Why Nutritional Supplements are Vital for Optimal Health

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Dr. Hank Liers, PhD foundational supplements multivitamin formula vitaminsFred Liers PhD vitamins multivitamins nutritional supplementsThere recently have been articles in the press which claim that because a certain multivitamin has not shown proven reductions in cancer, heart disease, and/or other illnesses, it is therefore worthless to take a multivitamin.

Unfortunately, the authors (including doctors and other so-called ‘experts’ on nutrition who may have no training on the subject) who are writing these articles are usually quite ignorant of the facts regarding nutrition and its relation to health. That is, they simply do not understand the known facts about nutrition, lifestyle factors, toxins, stress, food quality, etc. that impact our health.

Below we clarify why it is important for your health to take nutritional supplements and recommend what basic nutritional formulas should be taken. We want to emphasize that nutritional supplements are not suggested as a replacement for a healthy diet. It is strongly suggested that you eat a natural whole foods diet that is primarily organic, eliminates genetically modified and synthetic foods, and includes a significant amount of raw vegetables and fruits.

Vitamins foundational nutritional supplements multivitamin mineral


In 25 years of working in the health field, we have observed that few people understand how to properly select supplements as part of an optimized nutritional supplements program. Too often people take a piecemeal approach to nutritional supplements.

A common scenario is that they hear from a friend or acquaintance that a particular nutrient works for a certain health issue or that another nutrient is useful for dealing with different issue, etc. They cobble together a set of nutrients that could not possibly meet their true needs.

A piecemeal approach includes, for example, persons who take an inadequate (i.e., low potency) multivitamin (often with toxic food colorings and synthetic forms of Vitamin E), yet neglect to take essential fats that are controllers of many important functions in the body! Generally speaking, this approach fails because it is misses important nutrients needed by the body.

A piecemeal approach often overly focuses on immediate issues without helping to establish intake of nutrients that create and maintain optimal health.


We at HPDI have observed that it is important for individuals to begin their nutritional supplements program with Foundational Supplement Formulas. These provides significant amounts of the basic nutrients satisfying nutritional requirements identified by research and clinical experience over the last 75 years.

We have documented this in our Foundational Supplements booklet and on the HPDI website (www.IntegratedHealth.com).

We recommend four basic types of foundational supplements (sometimes referred to “essential” or “core” formulas) representing the culmination of our experience with supplements needed for health. These four supplements include:

1) A high-quality multivitamin to provide high levels of the basic nutrients required for health, 2) essential fats that the body needs to perform many critical functions, 3) Vitamin C (with other antioxidants, especially bioflavonoids), which is required to sustain life, and 4) High-RNA superfoods, which supply critically needed nucleic acids (i.e., dietary RNA and DNA).

Four types of foundational supplements vitamins multivitamins
The Four Types of Foundational Supplements

There is less awareness among consumers about the benefits of dietary nucleic acids compared to other essential nutrients, but they are highly important for healing and health. In fact, the need for RNA was well recognized over 50 years ago when it was common knowledge that eating liver, a high RNA food, once a week was important for good health!

While we offer a very wide range of supplements, including many that support specific problems or conditions, we always recommend starting with foundational supplements because taking these four types of formulas helps build, support, and maintain the health of the body.


The reason that foundational supplements are needed is not a mystery. There is plenty of evidence supporting the body’s requirements for them. This is because during the past 70 years, nutritional scientists deeply explored fundamental questions about essential nutrients the body needs to properly function, as well as substances the body needs from outside sources because it cannot synthesize them. There are in fact, tens of thousands of studies published in peer reviewed literature supporting the body’s need for these nutrients.

The Need for Foundtional Supplements

The current scientifically accepted list of essential nutrients includes thirteen vitamins, more than twenty minerals, two essential fatty acids, nine essential amino acids, a source of calories (includes protein, carbohydrates, and fats), water, oxygen, and sunlight. We add to the list dietary nucleic acids (especially RNA) based on the reasearch of Dr. Benjamin S. Frank. Daily values (DVs) are established for most of these substances, but represent only minimum amounts needed to avoid disease. Consequently, these values do not address amounts needed for optimal health.

Regarding optimal daily values, there is a vast body of research on nutrients, which in addition to our experience, provides insights into what might be optimal amounts of nutrients for health. It is no surprise that optimal values for essential nutrients are nearly always significantly higher than established daily values. This is because minimal amounts of nutrients required for mere survival cannot sustain vibrant health.

Daily values are, in fact, probably better described as “deficiency values” because these amounts hover dangerously close to actual deficiency levels (depending on the individual) and most likely describe a state of “subclinical deficiency” (if not actual deficiency), whereby actual deficiency symptoms are temporarily masked.

 Nutrient Daily Value  Nutrient Daily Value
Total Fat 65 g Thiamin (Vitamin B1) 1.5 mg
Saturated Fatty Acids 20 g Riboflavin (Vitamin B2) 1.7 mg
Cholesterol 300 mg Niacin (Vitamin B3) 20 mg
Sodium 2,400 mg Vitamin B6 2.0 mg
Chloride 3,400 mg Folate 400 mcg
Potassium 3,500 mg Vitamin B12  6 mcg
Total Carbohydrates 300 g Biotin 300 mcg
Dietary Fiber 25 g Pantothenic Acid 10 mg
Protein 50 g Phosphorus 1,000 mg
Vitamin A 5,000 IU Iodine 150 mcg
Vitamin C 60 mg Magnesium 400 mg
Calcium 1,000 mg Zinc 15 mg
Iron 18 mg Copper 2.0 mg
Vitamin D 400 IU Manganese 2.0 mg
Vitamin E 30 IU Chromium 120 mcg
Vitamin K 80 mcg Molybdenum 75 mcg
Selenium 70 mcg


Foundational nutritional supplements provide important nutrients in amounts not easily available in the diet. This relates to the fact that our needs for nutrients have never been greater.

Our needs for nutrients are greater due to many factors, including diets high in nutrient-depleted and processed foods (e.g., refined carbohydrates), and low in fresh vegetables and fruits. This actually describes the so-called “Standard American Diet,” or “SAD,” which has been implicated for its negative health effects.

Some reasons dietary supplements are necessary include these facts:

1) Most crops are grown in nutrient-deficient and/or depleted soils using methods of industrial agriculture that fail to replenish nutrients, and poison the soil (and therefore foods) with toxic pesticides, herbicides, and chemical fertilizers, 2) Food processing methods damage, destroy, or remove many essential nutrients, 3) Increased demands by the body due to greater needs for nutrients (relating to stress, pollution, greater needs for detoxification, and other factors endemic to modern society), and 4) Biochemical individuality resulting in greater needs for certain nutrients depending on the unique biochemistry (genetic profile) of an individual.

Biochemical individuality means that someone may require many times the recommended US Daily Value for specific nutrients. Consequently, one person may need hundreds of times the amount of a nutrient compared to another person’s requirement.

Calcium 60% Strontium 95%
Chromium 40% Zinc 78%
Cobalt 89% Vitamins B1, B2, and B3    72–81%
Copper 68% Vitamin B6 72%
Iron 76% Pantothenic Acid 50%
Magnesium 85% Folate 67%
Manganese 86% Vitamin E 86%
Molybdenum 48% Linoleic Acid 95%
Phosphorus 71% Alpha-Linolenic Acid 95%
Potassium 77% Protein 33%
Selenium 16% Fiber 95%
Source: Fats That Heal, Fats That Kill by Udo Erasmus

A review of nutritional studies indicates that deficiencies of most nutrients among individuals range from 25%–95% depending on the nutrient. Such major deficiencies are less surprising given studies indicating that nutrient losses from the processing of foods range from 20%–95%, and average 70%–80%.

For example, losses due to food processing are about 85% for magnesium and 95% for essential fats (omega-3 and omega-6).

In addition, mineral levels measured in plants grown in poor soils (a result of inadequate agricultural practices) are as low as 5% of the mineral levels measured in plants grown in nutrient-rich soils.

From National Surveys From Clinician Estimates
 Nutrient % Deficiency  Nutrient % Deficiency
Calcium 68% Biotin 10%
Folate 10+% Chromium 90%
Iron 57% Copper 85–90%
Magnesium 75% Manganese 20–30%
Phosphorus 27% Pantothenic Acid 25%
Vitamin A 50% Selenium 50–60%
Thiamin (Vitamin B1) 45% Silicon 30%
Riboflavin (Vitamin B2) 34% Vitamin D 70%
Niacin (Vitamin B3) 33% Vitamin E 20–40%
Vitamin B6 80% Vitamin K 15%
Vitamin B12 34% Essential Fatty Acids 95%
Vitamin C  41% Zinc 35–60%
Source: Fats That Heal, Fats That Kill by Udo Erasmus

Complicating this picture is the fact that nutritional requirements change during the year due to environmental circumstances. Changing seasons, environments, air/water supply, etc. mean that an individual’s need for nutrients typically changes (e.g., more Vitamin D needed in the winter, more nutrients needed to cope with pollution associated with urban environments or stress, etc.).

Nutrient density of foods also varies by location and season. The availability of nutrients in foods can vary substantially due to season, geographic factors, and growing methods.

All these factors add up to indicate the difficulty of ensuring optimal nutrient status without foundational supplements. Because the need for nutrients is greater than ever for most people, the need for nutritional supplementation is also greater than ever.

Nutritional supplements provide an effective (and cost-effective) means to ensure the high levels of nutrients required to build, sustain, and maintain optimal health.


An important consideration (often overlooked because nutritional research typically examines only one or two nutrients at a time) is that hundreds of nutrients act and interact in our bodies simultaneously. Considering that the recommended (i.e., minimum) amount of a single nutrient rarely represents optimal intake, adverse effects can significantly increase when a broad range of nutrients is present only in suboptimal amounts (i.e., when there exists a deficiency of optimal amounts of nutrients).

The function of the human body might be likened to an automobile factory. If a factory is designed to optimally produce 100 vehicles per day, then the factory must be supplied with at least minimum amounts all essential raw materials to make this happen. In this case, incorrect amounts of raw materials, for example, 40 tires, 91 transmissions, 67 drive trains, 13 exhaust pipes, etc. would never allow optimal automobile production. It becomes evident that important relationships among parts must be honored for the entire system to function properly.

Like an automobile factory, the human body needs proper amounts of critical “raw materials” (i.e., basic nutrients) to perform optimally. However, the need to obtain appropriate “materials” in correct amounts is arguably more relevant for the extremely complex human body. In this regard, scientific studies on nutrients perform a disservice when they fail to consider complex interactions among nutrients in the body required to support optimal function. Minimum levels of nutrients can only lead to minimum health. Following the analogy of an auto factory, the body cannot create optimal health from insufficient raw materials (nutrients).

In fact, we have an accurate picture of what levels of nutrients support optimal body function. We are aided in this knowledge by solid scientific studies. It is established that basic nutrients provided by foundational supplements confer immense benefits for health. Indeed, basic nutrients have proven remarkably effective for improving health, especially relative to their cost. Foundational nutritional supplements are far less costly than pharmaceutical drugs or the medical procedures used to treat health conditions related to nutrient deficiencies, which often can be prevented by dietary supplements.

In addition, there is the fact that natural nutrient substances exhibit extremely low toxicity. Most vitamins, for example, demonstrate low toxicity (even at levels significantly higher than official daily values). The “2008 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 26th Annual Report” published in Clinical Toxicology (2009) indicates not a single fatality caused by nutritional supplements in the US that year. This underscores the safety of vitamins, minerals, herbs, and amino acids. While this figure may seem remarkable considering that more than half the US population takes daily nutritional supplements, it confirms the safety of natural nutrient substances. Indeed, essential nutrients are safe and effective precisely because they naturally work together within the body to create health. On the other hand, prescription drugs, even when taken properly, are a major cause of death in the US, killing over 100,000 people every year. This is a major public health threat. FDA approved, firmly regulated drugs are causing gigantic harm to the public.


Clearly, it is important for your health to take a high potency multivitamin on a daily basis. However, just taking a multivitamin allows you to be deficient in other nutrients that are required for complete basic nutrition and can lead to major deficiencies and serious health issues.

We urge our readers to become familiar with the foundational supplements we have discussed and be sure to get everything needed for optimal health!



Encyclopedia of Nutritional Supplements, Michael Murray, N.D., 1996

Nutrition and Physical Degeneration 8th edition, Weston A. Price (author), Price Pottenger Foundation (editor), 2008.

How to Live Longer and Feel Better. Dr. Linus Pauling. Corvallis, OR: Oregon State University Press, 2006.


“Vitamin C – An Amazing Nutrient” by Dr. Hank Liers

“Choosing Supplements for a Complete Nutritional Supplements Program” by Dr. Hank Liers


HPDI Rejuvenation Program


Multivitamin and mineral use and breast cancer mortality in older women with invasive breast cancer in the women’s health initiative.

Multivitamin use is common in the United States. It is not known whether multivitamins with minerals supplements (MVM) used by women already diagnosed with invasive breast cancer would affect their breast cancer mortality risk. To determine prospectively the effects of MVM use on breast cancer mortality in postmenopausal women diagnosed with invasive breast cancer, a prospective cohort study was conducted of 7,728 women aged 50–79 at enrollment in the women’s health initiative (WHI) in 40 clinical sites across the United States diagnosed with incident invasive breast cancer during WHI and followed for a mean of 7.1 years after breast cancer diagnosis. Use of MVM supplements was assessed at WHI baseline visit and at visit closest to breast cancer diagnosis, obtained from vitamin pill bottles brought to clinic visit. Outcome was breast cancer mortality. Hazard ratios and 95 % confidence intervals (CIs) for breast cancer mortality comparing MVM users to non-users were estimated using Cox proportional hazard regression models. Analyses using propensity to take MVM were done to adjust for potential differences in characteristics of MVM users versus non-users. At baseline, 37.8 % of women reported MVM use. After mean post-diagnosis follow-up of 7.1 ± 4.1 (SD) years, there were 518 (6.7 %) deaths from breast cancer. In adjusted analyses, breast cancer mortality was 30 % lower in MVM users as compared to non-users (HR = 0.70; 95 % CI 0.55, 0.91). This association was highly robust and persisted after multiple adjustments for potential confounding variables and in propensity score matched analysis (HR = 0.76; 95 % CI 0.60–0.96). Postmenopausal women with invasive breast cancer using MVM had lower breast cancer mortality than non-users. The results suggest a possible role for daily MVM use in attenuating breast cancer mortality in women with invasive breast cancer but the findings require confirmation.


(Therapeutic Nutrition Based Upon Biochemical Individuality)

The Final Word on Supplements. Yeah, Right.

Regulation of Vitamins: Politics As Usual


Foundational Supplements

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