Fred Liers PhD restore liquid mineral supplement gut healthHeard of RESTORE liquid mineral supplement? If not, you’re about to discover something important for gut health.

RESTORE™ is formulated to help restore gut health. It works by strengthening the integrity of tight junctions in your intestinal wall.

Maintaining tight junctions is important because they protect your body from substances entering the blood stream. Restore also supports the communications systems of the bacteria in your microbiome.

Tight junctions are natural barriers protecting the lining of your gut barrier, organs such as kidneys and heart, and the blood-brain barrier thereby keeping out unwanted substances. Even as we take in nutrients from the GI tract, the function of tight junctions is maintaining the integrity of the gut wall and other barriers that protect the body.

These days, our gut membrane has a tough job keeping out unwanted substances. Because tight junctions are weakened by many things, including highly processed foods, especially those containing gluten and gliadin, the herbicide glyphosate (the primary ingredient in RoundUp weedkiller), and other exposures like electromagnetic fields (EMF) from digital devices and Wi-Fi networks.

As a result of weakened tight junctions, undesirable substances from food proteins, harmful chemicals and other toxins can slip though into our bloodstream. This can lead to a powerful immune response that can weaken immunity and cause significant inflammation. Foreign substances in the bloodstream can also result in extreme food allergies and food sensitivities to various toxins entering the body.

We live in an age in which our microbiome health is under assault. Studies show our ancient ancestors had 20,000–30,000 different strains of beneficial bacteria in their GI tracts. Many people today have just 5,000 or less. Why is that?

There are many reasons for low microbiome diversity. These reasons include antiobiotic use (both from pharmaceuticals and foods), glyphosate (which essentially acts like an antibiotic), processed foods (especially those containing gluten and gliadin), and systemic degradation of the gut environment rendering it less hospitable for maintaining health populations of gut flora.

These impacts are significant because diversity in your microbiome not only supports gut health, but also appropriate brain health, immune system health, and overall vitality. Restore acts as a “microbiome fertilizer” helping establish and maintain healthy microbiota.

In fact, Restore contains important “redox” molecules produced millions of years ago by existing soil bacteria. These molecules are an important part of communications systems within the body between gut bacteria and with the body’s mitochondria. These communication systems play an important role in establishing proper homeostasis throughout the body.


There are important reasons to try Restore—whether or not you experience significant gut health issues. These reasons include:

• Maintaining strong tight junctions for mega membrane health, and helping the body restore tight junction integrity

• Creating an environment in which beneficial bacteria can thrive

• Boosting microbiome diversity

• Healing the gut

• Mitigating the adverse effects substances like antibiotics, gluten/gliadin, glyphosate, and GMOs on microbiome health

• Supporting immune system function

• Protecting integrity of blood-brain barrier

Other benefits include support for respiratory wellness, enhancing mental clarity, and promoting proper homeostasis throughout the body.

For all these reasons and more, you should consider taking Restore. You can start by taking one teaspoon or less daily, and gradually increasing your dose to one tablespoon or more.Restore for gut health liquid supplement

I have taken Restore daily for more than two years, and benefit greatly from it. The most noticeable effects are a complete cessation of spring allergies (after two decades of worsening symptoms), greater clarity of thinking, and improved overall well being. I have seen other people get good results with a variety of conditions from dysbiosis to gluten/gliadin sensitivity.


You can learn more about Restore on our website. Also, the Restore website offers in-depth information and videos. Here is how the Restore website and Dr. Zach Bush describe the formula:

Restore is a dietary supplement supplying first line defense against daily exposure to environmental and food-borne factors. It helps create an optimal environment or ecology in the gut membrane for beneficial or “good” bacteria to flourish. Beneficial gut flora protect your immune system and maintain health. Restore is a scientifically proven soil-derived mineral supplement designed to support protection of the intestinal walls.

Restore protects the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten, and food-borne toxins. It helps create an environment in which 20,000–30,000 different strains of beneficial gut bacteria can thrive. This is a far different mode of action from probiotics, most of which contain just 3–30 strains of beneficial bacteria.

Restore helps create a strong immune system along with proper gut function. Microbiome balance and tight junction integrity are known to constitute a significant part of the immune system. They directly affect DNA transcription of cells to promote optimal health and prevent a leaky gut syndrome, thereby improving gut intelligence.

Seventy percent (70%) of our immune system is found in our gut. We need tens of thousands different strains of good gut bacteria to support a healthy immune system. Clinical experience, in addition to cell culture studies, support the theory that Restore’s proprietary formula creates the optimal environment in the gut to create a tight junction barrier and maintain our health and wellness.

Restore is a daily liquid supplement designed to support the protection of the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten and food-borne toxins by helping to create an environment where between 20,000-30,000 different strains of good gut bacteria thrive. Most probiotics on the market contain fewer than 24 different strains of good gut bacteria.


Restore is ideal for individuals suffering from gut health issues. Yet, it is also excellent for supporting and maintaining gut health generally. That is the reason we at HPDI consider Restore important enough to designate as a foundational supplement, one of the top six supplements you need for good health.

Given the safety and effectiveness of Restore, there is broad applicability for its use. This is especially true because gut and microbiome health are under constant assault. These assaults range from multiple environmental and lifestyle factors—including poor diets high in processed foods, antibiotics in pharmaceuticals and animal foods—to massive glyphosate (herbicide) contamination of foods, soils, air, and water.

Let Restore be your first line of defense against assaults on your gut health, tight junctions, microbiome diversity, and immune function. As it says on the bottle, “Complete well-being begins in the gut.”


Gut Health – Effects of Glyphosate and Antibiotics
by Hank Liers, PhD and Fred Liers, PhD

Restore – 32 oz

Restore – 8 oz

HPDI Gut Health Formulas

HPDI Foundational Supplements

Restore blog (Restore4Life)



Fred Liers PhD nutritional supplements tips tricks daily routineToday I’m sharing my strategies for taking nutritional supplements in an easy,  organized way, and helping ensure you take them daily. I don’t like the word “compliance” because it implies doctor’s orders. Consider my ideas “hacks” instead, for establishing a daily routine.

My goal is making your daily supplement routine simpler. That is, a hassle free, “no brainer” routine that guarantees you take the vitamins, minerals, essential fats, and other supplements you need. At least the most important ones.


Getting out of the house with a good breakfast is hard enough. Nutritional supplements have a way of being forgotten first. That is, unless and until you have a system: a set of strategies for success to ensure a daily routine.

I’ve been working on my “system” for 30 years. It works for me and many others I’ve shared it with. So I’m sharing it with you. But you don’t need to adopt my system or strategies. Watch the video, take what you like, and make it your own. Craft a system that works for you.

My idea is to inspire and show you it’s possible to dummy proof your supplement regimen to never “miss a dose”—or almost never. No matter how busy you are, how rushed you feel, or how often you tend to forget things. You can do this.



One of the most important things to consider when establishing or creating a regimen for taking supplements is to make sure your supplements are visible. That is, not hidden in a place that allows you to forget to take them. Like the bathroom. Or your garage. Bad places for supplements in general, unless you’re storing them for future use, or want them to expire.

Making your supplements visible means putting them in a place where  you can see them. Get them out of your bathroom or closet and put them in your kitchen area where you will remember to take them. Recall that nutritional supplements are “food supplements,” right?

The kitchen is best for ensuring you take your supplements. If your kitchen can’t be home to your supplements, then other visible places might include the dining area (or where you eat) or possibly your pantry (or where you keep foods). The top of the refrigerator is surely an unused shelf space you cannot miss.

Another option is keeping visible the primary supplements you take, such as multivitamins, Vitamin C, essential fats, or other high-priority supplements. Then keep less important supplements available, but not in a way that clutters counters or other spaces. By prioritizing this way, you at least ensure the visibility of your most important supplements.

The main thing: If you can see your supplements, you are far more likely to take them, and maintain your daily routine. The kitchen is an ideal place. Because if you can’t see them, you won’t take them.


After your nutritional supplements are in your kitchen or in an easily accessible—and hopefully prominent place, then consider organizing them. And noted, I often suggest using the top of the refrigerator since they won’t take up counter space, yet remain visible. Other strategies for organizing and saving space are using small shelves or rotating stands, like lazy susans, as shown in the video above. Or a small basket.

If you must put your supplements away, such as inside a cabinet to save space or for aesthetic reasons, then try to use a kitchen cabinet that is central and easily accessible. And if you use a shelf, lazy susan, or basket, then set it up so you can easily reach the shelf or grab the basket.

The main thing: Keep supplements organized for quick and easy access. This smooths the process for actually taking them. You will be glad you did. Your body and mind will thank you.


Your supplements are visible and organized. Now what? Containerize.

Containerizing is not just for your basket or shelf of supplements. It is also for your daily doses. That is, I suggest you set your daily doses out in advance when possible. This helps simplify your day. You can “take” your vitamins without having to think too much. You can just “grab and go.”

The system I use—and demonstrate in the video—relies on small pyrex cups. You can also you small bowls or paper cups, or any small containers you like.

I use one cup per dose, and I usually break up my supplements into two doses per day (morning and early evening), so I use two cups per day.

I like pyrex cups because they stack neatly and don’t take up much counter space. They are portable, so you can pick up a cup (one dose) and carry it with you.

After your doses are prepared, set them out in a place where you will see them—like the kitchen counter or dining room table. Somewhere where you are most likely not to forget them.

The main thing: Divide your supplements into daily doses or sub-doses you can take when you’re ready. It’s much easier to take them when your doses are made in advance. You will win medals from the Supplement Compliance Club.


After your doses are set out for a day or two—or an entire week—they will be ready and waiting for you. For people who work outside the home or who are traveling, transfer your supplements to portable containers. This might be snack bags (as in my video), but it could be a special box or baggie that holds individual doses.

If I plan to travel or leave for work, I often bag my supplements and place them in my suitcase or car the night before. This ensures I don’t forget them.

For travelers in a pinch, you can put all supplements for say, a week, in a single container, and then divide them up daily. That’s not my ideal, but I’ve seen it work for people who won’t containerize every dose before traveling.

The main thing: Scientific studies prove that having your daily supplements pre-bagged improves your chances of taking them by 1000% when traveling. Pre-bagging makes getting your daily dose so easy, you can think about other things, like where you will go next.


Maintain your supplement routine. Doggedly. A routine can take time to establish. After you get one started, stick to it like a bee on honey.

If you make your supplements visible, then organize, containerize, and bag them for travel, you will never miss a dose. You will guarantee compliance by implementing these simple “hacks.” Then watch as your health improves and you feel better. Like Superman or Superwoman. Be prepared to jump over buildings in a single bound. ~


The Truth About Essential Fatty Acids

Dr. Hank Liers, PhD essential fatty acidsMany in the field of nutrition have lost sight of the fact that there are two essential fatty acids needed by the body. Many people recommend omega-3 fatty acids assuming the the body gets sufficient omega-6 from the diet. The truth about essential fatty acids is more complicated. This article will show the more complete and correct picture.


Fatty acids are part of the lipids class, widely found in nature, food, and organisms. These fatty acids are a critical constituent of the cell membranes in all of the trillions of cells in the body. They have important biological functions including structural, communication, and metabolic roles, and they represent an important source of energy. Their metabolism produces a huge quantity of adenosine triphosphate (ATP). The beta-oxidation of the fatty acids is a well-known process, mostly used by the heart and the muscular tissue to obtain energy.

Figure 1 below shows a schematic diagram of what a fatty acid looks like. One end of the structure in all cases has a carboxylic acid group (COOH) and the other end in all cases has a methyl group (CH3). Saturated fats have single bonds (-) between all carbon atoms (C), but unsaturated fats have a number of double bonds (=) between some of the carbon atoms.

essential fatty acids

Figure 1 – Basic diagram of fatty acids structure

The human body can synthesize many of these fatty acids, except the essential fatty acids (PUFAs) linoleic acid (LA) and alpha-linolenic acid (ALA). These two are generally found in various vegetable oils, but their important metabolites are found mainly in special vegetable oils such as borage oil and in fish oils. Linoleic acid is the most abundant fatty acid in nature, and it is the precursor of other omega-6 fatty acids. Omega-3 fatty acids are synthesized from alpha-linolenic acid.

Once ingested, short-chain PUFAs are converted to long-chain fatty acids. These are critical for mammalian cells in order to perform various biological functions, such as sustaining the structural integrity of cellular membranes and serving as signaling molecules. They are highly enriched in brain tissues, where they participate in the development and maintenance of the central nervous system during both embryonic and adult stages.

Polyunsaturated fatty acids have been extensively researched. They include the essential fatty acids linoleic acid (an omega-6) and alpha linolenic acid (an omega-3). Omega-3s are not abundant in our food chain. There is none in corn oil and very little in soy oil, the two most widely used food oils. Therefore, nearly all the early research with polyunsaturated oils utilized omega-6 fatty acids, predominantly as linoleic acid.

Fish oils were neglected out of ignorance or because the investigators chose to pass over these cholesterol-containing oils. Concern eventually developed over the close association between increasing incidence of mammary tumors and high intake of omega-6 polyunsaturated fatty acids. After some years, researchers finally turned their investigations to the interrelationship between dietary omega-6 and omega-3 fatty acids.


The following diagram shows in detail the pathways for the production and use of fatty acids in the body. In the figure the metabolic pathways (running left to right) for four fatty acids types are shown (top – Omega-3, second – Omega-6, third – Omega-9, bottom – Omega-7). Notice that only the omega-3 and omega-6 oils are considered to be essential fatty acids because they cannot be made in the body. This means they must come from food.

essential fatty acids

Figure 2 – fatty acid metabolism pathways in the body

The diagram shows a series of enzyme induced reactions that either add a double bond or two additional carbon/hydrogen pairs to the fatty acid. The enzymes that make this happen are called desaturase and elongase. The desaturase enzymes are given a number for the carbon number (that the enzyme is working on) from the methyl end of the fat. These same enzymes work on all of the fatty acid types. For example, Delta 6 desaturase causes an additional double bond to be inserted into both alpha-linolenic (omega-3) and linoleic acid (omega-6) (as well as oleic acid and palmitoleic acids).

In this way, the body is able to produce a wide variety of fatty acids that have their own unique effects on biochemistry. Some of these are more important than others. In particular, the omega-3 essential fatty acid eicosapentanoic acid (EPA), the omega-6 essential fatty acid dihomo-gamma-linolenic acid (DGLA), and the omega-6 essential fatty acid arachidonic acid (AA) are precursors for a class of chemicals called eicosanoids/prostaglandins that have far reaching affects on key body functions.


Eicosanoids are prostaglandins that affect many aspects of health both positively and, in some cases, negatively. All known eicosanoids and prostaglandins are formed from the essential fatty acids linoleic acid (omega-6, or n-6), alpha linolenic acid (omega-3, or n-3), their “enhanced” derivatives, and from the omega-3 fatty acids in fish oils.

Prostaglandins are short-lived highly active, hormone-like chemicals that are found in every cell of the body. They are regulators of cell activity and essential for maintaining health. Each cell type or organ produces its own form of prostaglandin to carry out its functions. There are three types of prostaglandins: PG1, PG2, and PG3.

Series 1 Prostaglandins (PG1), derived from gamma-linolenic acid (GLA), the active component of borage oil, has many beneficial effects: It makes platelets less sticky, lowers blood pressure by relaxing smooth muscles in the walls of arteries, increases loss of sodium and water, decreases inflammation and enhances immunity.

Series 2 Prostaglandins (PG2), also derived from GLA, is used in “fight or flight” (stress) situations, – the fight against danger, or the flight from it. In modern lifestyles which are high in stress but low in physical activity, continuous production of Series Two Prostaglandins results in sticky platelets, high blood pressure, increased water and sodium retention, increased inflammation and decreased immune system capabilities.

Series 3 Prostaglandins (PG3), derived from eicosapentaenoic acid (EPA), the active component of fish oil, has beneficial effects. They block the detrimental effect of the Series 2 Prostaglandins, preventing them from being made in the body. As a result the platelets are less sticky, blood pressure is lower because the muscles in the walls of our arteries remain relaxed, loss of sodium and water by the kidneys takes place more effectively, inflammation response is decreased, and immune function is efficient.

It is now known that the ratios of these dietary fatty acids are very important. Consumption of linoleic acid leads to production of the enhanced fatty acid, arachidonic acid (20:4n-6). Prostaglandins based on arachidonic acid exacerbate stress and inflammatory states, and suppress immunoprotective functions (i.e. resistance to disease). Too much linolenic acid and other omega-3s may cause excessive bleeding during injury, surgery, or childbirth. Large amounts of any of these unsaturated fatty acids in the diet without a compensatory increase in antioxidant nutrients (especially Vitamin E), can speed oxidative damage to tissues, resulting in accelerated aging while increasing the risk of degenerative diseases.

Yet, a balanced ratio of both omega-3 and omega-6 fatty acids in the diet offers very positive health benefits. When omega-3 fatty acids predominate, the body will produce less arachidonic acid (20:4n-6). Immunity improves and inflammation subsides.

Essential Fats

Unfortunately, our Western diet has been almost devoid of omega-3 fatty acids. Creating the optimum intake of omega 3-to-omega 6 unsaturated fatty acids has become, therefore, an issue of prime importance for anyone concerned with health. We need to evaluate carefully the amounts of linoleic acid (n-6) we consume relative to our intake of alpha-linolenic acid (18:3n-3) and fish oils (EPA:20:5n-3 and DHA:22:6n-3).


The diagram in Figure 3 shows details of the omega-6 and omega-3 pathways. Pathway specifics indicate key eicosanoids (series 1 prostaglandins, series 2 prostaglandins, and series 3 prostaglandins), oil sources, and important nutrient cofactors that are needed for the reactions to take place.

essential fatty acids

Figure 3 – Essential Fatty Acids – pathways in the body

The information is this diagram gives the clues we need in order to provide optimal types and amounts of omega-6 and omega-3. For example, I have chosen for my essential fatty acid product cold pressed borage oil as the best natural source of gamma linoleic acid (GLA). It contains 20% by weight — the highest amount found in natural oils.


Work by Chapkin et. al. (see references 1–4 below) has identified the potent synergistic relationship between GLA, an omega-6 fatty acid, and the well-known omega-3 fatty acids. Chapkin has shown that, rather than simply the quantity of dietary omega-3s, it is the ratio of omega-6 to omega-3 fatty acids that is important in achieving full cardiovascular health and inflammatory control.

Furthermore, Chapkin has identified the ideal ratio. His published work deals with the importance of mixed diets supplying both linoleic and linolenic acids. To underscore the importance of these two fatty acids, refined oil supplements rich in enhanced forms were used. “Enhanced forms” are fatty acids derived from the original. They are one or more steps closer to the actual eicosanoid. In the human body, alpha linolenic acid (18:3n-3) is eventually converted to eicosapentaenoic acid (EPA, 20:5n-3) and linoleic acid (18:2n-6) is converted to gamma-linolenic (GLA, 18:3n-6) as its first enhanced form. Both enhanced fatty acids are precursors to eicosanoids.

In Chapkin’s research, superior health benefits were delivered by the mixed diet that supplied the eicosanoid precursors in a specific ratio. The balanced ratio of enhanced Omega-6 (GLA)-to-Omega-3 (EPA) fatty acids was 1:4.


Based upon the science discussed above, I developed a product with the correct Omega-6 (GLA)-to-Omega-3 (EPA) ratio and with proper amounts. It is available to you as Hank & Brians Essential Fats Plus E from Health Products Distributors, Inc. (HPDI).

Essential Fats Plus E


  1. UNIQUE COMBINATION — Essential Fats (EPA, DHA, GLA) plus Vitamin E. This unique formula offers more than one type of Vitamin E (not just d-alpha-tocopherol) and balanced essential fats.
  2. BALANCED ESSENTIAL FATS— Many EFA supplements contain only omega-3s, but for optimal function the body requires a balance of omega-3 and omega-6 essential fats. In addition, our special formula provides a 4-to-1 ratio of EPA to GLA in order to achieve a balance you need for optimal health.
  3. FULL-SPECTRUM VITAMIN E — Tocotrienols and tocopherols in this formula are natural vitamin E substances derived from oryza rice bran oil and protect polyunsatured EFAs against free-radical damage both in the capsule and in your body. Many Vitamin E supplements contain only d-alpha tocopherol, which is only a single component of the full-spectrum Vitamin E in this formula.
  4. ULTRAPURE — Molecularly distilled oils of extremely high-purity containing no PCBs, heavy metals, or oxidized contaminants. Free of excipients, additives, and common food allergens!

COMPOSITION: Six softgel capsules provides the following percentages of the Daily Value.

EPA (Eicosapentaenoic Acid 20:5 omega 3)
(from 2,000 mg of purified fish oils)
360 mg *
DHA (docosahexaenoic Acid 22:6 omega 3)
(from 2,000 mg of purified fish oils)
240 mg *
GLA (Gamma Linolenic Acid 18:3 omega 6)
(from 450 mg of cold pressed borage seed oil)
90 mg *
Vitamin E (d-alpha-tocopherol) (from 180 mg of Oryza rice bran oil) 24 IU 81%
Mixed Tocotrienols (d-gamma, d-alpha, and d-delta)
(from 180 mg of Oryza rice bran oil)
28.8 mg *

* No established Daily Value
† Daily Values based on a 2,000 calorie diet


Below we provide some of the functions and benefits obtained when by diet or supplementation the correct ratios and amounts of essential fatty acids are consumed.

• Regulate steroid production and hormone synthesis
• Regulate pressure in the eyes, joints, and blood vessels
• Regulate response to pain, inflammation, and swelling
• Mediate Immune Response
• Regulate bodily secretions and their viscosity
• Dilate or constrict blood vessels
• Regulate smooth muscle and autonomic reflexes
• Are primary constituents of cellular membranes
• Regulate the rate at which cells divide
• Necessary for the transport of oxygen from the red blood cells to tissues
• Necessary for proper kidney function and fluid balance
• Prevent red blood cells from clumping together
• Regulate nerve transmission


Please note that genetic testing for a wide range of genes and the enzymes they produce has indicated that essential fatty acids can be an important factor in helping the body overcome a variety negative gene variations. These negative gene variations include genes that relate to: 1) Inflammatory Response, 2) Exercise Performance, 3) Exercise Recovery, 4) Cardiovascular Fitness, 5) Body Composition, and 6) VO2 Max, Aerobic Capacity.

We will discuss this more deeply in a future blog article.


The body is best protected from a range of health issues when we supply a mixed diet of both omega-3 and omega-6 essential fatty acids. Studies show that we do not need to consume large amounts of fatty acids if the ratio is correct. These findings indicate that, for a typical human body, amounts of 90 mg GLA (18:3n-6) to 360 mg EPA (20:5n-3) taken daily will provide for the optimum production of the three major prostaglandins. These amounts are found in Hank & Brians Essential Fats Plus E.


The following includes abstracts of Chapkin’s published research on essential fatty acids.


Chapkin RS Somers SD Erickson KL

Dietary manipulation of macrophage phospholipid classes: selective increase of dihomogammalinolenic acid.

In: Lipids (1988 Aug) 23(8):766-70

Because alterations in the dietary content of fatty acids are an important method for modulating macrophage eicosanoid production, we have quantitated the levels of n-6 and n-3 polyunsaturated fatty acids in peritoneal macrophage individual phospholipids from mice fed diets (3 wk) with either safflower oil (SAF), predominantly containing 18:2n-6, borage, (BOR) containing 18:2n-6 and 18:3n-6, fish (MFO) containing 20:5n-3 and 22:6n-3, and borage/fish mixture (MIX) containing 18:2n-6, 18:3n-6, 20:5n-3 and 22:6n-3. Dietary n-3 fatty acids were readily incorporated into macrophage phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI). The increase in n-3 fatty acid levels was accompanied by a decrease in the absolute levels of 18:2n-6, 20:4n-6 and 22:4n-6 in PC, PE and PS. Interestingly, PI 20:4n-6 levels were not significantly lowered (P greater than 0.05) in MIX and MFO macrophages relative to SAF and BOR. These data demonstrate the unique ability of this phospholipid to selectively maintain its 20:4n-6 levels. In BOR and MIX animals, 20:3n-6 levels were significantly increased (P less than 0.05) in all phospholipids relative to SAF and MFO. The combination of borage and fish oils (MIX diet) produced the highest 20:3n-6/20:4n-6 ratio in all phospholipids. These data show that the macrophage eicosanoid precursor levels of 20:3n-6, 20:4n-6 and n-3 acids can be selectively manipulated through the use of specific dietary regimens. This is noteworthy because an increase in phospholipid levels of 20:3n-6 and 20:5n-3, while concomitantly reducing 20:4n-6, may have therapeutic potential in treating inflammatory disorders.

Institutional address: Department of Human Anatomy School of Medicine University of California Davis 95616.



Chapkin RS Carmichael SL

Effects of dietary n-3 and n-6 polyunsaturated fatty acids on macrophage phospholipid classes and subclasses.

In: Lipids (1990 Dec) 25(12):827-34

This study examined the effects of n-3 and n-6 polyunsaturated fatty acid alimentation on murine peritoneal macrophage phospholipids. Mice were fed complete diets supplemented with either corn oil predominantly containing 18:2n-6, borage oil containing 18:2n-6 and 18:3n-6, fish/corn oil mixture containing 18:2n-6, 20:5n-3 and 22:6n-3, or fish/borage oil mixture containing 18:2n-6, 18:3n-6, 20:5n-3 and 22:6n-3. After two weeks, the fatty acid levels of glycerophosphoserines (GPS), glycerophosphoinositols (GPI), sphingomyelin (SPH), and of the glycerophosphocholine (GPC) and glycerophosphoethanolamine (GPE) phospholipid subclasses were determined. We found that mouse peritoneal macrophage GPC contain primarily 1-O-alkyl-2-acyl (range for the dietary groups, 24.6-30.5 mol %) and 1,2-diacyl (63.2-67.2 mol %), and that GPE contains 1-O- alk-1′-enyl-2-acyl (40.9-47.4 mol %) and 1,2-diacyl (44.2-51.2 mol %) subclasses. In general, fish oil feeding increased macrophage 20:5n-3, 22:5n-3 and 22:6n-3 levels while simultaneously reducing 20:4n-6 in GPS, GPI, GPE and GPC subclasses except for 1-O-alk-1′-enyl-2-acyl GPC. Administration of 18:3n-6 rich diets (borage and fish/borage mixture) resulted in the accumulation of 20:3n-6 (2-carbon elongation product of 18:3n-6) in most phospholipids. In general, the novel combination of dietary 18:3n-6 and n-3 PUFA produced the highest 20:3n-6/20:4n-6 phospholipid fatty acid ratios. This study demonstrates that marked differences in the responses of macrophage phospholipid classes and subclasses exist following dietary manipulation.



Fan YY Chapkin RS

Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid.

In: J Nutr (1992 Aug) 122(8):1600-6

The ability of dietary gamma-linolenic acid [18:3(n-6)] to modulate prostaglandin biosynthesis in mouse resident peritoneal macrophages was determined. Mice were fed diets containing corn oil, borage oil or evening primrose oil or a mixture of borage and fish oils. After 2 wk, resident peritoneal macrophages were isolated and stimulated with unopsonized zymosan to induce prostaglandin synthesis. Borage oil, primrose oil and fish-borage oil mixture dietary groups (containing 25.6, 11.9 and 19.5 g gamma-linolenic acid/100 g fatty acids, respectively) had significantly (P less than 0.05) enhanced prostaglandin E1 synthesis (39.7, 29.4 and 73.0 nmol prostaglandin E1/mg protein, respectively) compared with corn oil-fed (containing less than 0.1 g gamma-linolenic acid/100 g fatty acids) animals, which synthesized less than 0.1 nmol prostaglandin E1/mg protein. Borage oil- and fish-borage oil mixture-fed mice had the highest biosynthetic ratio of prostaglandin E1/prostaglandin E2 (E1/E2 approximately 0.2). Macrophages from borage oil-fed mice synthesized the lowest amount of prostacyclin (198.7 nmol 6-keto-prostaglandin F1 alpha/mg protein) compared with corn oil-, primrose oil- and fish- borage oil mixture-fed mice (379.7, 764.8 and 384.2 nmol 6-keto- prostaglandin F1 alpha/mg protein, respectively). In addition, borage oil-, primrose oil- and fish-borage oil mixture-fed mice had significantly (P less than 0.05) higher levels of dihomo-gamma- linolenic acid [20:3(n-6)] in membrane phospholipids (5.5, 3.5 and 5.7 mol/100 mol, respectively) relative to corn oil-fed mice (2.0 mol/100 mol).



Fan YY Chapkin RS Ramos KS

Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro.

In: J Nutr (1996 Sep) 126(9):2083-8

This study was conducted to compare the impact of dietary lipids on the ability of macrophages to modulate vascular smooth muscle cell (SMC) DNA synthesis in vitro. C57BL/6 female mice were fed six different diets (6 mice/diet) containing 10% fat from corn oil (CO), borage oil (BO), primrose oil (PO), fish-corn oil mix (FC, 9:1, w/w), fish-borage oil mix (FB, 1:3, w/w), or fish-primrose oil mix (FP, 1:3, w/w) for 2 wk. Peritoneal macrophages were isolated from these mice, stimulated with zymosan or vehicle, and subsequently co-cultured with naive mouse aortic SMC in the presence of 3H-thymidine to measure SMC DNA synthesis. In this co-culture system, macrophages were seeded on 25-mm culture inserts (upper chamber) and SMC were seeded on 35-mm culture dishes (lower chamber). The two cell types were separated by a semipermeable membrane with a 30-kD cut-off. When quiescent SMC were co-cultured with macrophages, only the PO and FP diet groups had significantly (P < 0.05) lower SMC DNA synthesis compared with the control CO group whose diet contained no gamma- linolenic acid (GLA) or (n-3) polyunsaturated fatty acids (PUFA). In contrast, when cycling SMC were co-cultured with diet-modulated macrophages, all dietary groups except for those fed FC had significantly lower (P < 0.05) SMC DNA synthesis relative to the CO group. Although the level of GLA in PO and BO diets was different (11.5 and 22.3 g/100 g fatty acids, respectively), these treatments exerted comparable inhibitory effects on SMC DNA synthesis. The FP treatment consistently exhibited the lowest SMC DNA synthetic profile among the six dietary groups irrespective of SMC growth conditions. These data suggest that BO and PO alone or in combination with fish oil influence macrophage/smooth muscle cell interactions in a manner consistent with favorable modulation of the atherogenic process.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.


  1. Enig, Mary G. Know Your Fats: The Complete Primer for Understanding the Nutrition of Fats, Oils, and Cholesterol. Bethesda Press, 2000.


Fred Liers PhD Orthomolecular News Service No deaths from supplements vitaminsEvery year, HPDI publishes several articles from the Orthomolecular New Service (OMNS). This month we share a news release from OMNS about the fact in 2015 there were no deaths caused by nutritional supplements, including vitamins, minerals, amino acids, homeopathics, or herbs.


Orthomolecular Medicine News Service, January 3, 2017


by Andrew W. Saul, Editor

(OMNS, Jan 3, 2017) There were no deaths whatsoever from vitamins in the year 2015. The 33rd annual report from the American Association of Poison Control Centers shows zero deaths from multiple vitamins. And, there were no deaths whatsoever from vitamin A, niacin, pyridoxine (B-6) any other B-vitamin. There were no deaths from vitamin C, vitamin D, vitamin E, or from any vitamin at all.

no deaths supplements vitamins

Safe to consume: no deaths from nutritional supplements in 2015.

Not only are there no deaths from vitamins, there are also zero deaths from any supplement. The most recent (2015) information collected by the U.S. National Poison Data System, and published in the journal Clinical Toxicology (1), shows no deaths whatsoever from dietary supplements.


Zero deaths from vitamins. Want to bet this will never be on the evening news? Well, have you seen it there? And why not?

After all, over half of the U.S. population takes daily nutritional supplements. If each of those people took only one single tablet daily, that makes some 170,000,000 individual doses per day, for a total of well over 60 billion doses annually. Since many persons take far more than just one single vitamin tablet, actual consumption is considerably higher, and the safety of vitamin supplements is all the more remarkable.

It was claimed that one person died from vitamin supplements in the year 2015, according to AAPCC’s interpretation of information collected by the U.S. National Poison Data System. That single alleged “death” was supposedly due to “Other B-Vitamins.” This was claimed back in 2012 as well, with no substantiation then, either. Indeed, the AAPCC report specifically indicates no deaths from niacin (B-3) or pyridoxine (B-6). That therefore leaves folic acid, thiamine (B-1), riboflavin (B-2), biotin, pantothenic acid, and cobalamin (B-12) as the remaining B-vitamins that could be implicated. However, the safety record of these vitamins is extraordinarily good; no fatalities have ever been confirmed for any of them.

Abram Hoffer, MD, PhD, repeatedly said: “No one dies from vitamins.” He was right when he said it and he is still right today. The Orthomolecular Medicine News Service invites submission of specific scientific evidence conclusively demonstrating death caused by a vitamin.


There were zero deaths from any dietary mineral supplement. This means there were no fatalities from calcium, magnesium, chromium, zinc, colloidal silver, selenium, iron, or multimineral supplements. Reported in the “Electrolyte and Mineral” category was a fatality from the medical use of “Sodium and sodium salts” and another fatality from non-supplemental iron, which was clearly and specifically excluded from the supplement category.


Additionally, there were zero deaths from any amino acid or herbal product. This means no deaths at all from blue cohosh, echinacea, ginkgo biloba, ginseng, kava kava, St. John’s wort, valerian, yohimbe, Asian medicines, ayurvedic medicines, or any other botanical. There were zero deaths from creatine, blue-green algae, glucosamine, chondroitin, or melatonin. There were zero deaths from any homeopathic remedy.


There actually was one fatality alleged from some “Unknown Dietary Supplement or Homeopathic Agent.” This is hearsay at best, and scaremongering at worst. How can an accusation be based on the unknown? Claiming causation without even knowing what substance or ingredient to accuse is baseless.


If nutritional supplements are allegedly so “dangerous,” as the FDA, the news media, and even some physicians still claim, then where are the bodies? There aren’t any.


Mowry JB, Spyker DA, Brooks DE et al. 2015 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 33rd Annual Report. Clinical Toxicology 2016, 54:10, 924-1109, http://dx.doi.org/10.1080/15563650.2016.1245421

Data for vitamins, minerals, herbs, amino acids, and other supplements are presented in Table 22-B.

The complete 187-page article is available for free download from https://aapcc.s3.amazonaws.com/pdfs/annual_reports/2015_AAPCC_NPDS_Annual_Report_33rd_PDF.pdfor download this and all previous AAPCC Annual Reports at http://www.aapcc.org/annual-reports/

Nutritional Medicine is Orthomolecular Medicine

Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

Find a Doctor

To locate an orthomolecular physician near you: http://orthomolecular.org/resources/omns/v06n09.shtml

The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.

Editorial Review Board:

Ian Brighthope, M.D. (Australia)
Ralph K. Campbell, M.D. (USA)
Carolyn Dean, M.D., N.D. (USA)
Damien Downing, M.D. (United Kingdom)
Michael Ellis, M.D. (Australia)
Martin P. Gallagher, M.D., D.C. (USA)
Michael J. Gonzalez, N.M.D., D.Sc., Ph.D. (Puerto Rico)
William B. Grant, Ph.D. (USA)
Tonya S. Heyman, M.D. (USA)
Suzanne Humphries, M.D. (USA)
Ron Hunninghake, M.D. (USA)
Michael Janson, M.D. (USA)
Robert E. Jenkins, D.C. (USA)
Bo H. Jonsson, M.D., Ph.D. (Sweden)
Jeffrey J. Kotulski, D.O. (USA)
Peter H. Lauda, M.D. (Austria)
Thomas Levy, M.D., J.D. (USA)
Stuart Lindsey, Pharm.D. (USA)
Victor A. Marcial-Vega, M.D. (Puerto Rico)
Dave McCarthy, M.D. (USA)
Joseph Mercola, D.O. (USA)
Jorge R. Miranda-Massari, Pharm.D. (Puerto Rico)
Karin Munsterhjelm-Ahumada, M.D. (Finland)
W. Todd Penberthy, Ph.D. (USA)
Jeffrey A. Ruterbusch, D.O. (USA)
Gert E. Schuitemaker, Ph.D. (Netherlands)
Thomas L. Taxman, M.D. (USA)
Jagan Nathan Vamanan, M.D. (India)
Ken Walker, M.D. (Canada)
Atsuo Yanagisawa, M.D., Ph.D. (Japan)

Andrew W. Saul, Ph.D. (USA), Editor-In-Chief
Robert G. Smith, Ph.D. (USA), Assistant Editor
Helen Saul Case, M.S. (USA), Assistant Editor
Michael S. Stewart, B.Sc.C.S. (USA), Technology Editor
Jason M. Saul, JD (USA), Legal Consultant

Comments and media contact: drsaul@doctoryourself.com OMNS welcomes but is unable to respond to individual reader emails. Reader comments become the property of OMNS and may or may not be used for publication.

To Subscribe to the Orthomolecular News Service (OMNS) free: http://www.orthomolecular.org/subscribe.html

OMNS Archive: http://orthomolecular.org/resources/omns/index.shtml



Fred Liers PhD foundational supplements nutritionHPDI foundational supplements are designed to provide a complete range of essential nutrients that complement a healthy diet and lifestyle. They help ensure sufficient levels of nutrients required for good health.

We define foundational supplements as basic or “core” supplements that should be part of everyone’s daily regimen. They are the foundation of a complete nutritional supplement program.

HPDI has a three-tiered system of nutritional supplements: 1) Foundational Supplements, 2) Enhancement Formulas, and 3) Specific-Condition Formulas. All three tiers comprise a complete nutritional supplement program.

When properly combined, these three tiers of nutritional supplements help create optimal health. This month, I explain how to use HPDI foundational supplements, the base or bottom tier of the system (see cone diagram below).

The HPDI supplement system can be visualized as a cone having a base of Foundational Supplements ascending toward an apex of Enhancement Formulas and Specific Condition Formulas.

foundational supplements HPDI system

The HPDI Supplement System includes six types of Foundational Supplements forming its base.


My intent is to guide consumers and health care professionals to decide the foundational supplements that are best for their purposes, and that provide the most effective results.

For anyone new to HPDI’s Foundational Supplements system, we recommend six basic types of supplements. The six categories are: 1) multivitamin formulas, 2) vitamin C / antioxidant formulas, 3) essential fats, 4) high-RNA foods (Rejuvenate! superfoods), 5) gut health formulas, and 6) hydrogen formulas.

We established the original three types of foundational supplements about 1988. We have always suggested that clients and health professionals take and/or recommend multivitamins, vitamin C and antioxidants, and essential fats.

About 10 years ago, we added high-RNA foods (like Rejuvenate! superfoods) as a fourth type of foundational supplement because research indicates dietary nucleic acids are essential nutrients—see our blog articles on nucleic acids, Benjamin S. Frank, MD, PhD, and about Rejuvenate! superfoods (Original, Plus, and Berries & Herbs).

Two categories of foundational supplements are new: gut health formulas and hydrogen formulas. Hank wrote an article (Amending the HPDI Foundational Program) about these changes in April. We added these two categories after much consideration regarding their benefits, and have written extensively about them in this blog (see resources section below).

The entire HPDI supplement system is depicted (above) as a cone. The six types of foundational supplements form the base of the cone. Enhancement Formulas and Specific-Condition formulas sit above toward the apex.

ultimate protector foundational supplements

Ultimate Protector Nrf2 formula is a foundational supplement in the vitamin C / antioxidant category.


I use all six types of HPDI foundational supplements. I take the following supplements (below) and present them here as an example of how they can be integrated into a complete supplement regimen. Foundational Supplements I take:

1. Multivitamin: Hank & Brian’s Mighty Multi-Vite! (4 per day in divided doses)

2. Vitamin C / antioxidants: PRO-C (6-8 per day) and Ultimate Protector Nrf2 activator (8-12 per day)

3. Essential Fats: Essential Fats Plus E (4 per day)

4. Rejuvenate!™ superfood: All three Rejuvenate! superfoods (2-8 scoops per day)

5. Gut Health: RESTORE For Gut Health (1-2 ounces per day) and Prescript-Assist™ probiotic (soil-based organisms) (1-3 per week)

6. Hydrogen: Megahydrate (2-6 per day)

Taking one supplement from each of the six foundational supplement categories builds, supports, and maintains optimal health.

We at HPDI recommend everyone take one of each type of foundational supplement. That is, we suggest an individual select for personal use a multivitamin, vitamin C/antioxidant formula, essential fats formula, Rejuvenate!™ superfood (or other high-RNA superfood), hydrogen product, and at least one gut health product (depending on their gut-health needs).

Similarly we suggest health care professionals recommend for their clients one of each of the six types of foundational supplements.

The other two categories in the HPDI nutritional supplement system are Enhancement Formulas and Specific-Condition Formulas (see cone diagram). These are not foundational supplements. However, I include the supplements I take in these categories for the sake of completeness, as well as to show how Enhancement and Specific-Condition Formulas integrate with Foundational Supplements to form a complete supplement program providing a wide-range of essential nutrients required for health.

Enhancement Formulas I take include: B-Complex-50 (B complex), Myo-Mag (magnesium/malic acid), Ubiquinol-50, Bone Guardian, and Vitamin D3 Plus.

Specific Condition Formulas I take include: Joint Health Formula, Allergy Support Formula, Eye & Vision Formula, Intestinal Rejuvenation Formula, and Warrior Mist (pain topical), and Warrior Sleep (sleep topical).

While I take supplements from all three categories (Foundationals, Enhancements, and Specific-Condition) in the HPDI supplement system, I always prioritize foundational supplements—I take them first—because they are base on which my personal supplement program rests.

Foundational supplements should be the base on which your supplement program—or those of your clients—rests, as well.

We have seen the results of taking a complete set of foundational supplements. They work because the nutrients they provide are needed by everyone.

HPDI foundational supplements multivitamin

Muti Two Caps is a high-potency multi with coenzyme forms for optimal utilization in the body.


Individuals who take all types of foundational supplements do best in terms of optimizing health. The reason is that all six types provide nutrients required for good health.

I can attest that HPDI Foundational Supplements are effective for improving or maintaining good health. In addition, I have witnessed numerous instances where individuals benefit most greatly when taking all four–and now all six–types of foundational supplements.

Each of the six categories of foundational supplement provide unique benefits. Yet, each performs functions required by the human body for good health. That is one reason when they are combined they exert synergistic effects for health going far beyond the benefits of using, one, two, or three of the types of foundational supplements.


I talk to people who may or may not take a multivitamin. And they may or may not take vitamin C. Yet, they may take calcium for their bones, glucosamine for their joints, and lutein for their eyes. Or they may take a low-potency, off-the-shelf multivitamin providing merely the RDA for all nutrients.

There is nothing wrong with individuals taking supplements they regard as important or useful. But that cannot guarantee that a wide range—and sufficient levels—of nutrients necessary for health are available to the body on a regular basis.

In fact, I regard the supplement intake programs of most persons to be “hit-or-miss.” They may consume nutrients important for a few functions in the body, yet fail to obtain other essential nutrients required for the nutrients they take to work most effectively. We have written extensively on this topic on our website and in blog articles (see below).

Not taking regularly a complete set of foundational supplements likely means key nutrients (and key levels of nutrients) go missing. Over time, this means fewer and lower levels of nutrients available to support the body’s needs for them at levels known to sustain the good health.

The best way to ensure a sufficient range of nutrients at plentiful levels is to take foundational supplements. After a baseline of nutrients is established by taking foundational supplements, additional supplements can be added, as necessary.

rejuvenate superfood foundational supplements

High-RNA foods like Rejuvenate! PLUS superfood provide dietary nucleic acids important for health.


After obtaining sufficient levels of basic nutrients required for health, then a person can add (or you can recommend) specific nutrients or formulas that target certain problems or issues. This is the basis for HPDI development of Enhancement Formulas and Specific-Condition Formulas.

Nutritional supplements in the categories of Enhancement Formulas and Specific-Condition Formulas therefore “stack” on top of HPDI’s Foundational Supplements (see cone diagram above). In this way, a complete nutritional supplement program begins with the most essential nutrients and continues with customizations based on the unique needs of an individual.


Enhancement Formulas in the HPDI system are supplements we regard as falling into the next tier in terms of importance, at least for most people. They do not necessarily provide essential nutrients, and yet many people (including myself) benefit significantly from them.

Enhancement Formulas include: magnesium formulas (topical and capsule), Vitamin D3 Plus, Nascent Iodine, Vitamin B12 (methylcobalamin), mushroom-based products (like Immune-Assist™), Prolyt (proteolytic enzymes), Digase (plant-based enzymes), and Warrior Mist (topical pain reliever), and many other formulas.


In the HPDI system, individuals can add (in a modular way) various formulas and single nutrients designed to support a particular set of needs or a target a specific condition.

We offer a complete range of supplements (almost 100) including a range of supplements formulated to address specific conditions. These include Joint Health Formula, Eye & Vision Formula, Blood Sugar Support, Allergy Support Plus, Prosta Plus, and many other formulas.


HPDI Foundational Supplements collectively form the base tier of a complete nutritional supplement system comprised of three tiers: 1) Foundational Supplements (six types), 2) Enhancement Formulas (or simply “Enhancements”), and 3) Specific-Condition Formulas.

Foundational Supplements are necessary because they provide nutrients foundational to health. Taking them daily or recommending your clients take them daily can help mean big differences in health, nutrition, and quality of life.

We at HPDI design our nutritional supplements to be the most effective dietary supplements available. HPDI products are known for: 1) Advanced Formulation (including use of superior forms of nutrients), 2) Ultra-High Purity, 3) Avoidance of Harmful Ingredients, and 4) being made with Good Manufacturing Practices (GMP). For more details, please see The HPDI Difference and our Statement on Additives (Excipients).

At least 40 of HPDI’s products are formulated by Dr. Hank Liers. They fall in all categories in HPDI’s supplement system. They can be found under “Dr. Hank Liers original formulas.”

omega plus foundational supplement

Omega Plus provides exceptionally well-balanced omega-3 and omega-6 fatty acids.


We frequently get questions from HPDI clients and resellers regarding foundational supplements. These questions include:

“Why did you add gut health and hydrogen products to your foundational supplements program?”
We found it necessary to add categories for gut health and hydrogen because they provide nutrients that are support the body and help ensure the foundational supplement system supports health most effectively. You can read more in previous blog articles (see below).

“Which is the better multivitamin: Multi Two or Mighty Multi-Vite!™?”
It depends on whether you need more B vitamins or antioxidants. Multi Two provides more B vitamins and Mighty Multi-Vite™ provides more antioxidants and cofactors. I take a separate HPDI B-Complex-50 formula, so I take Mighty Multi-Vite!™ as my primary multivitamin.

“What are the differences between Rejuvenate!™ Original, PLUS, and Berries & Herbs superfoods?”
They each provide about 340 mg of dietary nucleic acids. Original is the “greenest” with a large percentage of dietary nucleic acids coming from chlorella and spirunlina. PLUS is our most popular and 30% is identical to Original with more protein and a built-in multivitamin complex. Berries & Herbs contains no greens, yet more nucleic acids (390 mg), protein, and a built-in multivitamin. See our Rejuvenate! comparison page for more information.

“Should I take a vitamin C formula with antioxidants like PRO-C or one with Nrf2 activators like Ultimate Protector?”
Both provide vitamin C and Nrf2 activators, but Ultimate Protector provides more types of Nrf2 activators. Ultimate Protector capsules are smaller than PRO-C capsules, so a daily dose may require taking more capsules.

“How important are hydrogen supplements?”
Very important for energy production, recovery, antioxidant functions, and gut health. Hydrogen supplements like Active H2 and Megahydrate ensure high levels of hydrogen are available in the body.

What are your best products for supporting gut health?
It depends on your needs: cleansing (Intestinal Rejuvenation Formula), probiotic/microbiome support (Prescript-Assist™), or tightening tight junctions in the gut (RESTORE)? We offer products for all these purposes.

These are just a few questions frequently asked about HPDI foundational supplements. If you need more information about products, please contact the HPDI office (800-228-4265) or email support@healthproductsdistributors.com.

You can also contact Fred Liers, PhD (520-400-0155) or Hank Liers, PhD (formulator) with questions you may have regarding products, ingredients, or formulation.


Foundational Supplements

HPDI Full Product Overview

The Need for Foundational Supplements (.pdf)

The HPDI Difference (4 Pillars of Formulation)


Amending the HPDI Foundational Supplements Program

Foundational Supplements Remain Fundamental

Vitamin C / Antioxidants

PRO-C and Ultimate Protector Comparison

Questions and Answers about Ultimate Protector

The Amazing Healing Potential of Natural Nrf2 Activators

Ultimate Protector™: First Impressions

Ultimate Protector™ Brunswick Labs ORAC5.0™ Test Results

Preventing Free-Radical Damage Using Ultimate Protector™

Description and Comparison of ORAC Tests for Well Known Plant Ingredients and Ultimate Protector™

Ultimate Protector and the Role of Foundational Supplements for Health

Natural Phytochemical Nrf2 Activators for Chemoprevention

New Directions for Preventing Free Radical Damage

Review of Scientific Research on Oligomeric Proanthocyanidins (OPC)” by Dr. Hank Liers

“Vitamin C – An Amazing Nutrient” by Dr. Hank Liers

Rejuvenate! Superfoods

Rejuvenate! Berries & Herbs: Ingredients for Optimal Nutrition

9 Things to Know About Rejuvenate!™ Superfoods

High-RNA Rejuvenate!™ Superfood

Get Results with Rejuvenate! Superfoods

Dietary RNA for Athletic Performance



Super-Tasty Morning Nutritional Drinks


The Science Behind Megahydrate

Hydrogen for Optimal Health

Wonders of Molecular Hydrogen

Gut Health

Gut Health – Effects of Glyphosate and Antibiotics

Gut Health – Intestinal Rejuvenation Formula


Vitamin formulas, including multivitamins

Mighty Multi-Vite!

Multi Two Caps

Rejuvenate!™ Berries & Herbs

Rejuvenate!™ PLUS

Rejuvenate!™ (Original)

Rejuvenate! Superfoods: Product Comparison

Ultimate Protector™ Nrf2 Activator (vitamin C/antioxidant)

PRO-C (Vitamin C/Antioxidant formula)

Intestinal Rejuvenation Formula (gut health)

Restore For Gut Health (lignite formula)

Active H2 (hydrogen)

Megahydrate (hydrogen)

Prescript-Assist™ (probiotic/prebiotic)