Maintaining tight junctions is important because they protect your body from substances entering the blood stream. ION* GUT HEALTH (formerly Restore) also supports the communications systems of the bacteria in your microbiome.
Tight junctions are natural barriers protecting the lining of your gut barrier, organs such as kidneys and heart, and the blood-brain barrier thereby keeping out unwanted substances. Even as we take in nutrients from the GI tract, the function of tight junctions is maintaining the integrity of the gut wall and other barriers that protect the body.
These days, our gut membrane has a tough job keeping out unwanted substances. Because tight junctions are weakened by many things, including highly processed foods, especially those containing gluten and gliadin, the herbicide glyphosate (the primary ingredient in RoundUp weedkiller), and other exposures like electromagnetic fields (EMF) from digital devices and Wi-Fi networks.
As a result of weakened tight junctions, undesirable substances from food proteins, harmful chemicals and other toxins can slip though into our bloodstream. This can lead to a powerful immune response that can weaken immunity and cause significant inflammation. Foreign substances in the bloodstream can also result in extreme food allergies and food sensitivities to various toxins entering the body.
We live in an age in which our microbiome health is under assault. Studies show our ancient ancestors had 20,000–30,000 different strains of beneficial bacteria in their GI tracts. Many people today have just 5,000 or less. Why is that?
There are many reasons for low microbiome diversity. These reasons include antiobiotic use (both from pharmaceuticals and foods), glyphosate (which essentially acts like an antibiotic), processed foods (especially those containing gluten and gliadin), and systemic degradation of the gut environment rendering it less hospitable for maintaining health populations of gut flora.
These impacts are significant because diversity in your microbiome not only supports gut health, but also appropriate brain health, immune system health, and overall vitality. ION* Gut Health (Restore) acts as a “microbiome fertilizer” helping establish and maintain healthy microbiota.
In fact, ION* Gut Health (Restore) contains important “redox” molecules produced millions of years ago by existing soil bacteria. These molecules are an important part of communications systems within the body between gut bacteria and with the body’s mitochondria. These communication systems play an important role in establishing proper homeostasis throughout the body.
REASONS TO USE ION* GUT HEALTH (RESTORE)
There are important reasons to try ION* GUT HEALTH (Restore)—whether or not you experience significant gut health issues. These reasons include:
• Maintaining strong tight junctions for mega membrane health, and helping the body restore tight junction integrity
• Creating an environment in which beneficial bacteria can thrive
• Boosting microbiome diversity
• Healing the gut
• Mitigating the adverse effects substances like antibiotics, gluten/gliadin, glyphosate, and GMOs on microbiome health
• Supporting immune system function
• Protecting integrity of blood-brain barrier
Other benefits include support for respiratory wellness, enhancing mental clarity, and promoting proper homeostasis throughout the body.
For all these reasons and more, you should consider taking ION* GUT HEALTH (formerly Restore). You can start by taking one teaspoon or less daily, and gradually increasing your dose to one tablespoon or more.
I have taken ION* GUT HEALTH (formerly Restore) daily for more than two years, and benefit greatly from it. The most noticeable effects are a complete cessation of spring allergies (after two decades of worsening symptoms), greater clarity of thinking, and improved overall well being. I have seen other people get good results with a variety of conditions from dysbiosis to gluten/gliadin sensitivity.
MORE ABOUT ION* GUT HEALTH
You can learn more about ION* Gut Health (Restore) on our website. Also, the Restore website offers in-depth information and videos. Here is how the Restore website and Dr. Zach Bush describe the formula:
ION* Gut Health (Restore) is a dietary supplement supplying first line defense against daily exposure to environmental and food-borne factors. It helps create an optimal environment or ecology in the gut membrane for beneficial or “good” bacteria to flourish. Beneficial gut flora protect your immune system and maintain health. Restore is a scientifically proven soil-derived mineral supplement designed to support protection of the intestinal walls.
ION* Gut Health (Restore) protects the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten, and food-borne toxins. It helps create an environment in which 20,000–30,000 different strains of beneficial gut bacteria can thrive. This is a far different mode of action from probiotics, most of which contain just 3–30 strains of beneficial bacteria.
ION* Gut Health (Restore) helps create a strong immune system along with proper gut function. Microbiome balance and tight junction integrity are known to constitute a significant part of the immune system. They directly affect DNA transcription of cells to promote optimal health and prevent a leaky gut syndrome, thereby improving gut intelligence.
Seventy percent (70%) of our immune system is found in our gut. We need tens of thousands different strains of good gut bacteria to support a healthy immune system. Clinical experience, in addition to cell culture studies, support the theory that Restore’s proprietary formula creates the optimal environment in the gut to create a tight junction barrier and maintain our health and wellness.
ION* Gut Health (Restore) is a daily liquid supplement designed to support the protection of the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten and food-borne toxins by helping to create an environment where between 20,000-30,000 different strains of good gut bacteria thrive. Most probiotics on the market contain fewer than 24 different strains of good gut bacteria.
TRY ION* GUT HEALTH
ION* Gut Health is ideal for individuals suffering from gut health issues. Yet, it is also excellent for supporting and maintaining gut health generally. That is the reason we at HPDI consider Restore important enough to designate as a foundational supplement, one of the top six supplements you need for good health.
Given the safety and effectiveness of ION* Gut Health (Restore), there is broad applicability for its use. This is especially true because gut and microbiome health are under constant assault. These assaults range from multiple environmental and lifestyle factors—including poor diets high in processed foods, antibiotics in pharmaceuticals and animal foods—to massive glyphosate (herbicide) contamination of foods, soils, air, and water.
Let ION* Gut Health be your first line of defense against assaults on your gut health, tight junctions, microbiome diversity, and immune function. As it says on the bottle, “Complete well-being begins in the gut.”
Do you know HPDI has a foundational supplements system? And that HPDI’s system of Foundational Supplements is part of the comprehensive HPDI supplements system?
Foundational supplements are basic supplements providing essential nutrients that should be the “foundation” of everyone’s daily regimen. They are the foundation of a complete nutritional supplement program. They are the like the base of a pyramid in a complete nutritional supplement program.
All six HPDI foundational supplements are designed to provide a complete range of essential nutrients to complement a healthy diet and lifestyle. They help ensure sufficient levels of nutrients necessary for good health. And they are the first supplements we recommend taking as part of a complete nutritional supplement regimen.
Foundational supplements are the cornerstone in the HPDI supplement system. That is, HPDI offers a three-tiered system of nutritional supplements: Foundational Supplements, Enhancement Formulas, and Specific-Condition Formulas. The three “tiers” combined represent a complete nutritional supplement program. When customized appropriately to meet the needs of individuals, the three tiers of nutritional supplements help create optimal health.
You can visualize the HPDI supplement system as a cone or pyramid having a base of Foundational Supplements ascending toward an apex of Enhancement Formulas and Specific Condition Formulas.
The HPDI Supplement System includes six Foundational Supplements—four primary and two secondary—including multivitamins, vitamin C/antioxidants, essential fats, and Rejuvenate! superfoods.
We further break down the six foundational supplements into “primary” and “secondary” foundational supplements. The first four (listed above) being primary and the last two (gut health and hydrogen formulas) being secondary. This doesn’t mean that gut health or hydrogen formulas are less essential, depending on the person. But typically we recommend the first four in order.
We established the original three types of foundational supplements about 1988. We have always recommended multivitamins, vitamin C and antioxidants, and essential fats, as being the most important nutritional supplements for establishing and maintaining general health.
We later added high-RNA foods (like Rejuvenate! superfoods) as a fourth type of foundational supplement because research indicates dietary nucleic acids are essential nutrients—see our many articles on dietary nucleic acids, Dr. Benjamin S. Frank, and about Rejuvenate! superfoods (Original Greens, PLUS, and Berries & Herbs).
Two categories of foundational supplements were added more recently: gut health formulas (especially Restore) and hydrogen formulas. Hank wrote an article (Amending the HPDI Foundational Program) about these changes in April 2016. We added these two categories after much consideration regarding their benefits, and have written extensively about them (see Resources below).
The entire HPDI supplement system is depicted (above) as a cone. The six types of foundational supplements form the base of the cone. Enhancement Formulas and Specific-Condition formulas sit above toward the apex.
Ultimate Protector Nrf2 formula is a foundational supplement in the vitamin C / antioxidant category.
FOUNDATIONAL SUPPLEMENTS: BEST PRACTICES
I recommend using all six types of HPDI foundational supplements. I personally take the following supplements (below) and present them here as an example of how they can be integrated into a complete supplement regimen. Foundational Supplements I take:
Taking one supplement from each of the six foundational supplement categories helps build, support, and maintain optimal health.
We at HPDI recommend everyone take one of each type of foundational supplement. That is, we suggest an individual select for personal use a multivitamin, vitamin C/antioxidant formula, essential fats formula, Rejuvenate!™ superfood (or other high-RNA superfood), hydrogen product, and at least one gut health product (typically RESTORE) depending on their gut-health needs).
Likewise, we suggest health care professionals recommend for their clients one of each of the six types of foundational supplements.
The other two categories in the HPDI nutritional supplement system are Enhancement Formulas and Specific-Condition Formulas (see cone diagram). These are not foundational supplements. However, I include the supplements I take in these categories to show how Enhancement and Specific-Condition Formulas fully integrate with Foundational Supplements to form a complete supplement program providing not only essential nutrients required for health, but also particular nutrients required by me. This makes the system fully “customizable” to individual needs.
Thus, I take supplements from all three categories (Foundationals, Enhancements, and Specific-Condition) in the HPDI supplement system. However, I always prioritize foundational supplements—I take them first—because they are the all-important “base” on which my personal supplement program rests.
Foundational supplements ideally are the base on which your supplement program—or those of your clients—rests, as well.
We have seen the results of taking a complete set of foundational supplements. They work because the nutrients they provide are needed by everyone.
Muti Two Caps is a high-potency multivitamin with advanced forms for optimal utilization in the body.
SYNERGY OF FOUNDATIONAL SUPPLEMENTS
Individuals who use all six types of foundational supplements do best in terms of optimizing health. The reason is that all six foundational supplements provide nutrients required for good health.
All six types of foundational supplement provide unique benefits. Yet, each performs functions required by the human body for good health. That is one reason when they are combined they exert synergistic effects for health going far beyond the benefits just using a few types of foundational supplements, depending on individual needs, of course.
A SYSTEM OF FOUNDATIONAL SUPPLEMENTS IS NECESSARY
Individuals benefit from a structured system of supplements that can be tailored to their needs. Otherwise basic nutrients may be left out from daily intake.
For example, I know people who may or may not take a multivitamin. And they may or may not take vitamin C. Yet, they may take calcium for their bones, glucosamine for their joints, and lutein for their eyes. Or they may take a low-potency multivitamin providing merely the RDA for all nutrients.
It is fine that individuals take supplements they regard as important or useful. But that does not guarantee that a wide range—and sufficient levels—of nutrients necessary for health are available to the body on a regular basis.
In fact, I regard the supplement intake programs of most persons to be “hit-or-miss.” They may consume nutrients important for a few functions in the body, yet fail to obtain other essential nutrients required for the nutrients they take to work most effectively. We have written extensively on this topic on our website and in blog articles (see below).
Not taking regularly a complete set of foundational supplements likely means key nutrients (and key levels of nutrients) go missing. Over time, this means fewer and lower levels of nutrients available to support the body’s needs for them at levels known to sustain the good health.
The best way to ensure a sufficient range of nutrients at plentiful levels is to take foundational supplements. After a baseline of nutrients is established by taking foundational supplements, additional supplements can be added, as necessary. Following such a system and using it to customize a personal supplement regimen means there is a far better opportunity to obtain essential nutrients on a daily basis. And not to miss nutrients that help create optimal health.
High-RNA foods like Rejuvenate! PLUS superfood provide dietary nucleic acids important for health.
A COMPLETE SUPPLEMENT SYSTEM INCLUDES FOUNDATIONAL SUPPLEMENTS
After obtaining sufficient levels of basic nutrients required for health, then a person can add (or you can recommend) specific nutrients or formulas that target certain problems or issues. This is the basis for HPDI’s creation of Enhancement Formulas and Specific-Condition Formulas.
Nutritional supplements in the categories of Enhancement Formulas and Specific-Condition Formulas “stack” on top of HPDI’s Foundational Supplements (see cone diagram above). In this way, a complete nutritional supplement program begins with the most essential nutrients and continues with customizations based on the unique needs of an individual.
Enhancement Formulas in the HPDI system are supplements we regard as falling into the next tier in terms of importance, at least for most people. They do not necessarily provide essential nutrients, and yet many people (including myself) benefit significantly from them.
In the HPDI system, individuals can add (in a modular way) various formulas and single nutrients designed to support a particular set of needs or a target a specific condition.
We offer a complete range of supplements (almost 100) including a range of supplements formulated to address specific conditions. These include Joint Health Formula, Eye & Vision Formula, Blood Sugar Support, Allergy Support, Prosta Plus, Intestinal Rejuvenation Formula, and many other formulas.
ONE SYSTEM. THREE TIERS. HPDI NUTRITIONAL SUPPLEMENTS.
HPDI Foundational Supplements collectively form the base tier of a complete nutritional supplement system comprised of three tiers: 1) Foundational Supplements (six types), 2) Enhancement Formulas (or simply “Enhancements”), and 3) Specific-Condition Formulas.
Foundational Supplements are necessary because they provide nutrients foundational to health. Taking them daily or recommending your clients take them daily can help mean big differences in health, nutrition, and quality of life.
We at HPDI design our nutritional supplements to be the most effective dietary supplements available. HPDI products are known for: 1) Advanced Formulation (including use of superior forms of nutrients), 2) Ultra-High Purity, 3) Avoidance of Harmful Ingredients, and 4) being made with Good Manufacturing Practices (GMP). For more details, please see The HPDI Difference and our Statement on Additives (Excipients).
At least 40 of HPDI’s products are formulated by Dr. Hank Liers. They fall in all categories in HPDI’s supplement system. They can be found under “Dr. Hank Liers original formulas.”
Essential Fats Plus E provides well-balanced omega-3 and omega-6 fatty acids.
ADDENDUM: THE BODYSYNC GENETIC TEST & ACTION PLAN
In recent years, genetic tests have become available that show gene variations can cause or predispose a person to serious conditions relating to important body functions such a lessened ability to process synthetic B vitamins (like folic acid), higher blood glucose levels, lower immune system function, and bone density problems relating to variants in the vitamin D receptor (VDR) gene, for example.
We recommend a genetic test to determine whether individuals have certain gene variations impacting health. HPDI has teamed with a genetic testing company (BodySync, Inc.) and sells BodySync test kits on our Reseller site. To read about the BodySync genetic test and test kits click here. Genes tested for in the Bodysync test include variations in genes impacting folate assimilation, cardiovascular health, detoxification, bone health, and more. Resellers can purchase the test kits directly from HPDI and retail customers can call us (800-228-4265) to find out how we can help them get a test kit and support them with any associated counseling regarding the results.
Genetic testing allows individuals to gain a clearer picture of where they may require additional or specific nutritional supplementation. In this respect, HPDI foundational supplements can play a significant role in providing the amounts and range of important nutrients that can help mitigate the adverse effects of certain gene variations in addition to diet, exercise, and lifestyle factors. After testing, you will receive a Bodysync Action Plan that makes recommendations for a healthy diet and lifestyle customized to your unique genetic profile.
We frequently get questions from HPDI clients and resellers regarding foundational supplements. These questions include:
“Why did you add gut health and hydrogen products to your foundational supplements program?”
We found it necessary to add categories for gut health and hydrogen because they provide nutrients that are support the body and help ensure the foundational supplement system supports health most effectively. You can read more in previous blog articles (see below).
“Which is the better multivitamin: Multi Two or Mighty Multi-Vite!™?” It depends on whether you need more B vitamins or antioxidants. Multi Two provides more B vitamins and Mighty Multi-Vite™ provides more antioxidants and cofactors. I take a separate HPDI B-Complex-50 formula, so I take Mighty Multi-Vite!™ as my primary multivitamin.
“What are the differences between Rejuvenate!™ Original, PLUS, and Berries & Herbs superfoods?” They each provide about 340 mg of dietary nucleic acids. Original is the “greenest” with a large percentage of dietary nucleic acids coming from chlorella and spirunlina. PLUS is our most popular and 30% is identical to Original with more protein and a built-in multivitamin complex. Berries & Herbs contains no greens, yet more nucleic acids (390 mg), protein, and a built-in multivitamin. See our Rejuvenate! comparison page for more information.
“Should I take a vitamin C formula with antioxidants like PRO-C or one with Nrf2 activators like Ultimate Protector?” Both provide vitamin C and Nrf2 activators, but Ultimate Protector provides more types of Nrf2 activators. Ultimate Protector capsules are smaller than PRO-C capsules, so a daily dose may require taking more capsules.
“How important are hydrogen supplements?” Very important for energy production, recovery, antioxidant functions, and gut health. Hydrogen supplements like VR Tablets and Megahydrate ensure high levels of hydrogen are available in the body.
What are your best products for supporting gut health? It depends on your needs: cleansing (Intestinal Rejuvenation Formula), probiotic/microbiome support, or tightening tight junctions in the gut (RESTORE)? We offer products for all these purposes. Typically, the first gut health formula we recommend is RESTORE because so many people require extra support for microbiome health and to restore gut integrity.
These are just a few questions frequently asked about HPDI foundational supplements. If you need more information about products, please contact the HPDI office (800-228-4265) or email firstname.lastname@example.org.
You can also contact Fred Liers, PhD or Hank Liers, PhD (formulator) with questions you may have regarding specific products, single nutrients, or formulation.
I came away from Dr. Bassler’s talk with a new understanding of who we are and how we are influenced by bacteria. The fact that our bodies house ten times the number of bacteria than the number of cells in our bodies and 100 times the amount of DNA compared to our human DNA is very impressive!! Of particular note was the fact that bacteria conduct both intraspecies and interspecies communication using carbon-based hormones.
TIGHT JUNCTIONS RESTORE GUT HEALTH
Since that time my company switched to a soil-based organisms (SBO) probiotic formula called Prescript-Assist as our main probiotic formula. The formula includes a “prebiotic” called leonardite.
Leonardite is a natural form of humates that is completely organic in nature and provides ideal conditions for “good” bacteria to grow. It is a soft, waxy, black or brown, shiny, vitreous mineraloid that is easily soluble in alkaline solutions.
Leonardite is an oxidation product of lignite, a soft, brown combustible sedimentary rock formed from naturally compressed peat. Lignite has a carbon content of 25–35% and embedded in the carbon are special carbon-based molecules that were produced by soil bacteria millions of years ago.
The amazing part of this story is that Dr. Zachary Bush—a medical doctor with extensive experience in cancer research and mitochondria chemistry—made an accidental and instant connection between the special carbon molecules of lignite and special redox molecules found in mitochondria.
Based upon his recognition of these similar molecules, he developed a formula using the lignite bacterial produced carbon molecules. He found that by adding certain trace minerals and amino acids under special conditions these carbon molecules were activated.
Upon giving his formula to human beings, Dr. Bush discovered dramatic and rapid increases in beneficial gut bacterial counts. That is, the human microbiome was significantly affected in a positive way. This is particularly important since it is known that the human gastrointestinal tract houses about seventy percent of our immune system.
The most amazing part of the story was then discovered. That is when the formula (called RESTORE) was given, the tight junctions in the gut were restored to their optimal condition and “leaky gut” disappeared.
What makes this discovery so special is that “leaky gut” is caused by certain toxic bacteria, gluten, antibiotics, medical anti-inflammatories, and especially the herbicide glyphosate (RoundUp) used for genetically modified (GMO) food crops. This “leaky gut” condition is endemic in our society and getting worse as we continue to take in these toxic substances in ever increasing amounts. In Dr. Bush’s experience with a very broad range of conditions, healing began to occur very quickly when RESTORE is taken.
Additionally, Dr. Bush found that when the tight junctions in the gut were restored to their optimal condition, all of the other tight junctions in the body were restored as well. These include tight junction in the blood brain barrier, the kidney tubules, blood vessels, etc. As a result many conditions in the body dramatically improved.
Dr. Bush discovered that almost all conditions of poor health are caused by chronic inflammation and he has stated that chronic inflammation is caused by a lack of communication within the cells of the body. He has clearly seen that RESTORE reinstates proper communication between the cells and greatly reduces inflammatory conditions!
HOW EXCITING!!! Based upon this almost unbelievable discovery we have decided to carry RESTORE in both 32 oz and 8 oz sizes on our retail website. We take it ourselves!!!