In early 2012 a friend of mine told me about a new product he was taking from a company called LifeVantage. He informed me all he needed to take on a daily basis was one small tablet in order to be protected against free-radical damage of any sort. And that he didn’t even need to take Vitamin C!
I have formulated nutritional supplements for a long time, so I knew there was something not quite right about what I was hearing. When I learned he was buying from a multi-level marketing company his story became understandable, but not believable.
I decided I would investigate the product in order to better understand the logic behind it. I watched videos regarding the science underpinning this product, and I read the scientific literature for months.
What I learned was intriguing, so I decided I would formulate a product dealing with free-radical protection that would take the science and the art of formulation to new levels. I would name the product (drumroll please) “Ultimate Protector”!!
According to Dr. Joe McCord, in the last 10 years or so there have been over 80,000 papers in peer reviewed publications that relate to Nrf2 activators. Many of these have clearly demonstrated that plant polyphenols are perhaps the best way to intake substances that will stimulate the endogenous production of protective enzymes. In fact, many reputable scientists believe the best way to prevent cancer is via the use of plant polyphenols.
There are also many papers in the scientific literature that have shown the consumption of fruits and vegetables (including herbs) that are inherently high in polyphenols to be one of the best ways to improve health and prevent conditions of poor health. Please see my blog article on this subject: “The Amazing Healing Potential of Natural Nrf2 Activators” (http://www.integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/).
In the world of nutritional supplements it is not often that significant scientific/clinical studies are conducted on specific products. The reason for this is primarily economic. However, just as in the case of Nrf2 activators, hundreds of thousands of studies have been conducted by organizations around the world that show the benefits of specific ingredients or groups of ingredients, and these ingredients are used in the development of healthful nutritional supplements.
It is laudable that LifeVantage has had a few scientific/clinical studies done on their product containing five specific Nrf2 activators. This positively supports the huge amount of scientific papers on the subject. However, these few studies do not imply it is a better product than products developed using additional carefully-selected ingredients highlighted in the scientific literature. Progress is made continuously in the area of nutritional supplements allowing us to improve on existing products.
As an example of how being aware of the scientific literature on Nrf2 activators, as well as being experienced in the design of groundbreaking new nutritional products, I was recently delighted to observe that high ORAC5.0 values are associated with many of the best Nrf2 activators identified in the scientific literature. This is discussed in my blog article referenced above.
Indeed, this observation is in contrast to the statements by many (even the scientists) that taking antioxidants is unnecessary and perhaps harmful. It appears that these antioxidants may perform double duty by first operating as antioxidants in the body (including the gastrointestinal tract) and in the process become weak pro-oxidants that function as powerful Nrf2 activators. Of course, if you are not aware of ORAC5.0 testing, then it would not be possible to make such an observation.
ULTIMATE PROTECTOR GOALS
My goal when I formulated Ultimate Protector™ was to create a product with three basic functions. That is, 1) a source of non-GMO Vitamin C (1.5 gm/daily serving), 2) provide powerful antioxidant protection via proven high ORAC sources, and 3) a multiple ingredient source of many Nrf2 activators, thereby providing the body with means to produce a wide variety of protective enzymes endogenously.
VITAMIN C IN ULTIMATE PROTECTOR
It is important to realize Vitamin C is a vitamin that is a cofactor in at least eight enzymatic reactions, including several collagen syntheses reactions that when dysfunctional (usually because of lack of Vitamin C) cause the most severe symptoms of scurvy. In animals, these reactions are especially important in wound healing and in preventing bleeding from capillaries. It is important to understand that no other substance can provide these functions.
Vitamin C acts as an electron donor and/or hydrogen donor, and this ability makes it a potent antioxidant. It rapidly reduces superoxide and nitroxide radicals and scavenges hydroxyl, alkoxyl, and peroxyl radicals. It also reacts with non-radical species such as singlet oxygen and hypochlorous acid. It has been observed in in vitro experiments that Vitamin C acts as the first line of defense in the plasma. In order to learn more about the important role of Vitamin C, please see my blog article: “Vitamin C – An Amazing Nutrient” (www.integratedhealthblog.com/vitamin-c-an-amazing-nutrient/).
ORAC5.0 VALUES OF ULTIMATE PROTECTOR
The full spectrum of antioxidants derived from high ORAC fruits, vegetables, and herbs (as well as Vitamin C) provide extremely powerful exogenous sources of protection against oxidative stress. To obtain a quantitative measure of just how powerful these external sources are we elected to conduct ORAC testing.
The fact is that there are a variety of “free radicals” that operate in humans. The most important are the primary radicals hydroxyl, peroxyl, peroxynitrite, singlet oxygen, and superoxide anion. Recently, Brunswick Labs has introduced a new test called ORAC5.0™ (also known as ORACFN). This test expands the ORAC platform to measure the antioxidant capacity against each of the five primary reactive oxygen species mentioned above (not just against the peroxyl radical as ORAC does). ORAC5.0™ substantially improves broad-spectrum antioxidant analysis and gives evidence of the diverse antioxidant potential of natural products against radicals.
Brunswick Labs has tested Ultimate Protector™ using the new ORAC5.0™ tests. The results reveal an incredible overall ORAC5.0 value of 173,000 µmole TE/gram, an exceptionally high value. In addition, the results show that the formula offers excellent protection against all of the five major types of free radicals. Specifically, the results show values of 6,300 (µmole TE/gram) for peroxyl radicals, 5,900 (µmole TE/gram) for hydroxyl radicals, 2,500 (µmole TE/gram) for peroxynitrite, 106,000 (µmole TE/gram) for superoxide anion, and 52,000 (µmole TE/gram) for singlet oxygen.
The overall daily ORAC5.0™ value per serving obtained by adding the values for each free radical type is 486,000 units (173,000 units x 2.81 g)!! To the best of our knowledge there is no other product that even comes close to providing such complete protection both in terms of breadth of coverage and overall strength. The Brunswick Labs ORAC5.0™ test results for Ultimate Protector are posted on our website. View the test results.
Nrf2 CONSIDERATIONS REGARDING ULTIMATE PROTECTOR
In the development of Ultimate Protector™, I was fortunate to obtain a license regarding the use of four complex nutritional ingredients manufactured by Futureceuticals, Inc. (http://www.futureceuticals.com). FutureCeuticals uses target-specific acute clinical studies to create benefit-driven products. This type of testing is central to the company’s TargeTest™ research program.
The program focuses on a number of blood targets, including CETP, PON1, SIRT, Elastase, and ACE, among others. Acute clinical studies that show how dietary supplements affect these targets and can help product developers to identify what nutraceutical ingredients are best to include in blends designed to benefit specific health conditions.
For example, TargeTest measures an ingredient’s ability to help manage inflammation by analyzing activity of NF-κB in blood cells for two to three hours after ingestion of the ingredient. The results lead to two important conclusions. One is whether or not that ingredient is bioavailable, which is determined by measuring its effect in human blood. Second, the results can show whether or not the ingredient inhibits NF-κB. A positive result indicates that the tested ingredient could help regulate inflammation if used over a longer period of time.
The four products we have licensed are 1) AnthoComplete®, 2) CoffeeBerry®, 3) VitaBerry® Plus, and 4) VitaVeggie®. They contain a very broad variety of plant substances that have been optimized for their antioxidant value and support of human health.
The selection of these four products provides phytonutrients from 27 of the most healing fruits and vegetables, most of which are identified as Nrf2 activators in the scientific literature. These include: Wild Blueberry, Wild Bilberry, Acai, Black Currant Extract, Sweet Cherry, Raspberry, Elderberry, Blackberry, Aronia (Chokeberry), Black Soybean Hull Extract, Blue Corn, CoffeeBerry®, Grape Seed, Cranberry, Tart Cherry, Prune, Raspberry Seed, Strawberry, Quercetin, Broccoli, Broccoli Sprouts, Tomato, Kale, Carrot, Brussels Sprouts, Onion, and Spinach.
We added curcumin (95% min. curcuminoids) and resveratrol (greater than 98%) to the formula because they are important in the Nrf2 literature, and were not adequately included in the Futureceuticals products we selected. The total amount of these plant ingredients per daily serving (six veggie caps) amounts to a total of 630 mg, which is consistent with the idea expressed in the scientific literature that only small amounts are necessary for powerful Nrf2 activation.
The total combination of freeze-dried and concentrated fruits, vegetables, and herbs in Ultimate Protector provides a wide range of choices to the body in terms of specific substances, including polyphenols, phenolic acids, anthocyandins, sulforaphane, glucosinolates, lutein, lycopene, beta carotene, chlorogenic acid, ellagic acid, quercetin, quinic acid, proanthocyanidins, resveratrol, ferulic acid, caffeic acid, and polysaccharides.
After testing the final product for ORAC5.0 value we were truly amazed to find that a single serving (2.81 gm) of Ultimate Protector provides 486,000 ORAC5.0 units (see my blog article on Ultimate Protector ORAC5.0 test results at http://www.integratedhealthblog.com/orac5-0-and-ultimate-protector/). This value is more than 10 times greater than a serving size of any other product of which we are aware!! Our observation that high ORAC5.0 and effective Nrf2 activation appear to be correlated indicates that with Ultimate Protector we have made a major breakthrough in the development of nutritional supplements containing Nrf2 activators.
ULTIMATE PROTECTOR SUMMARY
Ultimate Protector has been on the market about two years. Our customers say they like it very much, including the fact that all ingredients are non-GMO and contained in a small veggie capsule with a minimal amount of excipients. Heavy metals testing indicates no detectable amounts of lead, mercury, and arsenic and insignificant amounts of cadmium per capsule. To date we have no complaints of any allergic reactions, possibly due to the purity of the ingredients. Below is a testimonial from one of our customers who posted on Amazon.com:
“This product is very powerful, after taking only one capsule I feel a tremendous balanced energy take over, and my thinking is razor sharp. This may not be everyone’s experience as I am super sensitive. This product is for real!!!!” – By Adam D Da Virro on April 10, 2014
We hear similar reports from many other customers, including a few enthusiastic ones who have written entire blog articles about Ultimate Protector. We often hear about increased energy levels, enhanced mental acuity, improved capacity to combat illness (e.g., colds and flu), and overall greater well-being. These are just a few benefits reported to us by customers using the formula.
I am especially pleased because I succeeded in formulating a product from which everyone can truly benefit, not only individuals seeking optimal mental or physical performance, such as athletes. And we see it happening every day.
We encourage you to learn the facts, and consider trying Ultimate Protector. While it is formulated as a foundational supplement designed for best results to be taken daily along with a high-potency multivitamin, essential fats, and Rejuvenate! superfoods, it’s also highly effective when used alone. Given the remarkable benefits Ultimate Protector provides, you’ve got nothing to lose and everything to gain.
Learn more about Ultimate Protector™.
HPDI BLOG ARTICLES
- Questions & Answers about Ultimate Protector
- The Amazing Healing Potential of Natural Nrf2 Activators
- New Directions For Preventing Free-Radical Damage
- Natural Phytochemical Nrf2 Activators for Chemoprevention
- Ultimate Protector™ Brunswick Labs ORAC5.0™ Test Results
- Description and Comparison of ORAC Tests for Well Known Plant Ingredients and Ultimate Protector™
- Ultimate Protector™: First Impressions
- Preventing Free-Radical Damage Using Ultimate Protector™
- PRO-C™ Super Antioxidant Formula