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REJUVENATE! PLUS SUPERFOOD — NEW IMPROVED FORMULA

Fred Liers PhD rejuvenate! plus superfoodAs if Rejuvenate! PLUS weren’t already the delicious, nutritious superfood you know and love. Now, Dr. Hank Liers, HPDI’s formulator, has enhanced the formula for a truly remarkable taste and nutrition experience, you must try for yourself to believe!

The name Rejuvenate! Plus remains, but think of it as “version 2.0” because the nutritional upgrades and taste improvements are striking.

By the way, the “new” Rejuvenate! Plus is available now, so you can look forward to a truly remarkable user experience. We are confident you will be more than pleasantly surprised.

You will not believe your tastebuds when you try the new Rejuvenate! Plus. My humble opinion? Dr. Hank (my father and HPDI’s formulator) has knocked it out of the park in his revised formula.

Reports from sample testers have been overwhelmingly positive! Individuals who loved Rejuvenate! Plus unanimously love the new formula even more. That says a lot about this reformulation.

Rejuvenate! Plus sweet green superfood

Rejuvenate! Plus 2.0 – healthy ingredients and taste at whole new level!

Other testers, who preferred our Rejuvenate! Berries & Herbs or Original Greens formulas either say they will now add Rejuvenate! Plus to their regimen, or will mix it in with their current favorite Rejuvenate! superfood.

Some individuals sampling the new formula who had never tried it before or previously did not often use Rejuvenate! Plus have decided to use it as their primary superfood—or take it daily.

We couldn’t be happier because these reports confirm the new Rejuvenate! Plus is a significant improvement over previous versions, and make our year-long effort to reformulate the product worth it. These early reports based on product samples show we have succeeded!

Some things haven’t changed: Rejuvenate! Plus remains the most popular and best-selling of all HPDI Rejuvenate superfoods. As always, it provide therapeutic levels (at least 340 mg) of dietary nucleic acids (RNA, DNA), greens (chlorella and spirulina) as in the lighter, sweeter greens (as compared to dark intense green-ness of Rejuvenate! Original greens) that both leads to slower, yet effective detoxification, and is powerfully energizing and cleansing. Rejuvenate! Plus also remains a foundational supplement that retains a complete built-in multivitamin sub-formula.

What then has changed? In short, we have changed a few ingredients, added or upgraded other ingredients, increased protein and nucleic acids (RNA) content, and created better tasting product overall. Here is a brief summary:

The “new” Rejuvenate! PLUS features (per serving):

1) 500 mg more spirulina (1,900 mg total), which actually increases the RNA content by about 15 mg

2) 2.3 grams more protein for a total of 13.9 grams

3) Almost no sugar (just 0.6 g total)

4) 2.3 g of powerful broccoli and alfalfa sprout extract powders

5) 200 mg of organic BiAloe® aloe vera powder with over 18% acemannan

6) 5-MTHF (500 mcg) — a better form of folate

6) An extremely smooth texture, and even more delicious taste—users rate as significantly better than prior versions—which says a lot because Rejuvenate! Plus already tasted great.

In short, these are the changes that make the new, improved Rejuvenate! Plus a significantly better product. Now I will delve a bit deeper into each of these changes, as well as specific changes to ingredients.

Rejuvenate! Plus superfood

The new Rejuvenate! PLUS offers major improvements for optimal health.

REJUVENATE! PLUS IS A UNIQUE, HIGH-RNA SUPERFOOD

Rejuvenate! Plus is one three high-RNA superfoods Hank Liers of HPDI intentionally formulated to provide therapeutic levels of dietary nucleic acids. In this case, that means about 340 mg of nucleic acids per serving, and that has now been increased to at least 355 mg. The fact that Rejuvenate! Plus provides such high levels of dietary nucleic acids makes it—and the entire line of Rejuvenate! superfoods—unique!

A short history lesson: Benjamin S. Frank, MD, PhD discovered the benefits of dietary nucleic acids in the 1960s and 1970s. He performed various studies on humans and animals using various intakes of dietary RNA. He concluded that nucleic acids are essential nutrients like vitamins and minerals. Nucleic acids provide a host of unique health benefits that make getting RNA in your diet important.

After reading of Dr. Benjamin S. Frank’s works (including Dietary Nucleic Acid Nutrition and Therapy and The No-Aging Diet), my father Hank Liers and I decided to formulate a line of superfoods based on the idea of providing high levels of dietary nucleic acids for optimal health. That was 10 years ago.

Rejuvenate! Original Greens launched in 2007. Rejuvenate! Plus came two years later in 2009. Then Rejuvenate! Berries & Herbs in 2010. To this day, no other company has created dedicated high-RNA superfoods like HPDI’s Rejuvenate line.

DIETARY NUCLEIC ACIDS IN REJUVENATE! PLUS

What makes Rejuvenate! PLUS—and in fact the entire Rejuvenate! line of superfoods—unique? A single serving provides therapeutic levels (340+ mg) of dietary nucleic acids (RNA, DNA, nucleotides, and nucleosides). Here are a few of the benefits and effects of nucleic acids in the body:

  • HIGHER ENERGY (ATP) PRODUCTION
  • GREATER MUSCLE MASS / STRENGTH / ENDURANCE
  • SMOOTHER SKIN / MORE YOUTHFUL APPEARANCE
  • EASIER BREATHING / “ANTI-ANOXIA” EFFECT
  • ELEVATES TISSUE OXYGENATION
  • BENEFICIAL CARDIOVASCULAR EFFECTS
  • LOWER CHOLESTEROL LEVELS
  • OVERALL PHYSICAL REJUVENATION
  • TEMPERATURE TOLERANCE (COLD/HEAT)
  • IMPROVES LONGEVITY / QUALITY OF LIFE
  • FAR GREATER SUBJECTIVE WELL-BEING

Source: Nucleic Acid Nutrition and Therapy

Nucleic acids perform so many important functions in the body that getting sufficient amounts in the your diet is probably essential, just as Dr. Benjamin S. Frank asserts. That can be difficult since historically they were obtained from fish, organ meats—foods that people today may not consume in sufficiently high amounts for a variety of reasons. These reasons may include issues of taste, emphasis on vegetarian foods, concern about heavy metals or radiation, or lack of availability.

Rejuvenate! Plus in many ways helps take the guesswork from obtaining “essential” dietary nucleic acids by providing a vegetarian, gluten free, and non-GMO source of dietary RNA—along with protein, vitamins, minerals, cofactors, and other important nutrients—in a tasty, easy-to-take powder that stays fresh for months, travels well, and can be taken in a variety of ways from smoothies to plain water!

TRY REJUVENATE! PLUS

You (or your clients) have everything to gain by trying Rejuvenate! PLUS. As you can see, the updated superfood is carefully formulated to help create and maintain optimal health.

When used together with other HPDI foundational supplements and the HPDI supplement system, Rejuvenate! Plus is another “brick in your wall” of good health and can make a huge difference in terms of how you feel, perform, and function in life.

Try the new, improved Rejuvenate! PLUS “2.0” superfood. See for yourself not only how good it tastes, but how good it can help make you feel. That’s goodness all around!

RESOURCES

Articles

Nine Things to Know About Rejuvenate Superfoods

Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 1

Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 2

Super-Tasty Morning Nutritional Drinks

Product Reviews

Rejuvenate! PLUS Superfood is High in DNA and RNA with sprouts, chlorella & more by Mike Adams

Product Review: Rejuvenate Berries & Herbs superfood is rich in RNA, plant proteins by Mike Adams

Superfood for Cellular Survival by Dr. Mark Sircus

Books

Nucleic Acid Nutrition and Therapy by Benjamin S. Frank, MD, PhD

Dr. Frank’s No-Aging Diet: Eat and Grow Younger by Benjamin S. Frank, MD, PhD

Nucleic Acid and Anti Oxidant Therapy of Aging and Degeneration by Benjamin S. Frank, MD, PhD

Nucleic Acid Therapy in Aging and Degenerative Disease–A Metabolic Approach with DNA, RNA, and Related Metabolites by Benjamin S. Frank, MD, PhD

Rejuvenate! Superfoods

Rejuvenate! Superfoods

Rejuvenate! comparison page

Rejuvenate! PLUS

Rejuvenate Berries & Herbs

Rejuvenate! Original Greens

Videos

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REJUVENATE! LEMONADE – VIDEO

Fred Liers PhD rejuvenate original superfood lemonadeLooking for a natural energy boost? Or a super-power-up, pick-me-up drink? Look no further than Rejuvenate! Lemonade. Rejuvenate! Lemonade offers all the deliciousness of fresh lemonade with the energizing and health-boosting effects of Rejuvenate!™ (Original Greens), the first superfood formulated to provide high levels of dietary nucleic acids (RNA, DNA).

In fact, Rejuvenate Lemonade is among the best—and tastiest—ways to take Rejuvenate! Original Greens. I make 12–32 ounces of Rejuvenate! Lemonade daily. It is especially refreshing in the summer, but it easy to make and drink year-round. Not only does it taste amazingly good, but delivers the all important therapeutic levels of dietary nucleic acids you need daily for good health.

All three Rejuvenate! superfoods offer major energizing effects by providing therapeutic levels of dietary nucleic acids (RNA, DNA). Rejuvenate! superfoods are the only superfoods dedicated to supplying high levels of dietary nucleic acids. Yet, Rejuvenate!™ (Original Greens) is the most densely packed with dietary RNA, providing 340 mg per serving (one small scoop)!! A single container provides 42 servings—sufficient for six weeks of daily use.

MAKE REJUVENATE!™ LEMONADE

Make Rejuvenate! Lemonade with fresh lemons or limes, maple syrup (or other natural sweeteners), purified water, cayenne pepper (optional), and Rejuvenate!™ superfood. If you don’t have fresh lemons or limes, substitute bottled lemon juice (like the Santa Cruz brand organic 100% lemon or 100% lime juice).

REJUVENATE!™ LEMONADE RECIPE

Fresh Lemons or Limes (1–2)
Purified Water (8–32 ounces)
Grade B Maple Syrup (1–2 tbsp)
Cayenne Pepper (1/4 tsp or pinch)
Rejuvenate!™ (Original Greens) (1–4 scoops)

Squeeze the lemons (using a citrus juicer or press). Aim to squeeze 2–4 tbsp juice. Mix lemon juice into your container of water. Add 1–2 tbsp maple syrup or to taste. You can also try using stevia, xylitol, or other natural sweeteners. Add a pinch of cayenne pepper (optional). Mix 1–4 scoops of Rejuvenate! (Original Greens) superfood. In hot weather, try adding a few ice cubes. Stir and enjoy!

Rejuvenate! Lemonade is excellent when modified to include small amounts of other juices (e.g., blueberry or pomegranate) of your choice, or other Rejuvenate! superfoods (Rejuvenate! Plus or Rejuvenate! Berries & Herbs).

Rejuvenate!™ Original Greens is the most nutrient-dense, and darkest-green superfood in HPDI’s Rejuvenate! line.

MAJOR BENEFITS OF DIETARY NUCLEIC ACIDS

Dietary nucleic acids offer significant benefits, including:

• Greater Energy (via increased ATP production in cells)
• Improved Endurance
• Greater Muscle Mass and Functional Strength
• Cardiovascular Benefits
• Increased Tissue Oxygenation & Anti-Anoxic Effects (easier breathing)
• Lower cholesterol levels
• Smoother Skin & More Youthful Appearance (Anti-Aging Effect)
• Detoxification Support
• Temperature tolerance (to cold/heat)
• Quality of Life and Longevity Effects
• Greater Subjective Well-Being

(Sources: Nucleic Acid Nutrition & Therapy, and Chlorella: Gem of the Orient)

SOURCES OF DIETARY NUCLEIC ACIDS
IN REJUVENATE! SUPERFOOD (ORIGINAL GREENS)

• Chlorella
• Chlorella Growth Factor (CGF)
• Nutritional Yeast
• Yeast RNA Extract

Other nutrients included known to support the uptake, assimilation, and use of dietary nucleic acids:

• D-Ribose
• Calcium Folinate
• Methylcobalamin (Vitamin B12)

These nutrients ensure the body effectively utilizes the dietary nucleic acids in Rejuvenate! Original Greens. They also help this unique high-RNA superfood support your health beyond what might be expected of the collection of individual nutrients—a process known as “synergy” that leverages the benefits of all ingredients in Original Greens into something more than the sum of its parts.

FINAL WORDS: WHY REJUVENATE! LEMONADE?

Rejuvenate!™ Original Greens was the first in the Rejuvenate! line of superfoods. More than the others, it is nutrient-dense in terms providing the richest amount of dietary nucleic acids per unit weight. It also remains the most cost-effective per serving.

While it does not contain a built-in multivitamin (like Rejuvenate! PLUS and Rejuvenate! Berries & Herbs) or a comprehensive herbal sub-formula (like Berries & Herbs), Rejuvenate!™ Original Greens remains most popular among “hard core” nutrition customers and healthy food purists, as well as individuals seeking the most rapid detoxification and cleansing effects. Does this sounds like you or your clients? Then start with “Original Greens,” make healthy RNA-rich lemonade, and enjoy all the tasty benefits!

The combination of fresh lemonade and Rejuvenate! Original Greens will help hydrate, cleanse, purify, and detox…and simply is a tasty and energy-boosting, power-up drink like no other!

Lemonade made with Rejuvenate! Original Greens packs a potent, high-RNA punch.

RESOURCES

Rejuvenate! — The Original High-RNA Superfood

Rejuvenate! Superfoods Comparison

Rejuvenate! (Original Greens)

ARTICLES

High-RNA Rejuvenate! Superfood

“9 Things to Know About Rejuvenate!™ Superfoods”

DIETARY NUCLEIC ACIDS – DR. BENJAMIN S. FRANK, PART 1

DIETARY NUCLEIC ACIDS – DR. BENJAMIN S. FRANK, PART 2

Super-Tasty Morning Nutritional Drinks

BOOKS

Chlorella: Jewel of Far East, Bernard Jensen, PhD.

Chlorella: Gem of the Orient: The Dynamic Food Discovery for Health and Healing, Bernard Jensen, PhD

Dr. Frank’s No-Aging Diet, Dr. Benjamin Frank.

Nucleic Acid Nutrition & Therapy, Benjamin S. Frank, MD

Nucleic Acid Therapy in Aging and Degenerative Disease: A Metabolic Approach with DNA, RNA, and Related Metabolites, Benjamin S. Frank (3rd ed)

A New Approach to Degenerative Disease and Aging: Effects of RNA, DNA with Other Metabolites. Dr. Benjamin S. Frank

Dr. Frank’s No-Aging Diet Cookbook, Barbara Friedlander Meyer, Marilyn Peterson, and Benjamin S. Frank, MD

Food Healing for Man (vol. 1), Bernard Jensen, PhD

HOMOCYSTEINE GENETICS – COENZYME B VITAMINS

Dr. Hank Liers, PhD homocysteine coenzyme B vitaminsWe previously published an article titled FOLATE INGREDIENTS – FOLINIC ACID & 5-MTHF in which we discuss how coenzyme folate vitamins are far superior to the synthetic folic acid form. In today’s article, I take a more in-depth look at how homocysteine is formed from methionine, how genetics affects the metabolic pathways, and how B vitamins are used in metabolic pathways.

One way to look at the metabolic pathways of methionine (an essential amino acid) is that it provides a way for the body to convert this sulfur containing amino acid either to cysteine and its key by-products glutathione, taurine, and sulfates or allows remethylation back to methionine to occur using either the Folate Cycle or the Trimethyl glycine (betaine) pathways.

Figure 1 shows these metabolic pathways including the vitamins required at each step including vitamin B6 (as P-5-P), methylcobalamin, and 5-methyltetrahydrofolate (5-MTHF). In addition, it shows the key enzymes produced by the body at each step. These enzymes include CBS (cystathione beta synthase), BHMT (betaine homocysteine methyltransferase), MS (methionine synthase), and MTHFR (methylene tetrahydrofolate reductase).

homocysteine metabolism diagram

Figure 1. Metabolic Pathways in Methionine and Homocysteine Metabolism

HEALTH ISSUES ASSOCIATED WITH HIGH HOMOCYSTEINE LEVELS

It is highly important that the various metabolic pathways function correctly to keep homocysteine at healthy levels (6–8 µmol/L). Unfortunately, high levels of homocysteine in the body (10–20 µmol/L) are a factor in a wide range of health issues, including:

  • Greater risk for heart problems, including coronary artery disease, heart attacks, stroke, high blood pressure, congestive heart failure, and abnormal cholesterol levels. This is due to increased inflammation, sometimes due to blood clotting spontaneously, and because of blockages of the major arteries.
  • Mental abnormalities such as depression, anxiety, bipolar disorder, and other mental problems are more common among people with high homocysteine
  • Migraines and headaches in a significant percentage of the population
  • In those who suffer from high homocysteine due to having nutritional deficiencies anemia, aches and pains, hearing loss, age-related macular degeneration (ARMD), slowed development, and birth defects might also be possible
  • Greater risk for dementia, Alzheimer’s disease, brain atrophy, and other cognitive problems
  • In children, skeletal and developmental abnormalities including having a curved spine or protruding chest and rib cage. Some patients appear very tall and thin, and some might also have very long, thin “spider-like” toes and fingers.
  • Behavioral problems, including ADHD, autism and other learning disabilities

ROLE OF GENETICS IN HOMOCYSTEINE METABOLISM

Ten or more years ago, questions of how genetics enters into homocysteine metabolism were unlikely to be asked. However, in recent years DNA testing has advanced and is now available to everyone (for example, see my article about Bodysync’s genetic test, DISCOVERING NUTRITIONAL NEEDS THROUGH ADVANCED GENETIC TESTING.

You may have heard a great deal about MTHFR (methylene tetrahydrofolate reductase). This gene is involved in folate metabolism and has a central role in methylation processes like repair of and building new DNA in dividing cells.

In the remethylation pathway for conversion of homocysteine to methionine, MTHFR plays a key role in converting folate into 5-MTHF which is needed along with B12 as methylcobalamin in order for the conversion to take place. Genetic variations in MTHFR have been studied in depth. Of the many variations studies the most significant ones appear to be variations of C677C such as C677T (referred to as heterozygous) or T677T (referred to as homozygous). The heterozygous variant appears in about 30–50% of the population and causes somewhat less efficiency in the conversion of folic acid to 5-MTHF. However, the homozygous variation occurs in about 10% of the population and can have serious effects due to converting little homocysteine back to methionine.

Another variation in MTHFR is called A1298A. These variations are A1298C and C1298C and will have similar effects to the C677C variations. It was interesting to me when I recently analyzed my Bodysync genetic test results showing I carry the variation A1298C (heterozygous), which indicates I may not be effectively converting homocysteine back to methionine.

Additionally, my Bodysync genetic test results also indicate that I have heterozygous variations in the CBS enzyme shown in Figure 1, as well as heterozygous variations in MTR and MTRR enzymes, which are involved with B12 levels in the remethylation pathway. These results indicate that I need to take higher levels of methylcobalamin and 5-MTHF.

IMPORTANCE OF COENZYME FORMS AND PROPER AMOUNTS OF B VITAMINS

Many of the B vitamins on the market today unfortunately are in synthetic form. The body can only use the natural coenzyme forms effectively. For example, the body needs vitamin B6 in the form of P-5-P (pyridoxal-5-phosphate), folate in the form of L-5-MTHF, and B12 in the form of methylcobalamin for proper metabolism of methionine. In some cases the body can use the synthetic forms of pyridoxine HCl, folic acid, and cyanocobalamin but pays a cost (e.g., in time and energy) by having to convert synthetic forms to coenzyme forms.

Add to the prevalence of synthetic B vitamins, the fact that genetic deficiencies are more common than previously assumed, and it becomes clear that the coenzyme forms of B vitamins in the proper amounts are extremely important.

Fortunately, I have always believed it best to include as many coenzyme forms as possible in the nutritional supplements I formulate (over the past 27 years). For example, all HPDI multivitamins include coenzymes of B1, B2, B6, B12, and folate (as 5-MTHF and folinic acid). This is uncommon in most multivitamin formulas on the market. For this reason our supplements are ideally suited to the prevention or resolution of most genetic problems regarding homocysteine.

In addition, I have always chosen to include higher amounts than most multivitamins on the market. We also make available 5-MTHF one milligram (1 mg) capsules and methylcobalamin five milligram (5 mg) sublingual tablets. When genetic variations are in play as discussed above, then providing relatively higher amounts of coenzyme B vitamins that support important requirements in the body seems necessary.

Interestingly, several other nutrients are involved in the pathways involving methionine and homocysteine. These include zinc, magnesium, and Vitamin B2. Our multivitamin formulas and magnesium formulas, especially Myo-Mag with its coenzyme B1, B2, and B6, are recommended to support these nutrient needs. Finally, it has been found that N-Acetyl-L-Cysteine (NAC) can significantly lower homocysteine (by up to 50%), most likely because its gives the body an excellent source of cysteine without have to use methionine.

SUMMARY

In this article, I have shown the value of the use of genetic testing and high-quality coenzyme B vitamins in resolving health issues associated with high values of homocysteine in the body.

 

SOURCES & RESOURCES

DISCOVERING NUTRITIONAL NEEDS THROUGH ADVANCED GENETIC TESTING.

FOLATE INGREDIENTS – FOLINIC ACID & 5-MTHF

The Homocysteine Revolution by Kilmer S. McCully, MD

Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
(Cell Death and Differentiation 11, S56–S64)

PRODUCTS

5-MTHF
(coenzyme folate)

Methylcobalamin
(vitamin B12)

B-Complex-50

HPDI Multivitamins

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KIDS VITAMINS – NO KIDDING!

Fred Liers PhD kids mighty multi multivitamin chewableLooking for a high-quality, natural KIDS MULTIVITAMIN? Me, too. Do you look in vitamin stores, natural foods stores, and online marketplaces—in vain? I have.

A couple years ago, HPDI’s formulator, my father Hank Liers, PhD decided to reformulate our already excellent kids multivitamin—the Kids Mighty-Multi!—to make it better. His intentions were good: the world’s best designer of adult multivitamins would improve the best children’s vitamin.

My quandary? While Dr. Hank was busy at work reformulating our kids multi, the existing—and uber-excellent—original Kids Mighty-Multi! went out-of-stock, and never came back. Suddenly, my seven-year-old son’s “go-to” multivitamin was gone…indefinitely!

I took action—kids vitamins became my obsession—because I wanted the best multivitamin for my child. I searched everywhere for high-quality kids vitamins. Leaving no stone unturned, we tried them all—including organic, whole food, gluten-free, vegan-friendly brands with glossy labels. Did we find good ones? Not really.

What DID we find? Well, not much—and a lot. That is, not much in the way of high potency, high-purity, or advanced forms, like coenzyme vitamins. And a lot of false promises and junk ingredients. Like sugar and corn syrup and GMO ingredients—even from “reputable” brands.

Not to mention artificial sweeteners, colorings, flavorings, as well as toxic preservatives and fillers, which are the de facto standard in conventional products. Natural products are better—not always by as much as you’d expect.

chewable kids mighty-Multi! multivitamin

Looking for a good children’s multivitamin? Look no further than chewable Kids Mighty-Multi!

MY MULTIVITAMIN WISHLIST

Now in label-induced miasmic SHOCK…I proposed a reversal of terms. I simply wanted a lot of good things—like complete, balanced nutrients—and not much in the way of toxic additives.

Reeling, I scrawled a brief manifesto or “wishlist” for my ideal kids multivitamin:

“Great taste, high-purity, balanced nutrients at optimal levels, chewable; sugar free, non-GMO. No artificial ingredients, especially toxic sweeteners like aspartame or sucralose. No harmful additives or preservatives like sodium benzoate, BHT, or propylene glycol (no antifreeze please!); a few good-for-you functional ingredients.”

Was I asking *too* much? No way. Yet, I was giving up on finding a suitable kids multivitamin. My son instead began taking an HPDI adult multivitamin (Multi Two Caps) we scaled to his sixty five-pound weight. The taste wasn’t great—so we opened capsules directly into his juices and smoothies—because he’s not ready to swallow capsules or tablets whole. At best…a partial solution.

KIDS MIGHTY-MULTI! BACK — BETTER THAN EVER!

Then. It. Happened. Lighting struck—HPDI’s Kids Mighty-Multi! is BACK! Turns out my dad finished reformulating the world’s best kids multivitamin. He broke the news with a smile. Stunned and unbelieving…I took a breath. My heart skipped a beat. Then I grabbed a bottle!

Who knew it would take two years?—and now, who cares!? This month, HPDI proudly introduces a *new* Kids Mighty Multi!. Worth the wait? Yes. Because the new version is better than ever.

I’ve thrown away my wishlist. My search is over. Yours may be, too. Because no kids multivitamin comes *close* to Kids Mighty-Multi!. See the comparison chart and nutrient table (below).

A SERIOUS VITAMIN FOR KIDS – FINALLY!

What makes the new Kids Mighty-Multi! so good, and so much better? Let me count the ways. Here is a summary of benefits before I dive into discussing them in greater detail.

• Kids and adults love the taste!

• Full-spectrum of balanced, essential nutrients needed for creating, supporting, and maintaining excellent health for your child. Includes natural coenzyme form vitamins and Krebs’ cycle bionutrients that work with young bodies to provide energy for metabolic processes, healing, and optimal health.

• Bioavailable vitamin and mineral carriers the body recognizes and can assimilate rapidly. Plus, multiple carriers of individual nutrients ensure assimilation. Chewable form speeds uptake in the body.

Variety of well-known herbal ingredients, including quercetin, grape extract, turmeric, broccoli powder, and octacosanol

Complete, balanced supply of carotenoids, including beta-carotene, lycopene, and lutein

Functional ingredients built into every aspect of the formula, including the taste-enhancing package, herbal ingredients, and cofactors. Functional ingredients serve multiple purposes in supporting health.

• Flavored using only healthy, natural sweeteners and taste enhancers, including mannitol, fructooligosaccharides (FOS) (from chicory root), organic beet root powder, natural fruit flavor, xylitol, and stevia leaf extract. Taste enhancers exhibiting additional positive benefits (i.e., prebiotic effects, cavity prevention, and antioxidant action).

• NO refined sugars, no corn syrup, and…NO GMOs!

• NO artificial colorings or flavorings, artificial sweeteners (like aspartame, saccharin, or sucralose), or hydrogenated vegetable oils

• Excludes common food source allergens like wheat, corn, soy, and dairy

• Excludes unnecessary excipients, including fillers, binders, and additives

• Foundational formula ideal for providing basic nutrients for health. A high-quality multivitamin is the first step toward a complete nutritional supplement regimen. Formulated to work well with other HPDI foundational formulas, such as vitamin C / antioxidant formulas (like PRO-C™) and essential fatty acids (like Essential Fats plus E).

Kids Multivitamin comparison chart

TASTE-ENHANCING COMPLEX: FUNCTIONAL INGREDIENTS

Kids Mighty-Multi! tastes GREAT! Kids and adults LOVE the taste. From the perspective of your child’s taste buds, that’s *all* that matters.

But I want to talk a bit about the importance of healthy sweeteners…and how the best sweeteners perform double duty as health promoters.

WHY does Kids Mighty-Multi! taste so good? (Did I mention it contains NO refined sugars—or any artificial sweeteners or flavorings?)

Because Dr. Liers created a natural taste-enhancing complex. This taste-enhancing package includes xylitol, mannitol, FOS (fructooligosaccharides), beet root juice powder, natural fruit flavors, and stevia leaf extract.

Dr. Hank selected healthy, functional ingredients—as much as possible—in order to enhance the taste. That means these taste enhancers are not only NOT unhealthy like the refined sugars, corn syrups, and artificial sweeteners I found in so many other kids vitamins. But they are GOOD for you!

Functional sweeteners and taste-enhancing ingredients in Kids Mighty-Multi! include:

Xylitol – Proven sweetener that is a polyol (sugar alcohol) known to fight cavities, improve bone health, and more! (see: http://xylitol.org/about-xylitol/)

Mannitol – Natural polyol sweetener with added benefits as an antioxidant. Mannitol surprisingly has a very powerful effect on the hydroxyl free-radical. (see: https://www.ncbi.nlm.nih.gov/pubmed/9090754). Mannitol serves double duty as a healthy sweetener and important hydroxyl radical free-radical trapper.

• Fructooligosaccharides (FOS) (from chicory root) – Naturally sweet with no or low glycemic index. It is also a prebiotic that supports the growth of beneficial bacteria.

• Beet Root Powder (organic) – Naturally sweetens and colors Kids Mighty-Multi!. Beet is a functional ingredient providing methyl donors and easily assimilable iron. Moreover, Dr. Benjamin S. Frank found beets contain an amino acid the body uses to create its own dietary nucleic acids and a nutrient important to brain function (No-Aging Diet, 81).

• Berry & Fruit Extracts / Flavors – Mixed berry, strawberry, raspberry, and pomegranate. These berry extracts provide extremely good, fruity taste—bursting with berry flavors!

• Stevia Extract – Natural sweetens with little or no glycemic value. Kids Mighty-Multi! contains a newer, improved stevia extract which is de-bittered

• Malic Acid – Provides a naturally tart taste, supports the utilization of magnesium, and feeds into the Krebs’ cycle that makes cellular energy (ATP)

Why is choosing “good-for-you” functional sweeteners and taste enhancers important?

Because despite what adults might wish, sweeteners still comprise the largest percentage of kids multivitamins by weight. That means your child will be ingesting significant amounts (of whatever these sweeteners are) relative to the size of their multivitamin.

Who wants the bulk of their child’s multivitamin intake comprised of sugars, corn syrup, sucralose, or worse (think aspartame)? This is the reason natural sweeteners providing functional benefits make all the difference for health.

COMPLETENESS MATTERS – A LOT!

Kids Mighty-Multi! is nothing if not complete. As formulated by Dr. Hank Liers, it provides therapeutic levels of all essential vitamins, minerals, cofactors, and much more.

If you read labels (like I do), you’ll see most kids vitamins are “hit-or-miss.” They provide certain nutrients, but often completely miss others—usually with no rhyme or reason. (What was its formulator thinking?)

Missing important nutrients is bad for consumers—like you and your child—because all nutrients require other nutrients to “do a body good.” It’s called synergy, and it’s the way our cells are designed to work.

That means if you obtain sufficient amounts of a specific nutrient, but not enough of another, you may be unable to effectively utilize the nutrient you have—because utilization requires the nutrient you *don’t* have. Catch-22, huh? I’ll talk more about this later.

Do your child—and yourself—a favor: choose a complete multivitamin like Kids Mighty-Multi!.

kids mighty multi multivitamin

Kids Mighty-Multi! is nothing if not COMPLETE. (Tablets in photo appear larger than actual size.)

ADVANCED FORMS OF NUTRIENTS…LIKE YOU’VE NEVER SEEN

Then, there are advanced forms of nutrients, like coenzyme B vitamins. Most kids vitamins (and adult multivitamins) offer you the B complex vitamins as synthetic forms. How can you tell? Well, coenzyme vitamin B1 in Kids Mighty-Multi! is from Thiamin Diphosphate and is very different from synthetic “thiamine HCl.” Vitamin B2 is from Riboflavin-5′-Phosphate is not synthetic “riboflavin.” The vitamin B6 is from Pyridoxal-5′-Phosphate is not “pyridoxine HCl.” And so on.

What about vitamin B12 as toxic “cyanocobalamin”? Never. Kids Mighty-Multi! provides coenzyme B12 as methylcobalamin. Other brands sometimes use this form, but then provide synthetic forms for other B vitamins. That makes sense—NOT.

Sure, coenzyme B vitamins cost more to source. But the truth is, your body requires far less coenzyme form vitamins because they are the natural forms found in foods—you easily assimilate and utilize them. Kids Mighty-Multi! doesn’t need large amounts of coenzyme vitamins to give you big benefits.

Meanwhile, synthetic forms are not as easily assimilated—most go through a complex enzymatic breakdown before the body can use them. In some cases (for example if your child lacks certain enzymes due to genetics), syntethic forms cannot be broken down—or used—at all!

Case in point: Folate. Most kids vitamins give you “folic acid,” which is synthetic vitamin B1. A large percentage of the population (including me) lacks the gene providing the enzyme required to process folic acid. If folic acid builds up in cells (because it can’t be broken down), then it can be toxic. Solution: we use coenzyme folate—or 5-MTHF (5-methyl tetrahydrofolate) in Kids Mighty-Multi!. Problem solved.

Recall I said Kids Mighty-Multi! is complete?—and the importance of completeness in a multivitamin? Well, for example, if your kids’ multivitamin only provides synthetic vitamin B6 (as Pyridoxine HCl), it won’t be convertable into its biologically active (coenzyme) form without coenzyme vitamin B1 (Riboflavin-5′-Phosphate).

Did you catch that? To convert Pyridoxine HCl (synthetic vitamin B6) to its usable coenzyme form Pyridoxal-5′-Phosphate, you need coenzyme Riboflavin (Riboflavin-5′-Phosphate). You need a coenzyme form of one B vitamin in order to convert another B vitamin to its coenzyme form!

If you have only synthetic forms of these B vitamins, your body must go through multiple conversion processes in order to first convert synthetic Riboflavin into coenzyme Riboflavin so that you can convert synthetic vitamin B6 (Pyridoxine HCl) into its coenzyme B6 form (Pyridoxal-5′-Phosphate).

Yes, you can *survive* on synthetic forms of B vitamins. But why make your body work so hard? Why survive when you can *thrive* (with coenzyme vitamins)?

Why other kids vitamins don’t include coenzyme forms is BEYOND ME. If other brands go with conventional (and sometimes toxic) synthetic forms, so be it. Run, and go with Kids Mighty-Multi!.

Other advanced forms include vitamin D as D3 (cholecalciferol), vitamin K as K1 and K2 (Menaquinone-7), and minerals using Krebs’ cycle carriers (like citrates, malates, fumarates, succinates, and aspartates) that are best recognized and utilized in the body because they plug into the body’s energy (ATP) production system.

KIDS MIGHTY-MULTI!™ NUTRIENT TABLE

NUTRIENT

AMOUNT

% Daily Value

Vitamin A
(as beta-carotene from Dunaliella salinas)
470 IU 10
Vitamin C
(from potassium, magnesium, and calcium ascorbates)
16 mg 27
Vitamin D3 (as cholecalciferol) 50 IU 13
Vitamin E (from d-alpha tocopheryl succinate and 5 mg natural mixed tocopherols) 13 IU 42
Vitamin K (10 mcg as phylloquinone (K1) and 5 mcg as MK-7 (K2)) 15 mcg 18
Vitamin B1 (from thiamin diphosphate) 1.6 mg 107
Vitamin B2 (from riboflavin-5′-phosphate) 1.6 mg 94
Vitamin B3 (80% from niacinamide and 20% from niacin) 12 mg 60
Pantothenic Acid (from calcium pantothenate) 5 mg 50
Vitamin B6 (from pyridoxal-5′-phosphate) 2.5 mg 125
Vitamin B12 (as methylcobalamin) 15 mcg 250
Folate (from 5-MTHF – Quatrefolic®†) 50 mcg 13
Biotin (pure crystalline) 30 mcg 10
Magnesium (from malate) 6 mg 1.5
Calcium (from Krebs cycle bionutrients) 6 mg 0.6
Potassium (from citrate) 4.7 mg <1
Zinc (from citrate) 1.25 mg 8.3
Iron (from fumarate) 0.3 mg 1.7
Manganese (from citrate) 0.3 mg 15
Copper (from aspartate) 0.125 mg 6.3
Chromium (from polynicotinate) 13 mcg 11
Molybdenum (from citrate) 6 mcg 8
Selenium (from l-selenomethionine) 5 mcg 7
Choline (from bitartrate) 6 mg *
Inositol (pure crystalline) 15 mg *
N-Acetyl-L-Cysteine (NAC) 5 mg *
L-Taurine 5 mg *
Betaine HCl 3 mg *
Quercetin (as dihydrate) 3 mg *
Turmeric (from Curcuma longa) (root) 3 mg *
Broccoli Sprouts Powder 2 mg *
Grape Extract (Vitis vinifera) (from seed, skin, and stem) 1 mg *
Lycopene (tomato extract) (fruit) 200 mcg *
Boron (from glycinate and aspartate) 125 mcg *
Lutein (from Calendula officinalis) (flower) 70 mcg *
Octacosanol (from policosanol) 15 mcg *
Vanadium (from BGOV – bis glycinato oxo vanadium) 6 mcg *

* No established Daily Value
† Quatrefolic® is a registered trademark of Gnosis SPD

SCALABLE DOSING – CALLING ALL KIDS – AND ADULTS!

Maybe the best feature of Kids Mighty-Multi! is scalable dosing. Scalability makes it suitable for children and youth of all sizes—and adults, too!

Glancing at Kids Mighty-Multi!‘s label, you might assume it’s as low potency as the most kids’ vitamins available in stores. Not so fast.

Because Dr. Hank designed this multivitamin for everyone, including adults. How do I know? Because he told me: he takes these chewables himself!

How does it work? You simply take two (2) tablets per 20 pounds of body weight—up to six tablets—for kids. But since most older kids and adults weigh more than 60 pounds, you can take 8–10+ tablets and approximate the nutrition you would get from your regular adult vitamin. How cool is that!

Scalable dosing works well for people who don’t like swallowing capsules or tablets, or who prefer a good-tasting chewable. And who doesn’t, sometimes? It is especially useful for traveling because the entire family can use it.

In my case, I usually take four capsules per day of Hank & Brian’s Mighty Multi-Vite! , which my favorite adult multivitamin, and the inspiration for creating the Kids Mighty-Multi!. Yet, there are many days when I thrill to the taste of the new chewable kids multivitamin—knowing I get a significant amount of nutritional value. That means a lot. A lot of goodness. And not much to worry about.

Chewable Kids Mighty-Multi! multivitamin

Dr. Hank Liers pulled out the stops in formulating Kids Mighty-Multi!

CHOOSE KIDS MIGHTY-MULTI!

You’ve got choices. You can go online or to your local natural market, pharmacy, or big box store and fill up on whatever kids vitamins you find. Take your chances. Or you can try Kids Mighty-Multi! to discover how good a children’s multivitamin can (and should) be—a truly superior formula.

Choose our awesome kids multivitamin. Dr. Hank did his job. We’re 110% confident it meets—or exceeds—the needs and expectations of your child, and likely you, too. And definitely those of your clients, if you’re a health professional.

Of course, you’ve got a brain. But this choice is a “no-brainer.” Go for Kids Mighty Multi!. Your kids will never go back to their old multivitamin. And they’ll be healthier for it.

 

SOURCES & RESOURCES

Products

Kids Mighty-Multi! Multivitamin

HPDI Multivitamins

References

Coenzyme Vitamins (HPDI)

Fructooligosaccharides Abstracts (HPDI)

Statement on Additives (Excipients) (HPDI)

The HPDI Difference: Four Pillars of Excellence

Percent Daily Values (DV) Calculation Table (FDA)

Xylitol.org

Dr. Frank’s No-Aging Diet
by Benjamin S. Frank, MD, PhD

Studies

Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro.” Res Commun Mol Pathol Pharmacol. 95(2):179-89.
(Study includes mannitol benefits)

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ULTIMATE PROTECTOR INGREDIENTS – STRAWBERRIES

Dr. Hank Liers, PhD biography about us HPDI integratedhealth formulator founder CEO scientist physicist strawberriesUltimate Protector™ contains freeze dried strawberries, as well as components from 29 different fruits, vegetables, and herbs. Each of these ingredients contain substances that may be considered to be polyphenols, antioxidants, and Nrf2 activators. In this article I explore the ingredient strawberries, which is a component of VitaBerry Plus® from Futureceuticals.

VITABERRY PLUS®

VitaBerry® (N1023) is the trade name for a line of high ORAC blends of fruit powders and fruit extracts, exclusively available through FutureCeuticals.

VitaBerry® is a proprietary formula that combines wild bilberry and wild blueberry, cranberry, raspberry, strawberry, prune, cherry, and grape whole powders and extracts into lines of custom blends. High in fruit polyphenols, anthocyanins, proanthocyanins, ellagic acid, chlorogenic acid, resveratrol, and quinic acid, VitaBerry offers 6,000 ORAC units in a single gram.

VitaBerry® Plus (N81.3) combines the standard blend of VitaBerry® with resveratrol and quercetin to deliver a minimum of 12,000 ORAC units per gram.

Strawberry strawberries

HEALTH BENEFITS OF STRAWBERRIES

Strawberries long have grown wild in the world’s temperate regions. They have been cultivated for several thousand years and were prized among the ancient Romans. Most of the common varieties of strawberry derive from a hybrid (Frangaria x ananassa). Strawberries have an ORAC value of 1,540, which is very high among the fruits and vegetables tested by the USDA. They are a good source of vitamins C, K, B2, B5, B6, and folate. They also contain appreciable amounts of the minerals manganese, iodine, and potassium, as well as dietary fiber.

Like other berries, the antioxidants contained in strawberries may be useful against diseases of the heart and arteries by preventing the oxidation of lipids. The phytonutrient phenols most abundant in strawberries are anthocyanins and ellagitannins. The anthocyanins help to prevent oxidative damage from free radicals in body. The unique phenol profile of the strawberry enables it not only to protect the heart, but also to fight inflammation. Studies have shown that strawberries also protect the brain from oxidative stress and may therefore reduce age-related cognitive decline in brain function. Strawberries have been shown to be Nrf2 activators that can stimulate the endogenous production of protective enzymes in the body.

Here is a list of the antioxidant and anti-inflammatory phytonutrients in found in strawberries.

  • Anthocyanins
    • cyanidins
    • pelargonidins
  • Flavonols
    • procyanidins
    • catechins
    • gallocatechins
    • epicatechins
    • kaempferol
    • quercetin
  • Hydroxy-benzoic acids
    • ellagic acid
    • gallic acid
    • vanillic acid*
    • salicylic acid
  • Hydroxy-cinnamic acids
    • cinnamic acid
    • coumaric acid
    • caffeic acid
    • ferulic acid
  • Tannins
    • ellagitannins
    • gallotannins
  • Stilbenes
    • resveratrol

For more information on strawberries visit: http://www.whfoods.com/genpage.php?tname=foodspice&dbid=32

Scientific Studies on the Antioxidant Effects of Strawberries

Below, I provide relevant scientific studies on the antioxidant effects and potential health benefits of strawberries.

Strawberry as a functional food: an evidence-based review

From: http://www.ncbi.nlm.nih.gov/pubmed/24345049

Abstract

Emerging research provides substantial evidence to classify strawberries as a functional food with several preventive and therapeutic health benefits. Strawberries, a rich source of phytochemicals (ellagic acid, anthocyanins, quercetin, and catechin) and vitamins (ascorbic acid and folic acid), have been highly ranked among dietary sources of polyphenols and antioxidant capacity. It should however be noted that these bioactive factors can be significantly affected by differences in strawberry cultivars, agricultural practices, storage, and processing methods: freezing versus dry heat has been associated with maximum retention of strawberry bioactives in several studies. Nutritional epidemiology shows inverse association between strawberry consumption and incidence of hypertension or serum C-reactive protein; controlled feeding studies have identified the ability of strawberries to attenuate high-fat diet induced postprandial oxidative stress and inflammation, or postprandial hyperglycemia, or hyperlipidemia in subjects with cardiovascular risk factors. Mechanistic studies have elucidated specific biochemical pathways that might confer these protective effects of strawberries: upregulation of endothelial nitric oxide synthase (eNOS) activity, downregulation of NF-kB activity and subsequent inflammation, or inhibitions of carbohydrate digestive enzymes. These health effects may be attributed to the synergistic effects of nutrients and phytochemicals in strawberries. Further studies are needed to define the optimal dose and duration of strawberry intake in affecting levels of biomarkers or pathways related to chronic diseases.

Bioactive Compounds and Antioxidant Activity in Different Types of Berries

Abstract

Berries, especially members of several families, such as Rosaceae (strawberry, raspberry, blackberry), and Ericaceae (blueberry, cranberry), belong to the best dietary sources of bioactive compounds (BAC). They have delicious taste and flavor, have economic importance, and because of the antioxidant properties of BAC, they are of great interest also for nutritionists and food technologists due to the opportunity to use BAC as functional foods ingredients. The bioactive compounds in berries contain mainly phenolic compounds (phenolic acids, flavonoids, such as anthocyanins and flavonols, and tannins) and ascorbic acid. These compounds, either individually or combined, are responsible for various health benefits of berries, such as prevention of inflammation disorders, cardiovascular diseases, or protective effects to lower the risk of various cancers. In this review bioactive compounds of commonly consumed berries are described, as well as the factors influencing their antioxidant capacity and their health benefits.

Dietary intakes of berries and flavonoids in relation to cognitive decline

From: http://www.ncbi.nlm.nih.gov/pubmed/22535616

Abstract

Objective: Berries are high in flavonoids, especially anthocyanidins, and improve cognition in experimental studies. We prospectively evaluated whether greater long-term intakes of berries and flavonoids are associated with slower rates of cognitive decline in older women.

Methods: Beginning in 1980, a semiquantitative food frequency questionnaire was administered every 4 years to Nurses’ Health Study participants. In 1995–2001, we began measuring cognitive function in 16,010 participants, aged ≥70 years; follow-up assessments were conducted twice, at 2-year intervals. To ascertain long-term diet, we averaged dietary variables from 1980 through the initial cognitive interview. Using multivariate-adjusted, mixed linear regression, we estimated mean differences in slopes of cognitive decline by long-term berry and flavonoid intakes.

Results: Greater intakes of blueberries and strawberries were associated with slower rates of cognitive decline (eg, for a global score averaging all 6 cognitive tests, for blueberries: p-trend = 0.014 and mean difference = 0.04, 95% confidence interval [CI] = 0.01–0.07, comparing extreme categories of intake; for strawberries: p-trend = 0.022 and mean difference = 0.03, 95% CI = 0.00–0.06, comparing extreme categories of intake), after adjusting for multiple potential confounders. These effect estimates were equivalent to those we found for approximately 1.5 to 2.5 years of age in our cohort, indicating that berry intake appears to delay cognitive aging by up to 2.5 years. Additionally, in further supporting evidence, greater intakes of anthocyanidins and total flavonoids were associated with slower rates of cognitive decline (p-trends = 0.015 and 0.053, respectively, for the global score).

Interpretation: Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.

Addition of strawberries to the usual diet decreases resting chemiluminescence of fasting blood in healthy subjects-possible health-promoting effect of these fruits consumption

From: http://www.ncbi.nlm.nih.gov/pubmed/24912053

Abstract

OBJECTIVE: Regular strawberry consumption augmented plasma antioxidant activity and decreased lipid peroxidation suggests preventive potential of these fruits against oxidative stress-dependent disorders. Blood phagocytes are important source of oxidants that may contribute to systemic oxidative stress. We examined the effect of strawberry consumption on the luminol enhanced whole blood chemiluminescence (LBCL) reflecting oxidants generation by circulating phagocytes in healthy subjects.

METHODS: Thirty-one healthy subjects (being on their usual diet) consumed 500 g of strawberry pulp daily (between 11.00-14.00) for 30 days (1st strawberry course) and after 10 day wash-out the cycle was repeated (2nd strawberry course). Fasting blood and spot morning urine samples were collected before and after each strawberry course for measuring resting and agonist (fMLP)-induced LBCL, various phenolics and plasma antioxidant activity. Twenty subjects served as a control in respect to LBCL changes over the study period.

RESULTS: Strawberry consumption decreased median resting LBCL and this effect was more evident after the 1st course (by 38.2%, p < 0.05) than after the the 2nd one (18.7%), while fMLP-induced LBCL was constant. No changes in LBCL were noted in controls. Strawberries increased fasting plasma levels of caffeic acid and homovanillic acid as well as urolithin A and 4-hydroxyhippuric acid in spot urine. Plasma antioxidant activity and the number of circulating phagocytes did not change over the study period. Resting LBCL correlated positively with the number of circulating polymorphonuclear leukocytes at all occasions and negative correlation with plasma 4-hydroxyhippuric acid was noted especially after the first strawberry course (r = -0.46, p < 0.05).

CONCLUSIONS: The decrease in resting LBCL suggests that regular strawberry consumption may suppress baseline formation of oxidants by circulating phagocytes. This may decrease the risk of systemic imbalance between oxidants and anti-oxidants and be one of mechanisms of health-promoting effect of these fruits consumption.

Consumption of strawberries on a daily basis increases the non-urate 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging activity of fasting plasma in healthy subjects

From: http://www.ncbi.nlm.nih.gov/pubmed/25120279

Abstract

Strawberries contain anthocyanins and ellagitanins which have antioxidant properties. We determined whether the consumption of strawberries increase the plasma antioxidant activity measured as the ability to decompose 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) in healthy subjects. The study involved 10 volunteers (age 41 ± 6 years, body weight 74.4 ± 12.7 kg) that consumed 500 g of strawberries daily for 9 days and 7 matched controls. Fasting plasma and spot morning urine samples were collected at baseline, during fruit consumption and after a 6 day wash-out period. DPPH decomposition was measured in both deproteinized native plasma specimens and pretreated with uricase (non-urate plasma). Twelve phenolics were determined with HPLC. Strawberries had no effect on the antioxidant activity of native plasma and circulating phenolics. Non-urate plasma DPPH decomposition increased from 5.7 ± 0.6% to 6.6 ± 0.6%, 6.5 ± 1.0% and 6.3 ± 1.4% after 3, 6 and 9 days of supplementation, respectively. The wash-out period reversed this activity back to 5.7 ± 0.8% (p<0.01). Control subjects did not reveal any changes of plasma antioxidant activity. Significant increase in urinary urolithin A and 4-hydroxyhippuric (by 8.7- and 5.9-times after 6 days of supplementation with fruits) was noted. Strawberry consumption can increase the non-urate plasma antioxidant activity which, in turn, may decrease the risk of systemic oxidants overactivity.

One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans

From: http://www.ncbi.nlm.nih.gov/pubmed/24406274

Abstract

Strawberries are an important fruit in the Mediterranean diet because of their high content of essential nutrients and beneficial phytochemicals, which seem to exert beneficial effects in human health. Healthy volunteers were supplemented daily with 500 g of strawberries for 1 month. Plasma lipid profile, circulating and cellular markers of antioxidant status, oxidative stress and platelet function were evaluated at baseline, after 30 days of strawberry consumption and 15 days after the end of the study. A high concentration of vitamin C and anthocyanins was found in the fruits. Strawberry consumption beneficially influenced the lipid profile by significantly reducing total cholesterol, low-density lipoprotein cholesterol and triglycerides levels (-8.78%, -13.72% and -20.80%, respectively; P<.05) compared with baseline period, while high-density lipoprotein cholesterol remained unchanged. Strawberry supplementation also significant decreased serum malondialdehyde, urinary 8-OHdG and isoprostanes levels (-31.40%, -29.67%, -27.90%, respectively; P<.05). All the parameters returned to baseline values after the washout period. A significant increase in plasma total antioxidant capacity measured by both ferric reducing ability of plasma and oxygen radical absorbance capacity assays and vitamin C levels (+24.97%, +41.18%, +41.36%, respectively; P<.05) was observed after strawberry consumption. Moreover, the spontaneous and oxidative hemolysis were significant reduced (-31.7% and -39.03%, respectively; P<.05), compared to the baseline point, which remained stable after the washout period. Finally, strawberry intake significant decrease (P<.05) the number of activated platelets, compared to both baseline and washout values. Strawberries consumption improves plasma lipids profile, biomarkers of antioxidant status, antihemolytic defenses and platelet function in healthy subjects, encouraging further evaluation on a population with higher cardiovascular disease risk.

Impact of strawberries on human health: insight into marginally discussed bioactive compounds for the Mediterranean diet

Abstract

OBJECTIVE: To review and update the current knowledge on the potential impact of strawberry on human health, with particular attention on compounds and indirect mechanisms of action not exhaustively considered.

DESIGN: Personal perspectives and recent data.

SETTING: International.

RESULTS: Our research group was among the few groups that have recently investigated the folate content in fresh, stored and processed strawberries, and the data look very promising. As well, some in vivo evidence of the impact of strawberry intake on the folate status in humans have already been reported, but a new increasing interest on this field is strongly hoped. Furthermore, the hypouricaemic effects previously ascribed to cherry consumption need to be evaluated in respect to strawberry intake. At the moment, inconsistent results come from the few investigations designed at this proposal. In our studies, a great interindividual variability was observed on plasma urate levels in response to strawberry intake, suggesting a putative effect.

CONCLUSIONS: The mechanisms responsible for the potential health-promoting effects of strawberry may not be necessarily searched in the activity of phytochemicals. Particularly, a greater interest should be addressed to show whether a prolonged strawberry consumption may effectively improve the folate status and reduce the incidence of folate-related pathological conditions. Furthermore, the hypouricaemic effects of cherries need to be evaluated also in respect to strawberry intake, and the mechanisms of actions and anti-gout potentialities need to be studied in detail. Future investigations involving human trials should be aimed at following these underestimated scientific tracks.

strawberry strawberries fruit

SUMMARY

Strawberries are an important fruit full of polyphenols, anthocyanins, antioxidants, and Nrf2 activators that help to make Ultimate Protector such an outstanding nutritional supplement.

 

Contact Us:

You can reach HPDI by calling 1-800-228-4265, email support(at)IntegratedHealth.com, or visit the retail website: www.IntegratedHealth.com

Health care professionals and retailers can apply for wholesale account, which includes access to the HPDI reseller website: www.HealthProductsDistributors.com