorder
  • Bladder issues
  • Blood clots
  • Breast problems
  • Chemical sensitivity
  • Chronic fatigue syndrome
  • Down syndrome
  • Epilepsy
  • Fibromyalgia
  • Gastric problems
  • Glaucoma
  • Heart murmurs
  • High blood pressure
  • Irritable bowel syndrome
  • Leukemia
  • Male infertility
  • Methotrexate toxicity
  • Migraines with aura
  • Multiple sclerosis
  • Myocardial infarction
  • Nitrous oxide toxicity
  • Parkinson’s disease
  • Pulmonary embolisms
  • Schizophrenia
  • Stroke
  • Thyroid issues
  • Unexplained neurologic disease
  • Vascular dementia

This extensive list is highly significant and tells us that it is very important to have genetic testing done for the genes/enzymes in the Methylation Cycle pathway. I prefer the BodySync genetic test which evaluates the key Methylation Cycle genes plus many other important genes in a single test.

B VITAMINS AND MINERALS

We are strong believers that everyone should start their nutritional program by eating a balanced, organic, whole foods diet. We have been doing this ourselves for the past 30 years. Unfortunately, only a small percentage of people follow this advice and in most cases this leads to poor nutritional status that does not adequately support the body’s needs. This is especially true with respect to obtaining the nutrients needed to support the Methylation Cycle.

Nine of our family members and associates have taken the BodySync genetic test which evaluates the condition of 45 different enzymes including CBS, MTHFR (2 variations), MTR (related to B12 and 5-MTHF as they relate to methionine synthase – MS), and MTRR (related to maintaining B12 levels needed by the MTR enzyme). In every case the results showed at least 2 and up to 4 enzymes had genetic variations. These results indicate that the nutritional requirements for folate as 5-MTHF, vitamin B12 as methylcobalamin, vitamin B6, vitamin B2, magnesium and zinc will likely be significantly greater than normal.

Given the above information, it seems essential for good health to take nutritional supplements that provide the important nutrients. Below I will discuss various formulas that I have developed and refined over many years that are useful especially for the Methylation Cycle.

Please note that Health Products Distributors, Inc. (HPDI) is the preferred supplier of nutritional supplements by the BodySync genetic testing company.

MULTIVITAMINS

When looking at the total needs the body has for nutrients that the body does not produce, including fat soluble vitamins (A, D (some), E, K1 and K2), vitamin C, B vitamins (B1, B2, B3, B5, B6, folate, B12, biotin, choline, and inositol), minerals (Ca, Mg, Zn, Se, Cu, Mn, Cr, Mo, K, boron, and vanadium), and betaine it only seems wise to include as a top priority a Multivitamin that includes all of these in what I term therapeutic amounts (carefully selected after evaluating thousands of research studies carried out over many years.)

In this context, it is important to recognize that every enzymatic reaction in the body requires mineral cofactors in order to carry out its function. A good multivitamin provides many of these required minerals.

Additionally, the multivitamin should contain ingredient forms that research has confirmed to be the most absorbable and usable by the body. These include coenzyme B vitamins, Krebs cycle (citrate, alpha-ketoglutarate, succinate, fumarate, & malate) minerals, and amino acid chelates.

In the context of supporting the Methylation Cycle we are looking for specific forms and amounts of B vitamins that can adequately provide the body’s needs. The means that there should be coenzyme folate as 5-MTHF of at least 400 mcg, coenzyme vitamin B-12 as methylcobalamin of at least 200 mcg, Vitamin B6 (including significant amounts of pyridoxal 5′ phosphate) of at least 40 mg, and Vitamin B2 (including significant amounts of riboflavin 5′ phosphate) of at least 25 mg. In addition, magnesium (100 mg) and zinc (at least 20 mg) should be provided.

Please note that the body’s requirements for magnesium is generally accepted by nutritional experts to be higher than 400 mg daily (and as high as 1,000 mg daily). For this reason we generally recommend that a person take supplemental magnesium (such as HPDI’s MYO-MAG) at levels over 400 mg daily.

The two multivitamin formulas Health Products Distributors provides for adults that meet these requirements (and more) are the Hank & Brian’s Mighty Multi-Vite and Multi Two (in both capsule and tablet forms). Click on the bottles below for technical details.

Hank & Brian's Mighty Multi-Vite multivitamin methylation cycle

Multi Two Caps or Tablets methylation cycle

B COMPLEX

In situations where significant genetic variations are present it may be wise to add a B COMPLEX supplement to the MULTIVITAMIN to provide even larger amounts of the needed B vitamins. HPDI provides a B-Complex-50 product that includes significant amounts of coenzyme forms and contains 50 mg of Vitamin B1, 50 mg of Vitamin B2, 100 mg of Vitamin B3, 50 mg of Vitamin B6, 500 mcg of coenzyme folate (both folinic acid and 5-MTHF), 100 mcg of B12 (both methylcobalamin and hydroxocobalmin), 50 mg of Vitamin B5 (pantothenic acid), 500 mg of Biotin, 50 mg of choline, and 50 mg of inositol. Click on the bottle below for technical details.

B-Complex-50 full spectrum B vitamins with coenzyme forms methylation cycle

FOLATE AS 5-MTHF

In situations where an inadequate diet is present and genetic testing indicates an MTHFR variation (especially a homozygous variation) Health Products Distributors provides a 5-MTHF folate supplement that easily absorbs into the body and can be directly used in combination with Vitamin B12 to convert homocysteine to methionine. Click on the bottle below for technical details.

5-MTHF 1 mg in veggie cap methylation cycle

5-MTHF 1 mg in veggie cap

B-12 as METHYLCOBALAMIN

It is often the case for older patients and vegetarians that Vitamin B12 is deficient. In these cases it is wise to supplement with a significant amount of methylcobalamin to ensure that the Methylation Cycle has sufficient to effectively convert homocysteine into methionine. Health Products Distributors Vitamin B12 contains 5 mg of methylcobalamin in sublingual lozenge form that supports excellent absorption even if swallowed and absorbed by diffusion. Click on the bottle below for technical details.

Vitamin B-12 5 mg methylcobalamin sublingual lozenge methylation cycle

Vitamin B-12 – 5 mg Methylcobalamin sublingual lozenge.

MINERALS

Magnesium and zinc are two important minerals used in the betaine pathway of the Methylation Cycle in which homocysteine is converted back to methionine.

In the body magnesium is involved in more than 400 essential metabolic reactions and is required by the adenosine triphosphate (ATP)-synthesizing protein in mitochondria. ATP, the molecule that provides energy for almost all metabolic processes, exists primarily as a complex with magnesium (MgATP). Therefore, it also is involved in converting methionine to SAM.

Over 300 different enzymes depend on zinc for their ability to catalyze vital chemical reactions. Zinc-dependent enzymes can be found in all known classes of enzymes.

Health Products Distributors provides 100 mg magnesium/vcap in its MYO-MAG supplement which is especially important in increasing ATP in the Krebs Cycle. This product also contains vitamin B1, vitamin B2, and vitamin B6 with substantial amounts of coenzyme forms and manganese. Click on the bottle below for technical details.

MYO-MAG with 100 mg magnesium per serving key B vitamins methylation cycle

MYO-MAG with 100 mg magnesium per serving and key B vitamins.

Health Products Distributors provides 25 mg zinc/serving in its Double Zinc Plus supplement. This formula provides zinc in the picolinate and citrate forms as well as 3 mg of P5P (coenzyme B6). Click on the bottle below for technical details.

Double Zinc Plus supplement with P5P and 25 mg zinc methylation cycle

Double Zinc Plus supplement with P5P and 25 mg zinc

SUMMARY

The Methylation Cycle is recognized as one of the most important metabolic pathways in the human body. When not properly supported by key B vitamins and minerals, the Methylation Cycle can become severely imbalanced which can lead to a very wide range of poor health conditions. Furthermore, genetic variations in the genes that produce important enzymes allowing the Methylation Cycle to function correctly lead to even further imbalances and greater possibility for conditions of poor health.

In this article, I have provided insight into how the Methylation Cycle works and how it can be significantly supported by lifestyle changes regarding diet and environment (Epigenetics) and by specific B vitamins and mineral supplements that I have developed over many years. In addition, we have shown that knowledge gained from genetic testing can further provide a critical understanding of your specific needs so that your health can be optimized.

RELATED HPDI BLOG ARTICLES

Homocysteine Genetics – Coenzyme B Vitamins

 

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BONE FRACTURES SUPPORT

Dr. Hank Liers, PhD bone fracturesSeveral years ago a customer asked me for a program that could be helpful to those suffering with bone fractures. A relative had been diagnosed with multiple bone fractures in his ankle.

Since I have been counseling individuals regarding natural treatments for supporting those with bone fractures and injury for many years, I was able to provide a comprehensive program that could be helpful in recovery. More recently, we have introduced products and tools that can be even more supportive. Therefore, in this article we are providing an update to the bone fractures program.

Clearly, the need for such a program is great. According to the American Academy of Orthopaedic Surgeons (AAOS), about six million individuals suffer fractures each year in North America. In about 5–10 percent of cases, patients suffer either delayed healing or fractures that do not heal.

The problem of bone fractures is especially troubling for the elderly, many of whom suffer from osteoporosis, a condition in which bones become weak and break more easily. For an older person, a fracture affects quality of life because it significantly reduces function and mobility, and requires an extended period of recuperation.

The bone fracture program set forth below also works well to support the healing of other types of bone problems, including broken bones, bone surgery, osteoporosis, and wisdom tooth removal.

THE BONE FRACTURE PROGRAM

IMPORTANCE OF FOUNDATIONAL SUPPLEMENTS

The first element of the program consists of Foundational Supplements. This group of supplements ensures the body is being supplied with all of the basic elements needed for optimal function. The primary foundational supplements consists of 1) a therapeutic multivitamin and mineral formula, 2) a complete buffered Vitamin C with antioxidants formula, 3) an essential fatty acids supplement, and 4) a high-RNA superfoods formula.

Our Foundational Supplements are described in great detail on the HPDI website where we provide a free downloadable e-book “The Need for Foundational Supplements” (.pdf). Suffice it to say that the foundational supplements are a essential part of the program that ensure healing will take place quickly and effectively. I encourage everyone to become familiar with this information as foundational supplements are basic to any wellness or healing program.

bone fractures

ENHANCEMENT FORMULAS ARE CRITICAL FOR HEALING BONE FRACTURES

The second element of the program for healing bone fractures consists of Enhancement Formulas that strengthen the body as it relates to dealing with the damaging effects of bone fractures. These include a Vitamin D3 formula with the synergistic nutrients of Vitamin A and Vitamin K2 that are required for the rebuilding of bone as well as strengthening the body in many other ways. The HPDI Vitamin D3 Plus formula to designed to specifically address this need.

A second Enhancement Formula in this program is our comprehensive Bone Guardian formula that is based upon micronized veal bone that provides hydroxyapatite (Ca10(PO4)6(OH)2). Hydroxyapatite is the basic component of human bone that is 50% by volume and 70% by weight. Whereas the Vitamin D3 Plus formula builds the bone matrix, the Bone Guardian fills in the matrix with materials such as calcium, phosphorus, magnesium, boron, zinc, manganese, copper, silica, and strontium. HPDI sells Bone Guardian in both the tablet and capsule forms. The capsule form may be better for older people who are able to absorb capsules better than tablets.

A third Enhancement Formula to the program is additional amounts of Vitamin C. Vitamin C is known to participate in every step of the process of building collagen, which is a key component of bone. Vitamin C has been shown to increase bone mass density. We recommend slowly increasing your intake of buffered Vitamin C until you reach your bowel tolerance. This can be accomplished by increasing your intake of HPDI’s foundational supplement PRO-C™ formula. The PRO-C has the added value of containing oligomeric proanthocyanidins (OPCs) from grape seed, skin, & pulp. OPCs in the body are able to strongly crosslink and strengthen new and damaged collagen fibers needed needed to repair bones, ligaments, tendons, and cartilage.

SPECIFIC CONDITION FORMULAS TARGET BONE FRACTURES

The third element in the program are Specific Condition Formulas that directly address issues related to bone fractures. The first of these is the addition of a joint formula that allows the body to build and repair connective tissue and to significantly reduce inflammation in the area of bone fractures. In most cases of fractures there will be damaged ligaments and tendons as well as inflammation in the area.

HPDI’s Joint Health Formula includes the ingredients glucosamine hydrochloride, MSM, and sea cucumber (a significant source of chondroiten sulfate) in addition to anti-inflammatory substances such as turmeric extract, rutin, and grape extract (seed, pulp, and skin) that have been extremely helpful in both repairing connective tissue and reducing pain and inflammation.

A second strongly recommended condition-specific formula is proteolytic enzymes. Because it is highly likely in the case of bone fractures and injury that there is significant tissue damage, a formula with pancreatic and plant enzymes as well as anti-inflammatories can be extremely helpful is clearing out the damaged tissue. This gives the body the opportunity to begin the rebuilding process much sooner.

Our recommended PROLYT formula contains the proteolytic enzymes bromelain, trypsin (pancreatic enzyme), and chymotrypsin (pancreatic enzyme), and the polyphenols/bioflavonoids turmeric extract (95% curcuminoids), quercetin and oligomeric proanthocyanidins (OPCs) from grape extract. This formula when taken on an empty stomach between meals is quickly absorbed into the bloodstream and goes to work cleaning up any damaged tissues in the area surrounding a fracture and assists in reducing pain and inflammation.

TOPICAL MAGNESIUM CHLORIDE FOR PAIN AND RAPID HEALING

A final Specific Condition Formula that I highly recommend for healing bone fractures is to rub Ancient Minerals Magnesium Oil on and surrounding the fracture area. Bones cannot heal without having adequate amounts of magnesium available. Unfortunately, many people are deficient in magnesium and even taking oral magnesium cannot easily provide sufficient amounts to an area with a bone fracture. Magnesium oil (mostly magnesium chloride) is quickly absorbed transdermally (via skin) and often can provide rapid healing and pain relief!

BODY pH COULD BE A FACTOR IN HEALING BONE FRACTURES

The processed food diets with a high protein and low vegetable content consumed by many people in the U.S. and elsewhere often produce conditions in the body of acidity. This in turn leads to decreased oxygenation of cells and encourages a greater amount of anaerobic processes in metabolism. In addition, when the body is acidic calcium can be taken from bones in order to balance the acidity. This can lead to poor healing of bone fractures.

In order to counter acidic conditions in the body we recommend the use of HPDI’s pH ADJUST formula. As a dietary supplement, take 1 gm (about a rounded ¼ tsp) in 4-8 ounces of purified water preferably away from food, or as directed by a health care professional.  For extremely acidic conditions, try 4–10 doses per day, depending on acidity level. Use pH paper to ensure pH levels remain balanced, and do not become too alkaline (alkalosis may occur above pH 8.2).

TESTING pH LEVELS: The best way to test pH levels is to use litmus paper, which HPDI offers in rolls (Hydrion brand) for this purpose. You can test salivary or urinary pH. In order to test salivary pH, simply use a small strip of pH paper to dip into a small amount of saliva. Advantages of pH paper include rapid results, ease of use, and cost effectiveness.

pH Paper bone fractures protocol

The color of the litmus paper indicates the pH level of the body fluid tested. Most litmus paper comes with an indicator chart showing colors corresponding to various pH levels. Alkaline states will generally produce a dark green, blue or purple color (most basic). Acidic states will range from yellow (most acidic) to light green.

Salivary pH and urinary pH are significantly affected by recent food consumption and other factors, so it it best to test pH hours after meals or in the morning when you awake. We prefer to measure urinary pH since results are more consistent. Measuring urinary pH is a simple as placing a few drops of urine on the paper or dipping the paper into a sample cup of fresh urine.

A consistent pH measurement of less than 7.0 indicates that you are too acidic (values less than 6.2 show extreme acidity). This indicates that you should consume more alkaline forming foods (usually vegetables) and/or take pH ADJUST. A single dose of pH ADJUST can change conditions in the body from acidic to alkaline within a few hours.

GENETIC VARIATIONS IN YOUR VITAMIN D RECEPTOR GENE (VDR) MAY BE AN IMPORTANT FACTOR

The VDR gene (contained in every cell of the body) provides instructions for making a protein called vitamin D receptor (VDR), which allows the body to respond appropriately to vitamin D. This vitamin can be acquired from foods in the diet or made in the body by exposure to from sunlight. Vitamin D is involved in maintaining the proper balance of several minerals in the body, including calcium and phosphate, which are essential for the normal formation of bones and teeth. One of vitamin D’s major roles is to control the absorption of calcium and phosphate from the intestines into the bloodstream. Vitamin D is also involved in several process unrelated to bone formation.

VDR attaches (binds) to the active form of vitamin D, known as calcitriol. Calcitrol is produced in the body from Vitamin D3 (cholecalciferol) in the liver and kidneys. The interaction with calcitriol allows VDR to partner with another protein called retinoid X receptor (RXR). The resulting complex of proteins then binds to particular regions of DNA, known as vitamin D response elements, and regulates the activity of vitamin D-responsive genes. By turning these genes on or off, VDR helps control calcium and phosphate absorption and other processes.

In recent years, genetic tests have become available that show VDR variations can cause serious conditions related to low bone density and other important body functions such a higher blood glucose levels or lower immune system function. If a person is having little success in healing bone fractures, it is possible that VDR variations are a key factor of causation.

In such cases, we recommend having genetic testing done to determine if VDR variations are present. Recently, HPDI has teamed with a genetic testing company (BodySync, Inc.) and sells the BodySync test kits on our Reseller site. Please click here to see our blog article regarding the BodySync genetic test. Among the genes tested for in the test are three variations of the VDR gene. Resellers can purchase the test kits directly from HPDI and retail customers can call us  (800-228-4265) to find out how we can help them get a test kit and support them with any associated counseling regarding the results.

SUGGESTED SUPPLEMENT SCHEDULE – BONE FRACTURES

I have included all of the above supplements including recommended dosages plus more related to having an excellent diet in the table provided below.

Description AM Noon PM Night Comments
PRO-C 2 caps 2 caps 2 caps Take with meals or with snack.
Bone Guardian 

Bone Guardian Caps (easier to absorb)

3 tabs

3 caps

 

3 caps

3 tabs

3 caps

Take with meals.

Take with meals.

Mighty Multi-Vite! or
Multi Two — Multivitamins
2 caps or
1 tab
2 caps or
1 tab
Take with meals.
Essential Fats plus E 2 softgel 2 softgel 2 softgel Take with meals.
PROLYT – Proteolytic Enzyme Formula 2 caps 2 caps 2 caps 2 caps Take between meals.
Buffered Vitamin C, Tablets — 1,000 mg (1 gm) or Powder (1/4 tsp = 1 gm) 2 tabs or
1/2 tsp
2 tabs or
1/2 tsp
2 tabs or 1/2 tsp 2 tabs or 1/2 tsp Best with meals, but other times are okay. Start with 2 tabs or 1/2 tsp twice per day and add another 2 tabs or 1/2 tsp every few days until you are taking 8 tabs or 2 tsp per day.
Vitamin D3 Plus 5,000 IU 1 softgel 1 softgel Take with meals. Reduce to 1 softgel after 2 months.
Joint Health Formula 2 caps 2 caps 2 caps Take between meals and away from Bone Guardian.
Magnesium Oil 10 pumps 10 pumps 10 pumps 10 pumps Spray on affected area – or nearby area.
Rejuvenate! Plus or
Rejuvenate! (original)
1 scoop 1 scoop Take as a meal by itself or with fruit/berries.

ADDITIONAL NUTRIENTS FOR BONE FRACTURES

Additional nutrients that may be helpful include pH ADJUST (to balance excess acidity in the body),  Warrior Mist™ for pain relief (rub on adjacent area several times daily), Echinacea (as drops or capsules), N-Acetyl-L-Cysteine – NAC (2 gms per day), Progesterone Cream – for women (1/4–1/2 tsp twice daily), and TerraFlora probiotics/prebiotics (2 capsules daily) if on antibiotics.

PROPER DIET IS ESSENTIAL

Consume a diet that provides good amounts of protein which is needed by the body to support the healing of bone fractures. Eat meats, poultry and fish (e.g., sardines, salmon, mackerel) in the amount of a 5–10 ounces per day. Ensure a good intake of organic vegetables, including high levels of dietary fiber. Drink 16 oz per day of fresh vegetable juices from carrot, celery, beets, cabbage, etc.

Other healthy foods (preferably organic) include fruits, whole grains (e.g., brown rice, millet, and quinoa), beans, nuts and seeds (sunflower, chia, flax, pumpkin, almond, walnut and sesame in small amounts — 2 or 4 ounces — are good). Try eating Hank’s Vegetable Soup several times a week. Avoid all sweets (sugar), processed/refined foods (white bread and pasta), preservatives, and artificial flavors and colors. Vary your diet.

HYDROTHERAPY (WATER THERAPY) FOR BONE FRACTURES

An additional treatment that can be useful is hydrotherapy. In particular, hot and cold showers are a very effective way to move the blood and create circulation. This can speed up both detoxification and delivery of healing nutrients to the area of a bone fracture. Here’s how to do this. Once daily, take a complete hot and cold shower. You will start with hot water for one minute, then cold for one minute. Repeat this seven (7) times so the shower should last about 15 minutes.

Another time, daily, you can perform a complete hot and cold shower routine again or a partial one just applying the water directly to or near the area where there is a bone fracture. While you are doing both hot and cold showers, pay special attention to any affected area and massage it as vigorously as is safe and comfortable. If a shower is impossible, then alternate hot packs and ice packs on the area of the bone fracture.

BONE FRACTURES – CONCLUSION

By following the recommendations and suggested supplement schedule, healing time for bone fractures can be significantly reduced and fractures may heal more completely with fewer complications. By ensuring your body receives the proper nutrients it needs to heal itself, and by engaging in other relevant practices (e.g., hydrotherapy), you and/or your loved ones may be able to deal with bone fractures successfully, and continue a healthy, vibrant lifestyle.

ADDITIONAL RESOURCES

HPDI REJUVENATION PROGRAM

REJUVENATION PROGRAM PART 6 (INCLUDES HYDROTHERAPY)

REJUVENATE!™ SUPERFOODS

ULTIMATE PROTECTOR™

“FRED’S FAVORITE VEGETABLE JUICE RECIPE: ‘THE DOCTOR'”