Soil based organisms (SBO) may be among the most important things for your health. No kidding.
Studies show SBOs confer a host of healthy benefits. While certain benefits provided by SBOs may overlap with those conferred by lactobacteria-based probiotics, it is apparent that soil based organisms offer significant advantages.
In fact, Fred wrote an article on probiotics last year covering a new type of probiotic and prebiotic formula that provides soil based organisms. Studies on the human microbiome are revealing many surprises that give us a new understanding of the importance of soil based organisms for human gut ecology.
Scientific research on the beneficial roles played by bacteria for human health is advancing rapidly. In 2012, Hank wrote short piece titled, “A New View of the Role of Bacteria in Health.” A key point he explains in that article is the fact that the our body’s microbiome contains 99 times more genetic material that is non-human (i.e., bacterial) than human!!
Another key point is that bacteria living on (and in) us possesses a sophisticated communication system enabling them to “talk” in both intraspecies and interspecies ways using a kind of hormone signaling language. Hank cites the 2009 TED talk of Princeton molecular biologist Dr. Bonnie Bassler who studies how bacteria communicate with each other through chemical signals that allow groups of bacteria to act as a unit, i.e., take collective action.
Dr. Bassler’s groundbreaking research holds promise as medical research, and supports the idea that probiotics, including soil based organisms (SBO) play essential roles in human health and wellness. In fact, the major implication of current discoveries regarding roles played by bacteria in the human microbiome is that beneficial bacteria are far more important for health than previously understood.
A practical application of new knowledge regarding the human microbiome may simply be the recognition that increased consumption of soil based organisms is good for us.
WHAT ARE SOIL BASED ORGANISMS (SBO)?
There are thousands of different types of bacteria found naturally in soils. These bacteria in soil and dirt historically performed many beneficial functions for us. It appears they help our bodies regulate immunity, and protect us from bacterial and fungal overgrowths in our intestinal tracts.
Up until 100 years ago (or less for some people), soil based organisms were an everyday part of the diet. Not that long ago, our country was comprised mostly of farmers. Agriculture was more about getting dirty than about efficient machinery and chemicals inputs (i.e., industrial agriculture). At that time, almost everyone would have consumed soil based organisms on vegetables and other foods from the fields, gardens, and orchards.
Nowadays due to lack of exposure to soil based organisms resulting from modern food processing systems and the extensive use of pesticides that destroy the organisms, the average person has a very different composition of intestinal flora from their ancestors. There are far fewer soil based organisms, and more lactic acid bacteria. In addition, the use of antibiotics for young children has further swayed the balance away from these beneficial bacteria.
With a dramatic rise in research into the benefits of soil based organisms, new products have been developed that help us reintroduce them into our intestinal tracts. There they offer many benefits, including improving digestion, boosting immunity, and supporting overall good health in the intestines (with such benefits as reduced bloating, flatulence, and constipation).
And for example, certain soil based organisms are known to secrete proteins activating the immune system, as well as stimulating the production of white blood cells and antibodies.
BENEFITS OF SOIL BASED ORGANISMS
Increasing evidence supports the idea that soil based organisms are essential for human health. Here are a few of the reported benefits:
• Improved Gastrointestinal Health
• Prevention of Gut Colonization by Harmful Bacteria and Fungi
• Support for Intestinal Regeneration
• Support for Balancing Gut Microbiota
• Help Balance Colon pH
• Increase Resistance to Harmful Bacteria and Fungi
• Increase Absorption of Nutrients in the Intestines
• Help Replenish Friendly Microflora in the Colon
• Support Overall Health and Well Being
• Enhance Metabolism in the Gut
• Promote and Normalize Bowel Function
• Help Reduce Gas and Bloating
• Improve Immune System Function
• Improve GI Tract Barrier Function
• Many Other Benefits
SOIL BASED ORGANISMS ARE DIFFERENT THAN LACTOBACTERIA
Most people today either take or are aware of the benefits of probiotics containing lactic acid-based bacteria. These include commonly known strains of lactobacilli and bifidobacteria. Lactic-acid bacteria certainly are beneficial. There is a large body of research showing their high value for supporting digestion, immunity, and many other benefits. But they do have certain limitations.
Many of the lactic acid bacteria in probiotic formulas have difficulty making it through the stomach’s acidic environment. Thus, the bacteria arrive in the small intestine in vastly reduced numbers compared to the amount that must be consumed. Nutritionists therefore usually recommend taking probiotics with a large number of “colony forming units” (CFU) in order to ensure viability of the bacteria.
In addition, the benefits conferred by taking lactic acid bacteria may depend upon continuing usage. That is, certain studies indicate the benefits of these bacteria are greatly reduced after usage ends.
Soil based organisms offer several advantages compared to lactic-acid bacteria. First, they are extremely hardy and better able to withstand the acidic environment in the stomach. They are in fact, “endospore-forming” bacteria that surround themselves in a hard exterior that travels more effectively through the intestinal tract.
This means soil based organisms are far more likely to arrive intact in the small intestines (where they need to be) than lactobacteria. It also means that products containing soil-based organisms can provide fewer colony forming units and still be effective. That is, probiotic supplements with soil based organisms are more efficient at getting CFUs into the small intestines. It also eliminates or reduces the need for special coatings, manufacturing processes, or “delivery systems” that must be created as a means to improve delivery rates of lactic acid bacteria.
Soil based organisms have also been shown to colonize the gut more effectively than lactic-acid bacteria. This may partially relate to the fact that they are hardier and make it to the small intestines in greater numbers. A major benefit is that this characteristic of SBOs may allow a reduction is dosage onto a “maintenance” level sooner without concerns that benefits of probiotic supplementation will disappear.
PRESCRIPT-ASSIST™ BROAD-SPECTRUM PROBIOTIC & PREBIOTIC
We at Health Products Distributors, Inc. researched various products containing soil based organisms. We now carry Prescript-Assist™, an effective, well-regarded broad spectrum probiotic and prebiotic formula.
Prescript-Assist™ provides 29 naturally resilient strains that support your body’s natural intestinal balance. Having so many strains means that this formula better reflects the great microbial diversity of the intestines versus typical probiotic products. In fact, more than 1,000 different species of microbes inhabit the human gut. Prescript-Assist™ includes Bacillus subtilis, which is a well-proven probiotic species found in traditional foods.
Below is a complete list of the strains of soil based organisms provided by Prescript-Assist. One 600 mg capsule of Prescript-Assist includes the following microorganisms (as well as the prebiotic Leonardite):
Arthrobacter agilis, Arthrobacter citreus, Arthrobacter globiformis, Arthrobacter luteus, Arthrobacter simplex, Acinetobacter calcoaceticus, Azotobacter chroococcum, Azotobacter paspali, Azospirillum brasiliense, Azospirillum lipoferum, Bacillus brevis, Bacillus marcerans, Bacillus pumilus, Bacillus polymyxa, Bacillus subtilis, Bacteroides lipolyticum, Bacteriodes succinogenes, Brevibacterium lipolyticum, Brevibacterium stationis, Kurthia zopfii, Myrothecium verrucaria, Pseudomonas calcis, Pseudomonas dentrificans, Pseudomonas fluorescens, Pseudomonas glathei, Phanerochaete chrysosporium, Streptomyces fradiae, Streptomyces cellulosae, Streptomyces griseoflavus.
It is clear that the number and types of species found in the gastrointestinal (GI) tract can be a primary difference between an optimal digestive system and immune system, and one less than optimally functional. In scientific studies, individuals exhibiting higher levels of gastrointestinal distress and gut irregularities have been found to have a correspondingly lower variety of beneficial bacteria in the intestines.
Prescript-Assist™ is a clinically proven probiotic supplement designed to ensure maximum viability of the many organisms it provides. The formula offers inherent viability because the species it provides are naturally adapted for survival in the human gastrointestinal tract. That is, these 29 species are environmentally based (SBO) species drawn from the terrestrial microbiome where they have prospered and adapted for millenia to beneficially coexist with humans.
Unlike conventional Lactobacillus and Bifidobacterium probiotics, the strains in Prescript-Assist are a balanced formulation of a new generation of probiotics, capable of forming a protective shield until reaching the probiotic-friendly environment of the intestines. These organisms are resistant to acid, bile, and heat. In fact, routine testing of Prescript-Assist confirms it has a 95% viability two years after date of manufacture.
The inherent viability of the soil based organisms in Prescript-Assist means there are no requirements for nano-encapsulation or hard-shelled enteric-coated capsules, which both are essentially attempts to force viability of probiotic species rather than utilizing hardy strains naturally preadapted to our bodies.
Typical probiotic formulas therefore contain the relatively low-viability lactic acid bacteria that must be protected by technologies (e.g., microencapsulation) due to their inherent fragility. These fragile bacteria have a difficult time surviving because they are readily destroyed within the acidic environment of the stomach. Although patented enteric coatings can help survival rates, the provision of high-viabiltiy organisms that reach the intestines intact due to the inherent strength of their natural spore structure makes more sense as a means to protect against degradation in the stomach and intestinal tract.
In sum, Prescript-Assist™ provides bacteria that reach the intestines intact due to the fact that the spore structure protects against degradation or destruction by stomach acids.
29 SYMBIOTIC SPECIES FOUND IN ORGANIC, FERTILE SOILS
Science has shown that a baby’s exposure to maternal bacterial cultures during natural birth help it to form a healthy, disease-resistant bacterial defense. Likewise, the environmental and soil-based bacteria commonly found in foods grown in fertile organic soils assist in growing and maintaining a healthy makeup of internal flora in humans.
This is the basis of SBO (soil based organism) probiotics like Prescript-Assist.™ SBO probiotics have risen in recognition recently as clinical evidence grows to support their effectiveness. Species from the Bacillus genus, a gut-adapted spore-forming bacteria found in Prescript-Assist, have been demonstrated safe and effective in in vitro and in vivo studies (see Resources section below).
Dr. Mehmet Oz of the Dr. Oz Show says, “Spore form probiotics are the Chuck Norris of probiotics: total tough guys. They have to be to survive splashing around in your stomach’s acid bath. Wimpier types—including live cultures in yogurt—often throw in the towel.”
Among brands of SBO probiotics, Prescript-Assist offers the greatest diversity of species. It is the diversity and the resilience of the Prescript-Assist formulation that accounts for its proven success in peer-reviewed, published clinical trials.
BROAD SPECTRUM DIVERSITY
The Human Microbiome Project (NIH-funded five-years research study by a consortium of nearly 80 universities and institutions) confirmed that the number of microbial species found in the human intestines numbers in the thousands rather than hundreds.
Just as importantly, the project results showed that the distribution of a variety of strains capable of performing similar tasks is more important than the individual species themselves. This information underscores the importance of broad spectrum diversity, and therefore the role that can be played by multi-strain probiotic complexes, such as Prescript-Assist.
A review article in Cell refers to the gut as a “natural laboratory for studying the ‘microevolution’ of humans.” The authors write: “In this view, we are seen as superorganisms composed of an amalgam of both microbial and H. sapiens cells, where the survival of microbe and human is interdependent.”
With its balanced formulation of 29 beneficial strains selected to mimic the natural flora found in traditional and paleolithic diets, Prescript-Assist is the only professional-grade probiotic to contain 29 species, 12 different genera, and all four of the most common phyla found in the human digestive tract, including Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria.
ADDITIONAL ADVANTAGES OF PRESCRIPT-ASSIST™ PROBIOTIC FORMULA
SHELF STABILITY (NO REFRIGERATION NEEDED)
Prescript-Assist offers exceptional shelf stability. It is well known that conventional probiotics (i.e., lactic acid bacteria) are readily damaged, degraded, and destroyed by heat and pressure during the manufacturing process. They are also degraded by exposure to light and by temperature changes. Because they lack shelf stability, if they are not kept refrigerated, they often cannot provide a sufficient quantity of organisms by the time of ingestion.
In contrast, Prescript-Assist features probiotic bacteria protected by a durable seed-like structure, so that they are better safeguarded against environmental factors, including heat, pressure, light, or temperature variability. Indeed, testing confirms that the probiotic bacteria in Prescript-Assist remain 95% viable two years after their date of manufacture without any need for refrigeration.
PREBIOTIC SUPPORT – LEONARDITE (FULVIC & HUMIC ACIDS)
Most probiotic formulas do not contain any prebiotics, which are a food source for bacteria, and help accelerate their growth. Prescript-Assist uniquely contains Leonardite, which is a prebiotic mixture of humic and fulvic acids, which allows the beneficial bacteria to proliferate and thrive.
Fulvic and humic acids belong to a group of organic substances called humic substances. These are dark brown constituents of humus found in soil that contribute to the character of soil, and are precursors to fossil fuels. They are also found in peat, coal upland streams, dystrophic lakes, and ocean water. Both humic acid and fulvic acid are excellent chelators and powerful antioxidants.
Humic acid is normally found in the form of “humate” (the salt of humic acid), i.e., humic acid bound to a nutritional mineral element. Fulvic acid is normally found in the form of ‘fulvate’ (the salt of fulvic acid), i.e., fulvic acid bound to a nutritional mineral element.
A substantial fraction of the mass of the humic acids is in carboxylic acid functional groups, which endow these molecules with the ability to chelate (bind) positively charged multivalent ions (Mg2+, Ca2+, Fe2+, Fe3+, most other “trace elements” of value to plants, as well as other ions that have no positive biological role, such as Cd2+ and Pb2+).
This chelation of ions is probably the most important role of humic acids with respect to living systems. By chelating the ions, they facilitate the uptake of these ions by several mechanisms, one of which is preventing their precipitation, another appears to be a direct and positive influence on their bioavailability.
Humic acid and fulvic acid have been the subject of many years of scientific study not only because of their role in soil and plant biology, but also with respect to their chelation capabilities. That is, for their proven capacities in removing heavy metals from the human body.
Humic and fulvic acids bind only with double valency positive cations, i.e., nutritional elements and/or heavy metal ions. It is likely that a heavy metal ion will displace a lighter, nutritional metal ion and bind with the humate or fulvate.
Many health care practitioners recommend fulvic acid as an electrolyte (to increase cellular electrical efficiency) and supplement to take in combination with trace mineral supplements in order to assist in their uptake by the body. Fulvic acid bonds with these minerals. Because it is a small molecule and therefore easily able to pass through cell membranes, it allows delivery of the minerals efficiently into cells.
Most products are based on processed humate, taken from high quality soil sources, containing large amounts of nutritional cations already bound into the matrix. They are therefore not likely to deplete an individual’s mineral levels. As fulvic acid/fulvate is the smaller molecule, it is more easily absorbed into the cells. It is regarded as an excellent method of delivery for trace elements and nutrients into the body, as well as being an excellent chelator.
Observed Effects of Humic Acids on Animals
Our focus in this article is upon the effects of soil based organisms and prebiotics (e.g., humic and fulvic acids) in humans. However, it is worth noting that various animal studies show a large number of benefits. These studies show the following benefits:
Covering mucous membrane and adstringent effects
Humic acids can form a protective film on the mucuous epithelium of the gastrointestinal tract against infections and toxins. The macrocolloidal structure of humic acids ensures a good shielding on the mucous membrane of the stomach and gut, the peripheral capillaries, and damaged mucosal cells. As a result of this process, the resorption of toxic metabolites is reduced or fully prevented, especially after infections, in case of residues of harmful substances in foods. Furthermore, humic acids help to prevent excessive loss of water via the intestine.
Antibacterial and virucidal effects
Humic acids can influence the metabolism of proteins and carbonhydrates of microbes by catalytic means. This leads to a directly damaging effect against bacteria or viruses. A second mechanism is related to the interionic bonds of high-molecular protein fractions (toxins) of infectious microbes. Their toxic impact on physiological processes of mucous membrane cells can be weakened considerably or even completely blocked.
Dermal, oral, or subcutaneous application of humic acids leads to inhibitory effects on inflammation. The ability to inhibit inflammation is considered to be related with the flavonoid groups contained in humic acids.
Antiresorptive and adsorptive effects
As high-molecular humic acids remain in the gastrointestinal tract almost entirely following the enteral application (there is no self-resorption), antiresorptive and adsorptive effects take place where they are needed—in the digestive tract. Primarily cationoid noxes (protein toxins, toxic substances) are fixed, their resorption is reduced considerably or even prevented completely and their elimination through the bowel is promoted. As adsorption by humic acids includes not only physical and chemical reactions, but also complex-formation and ion-exchange, it is more intensive and dynamic compared to purely physical adsorbents.
Effects on the immune system
Humic acids stimulate the resistance forces of the body and lead to an increase in the phagocytosis activity. The inducer effect of phenolic components (groups) of humic acids is believed to be responsible for the immunological effects and is the basis for the success of the treatment of the so-called “factor” diseases in young animals.
Humic acids stabilize the intestinal flora, thereby ensuring improved utilization of nutrients in foods. This leads to an increase in liveweight of the animal without increasing the amount of feed given to the animal.
BACKED BY SCIENCE
Probiotic supplement formulas typically do not offer product-specific clinical studies validating their effectiveness. Prescript-Assist™ is different. It is supported by a peer-reviewed, placebo-controlled human clinical trial, and a one-year follow-up study that verifies its long-term efficacy.
Below is a summary of major features and benefits provided by Prescript-Assist™.
SUMMARY OF KEY BENEFITS
- No Need for Refrigeration.
- Backed by Sound Science: Supported by peer-reviewed, published clinical studies.
- Inherent Organism Viability: A matrix of superior, highly resilient microflora whose organic, seed-like structures survive the early GI tract to thrive in the intestines.
- Contains Bacillus subtilis: A proven probiotic species found in traditional foods.
- 29 Symbiotic Organisms: A balanced formulation specially selected to mimic the natural flora found in traditional and paleolithic diets.
- Proven Shelf Stable: With variations of less than 5% over two years from date of manufacture when stored at 98°F / 37°C
- Supported By Prebiotics. Includes Leonardite, a prebiotic mixture of humic and fulvic acids, which allows beneficial bacteria to proliferate and thrive.
- Gluten-Free, Dairy Free, and Vegan.
DIRECTIONS FOR USE
As a dietary supplement for adults, take 1–2 capsules per day, or as directed by your health care professional. May be taken with or without food.
No refrigeration necessary. Store under normal conditions.
Routine viability testing confirms greater than 95% viability two years after date of manufacture — without refrigeration. See individual package for expiration dates.
A VIABLE PROBIOTIC FORMULA WITH SOIL BASED ORGANISMS
We at HPDI always strive to bring our customers the best products and formulas available whether or not we ourselves design and produce them.
When the opportunity to carry Prescript-Assist™ arose, we were quick to recognize its many benefits and advantages. We offer this unique formula knowing that it is safe, effective, and can help improve the health of our customers and their patients.
We also know that Prescript-Assist can be used effectively in combination with our other supplements (i.e., HPDI foundational supplements and superfoods), including formulas we design specifically for GI health like Intestinal Rejuvenation Formula.
We ourselves take Prescript-Assist™ and experience major health benefits. In addition, we personally witness and hear from many individuals (including health care professionals) who have experienced the benefits of the formula. The results reported are excellent.
Today it is more important than ever to utilize our current (and rapidly expanding) knowledge about the human microbiome and its constituents to support optimal health and wellness. Science tells us that the human microbiome historically has been populated by a broad range of soil based organisms.
Where we have moved away from nature and traditional agriculture, individuals’ microbiomes can become less vibrant, diverse, and robust. Supplements like Prescript-Assist providing soil based organisms can help bring us closer to having the microbiome our ancestors enjoyed.
Learn more about Prescript-Assist™ Probiotic Formula.
Apply to become an HPDI wholesaler.
SOURCES AND RESOURCES
ARTICLES & INFORMATION
Prescript-Assist™ Broad Spectrum Probiotic & Prebiotic (from the HPDI blog)
The Safety of Bacillus subtilis and Bacillus indicus as Food Probiotics (J. Applied Microbiology)
The Safety of Two Bacillus Probiotic Strains for Human Use (Digestive Diseases and Sciences)
Prescript-Assist™ Probiotic Formula (HPDI website)
Intestinal Rejuvenation Formula (HPDI website)