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REJUVENATE! BERRIES & HERBS – INGREDIENTS FOR OPTIMAL NUTRITION

Fred Liers PhD rejuvenate! berries & herbs superfoodI write a lot about superfood ingredients, and especially those in HPDI’s Rejuvenate! superfoods. One superfood I write about less often is Rejuvenate! Berries & Herbs.

This may relate to the fact that Rejuvenate! Original and Rejuvenate! PLUS provide plenty of greens like chlorella and spirulina. Greens make these superfoods popular, and it is easy educating health care professionals and consumers alike on their benefits.

Rejuvenate! Berries & Herbs is different. It provides ultra-high ORAC value (14,200+) per serving. It also provides more dietary nucleic acids (390 mg) per serving than other Rejuvenate! superfoods. It tastes so good it may the HPDI’s best-tasting superfood. Even Health Ranger Mike Adams loves it, and stocks it in his online store.

Rejuvenate! Berries & Herbs superfood

Rejuvenate! Berries & Herbs is one of three HPDI superfoods providing dietary nucleic acids.

REJUVENATE! BERRIES & HERBS IS DIFFERENT: IT LACKS GREENS

But it lacks greens. And greens are what almost everyone wants. As noted, Rejuvenate! Original and PLUS formulas provide high levels of greens like chlorella and spirulina. Berries & Herbs provides none.

For some people, no greens is just great. We developed Berries & Herbs because we want to offer one superfood with high levels of dietary nucleic acids that does NOT contain greens.

Formulating a high-RNA superfood without greens is an admirable goal. Most of the dietary nucleic acids in Rejuvenate! superfoods (and dietary RNA is what makes HPDI superfoods unique) come from greens. For example, chlorella contains amazingly high levels of nucleic acids, more than any other ingredient.

THE VERSATILE, NON-GREEN SUPERFOOD WITH NUCLEIC ACIDS

Rejuvenate! Berries & Herbs was created as superfood lacking greens. It suits its purpose because: 1) certain individuals cannot stomach greens like chlorella; 2) many people enjoy greens, but also desire variety; 3) many prefer a fruity, berry-flavored superfood for reasons of taste–and Berries & Herbs tastes delicious.

While the lack of greens could be perceived as a liability, it is one of the greatest benefits of Rejuvenate! Berries & Herbs.

rejuvenate! berries & herbs superfood greens continuum

Rejuvenate! Berries & Herbs is the HPDI superfood without greens.

In this article, I want to recap the benefits of Berries & Herbs and present some new information on ingredients, characteristics, and qualities of this unique, non-green superfood.

GREENS ARE GREAT, BUT SO ARE “BERRIES & HERBS”

First, I haven’t written an article about Berries & Herbs since February 2014 when I published “Be Healthy with Rejuvenate! Berries & Herbs.” That was an in-depth piece. And the information is still 100% true: I favor greens, as in greens provided by Rejuvenate! Original (greens) and Rejuvenate! PLUS (sweet greens).

One major difference: while I consume plenty of greens those green Rejuvenate! superfoods, there is now more room in my diet for non-green superfoods. That means Berries & Herbs.

I already take 5–10 servings per day of Rejuvenate! Original. That may sound like a lot, but I reduce my food intake to accommodate higher levels of superfoods. I feel satisfied with reduced food intake when consuming higher levels of superfoods.

As a result, my dietary nucleic acid intake is quite high. High levels of dietary nucleic acids are part of what make Rejuvenate! superfoods unique. High-purity and nutrient density are other major benefits.

I probably do not require more dietary nucleic acids (unlike athletes like pro cyclist Irena Ossola whose training and performance benefit from higher levels of dietary RNA). I already get sufficient RNA.

However, there are many reasons I consume Rejuvenate! Berries & Herbs:

 Berries & Herbs can be more filling than Rejuvenate! Original. Therefore it makes a nutritious breakfast drink, or after breakfast power booster.

• Contains a full-spectrum multivitamin. It doesn’t replace my daily multivitamin (Hank & Brian’s Mighty Multi-Vite!), but it does give me an extra boost of vitamins/minerals in liquid form (smoothie, blender drink, or plain in almond milk, juice, or water).

• Tastes amazingly good. That means it makes a delicious and healthy “refresher”  or “snack” between meals. It also makes a great after dinner “dessert” drink.

• Makes yummy shakes of whatever consistency you like. You can use less liquid (or more Berries & Herbs) for a thicker shake. Add a drop or two of stevia if you desire a sweeter taste.

• Tasty replacement for drinks like hot cocoa, tea, or coffee.

• Blends well with milks, yogurt/kefir, nut milks, and herbal teas.

• Great addition to foods, including fruit, berries, granola, and grains.

• Nutritious when used as an ingredient in homemade bars (see bar recipes).

• Delicious in plain water and without added sweeteners.

• Kids love Berries & Herbs. It can be added to drinks and foods as a healthy booster. Since my son loves Berries & Herbs, I use it in his drinks and foods.

These are just a few of the advantages of Berries & Herbs that I know from personal experience, and from talking to many people who use it regularly.

rejuvenate! berries & herbs superfood

MORE THAN MEETS THE EYE: EIGHT BENEFITS OF BERRIES & HERBS

There’s a lot more to Rejuvenate! Berries and Herbs that you might guess. I identified eight key benefits of Berries & Herbs in my previous post. A few of these benefits overlap with those I mention (above) as reasons I consume Berries & Herbs. But most of the eight benefits are unique:

1) TASTES GREAT

2) HIGHER RNA LEVELS THAN OTHER REJUVENATE!™ SUPERFOODS

3) CELL-SUPPORTING HERBS FOR OPTIMAL HEALTH

4) SLOWER DETOXIFICATION FOR A GENTLER DETOX EXPERIENCE

5) HIGH PROTEIN (ALL VEGETARIAN)

6) MULTIVITAMIN WITH COENZYME B COMPLEX FOR ADDITIONAL NUTRIENTS

7) HIGH ANTIOXIDANT VALUE (14,200+ ORAC) FOR REJUVENATING POWER

8) NRF2 ACTIVATORS SUPPORT ANTIOXIDANT PRODUCTION IN CELLS

These eight benefits create a profile of advantages specific to Berries & Herbs. I will discuss most of these benefits below.

HIGH LEVELS OF DIETARY NUCLEIC ACIDS (RNA, DNA)

Before I talk about how good Berries & Herbs tastes (and did I mention it tastes really good?), I want to present information about dietary nucleic acids.

Dietary nucleic acids are so important for health that Dr. Benjamin S. Frank devoted his entire life to studying them. He declared them to be “essential nutrients” for health like vitamins and minerals.

One way dietary nucleic acids (RNA, DNA) support health is by boosting production of energy (ATP) in the body. When ATP production is high, the body has sufficient energy to support many of the biological functions required for keeping you healthy.

Read more about health benefits of dietary nucleic acids in my article, “9 Things to Know About Rejuvenate! Superfoods” and other blog articles.

Inspired by Dr. Frank’s scientific writings, my father Dr. Hank Liers formulated the series of Rejuvenate! superfoods specifically with the idea of providing high levels of dietary nucleic acids (RNA, DNA) to support optimal health. All three Rejuvenate! superfoods provide at least 340 mg of dietary nucleic acids.

To be exact, Rejuvenate! (Original) and Rejuvenate! PLUS both provide 340 mg of dietary nucleic acids per serving. Rejuvenate! Berries & Herbs provides a whopping 390 mg of dietary nucleic acids!

That’s 50 mg more dietary nucleic acids per serving. As I noted, an extra 50 mg of dietary nucleic acids (Rejuvenate Berries & Herbs compared to other Rejuvenate! superfoods) may not seem like much, yet those servings add up.

At one serving daily, in a single week you will consume an “extra” 350 mg of dietary RNA (at 50 mg more per day). That is a full extra serving weekly. If you take two servings daily, that’s 700 mg additional dietary nucleic acids.

Dr. Frank tells us that a small amount dietary RNA goes a long way in terms of health benefits. He states that relatively small amounts of RNA (e.g., 100 mg daily) can provide noticeable health benefits.

Yet, larger amounts provide more benefits and create a stronger foundation for health (Frank 117). For example, individuals who benefit from larger amounts of RNA include athletes, individuals experiencing stress, and those seeking to recover from injuries.

An extra 350–700 mg dietary nucleic acids weekly can make a difference for health. It also means that a container Berries & Herbs can last longer than a container of Rejuvenate! PLUS in terms of providing more RNA per serving.

How much RNA do you need? That depends. 1,000 mg is a solid goal. That’s just two and one half (2.5) servings of Berries & Herbs or approximately five scoops.

HOW MUCH RNA DO WE NEED?

Dr. Benjamin S. Frank and other experts suggest an “optimal” intake in the range of 1,000–1,500 mg. This means 2.5 to 4 servings per day, or five to eight small scoops of Berries & Herbs. This amount can reasonably be attained by consuming, for example, a morning smoothie and an afternoon shake with three scoops of Berries & Herbs each.

After reaching a daily intake of about 1,500 mg, the benefits obtained by increased RNA consumption begin leveling. Greater intake of nucleic acids beyond this amount seems to provide fewer benefits.

An Olympic athlete in training might benefit from a daily RNA intake of 2,500 or 3,000 mg. Yet, most of us don’t have these high requirements because we aren’t pushing our bodies to such a level of activity and intensity.

That doesn’t mean you can’t gain similar benefits as those that might be conferred to an Olympian by optimizing your daily intake at a level that gives you sufficient dietary nucleic acids for rejuvenation, energy, and vitality.

Begin with a serving or two per day of Berries & Herbs (or another Rejuvenate! superfood), and work up to 1,000–1,500 mg daily.

GIVE IT TIME

It takes the body a few weeks to become saturated with nucleic acids. For me, it seems to be about 12 days.

Thus it can initially take two to four weeks after starting a high-RNA diet to see the benefits of nucleic acids. You may immediately notice greater energy or body warmth. (Likewise, when you stop taking nucleic acids, the benefits will still last several weeks.)

By consuming Berries & Herbs regularly after the body is saturated with RNA, you easily maintain your body’s supply of dietary nucleic acids. Maintaining your daily intake of dietary RNA helps sustain health.

INCLUDES HIGH-POTENCY MULTIVITAMIN WITH COENZYME B COMPLEX

A major benefit of Rejuvenate! Berries & Herbs is that it contains a high-potency multivitamin. Why is this important? While many people take a multivitamin, most multivitamins provide inadequate amounts of essential nutrients required for health.

In fact, many multivitamins provide the “Daily Value” established by the US government for critical nutrients. Daily values have replaced what was formerly known as “recommended daily allowances,” yet typically remain at or barely above levels required to prevent diseases of deficiency. These are not levels optimal for human health.

That is, daily values are not designed to create optimal health. They are minimum values based upon levels required for to avoid deficiencies. There is a huge difference between minimum levels needed for survival or prevent deficiencies. Indeed, the body assimilates and utilizes far higher levels to build and maintain robust health.

Still, the majority of multivitamins are formulated to provide minimum daily values. Thus, the majority of persons taking multivitamins obtain minimal values that do not create optimal health.

We at HPDI know the importance of a high-potency multivitamin for providing nutrients at levels that fall into ranges necessary for creating, supporting, and maintaining excellent health. After all, HPDI’s founder-formulator Dr. Hank Liers specializes in designing effective, high-potency multivitamins. He has done this for more than 25 years.

HPDI offer several excellent standalone multivitamins. But until the advent of Rejuvenate! Berries & Herbs, only HPDI’s Rejuvenate! PLUS superfood included a built-in multivitamin.

Dr. Liers wanted to confer the same nutritional advantages to consumers of Berries & Herbs. The vitamins added to HPDI’s superfoods like Berries & Herbs may not in every case completely replace the need for a standalone multivitamin. However, they do make the formula far more nutritious and more effective, partly helping the body better utilize dietary nucleic acids.

When it came to formulating Rejuvenate! Berries & Herbs, Dr. Liers not only incorporated a high-potency multivitamin, but also made sure the forms of these vitamins would be only the ones best used by the body.

Many of the vitamins (including the B complex vitamins) in Berries & Herbs are coenyzme-form vitamins or other forms best-recognized and/or utilized in the body. Best recognized almost always means natural. For example, Berries & Herbs does not include folic acid, which is a synthetic form of folate, but instead use calcium folinate (folinic acid), the natural co-enzyme form of folate.

Here are the vitamins in one serving that make up the multivitamin complex in Rejuvenate! Berries & Herbs:

• VITAMIN C (250 MG) (417% OF DAILY VALUE)

• VITAMIN E AS D-ALPHA TOCOPHERYL SUCCINATE (90 IU) AND HIGH GAMMA MIXED TOCOPHEROLS (25 MG) (300% OF DAILY VALUE)

• VITAMIN D3 (1,000 IU) (250% OF DAILY VALUE)

• VITAMIN K1 (0.5 MG) (625% OF DAILY VALUE)

• VITAMIN (100 MG)

• CHOLINE (50 MG)

• VITAMIN B1 FROM THIAMIN DIPHOSPHATE (7.5 MG) (500% OF DAILY VALUE)

• VITAMIN B2 FROM RIBOFLAVIN-5′-PHOSPHATE (6.8 MG) (400% OF DAILY VALUE)

• VITAMIN B3 AS NIACINAMIDE (60 MG) (300% OF DAILY VALUE)

• VITAMIN B5 AS PANTOTHENIC ACID (30 MG) (300% OF DAILY VALUE)

• VITAMIN B5 FROM COENZYME PANTETHINE (13 MG) (130% OF DAILY VALUE)

• VITAMIN B6 FROM PYRIDOXAL-5′-PHOSPHATE (10 MG) (500% OF DAILY VALUE)

• FOLATE AS FOLINIC ACID (1 MG) (250% OF DAILY VALUE)

• BIOTIN (0.9 MG) (300% OF DAILY VALUE)

• VITAMIN B12 AS METHYLCOBALAMIN (0.2 MG) (3,333% OF DAILY VALUE)

This list of course does not include other vitamins in Rejuvenate! Berries & Herbs ingredients, such as nutrients found in vegetable sprout powders, vegetable protein powders, stabilized rice bran, or in many of the herbal ingredients like burdock, ginger, or turmeric.

Another advantage of coenzyme vitamins is the body needs less of any given coenzyme vitamin because it does not need to convert non-coenzyme vitamins into usable forms. Therefore, the body requires less of a coenzyme-form vitamin.

That is a good thing because it does not cause the body to waste energy using enzymes to convert synthetic vitamins into their coenzyme forms. While coenzyme vitamins are relatively expensive to source, they are often very affordable to consumers because the body only needs tiny amounts of them.

Unlike many conventional B vitamins typically used in multivitamins, there are no losses of coenzyme B vitamins in vivo (in the body) due to conversion processes because they are immediately recognized by the body. This represents a powerful boost in effectiveness for minimal rise in cost.

HPDI uses coenzyme vitamins in many of their products because of their high value in terms of health and well being. The future of vitamin supplements lies in coenzyme-form vitamins because they are the most natural and most effective, and the most easily assimilated by the body.

In fact, HPDI was among the first companies to incorporate coenzyme form vitamins into its formulas. Dr. Hank Liers understands their value for human health. We will continue formulating products with coenzyme vitamins like Rejuvenate! Berries & Herbs.

VITAMINS INCREASE EFFECTIVENESS OF DIETARY NUCLEIC ACIDS

The vitamins (including coenzyme-form vitamins) in Rejuvenate! Berries & Herbs provide a significant benefit. They boost the effectiveness of the dietary nucleic acids.

Dr. Benjamin S. Frank certainly was clear about the effects of vitamins on the human body, including its capacity for using dietary RNA for therapeutic purposes. In his regimen for using nucleic acids for health as documented in Dr. Frank’s No-Aging Diet, he recommends taking a “therapeutic-strength” multivitamin daily (76).

Dr. Frank performed many human and animal studies using dietary nucleic acids. He nearly always included vitamins in his regimens. Very often he placed subjects on separate B-complex supplements.

Dr. Frank specifically states that the addition vitamin B-complex to the RNA regimen enhances the effects of dietary RNA. For example, he mentions how the B-complex support the rejuvenating effects of RNA on facial skin (Nucleic Acid Nutrition and Therapy 27).

Dr. Frank often specifies additional vitamins for dealing with certain conditions. For example, in his chapter on how his no-aging diet can help with osteoarthritis, he recommends patients take an additional 250 mg of pantothenic acid (vitamin B5) and 500 mg of vitamin C.

In his writings on dietary recommendations, Dr. Frank not only recommends B-complex vitamins, but also vitamin A, vitamin C, and vitamin D. He also incorporates a wide range of minerals in his formulas for patients.

Minerals he recommends include magnesium, zinc, and potassium. He also mentions other nutrients, such as coenzyme Q (ubiquinone/ubiquinol), enzymes, amino acids (e.g., carnosine, glutathione), and natural sugars (e.g., ribose and deoxyribose).

The inclusion of a complete multivitamin complex in Rejuvenate! Berries & Herbs helps make dietary nucleic acids more effective.

Learn more about our complete line of foundational supplements, including multivitamins.

HIGH-ORAC NUTRITION & ANTIOXIDANT PROTECTION

Rejuvenate! Berries & Herbs is an excellent, well-balanced superfood. Few superfoods stack up against it when you consider all the nutrition it provides.

Which brings us to another benefit: High antioxidant values. Berries & Herbs is in a class by itself when it comes to providing antioxidant power. That is, the power to quench free radicals.

One measure of the antioxidant values of foods and nutrients is ORAC value. ORAC stands for “oxygen radical absorbance capacity.” An ORAC test measures antioxidant capacities in vitro (test tube).

ORAC by itself is not the only or necessarily the best measure of antioxidant value because the oxygen radicals are not the only oxidants. A more comprehensive test would be the ORAC5.0 test, which measures the free-radical quenching powers of a sample against five different types of oxidants.

Nevertheless, ORAC remains a useful guide to the oxidant quenching powers of a superfood. Berries & Herbs provides an ORAC value of greater than 14,270 units per 38.9 gram serving.

There exist few individual foods, for example, that exhibit an ORAC value anywhere close to this figure. Even the highest-ORAC foods (like prunes or blueberries) fall short, being at most one-third as effective.

Most individual berries provide ORAC values in the range of 5,000–7,000 units per 100 gram serving (usually one cup or eight ounces), which translates into about 50–70 ORAC units per gram. Berries & Herbs tops such figures by providing 367 ORAC units per gram.

This means the ORAC value provided by Rejuvenate! Berries & Herbs in a single two-scoop serving (about 5 tablespoons) equals the ORAC the average high-ORAC berry (about 60 ORAC units/gram) provides in about six one-cup servings (48 tablespoons).

Serving-for-serving, Berries & Herbs is greater than six times more potent as an antioxidant substance than most foods considered high-ORAC. It also means you’ll need to consume far less Berries & Herbs to gain the antioxidant benefits you would from a much larger quantity of high-ORAC foods.

Berries & Herbs offers 367 ORAC units per gram! One serving is about 39 grams, so there is a huge amount of free-radical quenching power in just a single serving.

How huge is that? Since Berries & Herbs provides 14,276 ORAC units per serving (38.9 grams), then for a typical 100 gram ORAC equivalency, it provides an ORAC value of 36,684. Most ORAC food charts stop at about 14,500 units per 100 g (and average high-ORAC foods hover at 5,000 units per 100 g) to put those values in perspective.

Gram for gram, Berries & Herbs offers more than twice the ORAC value of the highest ORAC foods. And at least five to seven times more ORAC value than “average” high-ORAC foods (strawberries, raspberries, and blackberries) providing 5,000–7,000 ORAC units per 100 grams).

Antioxidant power is a unique benefit for Rejuvenate! Berries & Herbs, and one that is hard to be matched by any superfood, anywhere.

HIGH-ORAC BERRIES & POLYPHENOLS

I will talk more about about antioxidant nutrients in Rejuvenate! Berries & Herbs when discussing its cell-protecting herb and nutrient blend.

The major free-radical quenching power Berries & Herbs actually lies in its berry and polyphenol content. The extraordinary free radical-quenching capacities of Rejuvenate! Berries & Herbs relate directly to the fact that berries, as well as plant-based polyphenols (like those found in grapes and grape extract) contain relatively large quantities of antioxidants.

Also, the berries and polyphenols in in the formula come in highly concentrated forms. For example, we include potent berry blends like VitaBerry® Plus® and a carefully selected organic freeze-dried berry complex. The blends provide many types of berries, polyphenols, and other antioxidant nutrients acting synergistically to create higher ORAC values than a formula with fewer types of these berries or polyphenols.

NRF2 ACTIVATORS

Many plant-based antioxidants also act as Nrf2 activators. Nrf2 is a transcription factor encoded in human genes and whose antioxidant response pathway is our primary cellular defense against oxidative stresses. Nrf2 increases expression of important antioxidant enzymes in cells.

What this means is that Nrf2 activators are substances that activate the cells’ own production of antioxidant defenses. Because there is significant overlap between the food-based (i.e., exogenous) antioxidants and Nrf2 activators stimulating the body’s production of its own antioxidant enzymes, the berry complexes and polyphenols in Rejuvenate! Berries & Herbs serve double-duty as externally supplied antioxidants and stimulators of the body’s own antioxidant production.

The study of Nrf2 activator nutrients is an exciting area of research due to the potential for Nrf2 activators to significantly boost human health by enabling the body to unlock its potential for creating antioxidants.

The body already produces its own antioxidant defenses, but Nrf2 activators significantly enhance this process, thereby allowing far greater production of antioxidants for cell protection.

Rejuvenate! Berries & Herbs was not formulated as a Nrf2 activator formula. Yet, research shows there is significant overlap among the antioxidant substances in Berries & Herbs and nutrients known for activating Nrf2 transcription factor.

Known Nrf2 activators in Rejuvenate! Berries & Herbs include vegetable sprouts powder, blueberry powder, cranberry powder, strawberry powder, raspberry powder, vitaberry plus, burdock root, astragalus, turmeric, ginger root, rhodiola rosea (root), rutin, n-acetyl-l-cysteine, milk thistle extract, licorice (root), green tea extract, dandelion root, vitamin E (d-alpha tocopherol), lipoic acid, grape extract, and transresveratrol.

To learn more about Nrf2 activators, please see “The Amazing Healing Potential of Natural Nrf2 Activators,” “Natural Phytochemical Nrf2 Activators for Chemoprevention,” and other Nrf2-related articles on HPDI blog.

HPDI also offers Ultimate Protector, which is an antioxidant, vitamin C, and Nrf2 activator formula in a capsule. Ultimate Protector is not a high-RNA superfood, but a standalone HPDI foundational supplement. The two formulas can be combined, and in fact are formulated so they can be taken together in the HPDI system. Six small capsules of Ultimate Protector provide 486,000 ORAC5.0 units per serving. When taken together, the two formulas product more than 500,000 ORAC5.0 units per serving.

As noted, Berries & Herbs is not formulated as an antioxidant or Nrf2 activator formula per se. Yet, it provides significant antioxidant and Nrf2 activation.

When any Rejuvenate! superfood (including Berries & Herbs) is combined with Ultimate Protector (or another vitamin C and antioxidant formula), a multivitamin (like Multi Two), and essential fats (like Essential Fats Plus E), all four types of foundational formulas work together to support optimal health. Read more about how HPDI’s foundational supplements system works to support optimal health.

CELL-SUPPORTING HERBAL COMPLEX (“SUBFORMULA”)

One of the top features provided by Rejuvenate! Berries & Herbs is a blend of foods, herbs, and nutrients that collectively constitute a “subformula” created to support cell function and optimal cellular health.

Because this cell-protecting subformula contains many proven ingredients, it may appear to be more nutrient-dense substances heaped on top of an already densely packed Rejuvenate! Berries & Herbs superfood.

But the cell-protecting blend is something totally different. It’s not related to nucleic acid content, or to the built-in coenzyme B vitamin complex, or the high-quality protein content. It is a groundbreaking, game-changing set of ingredients that sets Berries & Herbs apart from nearly every superfood, including other Rejuvenate! superfoods.

The truth is that today our cells are under constant attack by thousands of different stresses. They are bombarded by toxic chemicals in the air, water, and soil. These chemicals include everything from pesticides and herbicides to household cleaning chemicals and industrial contaminants.

Our cells are also attacked by radiation. For example, elevated levels due to nuclear accidents like Fukushima and high background levels remaining from nuclear tests. Not to mention exposures from medical and dental x-rays. All these exposures lead to cumulative damage.

Other cellular toxins include daily exposures to chlorine, fluoride, bromine, and other halogens. And of course, exposures to heavy metals like lead, mercury, and cadmium from numerous other sources like dental amalgams, old paint, contaminated fish, and many other sources.

There are many other toxins our cells must deal with daily. Rejuvenate! Berries & Herbs is formulated to help cells deal with this assault by providing nutrients that support optimal function. This includes supporting your antioxidant defenses, immune system, energy production system, detoxification, and other important functions.

Dr. Hank Liers initially created this subformula of ingredients at the request of veterinarian Randy Aronson, VMD, who is Dr. Liers partner in the development of the 2Docs line of pet wellness formulas (www.IntegratedHealth.com/2docs-pet-supplements.html).

Dr. Randy was looking for a potent combination of ingredients that could optimally support the health and vigor, as well as recovery from illness of many of his pet patients suffering from degenerative diseases. Dr. Hank’s formula worked for Dr. Randy’s animal patients.

Dr. Hank saw its potential benefits for people. He began thinking about what a human version of the formula might look like, and how it could be incorporated into a product. At the time, HPDI was developing it’s latest Rejuvenate!™ superfood. While formulating the superfood, Dr. Hank realized that these “herbs” and other nutrients could perfectly complement the “berries” he put in the formula. “Berries & Herbs” was born.

Rejuvenate! Berries & Herbs thus contains a cell-protecting blend of organic and/or wildcrafted herbs and antioxidants. The cell-protecting subformula includes the following ingredients:

Organic astragalus, organic burdock root, organic turmeric root, organic ginger root, n-acetyl-l-cysteine (NAC), k-rutin™, standardized milk-thistle extract (>82% silymarin), standardized green tea extract (>95% polyphenols, >55% EGCG), organic licorice root, organic dandelion root, organic dulse, organic kelp, standardized Rhodiola rosea root (>3% rosavins), alpha-lipoic acid, BioVin™ grape seed, skin, and pulp extract, Immune-Assist™ (synergistic blend of organic mushroom extracts including Agaricus blazei, Cordyceps sinensis hybrid, Lentinula edodes, Grifola frondosa, Ganoderma lucidum, and Coriolus versicolor), transresveratrol (from Polygonum cuspidatum), germanium sesquioxide, and l-selenomethionine.

This subformula of ingredients makes a Berries & Herbs almost a “stealth” superfood. That is, many of the other benefits are more directly evident. Like high level of vegetarian-friendly protein or a built-in multivitamin.

The inclusion of dietary nucleic acids may be more obviously beneficial than cell-protective nutrients. But the subformula of cell-protective nutrients and herbs offers major benefits.

A nutritionist might read the label and realize the immune-building power of the cell-protective subformula. An acupuncturist might see its capacity for increasing energy or “chi.” A naturopath may identify potential for detoxification. In fact, most health professionals recognize value in the subformula’s ingredients.

The cell-supporting subformula is effective for supporting immunity, energy production, and detoxification, and other healthy benefits. The herbs and nutrients in the cell-supporting subformula make Rejuvenate! Berries & Herbs unique, and distinguishes it from other superfoods.

BERRIES & HERBS IS A HIGH-PROTEIN SUPERFOOD

Beyond the advantages of Rejuvenate! Berries & Herbs discussed, you might think the benefits stop there. But here is another one: Berries & Herbs is a high-protein powerhouse.

Dr. Hank Liers designed Berries & Herbs not only as a great-tasting, well-rounded superfood with dietary nucleic acids, multivitamins and minerals, but also as a high protein formula.

Higher protein (12 g per serving) means more complete nutritional support for people using Rejuvenate! Berries & Herbs as a food, snack, or nutritious drink.

The 12 grams of protein in a single two-scoop serving of Rejuvenate! Berries & Herbs is about six rounded tablespoons of it.

It’s easy to consume two scoops at a time because it tastes so good. Whether you choose to mix it in a smoothie, shake it up in jar, drink it plain in water, or add to fresh juice, you can count on its protein to help sustain you.

Adult females require about 46 grams of protein per day. Two servings of Rejuvenate! Berries & Herbs provides a woman with more than half (52%) of her daily recommended intake of protein.

Adult males require more protein (about 56 grams daily) than females. But even for men, two servings of Berries & Herbs provide almost 43% of their recommended daily protein intake.

PROTEIN SUITABLE FOR VEGETARIANS

The high-quality protein in Rejuvenate! Berries & Herbs comes from non-GMO brown rice, organic sprouted flaxseed (powder), organic hemp protein (powder), and a blend of garden sprouts. Here is the breakdown of the major protein sources in Rejuvenate! Berries & Herbs:

• High Protein Organic Garden Sprout Blend (3,000 mg/serving). Included in this blend are pea protein, quinoa sprouts, broccoli sprouts, alfalfa sprouts, daikon radish sprouts, red clover sprouts, and natural vanilla favor. Greater than 65% protein.

• Brown Rice Protein (Non-GMO) (9,000 mg/serving)

• Flaxseed Powder (3,000 mg/serving) (15–30% protein)

• Organic Hemp Protein Powder with Fiber (3,000 mg/serving)

I will present more information (below) regarding specific nutritional information for each of these superior vegetable-based protein sources. Selenium (from l-Selenomethionine), and Vitamin D3 (cholecalciferol).

FINAL WORDS: TASTE, TASTE & TASTE!!

I rarely save best things for last. But while delicious taste may not be a health benefit, it qualifies as one of the outstanding features of Rejuvenate! Berries & Herbs.

Berries & Herbs has a beautiful aroma and flavor that tickles taste buds with intense berry flavors and lingering fruity notes. Its taste is like a blast of berries in the mouth probably because that’s exactly what it is.

Most people like it. I myself was astonished that a superfood could taste so good.  If you haven’t tried it before, you’re likely to be pleasantly surprised.

Below I include detailed information about Rejuvenate! Berries & Herbs. Here is a superfood you can rely on for solid nutrition, great taste, and high levels of dietary nucleic acids supporting optimal health. ~

rejuvenate! berries & herbs high-RNA superfood

Rejuvenate! Berries & Herbs is a Dr. Hank Liers “original” formula.

DETAILED INFORMATION ABOUT REJUVENATE!™ BERRIES & HERBS

REJUVENATE!™ BERRIES & HERBS CONTAINS THE FOLLOWING UNIQUE INGREDIENTS

VitaBerry® Plus® (400 mg/serving)

VitaBerry® Plus® is a nutritious ingredient having extremely high ORAC value and is derived from freeze-dried Grape Seed, Wild Blueberry, Wild Bilberry, Cranberry, Tart Cherry, Prune, Raspberry Seed, Strawberry, Resveratrol, and Quercetin. In fact, this powder has an ORAC value in excess of 1.2 million units per 100 grams. Therefore at the 400 mg level that this material is found in Rejuvenate! Berries & Herbs it provides a minimum of 4,800 ORAC units. Because excessive exposure to free radicals may cause severe pain and inflammation, high-ORAC VitaBerry® Plus® significantly can contribute to preventing oxidative damage in the body.

VitaBerry® Plus® provides the following benefits:

• Superior source of natural antioxidants

• Helps prevent the effects of premature aging

• Promotes cardiovascular health

• Promotes healthy brain function and mental acuity

• Promotes healthy vision

• Promotes healthy blood sugar levels

• Excellent source of flavonoids and organic acids

• Promotes urinary tract health

• Promotes healthy skin

ORGANIC FREEZE-DRIED BERRY COMPLEX (6,000 mg)

The freeze-dried berry complex in Rejuvenate! Berries & Herbs is a proprietary blend of organic strawberries, raspberries, blueberries, and cranberries. Berries contain many powerful phytochemicals that can improve health. They are high in fiber and relatively low in sugar, and will not lead to surges to insulin when eaten in moderation.

BLUEBERRIES

The berries of the blueberry plant (Vaccinium angustfolium) exhibit among the highest levels of antioxidant activity of all fruits and vegetables. In particular, they contain the polyphenol anthocyanin (a pigment that gives fruits their red, purple and dark blue colors).

Anthocyanins are powerful flavonoid antioxidants that help protect the body from free radical damage and diseases associated with aging. Blueberries contain not only 25-30 different types of anthocyanins, but also chlorogenic acid (believed to be a tumor inhibitor), and the pigment cyanidin (an anti-inflammatory).

Blueberries contain silicon (an element believed to be helpful for the pancreas) and are considered to be helpful for diabetes.

Blueberries also have been effective for many health conditions, and may protect the body against age related declines in neural and cognitive functions, short-term memory loss, macular degeneration of the retina, and urinary tract infections (due to compounds that inhibit the adherence of bacteria to uroepithelial walls).

There is evidence that blueberries may improve glucose metabolism via the action of chlorogenic acid, serve as a powerful anti-inflammatory agents (useful against arthritis and other inflammatory conditions), and reduce the risk of tumorigenesis.

The antioxidant power of foods is measured in ORAC units (Oxygen Radical Absorbance Capacity), which indicate the total amount of a food’s antioxidant capacity. High ORAC values indicate greater antioxidant capacity. High-ORAC foods may therefore protect cells from oxidative damage.

Two studies have shown that eating high-ORAC fruits and vegetables (or doubling the intake of fruits and vegetables) elevates the antioxidant capacity of the blood 13-25% (see Jrnl of Clinical Nutrition 68: 1081-87).

When ORAC values for 40 fruits and vegetables were measured by the USDA’s Agricultural Research Service at its Human Nutrition Research Center on Aging (HNRCA) at Tufts University, fresh blueberries scored the near the top, having 2,400 ORAC units per 100 grams (3.5 ounces).

Serum levels of anthocyanins found in blueberries have been shown to rise significantly after ingestion of freeze-dried blueberry powder and correlate with an increase in serum antioxidant capacity as measured in ORAC units (Mazza et al., Jrnl of Agricultural and Food Chemistry 50 (26): 7731-37; 2002)

CRANBERRIES

Cranberries (Vaccinium macrocarpon) are native to the boggy regions of temperate and subalpine North America and Europe. Although Native Americans used them extensively, they were first cultivated in the U.S. in the early 19th century. Cranberries grow on viney plants belonging to the heath family Ericaceae that also includes blueberries, bilberries, huckleberries, and bearberries (Arctostaphylos uva ursi).

Cranberries contain tannins, fiber, anthocyanins (and other flavonoids), and Vitamin C. Their tannins prevent bacteria from attaching to cells. Consequently, cranberries have been used against infections, including urinary tract infections. In addition, cranberries may be helpful in protecting against heart disease and stroke.

Cranberries are an especially good source of antioxidant polyphenols. In animal studies, the polyphenols in cranberries have been found to decrease levels of total cholesterol and so-called “bad” cholesterol. Cranberries may also inhibit the growth of tumors in human breast tissue and lower the risk of both stomach ulcers and gum disease.

RASPBERRIES

Raspberries (and blackberries) belong to the rose family (Rosaceae). The red raspberry was first cultivated in Europe about 400 years ago. There are several varieties native to North America, including a black raspberry native to southern states (that has been crossed with European varieties) and a red raspberry (Rubus idaeus) from which originate most commercially grown varieties.

Raspberries contain anthocyanins, fiber (including the cholesterol lowering soluble form pectin), phytochemicals (ellagic acid, coumaric acid, ferulic acid), calcium, and vitamins A, C, and E. Ellagic acid is known to be antiviral, antibacterial, anticarcinogenic, and antimutagenic. It has been shown to inhibit the mutation of cells and to prevent the binding of carcinogens to DNA.

Raspberries have 1,220 ORAC units per 100 grams (3.5 ounces), among the highest of the forty fruits and vegetables tested by the USDA.

STRAWBERRIES

Strawberries long have grown wild in the world’s temperate regions. They have been cultivated for several thousand years and were prized among the ancient Romans. Most of the common varieties of strawberry derive from a hybrid (Frangaria x ananassa).

Strawberries have an ORAC value of 1,540, which is very high among the fruits and vegetables tested by the USDA. They are a good source of vitamins C, K, B2, B5, B6, and folate. They also contain appreciable amounts of the minerals manganese, iodine, and potassium, as well as dietary fiber. Like other berries, the antioxidants contained in strawberries may be useful against diseases of the heart and arteries by preventing the oxidation of lipids.

The phytonutrient phenols most abundant in strawberries are anthocyanins and ellagitannins. The anthocyanins help to prevent oxidative damage from free radicals in body. The unique phenol profile of the strawberry enables it not only to protect the heart, but also to fight inflammation.

Studies have shown strawberries protect the brain from oxidative stress and may therefore reduce age-related cognitive decline in brain function.

CELL PROTECTIVE ORGANIC & WILDCRAFTED HERBS AND ANTIOXIDANTS

ORGANIC ASTRAGALUS POWDER (200 mg)

Astragalus is derived from the root of a plant (Astragalus membranaceus) in the pea family. It is an adaptogen, meaning it has a balancing effect on bodily functions. Astragalus is often used to strengthen or tone the body’s overall vitality, improve digestion, and support the spleen. Studies confirm it contains biologically active compounds, including a polysaccharide that stimulates the immune system.

ORGANIC BURDOCK ROOT (200 mg per serving)

Burdock root is one of the foremost cleansing herbs, providing nourishing support for the blood, the liver, and the natural defense system. It is rich in Vitamins B1, B6, B12, and E, as well as manganese, copper, iron, zinc, sulfur, and more. Burdock root is often found in tonic formulas and special blends designed for internal cleansing.

In traditional herbal texts, Burdock root is described as a “blood purifier” or “alterative” and was believed to clear the bloodstream of toxins. During the industrial revolution, Burdock was used as a medicine to help people cope with the increasing environmental pollution.

Burdock root has been used both internally and externally for eczema and psoriasis, as well as to treat painful joints and as a diuretic. In traditional Chinese medicine, burdock root, in combination with other herbs, is used to treat sore throats, tonsillitis, colds, and even measles. It is eaten as a vegetable in Japan and elsewhere. Burdock is a mild laxative. It also aids in the elimination of uric acid. The herb contains polyacetylenes that have both anti-bacterial and anti-fungal properties.

ORGANIC TURMERIC ROOT POWDER (150 mg per serving)

Turmeric, a polyphenol, contains substances called curcuminoids that are powerful antioxidants, pain relievers, and anti-inflammatories. Curcuminoids have been shown to exhibit antibacterial activity.

ORGANIC GINGER ROOT (150 mg per serving)

Ginger rhizome (Zingiber officinale) is an incredibly active and effective gastrointestinal aid with the following properties: 1) Contains a digestive enzyme whose effectiveness even exceeds that of papain; 2) Stimulates the flow of saliva and increases the concentration of the digestive enzyme amylase in the saliva; and 3) Activates peristalsis and increases intestinal muscle tone. Ginger is also known to be helpful in cases of nausea.

N-ACETYL-L-CYSTEINE (NAC) (100 mg per serving)

NAC is a powerful free radical scavenger. A majority of orally ingested NAC rapidly undergoes deacetylation to form L-cysteine, which is necessary for glutathione production. NAC, therefore, has powerful implications for immune function and increasing the body’s free-radical trapping capacity.

NAC’s effectiveness in treating patients with acetaminophen overdose is well documented. NAC has been used with good results in treatment of respiratory illness and diseases such as chronic bronchitis and chronic obstructive pulmonary disease. Additionally, NAC has well-known antimucolytic properties, and has been shown to increase mucociliary transport in lungs.

k-RUTIN™ (100 mg per serving)

Rutin (quercetin-3-rutinoside) is a glycoside of the flavonoid quercetin. The chemical structure of rutin and quercetin consequently are very similar. Indeed, both rutin and quercetin are used in many countries as medications for blood vessel protection, and both are found as ingredients in numerous nutritional supplement preparations and herbal remedies.

k-Rutin™ is an alkalinized form of rutin having greater solubility than the rutin included in traditional nutritional supplements. That is, based on laboratory studies, it is a more soluble anthocyanin moiety (functional group) than rutin.

RECOGNIZED HEALTH BENEFITS OF RUTIN

• Rutin inhibits platelet aggregation and decreases capillary permeability, which thins blood and improves circulation

• Rutin exerts anti-inflammatory activity

• Rutin inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body. It helps change glucose into a sugar alcohol called sorbitol that is associated with cataract formation

• Rutin strengthens capillaries. It therefore can reduce symptoms of capillary- and circulatory-related health conditions, including hemophilia. It also may help prevent common venous edemas of legs and feet.

• Rutin can reduce cytotoxicity of oxidized LDL cholesterol and reduce the risk of heart disease

• Evidence indicates rutin can be used to treat hemorrhoids, varicosis, and microangiopathy

• Rutin acts as an antioxidant. A study of the superoxide anion scavenging activity of rutin and six other flavonoids (including quercetin, morin, acacetin, hispidulin, hesperidin, and naringin) showed rutin had the strongest scavenging activity.

• Rutin provides essential support molecules for Vitamin C absorption and helps prevent breakdown of Vitamin C in the body before it is metabolized

• Rutin is believed to stabilize the collagen matrix by preventing free-radical damage, thereby helping to maintain the health of the body’s collagen

Rutin is a flavonoid (or bioflavonoid) within a class of flavonoids that includes hesperidin, quercetin, eriodictyl, and citron. Rutin is essential for the absorption of Vitamin C.

While rutin in nature is found in many nutritious foods (e.g., citrus, red apples, teas, broccoli, onions), it is easily taken in supplement form. This is especially important because the body cannot produce flavonoids. They must be supplied through diet (and it is prudent to take them in supplemental form in order to maximize health).

Flavonoids boost the effectiveness of Vitamin C, improve eye health, strengthen capillaries, reduce cholesterol, improve blood circulation, and act as antioxidants. Recent studies indicate flavonoids may be a significant factor in guarding the body against infections and major illnesses.

MILK THISTLE EXTRACT (STANDARDIZED TO GREATER THAN 82% SILYMARIN) (100 mg per serving)

Extensive research has shown that silymarin – the major component of milk thistle extract – exerts both a protective and restorative effect on the liver and is able to stimulate the growth of new liver cells to replace old damaged cells.

GREEN TEA EXTRACT (STANDARDIZED TO GREATER THAN 95% POLYPHENOLS & GREATER THAN 55% EGCG) (100 mg per serving)

Green tea extract is used primarily for its free radical fighting capabilities. Its key ingredient, epigallocatechin gallate (EGCG), protects against digestive and respiratory infections. It helps block the tumor-promoting actions of carcinogens, ultraviolet light, and metastasis from an original site in the skin, stomach, small intestine, liver or lung. EGCG also reduces platelet aggregation about as much as aspirin.

Green tea is very effective in inhibiting pathogenic bacteria that cause food poisoning and increases levels of friendly intestinal bacteria. It also blocks the attachment of the bacteria associated with dental caries to the teeth.

ORGANIC LICORICE ROOT (100 mg per serving)

Licorice is a moist, soothing herb that is anti-inflammatory and expectorant, controls coughing and has hormonal and laxative effects. It is further used to prevent liver toxicity and to treat tuberculosis and adreno-corticoid insufficiency.

Licorice contains flavonoids, isoflavonoids, chalcones, and triterpene saponins, with the main being glycyrrhetinic acid with 24-hydroxyglycyrrhetinic acid (which is 100 times sweeter than sugar).

Licorice is used internally for asthma, bronchitis, coughs, peptic ulcer, arthritis, allergic complaints and after steroid therapy. It is said to accelerate the healing of peptic ulcers and is used in cases of adreno-corticoid insufficiency. It is also used in Chinese medicine to revitalize the heart and treat palpitations, boosting the spleen, for coughing and wheezing, as well as detoxifying the body and digestive system.

ORGANIC DANDELION ROOT POWDER (100 mg per serving)

Dandelion root enhances the flow of bile, improving such conditions as liver congestion, bile duct inflammation, hepatitis, gallstones, and jaundice.

ORGANIC NOVA SCOTIA DULSE (100 mg per serving)

The dulse in Rejuvenate! Berries & Herbs is hand-harvested, low-temperature sun-dried, and immediately milled into a fine powder. The entire harvesting and handling process follows strict organic standards to eliminate possible processing contamination. Analytical testing shows that our dulse contains approximately 30% minerals including over 30 minerals (includes many trace minerals).

ORGANIC ICELANDIC KELP (100 mg per serving)

The milled kelp (Laminaria digitata) in Rejuvenate! Berries & Herbs grows deep in the cold subtidal waters of northwestern Iceland. This kelp is the only commercially available kelp that is sustainably harvested, dried, milled and bagged following the organic standards of Quality Assurance International. It is also an excellent source of organic iodine.

RHODIOLA ROSEA ROOT (STANDARDIZED TO GREATER THAN 3% ROSAVINS) (100 mg per serving)

Rhodiola rosea (aka “Arctic root”) is categorized as an adaptogen due to its observed ability to increase resistance to a variety of chemical, biological, and physical stressors. It has a reputation for stimulating the nervous system, improving depression, enhancing work performance, improving sleep, eliminating fatigue, and preventing high altitude sickness.

Rhodiola species contain a range of antioxidant compounds, including p-tyrosol, organic acids (gallic acid, caffeic acid, and chlorogenic acid), and flavonoids (catechins and proanthocyanidins).

The adaptogenic properties, cardiopulmonary protective effects, and central nervous system activities of Rhodiola rosea have been attributed primarily to its ability to influence levels and activity of biogenic monoamines such as serotonin, dopamine, and norepinephrine in the cerebral cortex, brain stem, and hypothalamus.

ALPHA-LIPOIC ACID (75 mg per serving)

Alpha lipoic acid is normally made in the human body, where it functions primarily as an important metabolic nutrient. As such, it plays a crucial role in the metabolism of both fats and carbohydrates into energy. In addition, lipoic acid functions as an extremely powerful antioxidant capable of trapping many different types of free radicals in the body.

Because it is both water and fat soluble, lipoic acid can operate in a broader range of body tissues than most other antioxidants. Its small size allows lipoic acid to enter areas of the body not easily accessible to many other substances; this allows lipoic acid, for example, to enter the cell nucleus and prevent free-radical damage to DNA.

Because it is such a powerful antioxidant and can easily function and exist in both a reduced and oxidized state, lipoic acid can protect other important antioxidants such as glutathione, Vitamin E, and Vitamin C. Lipoic acid is also able to chelate heavy metals such as lead, cadmium, mercury, free iron, and free copper out of the body.

BIOVIN™ HIGH OPC GRAPE EXTRACT (PULP, SKIN, AND SEED) (50 mg per serving)

The BioVin™ grape extract in Rejuvenate! Berries & Herbs is extracted by ethanol and water and contains the highest percentage of OPCs of any product on the market. OPCs, a class of bioflavonoids, are one of nature’s most powerful free-radical scavengers.

As bioflavonoids, OPCs help to increase the effectiveness of Vitamin C. OPCs cross the blood-brain barrier to provide antioxidant protection to central nervous system tissue.

Studies have clearly demonstrated that OPCs improve and normalize capillary activity, strengthening capillary walls. OPCs bind to collagen fibers, realigning them in the process to a more youthful, undamaged structure. Elasticity, flexibility, and strength are thereby restored to connective tissue.

IMMUNE-ASSIST™ (40 mg per serving)

A combination of more than 200 different polysaccharides, derived from the enzymatic breakdown of complex organic plant material from six different species of medicinal mushrooms.

These mushrooms include Agaricus blazei, Cordyceps sinensis hybrid, Lentinula edodes, Grifola frondosa, Ganoderma lucidum, andCoriolus versicolor. Immune-Assist™ is made in the US using only USDA Certified Organic materials.

Immune-Assist is similar to other mushroom based polysaccharides in that it is formulated through an enzymatically activated process whereby complex cross-linked polysaccharides from vegetable sources are converted to biologically active immunomodulators composed of simpler sugars such as arabinose and xylose.

Immune-Assist™ does contain simple polysaccharides, but it also contains much more complex polysaccharides, including cross-linked beta mannans and beta-glucans, and hetero-polysaccharides which combine both alpha- and beta-bound monosaccharides in the same molecule. These complex polysaccharide compounds are not found in earlier-generation bran-based supplements like AHCC. This is the reason that Immune-Assist™shows such a greater range of immuno-modulation bioactivity than any other bran-based supplements.

Immune-Assist™ not only contains arabinoxylane, but also lentinan, grifolan (Dr. Nanba’s original Maitake D-Fraction), PSK and PSP, and active hemicellulose correlated compound (AHCC).

TRANS-RESVERATROL (FROM POLYGONUM CUSPIDATUM) (10 mg per serving)

Trans-resveratrol provides anti-oxidant protection, boosts cellular energy, and balances the immune system. It has been proven in studies to activate the SIRT1 longevity gene and enhance cellular productivity. Several research studies have shown that trans-resveratrol significantly modulates biomarkers of bone metabolism, inhibits pro-inflammatory enzymes such as COX-1 and COX-2, and exhibits chemopreventive agents, anticarcinogenic properties, cardioprotective effects, neuroprotective properties, and caloric restrictive behavior. Trans-resveratrol has shown the ability to increase the number of mitochondria thereby increasing total daily energy.

Studies have shown that trans-resveratrol promotes an increase in mitochondrial function, that translates into an increase in energy availability, improved aerobic capacity, and enhanced sensorimotor function.

GERMANIUM SESQUIOXIDE (15 mg per serving)

Germanium sesquioxide shows considerable promise in immune support by boosting levels of gamma interferon in a dose dependant fashion. Studies indicate that germanium sesquioxide may be effective in combating certain viral and malignant conditions. Other studies suggest benefits toward free radical damage, cataracts, hypertension, and osteoporosis.

SELENIUM (from L-SELENOMETHIONINE) (25 mcg per serving)

Selenium is a trace mineral required in the body. Its primary function is carried out in the form of selenomethionine, which is incorporated into four active sites of the enzyme glutathione peroxidase. This enzyme protects the body against free-radical damage (especially when it occurs in cell membranes) caused by the oxidation of unsaturated fatty acids.

Selenium historically has been linked to Vitamin E because Vitamin E blocks the production of oxidized fatty acids in cell membranes. Selenium also appears to exert antioxidant activity by itself. Selenium is involved in the production and utilization of thyroid hormone, and it is antagonistic to heavy metals, including lead, mercury, aluminum, and cadmium.

According to a publication of the National Research Council (NRC), “One could reasonably suppose that selenium is involved [e.g., exerts a protective function] in such human medical problems as cataracts, diseases of the liver, cardiovascular or muscular diseases, and the aging process.” Selenium in its vital role in glutathione peroxidase affects all components of the immune system, including the development and function of all white blood cells.

HIGH PROTEIN GARDEN SPROUT BLEND (3,000 MG PER SERVING)

For thousands of years individuals have been using the healing power of vegetable sprouts. When a dormant seed begins to sprout, it enters a stage of tremendous vitality. Antioxidants and enzymes are produced that protect the developing plant and enable rapid growth.

Exciting new research has identified the role of glucosinolates and iosthiocyanates (classes of phytochemicals inherent in sprouts) that appear to positively influence metabolism in the human body.

Studies have suggested that sprout phytonutrients can promote the maintenance of healthy organs, healthy anti-inflammatory conditions, reduce the effects of toxins, and help to fight the effects of age-related free-radical activity.

The specific blend of sprouts used in Rejuvenate! Berries & Herbs was chosen to provide all of the above benefits while also yielding a blend with greater than 65% protein. Included in this blend are pea protein, quinoa sprouts, broccoli sprouts, alfalfa sprouts, daikon radish sprouts, red clover sprouts, and natural vanilla favor.

BROWN RICE PROTEIN (NON-GMO) (9,000 MG PER SERVING)

The rice protein in Rejuvenate! Berries & Herbs is extracted using a proprietary enzyme process starting from non-genetically modified rice. Our rice protein is processed without the use of acids, bases or other chemicals. In addition, the protein content of the extracted product is over 70%. That is substantially higher than other extraction methods (less than 53%) that leave a much higher percentage of carbohydrate in the end product. The protein of brown rice contains all of the essential amino acids, but it is somewhat low in the amino acid lysine. For this reason we have added supplemental lysine (400 mg/serving) to the formula.

FLAXSEED POWDER (3,000 MG PER SERVING)

Flax seeds (Linum usitatissimum L.) contain essential fatty acids (an excellent vegetarian source of omega-3 alpha-linolenic acid), protein, soluble fiber, insoluble fiber, antioxidant lignans, minerals, and vitamins. Lignans are a phytoestrogens considered to be antioxidants. Flax seeds contain among the highest levels of lignans among all plant foods.

Whole flax seeds are an excellent nutritional food. However, whole flax seeds can be difficult to digest and its nutrients typically are poorly absorbed. Flax seeds contain natural enzyme inhibitors that prevent digestion. This natural protective mechanism means that a seed may be eaten, pass through the body, and still grow into a plant (i.e., completely surviving the digestive process!).

Milling or grinding the seeds does not decrease natural enzyme inhibitors that reduce the bioavailability of flax. Only sprouting decreases natural inhibitors that otherwise will prevent complete digestion, absorption, and assimilation of flax seeds.

Flaxseed Powder provides an ideal solution to maximize health benefits of flax seeds. The process of germination fundamentally changes nutrient composition of the seed.

Nutrients including enzymes, amino acids, and vitamins substantially increase and become more bioavailable. This allows for better availability and absorption of these nutrients in the body. For example, sprouting flaxseed doubles antioxidant (ORAC) value. In addition, “anti-nutrients” such as phytic acid, enzyme inhibitors, and insoluble fibers all decrease. This further increases bioavailability and nutrient absorption of flax, and thereby boosting the health benefits attainable from consuming it.

The flaxseed powder in Rejuvenate! Berries & Herbs contain oil amounts varying between 38–45%, with the oil offering a high percentage (47–53%) of the omega-3 alpha-linolenic acid (ALA) and 15–18% omega-6 linoleic acid.

Alpha-linolenic acid (ALA) is an essential fatty acid acting in the human body as a substratum for the transformation into EPA and DHA through the action of desaturation and elongation enzymes. The seeds also contain some omega-6 essential fatty acids and exhibit a favorable omega-3 to omega-6 ratio of 3:1. Modern diets contain too few omega-3 fatty acids.

Flaxseed powder possess 15–30% protein (typically 20%) and the amino acids of flax protein have no limiting factors in the adult diet (i.e., they are a complete protein source having all of the essential amino acids in an appropriate balance). Flax seeds are also a source of magnesium, calcium, potassium, phosphorus, zinc, and copper. They also have demonstrated antioxidant activity. The most important antioxidants they provide are phytoestrogens known as lignans.

The human body easily digests flax seeds. The seed’s outer layer is rich in mucilloid soluble fiber (flax seed possesses 10–15% soluble fiber) and absorbs at least four times its weight in water. When mixed with water or stomach juices, the seeds form a gel that creates a physical barrier between the carbohydrates and the digestive enzymes that break them down. The carbohydrates thereby are digested and converted into glucose (blood sugar) at a slow, uniform rate. There is no insulin surge or spike needed to lower the blood sugar level. The water-retaining capacity of the gel also maintains bodily hydration (i.e., helping level out water intake) and electrolyte balance.

ORGANIC HEMP PROTEIN POWDER WITH FIBER (3,000 MG PER SERVING)

We have chosen to include certified organic hemp protein with fiber in Rejuvenate! Berries & Herbs. This raw whole food protein powder is rich in complete protein, branch chain amino acids, omega 3 and 6 essential fatty acids and healthy dietary fiber. Our certified organic hemp protein powder is cold milled from certified organic hemp seed and contains contains 37% protein, 43% fiber and 10% fat. The product contains no genetically modified organisms, no additives or preservatives, no THC, and is kosher certified.

A MULTIVITAMIN WITH COENZYME B-COMPLEX

We have added the following vitamins to the formula: Vitamin C (250 mg), Vitamin E as d-alpha tocopheryl succinate (90 IU) and high gamma mixed tocopherols (25 mg), Vitamin D3 (1,000 IU), Vitamin K1 (0.5 mg), inositol (100 mg), choline (50 mg), calcium pantothenate (30 mg), niacinamide (60 mg), pantethine (13 mg), pyridoxal-5′-phosphate (10 mg), thiamin diphosphate (7.5 mg), riboflavin-5′-phosphate (6.8 mg), calcium folinate (1 mg), biotin (0.9 mg), and methylcobalamin (0.2 mg).

While coenzyme vitamins usually cost significantly more than the synthesized vitamins (up to 50 times more), they remain quite affordable because they are only required by the body in very small amounts. That is, the body only needs small amounts because there are no in vivo losses related to any conversion processes. We therefore include coenzyme form vitamins in Rejuvenate! Berries & Herbs in quantities helpful to the body.

The inclusion of coenyzme forms of vitamins significantly contributes to making our supplement formulas more effective than if we used conventional (i.e., non-coenzyme form) vitamins. Moreover, it increases effectiveness without substantially raising our costs. Thus, the benefits considerably outweigh the costs, especially for individuals who consume our formulas, thereby reaping the benefits coenzyme vitamins offer for human health and well being.

ENZYMES TO ENHANCE NUTRIENT UTILIZATION

The complexity and significant amounts of proteins and peptides found in Rejuvenate! Berries & Herbs requires the combination of multiple proteases to optimize digestion. Proteins are made up of over twenty different amino acids, with each combination presenting different characteristics. Each of the proteolytic enzymes in Rejuvenate! Berries & Herbs offers different abilities to break the chemical bonds found in the proteins. However, the combination of enyzmes shows the greatest rate of hydrolysis.

Peptidase breaks amino acids off the ends of the peptide chain. Our proprietary enzyme complex contains both amino-peptidase and carboxy-peptidase activities, and therefore it can remove amino acids from both ends of the peptide chain. Protease 4.5 breaks bonds at points within the peptide chain dependent upon their bond specificities. Significant action of this enzyme has been seen both in the laboratory and in digestive product usage. Protease 4.5 has an optimal pH of 4.5 (pH range 2.0 to 6.0). Protease 6.0 has an optimal pH of 6.0 (pH range 4.0 to 11.0). Together these proteases provide proteolytic action throughout the human digestive system.

Because Rejuvenate! Berries & Herbs contains a large amount of plant-based ingredients, we have added the enzyme cellulase to the formula. Cellulase offers distinct advantages for individuals consuming large amounts of vegetable matter. This enzyme hydrolyzes the bonds in various fibers. Cellulase hydrolyzes glucose-glucose bonds in cellulose. By disrupting the structure of the fiber matrices that envelop most of the nutrients in plants, cellulase increases the nutritional value of fruits and vegetables.

PREBIOTICS AND TASTE ENHANCERS

Rejuvenate! Berries & Herbs includes inulin (from chicory root), xylitol (from organic hardwoods), mannitol (a powerful superoxide free-radical trapper), malic acid (a Krebs cycle intermediate), organic mixed berry flavoring, organic vanilla flavoring, and stevia leaf extract. We include these ingredients in order to provide prebiotics, enhanced taste, and various health benefits.

ORGANIC ALOE VERA EXTRACT

We demand high-quality source materials containing the most biologically active and effective ingredients available. The aloe vera selected for Rejuvenate! Berries & Herbs meets our high standards. This aloe vera extract combines ground breaking research and state-of-the-art manufacturing to preserve and enhance aloe vera’s natural benefits in the form of ACTIValoe™, a standardized certified organic Aloe vera with 10% total polysaccharides by weight.

The purity and quality of ACTIValoe™ is verified by scientific analysis (i.e., Proton NMR Analysis, HPLC, SEC, etc.) and is certified by the International Aloe Science Council for its content and purity. Furthermore, ACTIValoe™ is guaranteed to retain biological activity to help deliver the healing properties of Aloe vera.

Biologically active aloe is believed to reduce severe joint and muscle pain associated with arthritis, as well as pain related to tendinitis and injuries. When applied directly to the area of pain, aloe vera penetrates the skin to soothe the pain. Studies have also found that ingestion of biologically active aloe on a daily basis can help prevent and cause a regression of adjutant arthritis.

Aloe vera extract can relieve gastrointestinal problems and may be one of the plant’s most ancient uses. Even today, people consume aloe vera to help relieve ulcerous, gastrointestinal and kidney problems. People have described improved regularity, greater intestinal comfort and enhanced energy levels after ingesting biologically active aloe vera. In addition, many who have suffered from indigestion, irritable bowel syndrome, increased stomach acid, peptic and duodenal ulcers, and colitis report relief from these conditions following ingestion of aloe vera.

Coronary heart disease is one of the major causes of death in the US. However, studies suggest that the ingestion of aloe vera may have a beneficial effect on the accumulation of blood fat lipids associated with the disease.

Test groups given aloe vera showed a decrease in total cholesterol, triglyceride, phospholipid, and nonesterified fatty acid levels, each of which, when elevated, seem to accelerate the accumulation of fatty material in large and medium-sized arteries, including the coronary arteries of the heart.

REJUVENATE!™ BERRIES & HERBS CONTAINS THESE INGREDIENTS FOUND IN HPDI’S REJUVENATE! (ORIGINAL) FORMULA

CHLORELLA GROWTH FACTOR (CGF) (200 MG PER SERVING)

In the early 1950s, the Japanese researcher Fujimaki separated a previously undiscovered substance from a hot-water extract of chlorella that is now known as “Chlorella Growth Factor” (CGF). CGF is a nucleotide-peptide complex comprised mostly of nucleic acid derivatives.

The sugars identified in the nucleotide include glucose, mannose, rhamnose, arabinose, galactose, and xylose. Amino acids found in the peptide include glutamine, alanine, serine, glycine, proline, asparagine, threonine, lysine, cysteine, tyrosine, and leucine.

It is known that CGF is produced during intense photosynthesis and enables chlorella to grow extremely rapidly. During this process, a single cell may multiply into four daughter cells as rapidly as every 20 hours. CGF not only promotes this rate of reproduction, but also is itself rapidly increased.

In Japan, Dr. Yoshiro Takechi showed that CGF stimulates lactobaccilus (the “good” bacteria) to grow at four times the usual rate. Experiments with microorganisms, young animals, and children have demonstrated that CGF promotes faster than normal growth. In adults and mature organisms, CGF appears to enhance the functions of nucleic acids at the cellular level that relate to the production of proteins, enzymes, and energy, as well as to stimulate tissue repair and offer protection against toxic substances at the cellular level.

D-RIBOSE (2,000 MG PER SERVING)

D-Ribose (ribose) is a sweet, crystalline, water-soluble powder. It is a naturally occurring 5-carbon sugar found in all living cells. Ribose is a component of RNA and therefore essential for living creatures. It is also a component of ATP, NADH, and other metabolism-related substances.

The biological importance of ribose relates to the fact that it is the rate-limiting compound that regulates the activity of the purine nucleotide pathway of adenine nucleotide metabolism. As such, ribose plays a central role in the synthesis of ATP, coenzyme-A, flavin adenine dinucleotide (FAD), nicotinamide adenine dinucleotide (NAD), DNA, RNA, and other important cellular constituents.

Ribose is the only known compound the body can use for performing this critical metabolic function. Specifically, ribose administration bypasses the slow and rate-limited pentose phosphate pathway to stimulate adenine nucleotide synthesis and salvage in vivo. In addition, it has been shown that de novo adenine nucleotide synthesis in skeletal muscle is rate limited by the availability of ribose.

D-ribose is commonly found in foods, especially foods high in RNA (ribonucleic acid), such as brewer’s yeast. D-ribose is essential for life and can be made by the body (e.g., from glucose). However, d-ribose from food sources can significantly boost the amount of ribose available to the body, thereby enhancing processes that utilize it.

Ribose derivatives play a significant role in the body. Important ribose derivatives encompass those having phosphate groups attached at the 5 position, including mono-, di-, and triphosphate forms, and 3-5 cyclic monophosphates. Diphosphate dimers, known as coenzymes, form an essential class of compounds with ribose. When such purine and pyrimidine derivatives are coupled with ribose, they are known as nucleosides(bases attached to ribose). Phosphorylated nucleosides are known as nucleotides. When adenine (a purine derivative) is coupled to ribose it is known as adenosine. ATP is the 5′-triphosphate derivative of adenosine. (The adenine portion of ATP consists of ribose and adenine. The triphosphate portion of ATP consists of three phosphate molecules.)

Ribose therefore is found in many important biological molecules, including adenosine triphosphate (ATP), nucleotides and nucleotide enzymes, and in RNA. D-ribose (as ribonucleoside diphosphates) notably converts to deoxyribonucleoside diphosphates, precursor molecules for DNA.

Ribose generates adenosine triphosphate (ATP) in the body. Supplemental ribose increases the rate at which ATP is generated, thereby improving exercise performance and enabling faster muscle growth. This is possible because supplemental ribose enables the body to bypass the conversion steps needed to create or re-create the adenosine nucleotide. Replacing adenine nucleotides normally takes time for the body to accomplish, and this process can reduce the rate of healing and repair (e.g., of muscle fibers). Supplemental ribose essentially increases the speed at which adenosine nucleotides can be replaced by providing raw material for the creation of more ATP.

Ribose similarly has been shown to boost synthesis and salvage of other nucleotides in the body, including those found in heart and skeletal muscle. Supplemental ribose again bypasses the rate-limiting conversion processes (i.e., of the pentose phosphate pathway), thereby speeding syntheses of nucleotides that provide energy to these tissues.

RIBOSE AS A SIGNIFICANT COMPONENT OF NUCLEIC ACIDS

Nucleotides are the molecular building blocks of DNA and RNA. They are chemical compounds consisting of a heterocyclic base, a 5-carbon sugar (ribose or deoxyribose) and at least one phosphate group. They are the monomers of nucleic acids, and 3 or more can bond together to form a nucleic acid.

Nucleosides are glycosylamines consisting of a base (or nucleobase) to a ribose (or deoxyribose) ring. Some nucleosides are cytidine, adenosine, guanosine, and inosine. When nucleosides are phosphorylated in cells, they produce nucleotides (see above).

Given the importance of ribose as an essential part of nucleic acids, nucleotides, nucleosides, its role in the production of energy (as ATP), and its ability to increase synthesis and salvage of nucleotides in the body, the inclusion of ribose in a formula designed to provide high levels of nucleic acids appears especially appropriate.

NUTRITIONAL YEAST (1,500 MG PER SERVING)

Nutritional yeast belongs to the same family of organisms as edible mushrooms. It may be considered man’s oldest industrial micro-organism. For more than 50 years, our supplier has been manufacturing primary grown nutritional yeast (Saccharomyces cerevisiae), grown specifically for its nutritional value. After the fermentation process is completed the yeast is harvested, thoroughly washed, pasteurized, and dried on roller drum dryers. The special growth medium and unique drying process are the secrets to the exceptional performance of the nutritional yeast in our product.

The result is a high-quality non-GMO product containing protein (approximately 48%) composed of essential and non-essential amino acids, dietary fiber, B-complex vitamins, and minerals such as selenium, chromium, potassium, magnesium, sodium, copper, manganese, iron, and zinc.

Nutritional yeast is extraordinarily rich in nucleic acids. In fact, nutritional yeast contains approximately 6% RNA among the highest of known foods.

In Dr. Frank’s protocols described in his book Nucleic Acid Nutrition and Therapy he used both nutritional yeast and high RNA extracts of nutritional yeast to obtain healing and regeneration.

Furthermore, nutritional yeast contains additional functional and beneficial components such as beta-1,3 glucan, trehalose, mannan and glutathione. Studies have show that these components have potential health benefits such as, improved immune response, normalization of cholesterol, and cellular normalization properties.

RICE BRAN SOLUBLES (2,000 MG PER SERVING)

Rice bran solubles are one of the most nutrient-dense superfoods available today. They derive entirely from rice. Specifically, they are a highly concentrated soluble carbohydrate and lipid-rich component of stabilized rice bran (i.e., a non-chemically modified water-soluble fraction). They are also a complete, great-tasting, natural source of B-complex vitamins (i.e., thiamin, niacin, vitamin B6) and contain many other nutrients, including amino acids, antioxidants, essential fatty acids, and phytonutrients, rice bran solubles are one of the world’s perfect whole foods, lacking only a few trace minerals.

In fact, our non-GMO rice bran solubles product offers at least 29 vitamins and minerals, and more than 90 antioxidants. Among these are lipoic acid (useful in blood glucose control), tocopherols, and tocotrienols (which may have a positive effect on cholesterol levels).

Alpha tocotrienol has been shown to provide up to fifty times more antioxidant power than alpha tocopherol. Rice bran solubles also contain essential fatty acids, including phospholipids, gamma oryzanol, ferulic acid, and phytosterols.

Certain antioxidants in rice bran solubles are documented as supportive in retarding the aging process and combating fee radicals. They strengthen the body’s ability to regenerate and increase energy and stamina.

Our producer of the stabilized brown rice bran in Rejuvenate! Berries & Herbs utilizes a process that reliably inactivates the lipase in rice bran while retaining the rest of the food’s chemistry. This is done with a mechanical extrusion process that forces the grain to deform as it squeezes through small openings in a metal die. The high rate of deformation during extrusion causes just the right amount of internal heating for the precise amount of time needed to inactivate the lipase. The result is a stabilized rice bran product that retains most of the vital nutrients of fresh rice bran, but has a shelf life measured in years rather than hours.

KEY NUTRITIONAL ELEMENTS IN RICE BRAN SOLUBLES

• Gamma oryzanol, beta sitosteryl ferulate, and five other related compounds. These are potent antioxidants and trace nutrients that play a vital role in many aspects of human physiology. Gamma oryzanol is found only in rice bran and has been used successfully in dealing with female hormone imbalances.
 Tocopherols and Tocotrienols – These include all of the eight known forms of Vitamin E including d-alpha tocopherol. The importance of the other forms is probably at least equal to the alpha form.

• Polyphenols, including ferulic acid, alpha-lipoic acid, and four other polyphenols. Lipoic acid plays an important role in sugar metabolism at the cellular level and is a powerful antioxidant. Ferulic acid also is a powerful antioxidant.

• Important minerals magnesium, calcium, and phosphorous, as well as manganese and other trace minerals. Minerals are involved in all of the enzyme functions of the body including those involved in energy production.

• Phytosterols, including beta sitosterol, campesterol, stigmasterol, and at least eleven more. Phytosterols have been shown to prevent the absorption of cholesterol, support healthy prostate function, and help to build immune function.

• Carotenoids, including beta-carotene, alpha carotene, lycopene, lutein, zeaxanthin, and more. Although beta-carotene is commonly sold as a single-ingredient supplement, alpha-carotene may in fact be more important. Lycopene is responsible for some of the recent health claims relating to tomatoes, and lutein and zeaxanthin play key roles in retinal function.

• Essential amino acids including tryptophan, histidine, methionine, cysteine, cystine, and arginine. Amino acids are the body’s basic materials for building all of its enzymes, DNA, RNA, and connective tissue.

• Nine B vitamins supporting the body’s metabolic machinery, polysaccharides (known among other functions to support immunity), and phospholipids. Phospholipids are vital to maintaining healthy cell membranes.

• Lecithin, which provides the important phospholipids phosphatidyl choline and phosphatidyl serine.

• Seven identified enzymes, including coenzyme Q10 and superoxide dismutase (an important antioxidant).

HIGH PHOSPHATIDE LECITHIN (98%OIL FREE, NON-GMO, FROM SUNFLOWER SEEDS) (1,500 MG PER SERVING)

In recent years, there is renewed interest in the health benefits and dietary requirements of lecithin. Growing evidence now suggests that dietary lecithin is important preventing many pathologic conditions. Lecithin is used as a dietary supplement for purpose of treating or preventing several human diseases, including cirrhosis of the liver, arteriosclerosis, and certain deficiencies of brain function and memory. In fact, the most recent research has shown that lecithin is an essential dietary component for ensuring optimal nutrition.

Lecithin and its component phosphatidyl choline are known to be essential for liver function. In fact, even a few weeks on a choline-deficient diet has been shown to cause abnormalities in liver function. Studies in primate models of alcohol-induced cirrhosis have shown that lecithin protects the body from alcohol liver damage. This is a particularly important finding because liver cirrhosis caused by excessive intake of alcohol is the fourth leading cause of death in people 25–64 years of age in the US.

Lecithin has also been shown to be essential for proper brain development in infants and children. Supplementing animal diets with lecithin at during specific times of brain development has been shown permanently to increase cognitive function.

MAGNESIUM

Magnesium is one of the most abundant, available metals on earth, and plays crucial roles in the sustenance of life and its chemical processes. The divalent nature of the magnesium cation makes it an ideal activator for enzyme systems. Estimates for its usage in human body systems include over fifty different biochemical reactions and its necessary presence for the operation of over 300 enzymes.

Magnesium is essential for energy production, maintenance of electrolyte balance, and neuromuscular function. Investigations into rates of magnesium deficiency show that individuals in developed countries are at remarkably high risk for magnesium deficiency.

The suspected primary cause of this risk for deficiency are inadequate, depleted diets that are high in processed foods (from which magnesium is removed but not replaced).

There are several nutritional requirements in the body in order for mitochondria to manufacture ATP. These essential nutrients include oxygen, magnesium, food substrate, ADP, and inorganic phosphate, as well as Vitamin B1, Vitamin B2, and Vitamin B6 in their phosphorylated coenzyme forms.

The body also needs adequate stores of malate (an important Krebs cycle intermediate) in order for most of these nutrients to function effectively in the process of ATP production. When any of these nutrients are not present in adequate amounts within the mitochondria, a vicious cycle can occur in which ATP is not created in amounts sufficient for proper cellular functioning.

Insufficient amounts of ATP mean that the B vitamins may not be adequately phosphorylated leading to improper metabolism and further reductions in ATP production. The much less efficient anaerobic production of ATP will be utilized to a greater extent in such cases.

A balance point may be reached in which the body produces only a fraction of the optimal amount of ATP. Under these conditions muscle weakness and fatigue may occur.

Abraham and Flechas report that supplementing the diet with magnesium may reverse such conditions of low energy (Jrnl of Nutritional Medicine 3: 49-59).

For the above reasons, we have included magnesium in Rejuvenate! Berries & Herbs from magnesium malate (providing both magnesium and malate) and magnesium ascorbate (providing additional magnesium as well as Vitamin C).

DULSE

Dulse is a sea vegetable (i.e., seaweed) that is a rich source of iron, potassium, iodine, Vitamin B6, riboflavin, and dietary fiber. It provides a wide range of minerals, trace elements, enzymes and phytochemicals, as well as some high-quality vegetable protein. Our certified organic raw dulse is sustainably harvested from well-protected coastal passages and low temperature dried.

FOLINIC ACID

Folinic acid, also known as 5-formyl tetrahydrofolate, is one active form in a group of vitamins known as folates. In contrast to folic acid, a synthetic form of folate, folinic acid is one of the forms of folate found naturally in foods. Folate deficiency is believed to be the most common vitamin deficiency in the world due to food processing, food selection, and intestinal disorders. In the body folinic acid may be converted into any of the other active forms of folate.

Folate coenzymes are responsible for the following important metabolic functions: 1) Formation of purines and pyrimidines which, in turn, are needed for synthesis of the nucleic acids DNA and RNA. 2) Formation of heme, the iron-containing protein in hemoglobin, 3) Interconversion of the 3-carbon amino acid serine from the 2-carbon amino acid glycine, 4) Formation of the amino acids tyrosine from phenylalanine and glutamic acid from histidine, 5) Formation of the amino acid methionine from homocysteine (Vitamin B12 as methylcobalamin also is needed for this conversion). Elevated levels of homocysteine have been implicated in a wide range of health disorders. In the reconversion of homocysteine to methionine the body uses the methionine to make the important amino acid s-adenosylmethionine (SAMe) which is known to be helpful in cases of depression, 6) Synthesis of choline from ethanolamine, 7) Formation and maturation of red and white blood cells, and 8) Conversion of nicotinamide to N’-methylnicotinamide.

METHYLCOBALAMIN (COENZYME FORM OF VITAMIN B12)

Methylcobalamin is one of two coenzyme forms of B12 (along with adenosylcobalamin) and can be used directly by the body without metabolic conversion.

Vitamin B12 is involved in numerous important body functions, including: 1) Red blood cell formation and control of pernicious anemia, 2) The synthesis and function of nerve tissue, such as myelin, 3) The metabolism of carbohydrates, fats, and proteins (Vitamin B12 is necessary for the conversion of methylmalonate to succinic acid, an important Krebs cycle intermediate in energy production), 4) The synthesis or transfer of single carbon units (e.g., allowing the interconversion of serine and glycine and the conversion of homocysteine to methionine), 5) Serving as a coenzyme in the biosynthesis of methyl groups, and 6) Involvement in reactions that convert disulfides (S-S) to the important sulfhydryl group (S-H).

COMPOSITION

REJUVENATE!™ BERRIES & HERBS CONTAINS:

Rice Protein, Vegetable Sprouts Protein (65% protein – organic), Hemp Protein with fiber (37% protein – organic), Flaxseed Powder, Rice Bran Solubles, D-Ribose, Blueberry powder (organic freeze dried), Cranberry powder (freeze dried), Strawberry powder (organic freeze dried), Raspberry powder (organic freeze dried), Nutritional Yeast (brewers yeast), Lecithin (98% oil free, high phosphatide, non-GMO, from sunflower seeds), Xylitol (from organic hardwood), Mannitol, Inulin/fructooligosaccharides (chicory root), VitaBerry Plus, L-Lysine (USP grade), Vanilla Flavoring (organic), Mixed Berry Flavoring (organic), RNA from yeast, Vitamin C (from Mg ascorbate), Chlorella Growth Factor (CGF), Burdock Root (organic), Astragalus Root (organic), Turmeric (organic), Proprietary Enzyme Blend (Protease, Peptidase, Cellulase), Ginger Root (organic), L-Malic Acid, Rhodiola rosea (root) (3% rosavins), k-Rutin™, N-Acetyl-L-Cysteine, Milk Thistle Standardized Extract (82% silymarin), Licorice (root) (organic), Kelp (organic), Dulse (organic), Inositol, Green Tea Extract (95% polyphenols), Dandelion Root (organic), Aloe vera (ActivAloe 200:1 – organic), Vitamin E (d-alpha tocopheryl succinate), Magnesium (from Mg malate), Stevia Leaf Extract, Lipoic Acid, Vitamin B3 (niacinamide), BioVin® Grape Extract, Choline (from bitartrate), Immune-Assist (organic medicinal mushrooms), Pantothenic Acid, Vitamin E (high-gamma mixed tocopherols), Vitamin B5 Pantethine, Germanium Sesquioxide, Resveratrol (from polygonum cuspidatum), Vitamin B6 (Pyridoxal-5′-phosphate), Vitamin B2 (riboflavin-5′-phosphate), Vitamin B1 (thiamin diphosphate), Magnesium (from Mg ascorbate), Biotin, Folinic Acid (from calcium folinate), Vitamin K1 (as phylloquinone), Vitamin B12 (as methylcobalamin), Selenium (from l-Selenomethionine), and Vitamin D3 (cholecalciferol).

BERRIES & HERBS IS ONE OF THREE REJUVENATE! SUPERFOODS

There are three unique superfoods in the Rejuvenate! line. They are Rejuvenate! (Original), Rejuvenate! PLUS, and Rejuvenate! Berries & Herbs. A complete side-by-side comparison of these superfoods is available.

SOURCES & RESOURCES

REVIEWS

“Rejuvenate! Berries & Herbs is Rich in RNA, Plant Proteins” (by Mike Adams, the Health Ranger)

“Rejuvenate!™ PLUS Superfood is High in DNA and RA with Sprouts, Chlorella and More” (by Mike Adams)

“Superfood for Cellular Survival” (by Dr. Mark Sircus)

HPDI BLOG ARTICLES

“9 Things to Know About Rejuvenate!™ Superfoods”

“High-RNA Rejuvenate!™ Superfood”

“Rejuvenate! – The Original, High-RNA Superfood”

“The Amazing Healing Potential of Natural Nrf2 Activators”

Review of Scientific Research on Oligomeric Proanthocyanidins (OPC)

DIETARY NUCLEIC ACIDS – DR. BENJAMIN S. FRANK, PART 1

DIETARY NUCLEIC ACIDS – DR. BENJAMIN S. FRANK, PART 2

Super-Tasty Morning Nutritional Drinks

Superfood Bars with Rejuvenate! Berries & Herbs

BOOKS & JOURNAL ARTICLES

Dr. Frank’s No-Aging Diet: Eat and Grow Younger. Dial Press, 1976.

Nucleic Acid Nutrition and Therapy. Rainstone Publishing, 1977

Nucleic Acid and Anti Oxidant Therapy of Aging and Degeneration. Royal Health Books, 1977.

Nucleic Acid Therapy in Aging and Degenerative Disease–A Metabolic Approach with DNA, RNA, and Related Metabolites. Psychological Library, 1968.

The Problem of Age, Growth and Death. C.S. Minot. Putnam’s Sons, 1908.

“On the influence of nucleic acids of various origin upon the growth and longevity of the white mouse. ” T. Brailsford Robertson. Australian J. Exp Biol Med Sci, 1928, 5: 47–67.

“The effect of yeast nucleic acid on the survival time of 600 day old albino mice.” Thomas Gardner. J Gerontol, 1946, 1: 445–456

“Prolongation of the life span in rats.” Max Odens. J. American Geriatrics Soc., 1973, XXI: 450–451.

INTERVIEWS

Interview with Dr. Hank Liers, Part 1: Nutritional supplements and cellular energy

Interview with Dr. Hank Liers Part 2: High-RNA superfoods

Interview with Dr. Hank Liers Part 3: Chemical sensitivities and chlorella detoxification

Interview with Dr. Hank Liers Part 4: Reversing mass chemical contamination

Interview with Dr. Hank Liers Part 5: Superior nutrition for pet health

PRODUCTS

Rejuvenate! Berries & Herbs

Rejuvenate!™ PLUS

Rejuvenate!™ (Original)

Rejuvenate! Superfoods: Side-by-Side Comparison

Ultimate Protector™ Nrf2 Activator

HPDI FOUNDATIONAL SUPPLEMENTS

Contact Us:

You can reach HPDI by calling 1-800-228-4265, email support(at)IntegratedHealth.com, or visit the retail website: www.IntegratedHealth.com

Health care professionals and retailers can apply for wholesale account, which includes access to the HPDI reseller website: www.HealthProductsDistributors.com

1

NUTRITIONAL APPROACHES SUPPORT THE BODY AGAINST VIRUSES

Dr. Hank Liers, PhD virus nutritional approaches

Fred Liers PhD virus nutritional approaches

“Flu season” is here. It’s hard to escape it—as evidenced by sick friends and coworkers—and maybe yourself or family members. Not to mention exhortations to get flu shots in the media and elsewhere.

Flu indeed dominates health news during the winter. This year it coincides with massive media coverage on the Ebola virus.

Are flu shots worth taking to protect against viral illness? The Centers for Disease Control and Prevention (CDC) admits the flu shot may not be effective this year.

In fact, the flu vaccine may offer offer little protection. There are simply too many influenza strains to cover. This year’s vaccine was in production when CDC realized the vaccine does not include the most virulent strain of the season.

What about protection against other viruses? There are thousands. Yet, there are many things you can do to ensure your body can defend itself.

From a perspective of natural healing, the best—and perhaps only—thing to do to combat viruses is establish good health and strong immunity, and then maintain them.

More specifically, natural nutritional approaches supporting the body against viruses include:

1) Establish solid foundational nutrition and optimal nutrients intake though diet and nutritional supplements

2) Build immunity by natural means, including specific immune-enhancing formulas.

3) Take appropriate natural antimicrobial (e.g., antiviral) supplements, including certain herbs, minerals, amino acids, and other nutrients.

The list of approaches is not comprehensive. There exist other natural means supporting the body against viruses that are not specifically nutritional. For example, infrared saunas, hydrotherapy, and various forms of exercise support strong immunity and optimal health in the body. Many approaches are discussed in the HPDI Rejuvenation Program (see below) other than nutrition.

The Rejuvenation Program addresses various health-building practices, including preventing toxicity and detoxification (including related products like Intestinal Rejuvenation Formula and Hepa Plus) that can powerfully support good health. However, this article primarily focuses on nutritional approaches supporting the body defending itself against viruses.

ESTABLISH POWERFUL NUTRITION SUPPORTING THE BODY AGAINST VIRUSES

Establishing and maintaining good nutrition is perhaps the highest priority item when seeking to build optimal health. The kind of health necessary to keep the body and its immune system strong when exposed to viruses.

Winter Health Tea viruses flu colds

Hot herbal tea blends with cinnamon, turmeric, ginger, and lemon are helpful for winter flu and coughs.

THE HPDI REJUVENATION PROGRAM

HPDI offers ideas and suggestions for establishing and maintaining good health and strong immunity that can help you fight viruses.

Many of the ideas and programs are found in detail in the HPDI Rejuvenation Program. (You will hear a lot about that in this article.)

First and foremost, we believe health begins with diet and nutrition, including Foundational Supplements. This is the first part of the Rejuvenation Program.

HEALTHY DIET: WHOLE FOODS & SUPERFOODS

This article will not address diet in detail. However, the HPDI Rejuvenation Program generally emphasizes a balanced, varied diet, consisting of whole, high-density foods, including many vegetables and other plant foods. It favors organically grown and pesticide- and chemical-free foods. A certain level of raw foods is desirable.

The Rejuvenation Program is not prescriptive about what any given individual should eat. Individuals have different dietary needs depending on many factors, including age, level of exercise, blood type, metabolic type, food sensitivities, etc.

Certainly it is best to avoid consuming processed foods, refined foods, as well as high-sugar and other nutritionally depleted foods. In addition, the foods produced by industrial agriculture (i.e., foods containing synthetic pesticides, herbicides, and genetically modified (GMO) foods are best avoided. In addition, ingredients like artificial colors, flavors, preservatives, as well as deleterious additives, fillers, excipients and other non-nutrients or anti-nutrients.

Important dietary recommendations in the Rejuvenation Program include consuming fresh vegetable juices and smoothies, high-density foods (like chia seeds), and relatively high levels of dietary nucleic acids (like those found in Rejuvenate! superfoods).

In summary, the HPDI Rejuvenation Program recommends:

– A Balanced Diet

– Organic and Wild-Crafted, Nutrient-Dense Whole Foods

– Fresh Juices & Smoothies made with Organic Vegetables, Fruits, and Herbs

– Dietary Nucleic Acids (RNA, DNA) from natural sources like chlorella

– Superfoods, especially Rejuvenate!™ superfoods (high-RNA formulas)

– Sufficient Dietary Fiber (also see Intestinal Rejuvenation Formula)

– Alkaline-Forming Diet (high in plant-based foods)

– Eating Right For Your Blood Type (O, A, B, or AB)

– Appropriate routines for individuals, including exercise, yoga, massage therapy, acupuncture, hydrotherapy, as well as relaxation/meditation/biofeedback.

IMPORTANCE OF FOUNDATIONAL SUPPLEMENTS

What distinguishes HPDI’s Rejuvenation Program from other health and wellness programs,  supplement systems, diets, or detoxification protocols is its emphasis on a complete system of nutritional supplements and a comprehensive approach to supporting optimal health and well-being.

MAJORITY OF PEOPLE NUTRITIONALLY DEFICIENT

Many people take a daily multivitamin or essential fats, for example. Yet, the fact remains most people do not obtain all the nutrition they require either from foods or from supplements. One reason is that many people do not know which supplements or group of supplements they should take that constitutes a complete nutritional supplement program. Or they may not know the deficiencies from which they suffer.

The majority of people are deficient in magnesium, iodine, vitamin D, Vitamin E, B vitamins, nucleic acids, and other critical nutrients. Only a minority of individuals realize they are deficient, and even fewer take advantage of the availability of supplements to correct deficiencies, including those related to diet and nutrition.

HPDI system of Foundational Supplements rests on four pillars: 1) Multivitamins, 2) Antioxidant/Vitamin C formulas, 3) Essential Fatty Acid (EFA) formulas, and 4) Rejuvenate!™ superfoods (providing therapeutic levels of dietary nucleic acids, which Dr. Benjamin S. Frank asserts are nutrients essential for health).

HPDI offers multiple products in each category, all designed to provide high levels of essential nutrients. Among multivitamins, HPDI offers the Mighty Multi-Vite™ as a premier formula, but also offers products like Multi Two Tabs (which more economically provide similar levels of nutrients).

Likewise, HPDI offers Ultimate Protector and PRO-C™ as our premium antioxidant & Vitamin C formulas. Yet, we also offer Buffered-C (tablets) and Vitamin C (ascorbic acid) capsules that offer economy and potency.

foundational supplements viruses

HPDI Foundational Supplements are multivitamins, antioxidants/Vitamin C, essential fats, and Rejuvenate! superfoods.

Dietary nucleic acids are considered by many to be essential nutrients for health. HPDI currently offers three versions: Rejuvenate! PLUS, Rejuvenate! Berries & Herbs, and Rejuvenate! (original greens). Rejuvenate! superfoods are discussed in greater detail in Part Three and Part Four of the HPDI Rejuvenation Program. (Note: Rejuvenate! PRO and Rejuvenate! Strawberry–Peach Protein Plus are not currently available.)

The Greens Continuum Rejuvenate superfoods chlorella RNA viruses

Rejuvenate! superfoods vary in taste and ingredients, but all offer high levels of dietary nucleic acids.

These four types of foundational supplements provide a base for good health by giving the body the nutrients both required for establishing basic health and for supporting optimal health beyond a good diet. That is, they help ensure complete nutrient intake regardless of the type of diet a person consumes.

It is known that established government standards for nutrient intake are minimal at best (i.e., not optimal for human health). In addition, the principle of biochemical individuality shows that different persons require somewhat different levels of various nutrients. HPDI formulas are designed to offer maximal levels of essential nutrients safely and effectively. The intention behind the formulation of HPDI Foundational Supplements is supporting the optimal health of the invididual.

When individuals consumes the four basic foundational supplements, they gain a greater chance of meeting their unique nutritional needs. They also thereby provide the nutrients their body requires not only to sustain itself and create health, but also to defend itself by supporting optimal cell defense and immunity.

Learn more about the HPDI system of Foundational Supplements (http://www.integratedhealth.com/foundational-supplements/foundational-supplements.html).

BUILD STRONG IMMUNITY (AGAINST VIRUSES)

Building powerful immunity depends substantially on how well the body is nourished. That is, how completely the body receives the nutrition required to support its general good health and enable it to defend itself . But that is not all.

When it comes to defending the body against viruses, two specific types of formulas can play important roles beyond diet and foundational supplements. These are 1) immunity building formulas that include specific substances/nutrients known to support a robust immune system and 2) Formulas that include nutrients/herbs/substances acting as antivirals and antimicrobials in the body.

Many specific immune-building formulas/nutrients, as well as formulas acting as antivirals are included among HPDI’s Enhancement Formulas. These formulas include Immune-Assist™ (medicinal mushrooms), olive leaf extract, Cordyceps, Vitamin D3 Plus, Nascent Iodine, Selenium, Zinc, silver (SilverBiotics Polyvalent silver), and magnesium formulas. Some of these formulas are described in detail in Part Five of the HPDI Rejuvenation Program, as well as below.

Other immune-building foods/herbs and antiviral substances like echinacea and garlic are also part of the Rejuvenation Program. For example, echinacea is considered in Part Five, and garlic is discussed in Part Six as its own supporting protocol. Other supporting protocols include hydrotherapy and sauna therapy. Thus, most of HPDI’s immune-building and antiviral type formulas fall into either the category of Enhancement Formulas or Supporting Protocols. In a few cases, certain supplement formulas or recommended foods/herbs both build immunity and act directly as antivirals (e.g., garlic).

Note: there are other important nutrients like glutathione, quercetin, and certain liposomal forms of nutrients (e.g., vitamin C) that we won’t go cover in this article, but that can be useful for immunity against viruses. While this article is not intended to be comprehensive, our goal nevertheless is to provide resources that can help anyone seeking optimal health.

IMMUNE-BUILDING FORMULAS

As mentioned, immune-building formulas in the HPDI system usually fall into the category of Enhancement Formulas. Enhancement Formulas are the “next-level” of defense built upon the Foundational Supplements.

That is, after individuals have established high nutrient intake using foundational supplements, we typically recommend Enhancement Formulas next because of their unique capacities to support and build health.

While not all Enhancement Formulas specifically build immunity, most of them support health in ways that strengthen immunity. (Note: Another category of HPDI supplements is Specific Condition Formulas designed to address a specific problem or issue.)

While there are various immune-building formulas in the HPDI system, we focus on a select few in this article.

SELECTED ENHANCEMENT FORMULAS

IMMUNE-ASSIST™

Medicinal mushroom are proven immune boosters. When various species are combined in a single formula, the product provides the benefits of each type of mushroom. HPDI offers several medicinal mushroom formulas, including Immune-Assist™.

Immune-Assist™ contains a combination of more than 200 different polysaccharides, derived from the enzymatic breakdown of complex organic plant material from six different species of medicinal mushrooms. These include Agaricus blazeiCordyceps sinensis hybrid, Lentinula edodes (shiitake), Grifola frondosa (maitake), Ganoderma lucidum (Reishi), and Coriolus versicolor. Immune-Assist™ contains 500 mg per vegetarian capsule and is made in America using only USDA-certified organic materials.

Immune-Assist™ is similar to other mushroom-based polysaccharides in that it is formulated through an enzymatically activated process whereby complex cross-linked polysaccharides from vegetable sources are converted to biologically active immunomodulators composed of simpler sugars (such as arabinose and xylose). However, Immune-Assist™ offers significant advantages.

medicinal-mushrooms viruses

Immune-Assist includes Maitake, Cordyceps, Agaricus, Lenticula edodes, Coriolus versicolor, and Ganoderma lucidum.

While Immune-Assist™ contains simple polysaccharides, it also contains more complex polysaccharides, including cross-linked beta mannans and beta-glucans, and hetero-polysaccharides which combine both alpha-bound and beta-bound monosaccharides in the same molecule. These complex polysaccharide compounds are not found in earlier-generation, bran-based supplements like AHCC (Active Hexose Correlated Compound). This is the reason Immune-Assist™ shows such a greater range of immuno-modulation bioactivity than AHCC and other bran-based supplements.

Immune-Assist™ contains not only arabinoxylane, but also lentinan, grifolan (Dr. Nanba’s original Maitake D-Fraction), PSK and PSP, and active hemicellulose correlated compound (AHCC). There is about three times more arabinoxylane per dose of Immune-Assist™ than there is in MGN3, and four times more AHCC than in the ImmPower brand of AHCC.

Immune Assist viruses

Immune-Assist™ Daily Formula

Immune-Assist™ truly is a new and unique immune-boosting supplement. It has been tested in a number of different clinical trials. The results of one clinical trial indicate that mixed polysaccharides of medicinal mushrooms protect the hematopoietic (i.e., blood formation) function of bone marrow, induce the action of the digestive tract, boost the immunity of the cells, and increase the activity of the NK cells, LAK cells, and the ratio of Th to Ts cells.

Learn more about Immune-Assist™ (http://www.integratedhealth.com/hpdspec/immune-assist-daily-formula.html)

Another useful mushroom that is contained in Immune-Assist™, but which is effective on its own or used in conjunction with other immune-supporting substances is Cordyceps sinensis. HPDI carries Pure Cordyceps Capsules that can be used to support powerful immunity and provide a wide range of other benefits.

OLIVE LEAF EXTRACT

About a year ago, Fred wrote an extensive blog article title “Olive Leaf Extract: Antimicrobial Health Builder” in which he described many benefits of olive leaf extract (including its antiviral effects), as well as some of my personal experience with this formula. Check out that article for an extensive discussion of the benefits of olive leaf extract.

Olive Leaf viruses

Olive leaf extract exhibits antimicrobial activity.

HPDI’s Olive Leaf Extract formula contains 500 mg of the highest-quality patented olive leaf extract in a vegetarian capsule. This unique patented olive leaf extract is not inactivated by a blood protein due to its precise molecular rotation.

Olive leaf extract has a long history of strengthing health when microorganisms may be present. In recent years, a drug company discovered that in vitro (test tube) an extract from olive leaf (calcium elenolate) was effective in helping to control a very broad range of organisms.

The problem with using it in the body was that once in the blood, a protein combined with it and caused it to be inactivated. An American company in 1995 found that if the active molecule in olive leaf extract was rotated around a specific axis by a precise amount, the blood protein no longer inactivated it.

Olive leaf extract products without this unique molecular rotation are minimally effective in the body because they are inactivated by a blood protein after a short period of time (approximately 15 minutes).

Olive-leaf-extract viruses

HPDI’s Olive Leaf Extract provides molecular rotation for maximal effectiveness.

Many people report higher energy levels when using olive leaf extract. It has been shown to be extremely safe and non-toxic (even in large doses). See Olive Leaf Extract by Dr. Morton Walker for further information on its effectiveness and full range of applications.

Learn more about Olive Leaf Extract (http://www.integratedhealth.com/hpdspec/olivex.html)

Read Fred’s blog article Olive Leaf Extract: Antimicrobial Health Builder (http://www.integratedhealthblog.com/olive-leaf-extract-antimicrobial/)

VITAMIN D3 PLUS

Every week it seems, new studies report more information on the importance of Vitamin D for health. Among its many benefits: immunity boosting effects. Vitamin D has been shown to reduce the incidence of seasonal flu, for example. (See Vitamin D Abstracts in the resources section below.)

But it does so much more. That’s why we include it as an HPDI Enhancement Formula and have designed our own product that includes vitamins A and K2 (as MK-7) known to improve utilization of vitamin D in the body.

Vitamin D3 Plus is an advanced Vitamin D formula providing high-dose Vitamin D3. Vitamin D3 is the natural form of Vitamin D produced in the body from sunlight and is the form best used for therapeutic purposes.

One softgel capsule of Vitamin D3 Plus provides 5,000 IU of Vitamin D3 derived from highly purified and molecularly distilled fish liver oils. In addition, the product contains 1,000 IU of Vitamin A also derived from highly purified and molecularly distilled fish liver oils and 10 mcg of Vitamin K2 from menaquinone-7.

Vitamin D3 Plus includes synergistic nutrients known to enhance absorption and use of Vitamin D3 in the body. These nutrients include Vitamin K2 (menaquinone-7) (10 mcg), which which works together with Vitamin D to help boost bone density, improve cardiovascular health, and boost immunity.

Vitamin D3 Plus also provides 1,000 IU of Vitamin A, a nutrient known to work powerfully with Vitamin D to help create optimal health. As dosages of Vitamin D increase, ideally your dosage of Vitamin A also will increase, and vice versa. The formula also includes natural Vitamin E as an antioxidant.

vitamin d3 plus doctor hank liers original viruses

Vitamin D3 Plus includes vitamins A and K2 (as MK-7).

Vitamin D3 is a fat-soluble vitamin increasingly known as a nutrient essential for health and well-being. Recent studies show that almost all body systems benefit from adequate Vitamin D intake/production. Therefore, it is important that the body receive optimal amounts in order to build the best health.

In fact, recent studies indicate that 5,000 IU of Vitamin D3 is an ideal amount for daily intake. What is notable about this amount is that the body does not gain the full benefits from Vitamin D until it reaches this “threshold” level of 5,000 IU While the body stores Vitamin D, it must first be given an adequate supply.

Vitamin D deficiency currently is a worldwide epidemic with more than one billion people at risk for diseases associated with low Vitamin D status. Vitamin D is proven safe and effective for a wide range of health conditions (see above and below). There are various reasons for this epidemic, including a significant portion of the world’s population living in northerly latitudes (where sunlight is inadequate during many months of the year), sun avoidance, time spent indoors, etc.

Vitamin D3 Plus provides only the Vitamin D3 form of Vitamin D. We avoid the use of Vitamin D2. Vitamin D2 has greater potential for toxicity, poorer absorption, and reduced effectiveness.

Learn more about Vitamin D3 Plus (http://www.integratedhealth.com/hpdspec/vitamin-d3.html)

NASCENT IODINE

Nascent Iodine is the ideal form of iodine, rapidly absorbed and used by the body when taken as a nutritional supplement. Iodine is associated with a wide range of benefits, not limited to supporting thyroid function and regulating metabolism, boosting energy levels (when iodine is deficient), supporting and maintaining detoxification systems and processes, supporting immune system function, fighting infections (natural antiseptic), and many other healthy benefits. Because of its antiseptic properties, it also can be used effectively to purify water for drinking. One drop provides 400 micrograms of Nascent Iodine in a base of certified Biodynamic® grape alcohol.

Biochemically, Nascent Iodine  is consumable iodine in an atomic form rather than a molecular form. It is highly bioavailable as a pure atomic iodine supplement in an energized state. This “charged” state is held by the atom until diluted in water and consumed, whence it gradually loses energy over a 2–3 hour time span. During this time, Nascent Iodine is recognized by the body as the same iodine that is used by the thyroid and is absorbed effortlessly by the body. As noted, this particular form of iodine is unique and well known to offer beneficial effects unlike any other form of iodine.

nascent iodine formula viruses

Nascent Iodine supports immunity, thyroid health, and provides many other benefits.

Partly due to the fact that iodine supports (and is required for) thyroid function, the uptake of adequate amounts of iodine helps the body produce substantial levels of energy for metabolic processes. It is notable that twenty-five percent of the iodide ions found in the human body are found in the thyroid gland.

It is estimated that more than 90% of Americans suffer from a deficiency of iodine. There are many causes for widespread deficiency among the population. Some significant factors include diets lacking in ocean fish or sea vegetables (e.g., seaweeds), high intake of bromine (which is added to commercial breads and baked goods), and vegetarian or vegan diets (see more below), all of which may contribute to lower than optimal levels of iodine.

Moreover, it is known that toxic halides, including chlorine, fluorine (e.g., fluoride in toothpaste), and bromine (e.g., in breads) compete for uptake with iodine in the body, thereby contributing to iodine deficiency.

Iodine deficiency can lead to the development of many adverse health conditions (and a wide variety of symptoms) because the entire body (i.e., all organ systems) depends upon iodine for the critical roles it plays energy production, healthy metabolism, and overall support of health.

The importance of iodine to the biological function of the body traditionally focused on the role of iodine in the nourishment of the thyroid gland, particularly for the production of T3 and T4 hormones, and the regulation of metabolism.

However, as the understanding of this nutrient progresses, we have come to understand that the roles of iodine in the body far surpass those roles it has been believed to fulfill. Iodine is not only necessary for overall health, but also is a crucial component of detoxification processes critical for sustaining life and health.

Learn more about Nascent Iodine (http://www.integratedhealth.com/hpdspec/nascent-iodine.html)

POLYVALENT SILVER

Colloidal silver is a proven antimicrobial. It is highly effective against a broad range of viruses, bacteria, and fungi. It can help you combat these microbes.

HPDI offers a Silver Biotics® product made using a patented method to produce nano-silver particles suspended in a medium of highly purified water. The Silver Biotics® particles have been defined as a metallic nano-silver particle with a thin coating of polyvalent silver oxide.

silver-biotics polyvalent silver viruses

Polyvalent silver supports and maintains health naturally.

The patented production method supercharges the silver particles using 10,000 volts AC, whereas other colloidal silver solutions are typically only charged with 100 volts DC. This supercharging results in 2 electrons being removed from the outer shell of the silver atom giving it a +2 ionic charge compared to a +1 ionic charge for other colloidal silvers.

Because the ionic charge is one of the primary mechanisms by which silver particles work, the Silver Biotics® particles are significantly more effective than conventionally produced colloidal silver.

The patented production method used in creating Silver Biotics® polyvalent silver produces a unique electron configuration that gives the silver particles the catalytic ability to recharge and regenerate themselves over and over again. This gives each silver particle in the Silver Biotics® solution the ability to be used multiple times as opposed to the one time use of the particles produced by most other colloidal silvers.

Research also shows that conventionally produced colloidal silvers have a bioavailability of 15–65%, whereas the Silver Biotics® polyvalent silver has a bioavailability of over 99%. The ability of the Silver Biotics® polyvalent silver particles to be used multiple times along with the high bioavailability means that the Silver Biotics® is significantly more effective than other colloidal silver products even at the lower concentration of 10 ppm.

The silver particle size range in Silver Biotics® is between 0.005 and 0.015 microns. The particles are suspended in a solution of double distilled water. Our manufacturer has chosen a safe FDA approved plastic container for the Silver Biotics®. Research studies have shown that glass containers cause the polyvalent silver particles to plate out or precipitate from solution and reduce the product’s effectiveness by about 50%.

Tests performed at multiple research laboratories have shown that Silver Biotics® is highly effective against a broad range of bacteria, fungi (including Candida albicans), and viruses. Because Silver Biotics® does not target specific mechanisms, receptor sites, or metabolic processes, it is unlikely that mutations of the microbes will produce resistant strains (as antibiotics often do)!

In addition to its antimicrobial properties, Silver Biotics® has been shown to be a potent anti-inflammatory agent. Furthermore, there is powerful evidence that Silver Biotics® improves the state of the body’s immune system.

Silver Biotics® can be applied topically or taken internally. Also, it can be used as a topical disinfectant. Studies have demonstrated that it is highly non-toxic, even at high levels of ingestion (5g/kg of body weight). Furthermore, research studies by major research groups have shown that Silver Biotics® solutions are not cyto-toxic and do not kill friendly probiotic bacteria.

Learn more about Silver Biotics® Polyvalent Silver (http://www.integratedhealth.com/hpdspec/silver-biotics-polyvalent-silver.html)

MAGNESIUM, ESPECIALLY MAGNESIUM CHLORIDE (MgCl2)

Magnesium is one of the most important minerals for health. It offers so many benefits that it would be difficult describe them briefly. However, suffice it to say that magnesium supports immunity, energy (ATP) production, vascular health, and total body wellness. Yet, nearly everyone (greater than 90% of Americans) is deficient.

HPDI offers several types of magnesium supplements. We offer a full range of Ancient Minerals topical magnesium chloride products, including magnesium oil, as well as flakes and gel. We also offer Myo-Mag, a unique combination of magnesium, malic acid, and synergistic nutrients.

Topically applied magnesium chloride formulas are among the most effective at rapidly elevating magnesium levels in the body. Magnesium provides significant health benefits to the body, including immune-boosting effects.

Magnesium dead sea viruses

Magnesium-rich water provides the body with rapidly assimilable magnesium.

Magnesium is necessary for the production of energy (ATP or Adenosine Triphosphate) in the body. When the body receives adequate amounts of magnesium, it can produce the levels of energy required to sustain the body and enable it to thrive. It is precisely because energy (as ATP) is required for the health of human organism that the critical role magnesium plays in energy production is gaining increased recognition by individuals interested in nutrition and natural health. All organ systems depend on energy. A mineral nutrient (i.e., magnesium) that can increase cellular energy thereby has the capacity to improve the health of the entire human body (i.e., all organ systems) via providing the energy for sustaining them all.

Magnesium is critical for cell metabolism. It helps to transport other minerals across cell membranes and affects cell mechanisms controlling muscle and nerve cell activity.

Magnesium specifically is important for the metabolism of many biologically active nutrients and substances, including calcium, potassium, phosphorus, zinc, copper, sodium, lead, cadmium, hydrochloric acid (HCl), acetylcholine, and nitric oxide (NO). It is required for more than 325 magnesium-dependent enzymes, cellular homeostasis, and activation of the B vitamin thiamin. It mediates the functions of the nervous and endocrine systems, supports proper muscle and nerve function, stabilizes heart rhythm, helps to regulate blood sugar levels, and supports normal blood pressure. As noted, magnesium is important in energy metabolism and the synthesis of proteins. The majority of magnesium within the nucleus of cells is closely connected with nucleic acids and mononucleotides. In fact, magnesium helps to maintain the structural integrity of DNA.

Unlike any other form of magnesium, magnesium chloride is a known infection fighter. As early as 1915, the French surgeon, professor of clinical surgery, and French Academy of Sciences member Dr. Pierre Delbet (1861–1957) used magnesium chloride solution to cleanse wounds in soldiers injured during the First World War. He had searched for an antiseptic that could disinfect wounds, but would not damage tissue (and thereby encourage mortification) as did other antiseptics then available. He reported that magnesium chloride was superior to traditional antiseptics not only in its effectiveness in treating wounds, but also because it did not harm body tissues.

Dr. Delbet discovered that magnesium chloride solution increased leucocyte activity and phagocytosis (i.e., the destruction of pathogenic microbes) when applied externally (i.e., used transdermally). He performed numerousin vitro and in vivo studies using magnesium chloride solution. These experiments led to his discovery that magnesium chloride was a potent immune stimulant whether applied externally (i.e., transdermal application), injected intravenously, or taken by mouth (i.e., consumed orally). He termed this immunity boosting effect “cytophilaxis” (a cytophylactic is a substance that protects cells and encourages their healthy growth). In this regard, he observed increased phagocytosis (the engulfing of pathogens by white blood cells) by up to 300 percent. That is, white blood cells were three times more effective at destroying microbes than before administration of magnesium chloride.

The pioneering efforts of Dr. Delbet were followed in the 1940s by fellow French physician Dr. A. Neveu. Dr. Neveu confirmed the immuno-stimulant effects of magnesium chloride, and he successfully tested magnesium therapy for wide range of conditions. These conditions included colds and flu, throat infections of the tonsils and pharnyx, lung and respiratory conditions, gastrointestinal inflammation (stomach flu), skin infections, septic wounds, and many common childhood conditions. More recently, other physicians such as Dr. Raul Vergini in Italy have confirmed the results reported earlier by Dr. Delbet and Dr. Neveu. Dr. Vergini reports excellent results using small quantities of orally administered magnesium chloride solution (2.5 percent magnesium chloride) both for proven applications developed by Dr. Delbert and Dr. Neveu, and for a broad range of other health conditions.

magnesium oil 64 ounces viruses

Magnesium oil provides an ideal means to increase magnesium levels in the body.

Additional benefits of magnesium oil include greater energy, more relaxed muscles (and stronger connective tissues), better sleep, improved mental function, headaches reduced (or eliminated), arterial health, better reproductive function, and better hormonal balance for men and women (and reduced PMS). In addition, magnesium maintains the flexibility of cell membranes for improved intercellular communication, greater uptake of bioactive substances (e.g., micronutrients, neurotransmitters, and hormones), and detoxification of toxins and metabolic waste products. Magnesium oil also acts as an effective full body tonic. Dr. Sircus asserts that transdermal magnesium therapy is among the very best ways to improve human health.

Learn more about topically applied Ancient Minerals magnesium chloride (http://www.integratedhealth.com/hpdspec/magnesium-oil.html)

Magnesium chloride products comparison chart

Myo-Mag synergistic magnesium and malic acid formula.

Other useful minerals for supporting immunity include selenium and zinc. HPDI offers Selenium (from l-selenomethionine) and Double Zinc Plus to cover your needs for these important minerals.

VITAMIN C

Vitamin C is a Foundational Supplement in the HPDI supplement system. That is, we consider it more fundamental than an Enhancement Formula, and so ideally everyone takes Vitamin C daily as part of a set of foundational supplements. I’m discussing it here because it plays a significant roles as immune-booster, and because the body may benefit from additional amounts of Vitamin C as a means of supporting health when fighting viral infection.

If you’re not already taking Vitamin C as part of your daily basic (i.e., foundational) supplements, then be sure either to add it to your supplement regimen or at least increase your intake during times you’re likely to be exposed to viruses.

Never forget the power of Vitamin C to benefit health, including support for strong immunity. Nobel prizewinner Dr. Linus Pauling documented the manifold benefits of this essential nutrient. If you read his research (in his books like How to Live Longer and Feel Better), you will see there is good reason why Vitamin C is classified a “vitamin” because without it we cannot survive.

Tangerine Segments viruses

Vitamin C rich foods include citrus fruits, peppers, and certain berries.

Dr. Pauling extolled the efficacy of Vitamin C in his many books, including How to Live Longer and Feel Better. We highly recommend this highly accessible work (even it that’s the only one you read) as he wrote it for a general audience. Or peruse his landmark Vitamin C and the Common Cold for additional perspective.

We include Vitamin C in our HPDI Foundational Supplement system precisely because of its critical role for basic health, healing, and wellness. HPDI offers a range of Vitamin C products.

These formulas include our premier PRO-C™ super antioxidant formula and Ultimate Protector Nrf2 antioxidant formula. We also offer Buffered C tablets and powder, as well as ascorbic acid capsules.

ultimate-protector-sm viruses

Ultimate Protector Nrf2 activator formula provides vitamin C, antioxidants, and Nrf2 activators.

SUPPORTING PROTOCOLS

The HPDI Rejuvenation Program includes various other means for supporting the body, including the immune system, against viruses and for good health generally.

As noted, one of the Supporting Protocols is the Garlic Program. Yet, other subprograms discussed include hydrotherapy and saunas, massage, acupuncture, and yoga.

We include these because building strong immunity almost always involves more than just diet, nutritional supplements, and a positive outlook. Incorporating various forms of exercise, relaxation, mindfulness and meditation, and traditional healing arts are proven means to support good health. And help to support immunity in ways that can help fight the viruses and other microbes that take advantage of weak immunity and undermine our health.

CONCLUSION

There are many things individuals can do to support powerful immunity that can help protect the body against viruses. In fact, there are many additional nutrients we haven’t discussed here. Suffice it to say that there are many natural nutrients, herbs, and other substances that can effectively support immunity and wellness in the face of exposure to viruses.

SOURCES & RESOURCES

FOUNDATIONAL SUPPLEMENTS

HPDI Foundational Supplements

Why You Need Foundational Supplements

Ultimate Protector and the Role of Foundational Supplements for Health

Foundational Supplements: Rejuvenation Program: Part Four

Vitamin C — An Amazing Nutrient by Dr. Hank Liers

Questions & Answers about Ultimate Protector

Review of Scientific Research on Oligomeric Proanthocyanidins (OPC)

HPDI REJUVENATION PROGRAM

HPDI Rejuvenation Program

RELATED HPDI BLOG ARTICLES

HPDI Radiation Protocol

Why Nutritional Supplements are Vital for Optimal Health by Hank Liers, PhD

Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 1 by Fred Liers, PhD

Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 2 by Fred Liers, PhD

Immune Strengthening using Medicinal Mushrooms by Hank Liers, PhD

Olive Leaf Extract: Antimicrobial Health Builder by Fred Liers, PhD

Vitamin D3 — Superstar by Hank Liers, PhD

A Vitamin Medicine Timeline by Fred Liers, PhD

Vitamin D for Health (Review) by Fred Liers, PhD

Vitamin D Abstracts

BOOKS & READING

How to Live Longer and Feel Better by Dr. Linus Pauling

See HPDI’s List of Recommended Reading

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Immune Strengthening using Medicinal Mushrooms

Dr. Hank Liers, PhDA healthy immune system is required for rejuvenation. Yet, often it is the immune system itself that requires rejuvenating to bring it to a level where it can better support rejuvenation of the entire body. Our Rejuvenation Program therefore builds the immune system and includes supplement recommendations and supporting protocols to accomplish that goal. The most important immune building supplement we recommend is Immune-Assist™, a mushroom complex of six medicinal mushrooms containing polysaccharides that provide a wide range of health benefits.

Other important immune building supplements included in HPDI’s Master Rejuvenation program are echinacea, garlic, olive leaf extract, and astragalus. We will discuss immune strengthening using medicinal mushrooms and Immune-Assist™ in this article. Additional articles (forthcoming) will be dedicated to the other immune-building supplements.

Medicinal Mushrooms Extracts: One of the Most Powerful Immune Modulators

Recent scientific research has shown that medicinal mushrooms grown on vegetable sources (such as millet, rice bran, buckwheat, barley, etc.) enzymatically activate a process whereby complex cross-linked polysaccharides from the vegetable sources are converted to biologically active immunomodulators (also known as biological response modifiers). As you will see from the discussion below, the polysaccharides produced by this process are effective and safe immune stimulants.

shrooms1

 

Medicinal mushroom research has focused on discovering compounds that can positively or negatively modulate the biological response of immune cells. Certain mushroom derived-glucans and polysaccharide-bound proteins have been shown to act as immunomodulators or biological response modifiers (BRMs). A variety of therapeutic effects often occur when these mushroom-derived polymers interact with the immune system to upregulate or downregulate specific aspects of the responses of the host. Whether certain compounds enhance or suppress immune responses can depend on a number of factors including dosage, route of administration, timing and frequency of administration, mechanism of action, or the site of activity.

Many mushroom-derived polysaccharides appear to fit the accepted criteria for BRM compounds. They cause no harm and place no additional stress on the body, they assist the body to adapt to the various environmental and psychological stresses, and they have a non-specific action on the body, supporting all the major systems, including nervous, hormonal, and immune systems, as well as regulatory functions.

The anti-tumor polysaccharides isolated from mushrooms (fruit-body, submerged, cultured mycelial biomass or liquid culture broth) are either water-soluble β-D-glucans, β-D-glucans with heterosaccharide chains of xylose, mannose, galactose, or uronic acid or β-D-glucan-protein complexes – proteoglycans.

While the role of medicinal mushrooms in immunomodulation and anti-cancer activities represents the central theme of much of the conducted research, it is pertinent to observe that many of the medicinal mushrooms have been highly valued for other medicinal properties including hypercholesterolemia, high blood pressure, diabetes, anti-viral, anti-bacteria, and antioxidant and free radical scavenging.

Mushroom-Derived β-glucans are Safe

The safety criteria for mushroom-derived β-glucans have been exhaustively carried out in pre-clinical experiments. Acute, subacute, and chronic toxicity tests have been carried out together with administration during pregnancy and lactation with no adverse effects. There were no anaphylactic reactions and no effects in mutagenicity and haemolysis tests, blood coagulation and a wide range of other regulatory tests.

There was no evidence of genotoxicity. Similar results have been obtained with other β-glucans. When applied to humans in Phase 1 clinical tests, the β-glucans demonstrate remarkably few adverse clinical reactions.

Therapeutic Properties of Medicinal Mushrooms

In the 2001 report Medicinal Mushrooms: Their Therapeutic Properties and Current Medical Usage with Special Emphasis on Cancer Treatments, a wide variety of mushroom polysaccharides, including Lentinan (from L. edodes), Schizophyllan (from S. commune), PSK and PSP (from Trametes versicolor), and Grifron-D (from the Maitake mushroom G. frondosa) and others are described, and their properties are shown to satisfy the criteria for BRMs.

Many of these mushroom-derived polymers potentiate the host’s innate (non-specific) and acquired (specific) immune responses in a similar manner, where they activate many kinds of immune cells that are vitally important for the maintenance of homeostasis. Key innate responses that are stimulated by these mushroom derived-β-glucans or polysaccharide-protein complexes include host T-cells (such as cytotoxic macrophages, monocytes, neutrophils, natural killer cells, and dendritic cells) and chemical messengers (cytokines such as interleukins, interferon and colony stimulating factors) that trigger complement and acute phase responses.

Moreover, mushroom polysaccharides or polysaccharide-protein complexes are considered as multi-cytokine inducers that are able to induce gene expression of various immunomodulatory cytokines and cytokine receptors. In addition, acquired responses are also enlisted, where lymphocytes that govern antibody production (B cells) and cell-mediated cytotoxicity (T-cells) are stimulated. While the immune system is shrouded in tremendous complexity, our current understanding shows that it is regulated in an orchestrated dynamic manner.

Mushroom-derived polysaccharides have shown anti-tumour activities in both pre-clinical models and in clinical trials. Although the mechanism of their anti-tumour action is still not completely clear, Lentinan, Schizophyllan, PSP, PSK and other mushroom polysaccharides appear to mediate their anti-tumour activity by activation or augmentation of the host’s immune system (via stimulated cytotoxic macrophages, cytotoxic T-cells and antibody-mediated cytoxicity of targeted cancer cells), rather than direct cytotoxicity.

Thus, both cell-mediated immune responses against the target T-cells initiated by macrophage-lymphocyte interactions and cytoxicity induced by antibodies to target T-cells are believed to contribute to the elimination of targeted tumour cells. Recent evidence suggests that several mushroom polysaccharides may also possess cytotoxic properties. Grifron-D from G.fondosa mushroom was reported to induce apoptosis (programmed cell death) in human prostate cancer cell-lines.

IMMUNE-ASSIST™ Incorporates Polysaccharide Extracts from Six Organically Grown Medicinal Mushrooms

In China, Japan, Korea, and more recently in the US, hundreds of mushroom species have been studied during the past 20 years. Extracts from most of the medicinal mushrooms show a common property of enhancing immune function by modulating cell-mediated immunity. Simply put, such mushroom extracts seem to turn on cells in the immune system, which appear to have significant disease-fighting properties. In fact, three different anticancer drugs extracted from mushrooms have been approved by the Japanese equivalent of FDA (that is, the Japanese Health and Welfare Ministry). These three are lentinan, derived from shiitake; PSK, derived from coriolus versicolor; and schizophyllan, derived from suehirotake.

Based upon a a large amount of research, a US-based company has formulated Immune-Assist™ , which includes a combination of more than 200 different polysaccharides, derived from the enzymatic breakdown of complex organic plant material from six different species of medicinal mushrooms. These include Agaricus blazei, Cordyceps sinensis hybrid, Lentinula edodes(shiitake), Grifola frondosa (maitake), Ganoderma lucidum (reshi), and Coriolus versicolor.

Immune-Assist™ contains simple polysaccharides similar to many other products on the market, but it also contains much more complex polysaccharides like the cross-linked beta mannans and beta-glucans, as well as hetero-polysaccharides which combine both alpha- and beta-bound monosaccharides into the same molecule. This is the reason that Immune-Assist™ shows such a greater range of immuno-modulation bioactivity than other bran-based supplements. Included among the important substances in Immune-Assist™ are Arabinoxylane, Lentinan, Grifolan (Dr. Nanba’s original Maitake D-Fraction), PSK and PSP, and Active Hemicellulose Correlated Compound (AHCC).

Below we provide a brief summary of the research and clinical studies for each of the mushrooms contained in Immune-Assist™:

Shiitake is now the most popular and most cultivated exotic mushroom in the world. In China, shiitake has a history that dates back to the Ming Dynasty (1368–1644 ACE). The mushroom was used not only as a food but was taken as a remedy for upper respiratory diseases, poor blood circulation, liver trouble, exhaustion and weakness, and to boost chi, or life energy.  It was also believed to prevent premature aging.  Today the shiitake is recognized for its antitumor action and has been extensively researched in regard to its immunologic activity. The initial antitumor research was performed in 1969 by Tetsuro Ikekawa at Purdue University, along with colleagues at the National Cancer Center Research Institute in Tokyo. The researchers found that water extracts of shiitake produced high rates of tumor inhibition in mice (72–92%). Ikekawa later identified a polysaccharide in shiitake called lentinan as having powerful antitumor activity.

Coriolus (or Trametesversicolor is the most thoroughly clinically researched mushroom. An extract of Coriolus versicolor known as PSK is sold in Europe and Japan. It is the best-selling cancer drug in the world and recently accounted for more than 25% of Japan’s total national expenditure for anticancer agents. In addition to possessing many different antitumor properties, it is also an immunostimulant; demonstrates anti-viral activity; enhances T-cell proliferation; and has been shown to improve both disease-free and survival rates in cancer patients. In an 8-year clinical test of breast cancer patients, and in another 5-year study, it was shown that the polysaccharide compounds contained within Coriolus versicolor work particularly well as an adjuvant for cancer therapies, exhibiting diverse biological activities.

Maitake may be even more potent than any of the other mushrooms previously studied. This legendary giant mushroom has been studied for its anticancer, anti-diabetic, anti-hypertensive and anti-hyperlipemic effects since the mid-1980s. Its anti-HIV activity in vitro was demonstrated in tests conducted by the Japan Institute of Health and the US National Cancer Institute in early 1992. Among various extracts obtained from the Maitake mushroom, a specific extracted fraction named Maitake D-fraction is the active constituent. This extract contains beta-1, 3-glucans and beta-1, 6-glucans protein-bound polysaccharides. It has demonstrated remarkable antitumor activity by activating the immune system through oral administration.

The Chinese people have long used Cordyceps sinensis to promote overall good health, and modern research indicates that it does indeed support liver, kidney, heart, and immune system function. Cordyceps sinensis has been used to protect the bone marrow and digestive systems of mice from whole body irradiation. One experiment noted that Cordyceps may protect the liver from damage. An experiment with mice indicated the mushroom may have an anti-depressant effect. Researchers have observed that Cordyceps has a hypoglycemic effect and may be beneficial for people with insulin resistance. Cordyceps mushroom extracts have been shown to stimulate the number of T helper cells, prolong the survival of lymphocytes, enhance TNF-alpha and interleukin 1 production, and increase the activity of natural killer cells. One study indicates that cordyceps can stimulate progesterone production in animal cells. Another study has shown that cordyceps may be effective against tumor cells by down-regulating MHC class II antigen expression. In addition, historical use data suggests that cordyceps can cause a reduction of cyclosporin and aminoglycoside-induced renal toxicity.

Reishi possess anti-tumor, immunomodulary, and immunotherapeutic activities, supported by studies on polysaccharides, terpene, and other bioactive compounds isolated from fruiting bodies and mycelia of this fungus. It has also been found to inhibit platelet aggregation, and to lower blood pressure (via inhibition of angiotensin-converting enzyme), cholesterol and blood sugar. Laboratory studies have shown anti-neoplastic effects of fungal extracts or isolated compounds against some types of cancer. In an animal model, Reishi has been reported to prevent cancer metastasis, with potency comparable to Lentinan from shiitake mushrooms. The mechanisms by which Reishi affect cancer may target different stages of cancer development include: 1) inhibition of angiogenesis (formation of new, tumor-induced blood vessels created to supply nutrients to the tumor) mediated by cytokines, 2) cytotoxicity, 3) inhibition of migration of the cancer cells and metastasis, and 4) inducing and enhancing apoptosis of tumor cells. Besides effects on mammalian physiology, Reishiis reported to have anti-bacterial and anti-viral activities. Reishi is reported to exhibit direct anti-viral effects with the following viruses: HSV-1, HSV-2, and influenza.

Agaricus blazei is an edible mushroom native to Brazil and cultivated in Japan and the USA for its medicinal uses. It has been used to treat arteriosclerosis, hepatitis, hyperlipidemia, diabetes, dermatitis, and cancer. In vitro experiments and studies done in mice have shown that Agaricus has immunomodulatory, antitumor, and antimutagenic properties. The polysaccharides and anti-angiogenic compounds present in Agaricus are thought to be responsible for its antitumor properties. Such effects are believed to be exerted by immunopotentiation or direct inhibition of angiogenesis. A recent randomized study showed that oral administration of Agaricus extract improved the natural killer cell activity and quality of life in gynecological cancer patients undergoing chemotherapy. Agaricus was also shown to have antidiabetic effects in vitro and in animal studies. In addition, results from a study done in human subjects with type 2 diabetes suggest benefits of Agaricus extract in improving insulin resistance, and a pilot study indicates that Agaricus extract may reduce weight, BMI, body fat, and serum glucose and cholesterol levels in healthy individuals.

AHCC as a Component of Immune-Assist™ Daily Formula

AHCC is produced by from the enzymatic action of vegetable sources with mycelial extracts from several different mushrooms. There is about four times more AHCC in each dose of Immune-Assist™ than there is in other AHCC products on the market.

AHCC is a food substance that contains a broad range of polysaccharides. It is believed that a special polysaccharide with a molecular weight of about 5,000 and an alpha 1,4 glucan linkage in this mushroom extract is primarily responsible for the powerful immune enhancing effects on natural killer cells. A heavier polysaccharide in the extract appears to have a powerful stimulating effect on macrophages which, in turn, further stimulates the immune system including a number of cytokines (Interleukin-2, Interleukin-12, Tumor Necrosis Factor [TNF], and Interferon).  Furthermore, some research has indicated that components of AHCC may have direct cytotoxic effects on cancer cells and prevent metastases from occurring.

Natural Killer Cells

The human immune system is comprised of more than 130 subsets of white blood cells. Natural Killer (NK) cells make up roughly 15% of all human white blood cells. They provide the first line of defense for dealing with any form of invasion to the body. Each NK cell contains several small granules that act as chemical destroyers. Once an NK cell has recognized a cancer cell, for example, it attaches itself to the cell’s outer membrane and injects these granules directly into the interior of the cell. The granules then destroy the cancer cell within five minutes. The undamaged NK cell then moves on to other cancer cells and repeats the process. When the immune system is particularly strong, active NK cells will often take on more than one cancer cells or other infected cells at the same time.

NK Cell Activity, Not Number, Determines Immune System Strength

Unlike other white blood cells, inadequate numbers of NK cells are very rarely a problem. Instead, it is the activity of the cells that generally determines whether one is sick or healthy. As long as the NK cells are active, everything remains under control. If NK cells lose their ability to either recognize or destroy the invader, however, the situation can deteriorate rapidly. In AIDS and cancer patients, NK cell activity is probably the primary criteria for estimating the chances of survival. It’s commonly accepted that when NK cells cease to function, the end is near.

In addition, research has now confirmed that individuals with low NK cell activity are significantly more susceptible to autoimmune diseases, chronic fatigue syndrome, viral infections and the development of cancerous tumors.

Doctors can test NK cell activity with a test called the NK cell function test. Basically, a blood sample is taken from the patient and placed in a vial containing live tumor cells. After four hours, a count is taken to determine what percentage of the cancer cells have been destroyed by the NK cells. The higher the percentage, the more active the cells. This test is referred to as the 4 hour Chromium-release assay. Your doctor can order the test from Immune Sciences Lab in Beverly Hills, CA at 310-657-1077.

How IMMUNE-ASSIST™ Increases NK Cell Activity and Immunity

The capacity of Immune-Assist™ to boost NK activity and overall immunity appears to stem from the following:

1) Immune-Assist™ increases the number of explosive granules in NK cells. The more granules an NK cell carries, the more cancer and virus-infected cells it can destroy,

2) Oral ingestion of Immune-Assist™ can increase NK activity as much as 300% (or even higher),

3) It increases interferon (IFN) levels. Interferon is another potent compound produced by the body that both inhibits the replication of viruses and other parasites and increases NK cell activity,

4) Immune-Assist™ increases the formation of Tumor Necrosis Factors (TNFs). TNFs are a group of proteins that help destroy cancer cells,

5) It increases number and the activity of other lymphocytes, especially T-cells (up to 200%) and macrophages,

6) It stimulates cytokine (IL-2, IL-12, TNF, and IFN) production, which stimulates immune function.

Applications for Immune-Assist™

Applications for Immune Assist™ include: 1) recurrent infections, such as colds, flu, and parasites, 2) gum disease, 3) heart disease, 4) peptic ulcer, 5) cancers, 6) slow healing wounds, 7) digestive problems, 8) AIDS, 9) hepatitis, 10) multiple sclerosis, and 11) autoimmune illnesses. Immune Assist™ has not exhibited side effects and is completely non-toxic even after years of use at therapeutic levels.

Owing to its tremendous immune enhancing effects, Immune-Assist™ is likely to be of significant benefit to individuals suffering from a wide range of conditions. Impaired immunity is a result of a wide range of poor lifestyle habits including high stress levels, exposure to high levels of toxins, and poor nutritional status.  As such individuals in the following categories could also benefit from Immune Assist™:

  • Individuals who constantly work with paint (artists, house painters, etc)
  • Chemical and refinery workers and others exposed to heavy doses of toxic chemicals
  • Heavy smokers
  • Heavy drinkers
  • Individuals with gum disease
  • Individuals with peptic ulcers
  • Individuals with prostate infections
  • Individuals with chronic fatigue syndrome
  • Individuals with diabetes
  • Individuals with heart disease
  • Individuals experiencing autoimmune deficiencies (multiple sclerosis, lupus, rheumatoid arthritis)
  • Individuals with recurrent infections, such as colds, flu, yeast, and parasites
  • Individuals whose families exhibit a significant history of cancer
  • Individuals with slow healing wounds

Immune-Assist™ Dosages

Immune AssistThe dosages used in studies are scientifically based on repeated NK cell activity tests. As such, they are consistent and easy to follow. They fall into two types:

1) For cancer, HIV or other life-threatening condition, take three grams per day for two-to-four weeks, then one gram per day until the problem is resolved. Some people continue to take the maintenance dosage even after the problem has been resolved, while others stop taking it and resume if the problem returns. In rare cases taking as much as six grams daily was necessary.

2) As a form of prevention take one gram per day.

In all of the studies, it has been found that taking 3 grams a day resulted in a dramatic increase in NK cell activity within one to two weeks. At the lower dosage of only one gram per day, the same activity wasn’t reached until about four weeks. Thus, the initial heavy doses of three grams per day.  Even after the dosage is dropped back to one gram per day, NK cell activity will continue to increase.  It is best to take the Immune-Assist™ capsules with meals in divided doses.  For example, when taking three grams per day (which works out to six 500 mg capsules), two capsules can be taken with each meal. When you reduce the dosage down to one gram a day (two capsules), you can take one capsule at breakfast and one at dinner.

Conclusion

The importance of a strong, adaptable immune system cannot be underestimated, especially in the context of building (or rebuilding) health and for successful rejuvenation. While there are other useful immune building supplements (e.g., echinacea, garlic, olive leaf extract), Immune Assist™ is highly effective for boosting immunity as part of a complete program for rejuvenation.

Learn more about Immune-Assist™ on the HPDI website.

Sources

1) Healing Mushrooms by Dr. Georges Halpern, MD, PhD., 2007, http://www.alohamedicinals.com/HealingMush_Private_10-18-06.pdf

2) Medicinal Mushrooms: their Therapeutic Properties and Current Medical Usage with Special Emphasis on Cancer Treatments. 2001

Authors: JOHN E SMITH BSc MSc PhD DSc FIBiol FRSE Emeritus Professor of Applied Microbiology, University of Strathclyde Chief Scientific Officer, MycoBiotech Ltd, Singapore. NEIL J ROWAN BSc MSc PhD MIBiol MIFST Lecturer, Department of Bioscience, University of Strathclyde, RICHARD SULLIVAN BSc MD PhD Head of Clinical Programmes, Cancer Research UK.

To download this book go here:
http://ebookee.org/Medicinal-Mushrooms-Their-therapeutic-properties-and-current-medical-usage-with-special-emphasis-on-cancer-treatments-Repost-_1794652.html

3) Anti-Cancer Properties: A peer-reviewed article by Dr. Solomon Wasser of University of Haifa, Israel : Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides